|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1001 to 1100 out of 1952 for Cdkn2a

<< First    < Previous  |  Next >    Last >>
0.022s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
17575131 | J:122413
First Author: Yang G
Year: 2007
Journal: Cancer Res
Title: Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.
Volume: 67
Issue: 12
Pages: 5649-57
•
•
•
•
•
Publication
22986743 | J:192887
First Author: Kim HS
Year: 2012
Journal: Cancer Res
Title: Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc.
Volume: 72
Issue: 22
Pages: 6065-75
•
•
•
•
•
Publication
25609585 | J:219707
 
First Author: Zingg D
Year: 2015
Journal: Nat Commun
Title: The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Volume: 6
Pages: 6051
•
•
•
•
•
Publication
30827889 | J:277880
First Author: Ma J
Year: 2019
Journal: Cancer Cell
Title: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.
Volume: 35
Issue: 3
Pages: 504-518.e7
•
•
•
•
•
Publication
22772081 | J:193443
First Author: Shakhova O
Year: 2012
Journal: Nat Cell Biol
Title: Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.
Volume: 14
Issue: 8
Pages: 882-90
•
•
•
•
•
Publication
11818530 | J:74365
First Author: You MJ
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice.
Volume: 99
Issue: 3
Pages: 1455-60
•
•
•
•
•
Publication
17296553 | J:136794
First Author: Ligon KL
Year: 2007
Journal: Neuron
Title: Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
Volume: 53
Issue: 4
Pages: 503-17
•
•
•
•
•
Publication
34433909 | J:316091
First Author: Leonard MK
Year: 2021
Journal: Oncogene
Title: Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients.
Volume: 40
Issue: 45
Pages: 6329-6342
•
•
•
•
•
Publication
26022372 | J:233930
First Author: Vinué Á
Year: 2015
Journal: Biochim Biophys Acta
Title: Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling.
Volume: 1852
Issue: 9
Pages: 1729-42
•
•
•
•
•
Publication
28620185 | J:323707
First Author: Xiang J
Year: 2017
Journal: Sci Rep
Title: c-Abl regulates gastrointestinal muscularis propria homeostasis via ERKs.
Volume: 7
Issue: 1
Pages: 3563
•
•
•
•
•
Publication
23637986 | J:200555
First Author: Ding BS
Year: 2013
Journal: PLoS One
Title: Prominin 1/CD133 endothelium sustains growth of proneural glioma.
Volume: 8
Issue: 4
Pages: e62150
•
•
•
•
•
Publication
12368906 | J:79704
First Author: Sharp R
Year: 2002
Journal: Nat Med
Title: Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis.
Volume: 8
Issue: 11
Pages: 1276-80
•
•
•
•
•
Publication
36113478 | J:332386
First Author: Chryplewicz A
Year: 2022
Journal: Cancer Cell
Title: Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Volume: 40
Issue: 10
Pages: 1111-1127.e9
•
•
•
•
•
Publication
22983396 | J:238049
First Author: Kwong LN
Year: 2012
Journal: Nat Med
Title: Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Volume: 18
Issue: 10
Pages: 1503-10
•
•
•
•
•
Publication
20682446 | J:163316
First Author: Pajcini KV
Year: 2010
Journal: Cell Stem Cell
Title: Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle.
Volume: 7
Issue: 2
Pages: 198-213
•
•
•
•
•
Publication
37169880 | J:357734
First Author: Kawamoto S
Year: 2023
Journal: Nat Cell Biol
Title: Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota.
Volume: 25
Issue: 6
Pages: 865-876
•
•
•
•
•
Publication
17291294 | J:216129
First Author: Yang D
Year: 2007
Journal: Aging Cell
Title: Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence.
Volume: 6
Issue: 2
Pages: 257-60
•
•
•
•
•
Publication
21062974 | J:166857
First Author: Takeuchi S
Year: 2010
Journal: Cancer Res
Title: Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
Volume: 70
Issue: 22
Pages: 9381-90
•
•
•
•
•
Publication
29234059 | J:257682
First Author: Okuma A
Year: 2017
Journal: Nat Commun
Title: p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis.
Volume: 8
Issue: 1
Pages: 2050
•
•
•
•
•
Publication
17924978 | J:131179
First Author: Kalamarides M
Year: 2008
Journal: Brain Pathol
Title: Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations.
Volume: 18
Issue: 1
Pages: 62-70
•
•
•
•
•
Publication
17699762 | J:124361
First Author: Chen YW
Year: 2007
Journal: Cancer Res
Title: Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells.
Volume: 67
Issue: 16
Pages: 7589-96
•
•
•
•
•
Publication
28278054 | J:274980
First Author: Scott A
Year: 2017
Journal: Cell Cycle
Title: p16 loss rescues functional decline of Brca1-deficient mammary stem cells.
Volume: 16
Issue: 8
Pages: 759-764
•
•
•
•
•
Publication
28108627 | J:239371
First Author: Liang C
Year: 2017
Journal: Mol Cancer Res
Title: Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Volume: 15
Issue: 2
Pages: 201-212
•
•
•
•
•
Publication
25176652 | J:233951
First Author: Muthalagu N
Year: 2014
Journal: Cell Rep
Title: BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.
Volume: 8
Issue: 5
Pages: 1347-53
•
•
•
•
•
Publication
37944881 | J:350360
 
First Author: Demby T
Year: 2024
Journal: Exp Neurol
Title: The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
Volume: 371
Pages: 114609
•
•
•
•
•
Publication
20118236 | J:161187
First Author: Whibley C
Year: 2010
Journal: J Biol Chem
Title: Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence.
Volume: 285
Issue: 15
Pages: 11326-35
•
•
•
•
•
Publication
21757616 | J:177091
First Author: Nishimoto N
Year: 2011
Journal: Blood
Title: Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF.
Volume: 118
Issue: 9
Pages: 2541-50
•
•
•
•
•
Publication
19147554 | J:143713
First Author: Seeley ES
Year: 2009
Journal: Cancer Res
Title: Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia.
Volume: 69
Issue: 2
Pages: 422-30
•
•
•
•
•
Publication
28240601 | J:243222
First Author: Li H
Year: 2017
Journal: J Clin Invest
Title: FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
Volume: 127
Issue: 4
Pages: 1241-1253
•
•
•
•
•
Publication
25437878 | J:220039
First Author: Pershing NL
Year: 2015
Journal: J Clin Invest
Title: Rare codons capacitate Kras-driven de novo tumorigenesis.
Volume: 125
Issue: 1
Pages: 222-33
•
•
•
•
•
Publication
30926782 | J:273283
First Author: Krimpenfort P
Year: 2019
Journal: Nat Commun
Title: A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis.
Volume: 10
Issue: 1
Pages: 1425
•
•
•
•
•
Publication
23858101 | J:234760
First Author: Dodd RD
Year: 2013
Journal: Mol Cancer Ther
Title: NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.
Volume: 12
Issue: 9
Pages: 1906-17
•
•
•
•
•
Publication
32109375 | J:285842
First Author: Salvador-Barbero B
Year: 2020
Journal: Cancer Cell
Title: CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
Volume: 37
Issue: 3
Pages: 340-353.e6
•
•
•
•
•
Publication
25799126 | J:231709
First Author: Zhang Q
Year: 2015
Journal: Nat Immunol
Title: The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation.
Volume: 16
Issue: 5
Pages: 458-66
•
•
•
•
•
Publication
33283624 | J:335419
First Author: Assenmacher CA
Year: 2021
Journal: J Histochem Cytochem
Title: Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.
Volume: 69
Issue: 3
Pages: 203-218
•
•
•
•
•
Publication
29643229 | J:352709
 
First Author: Neubert NJ
Year: 2018
Journal: Sci Transl Med
Title: T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.
Volume: 10
Issue: 436
•
•
•
•
•
Publication
23041550 | J:193650
First Author: Brown NE
Year: 2012
Journal: Cancer Res
Title: Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.
Volume: 72
Issue: 24
Pages: 6477-89
•
•
•
•
•
Publication
31981461 | J:286141
First Author: Yousefzadeh MJ
Year: 2020
Journal: Aging Cell
Title: Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.
Volume: 19
Issue: 3
Pages: e13094
•
•
•
•
•
Publication
28871086 | J:252245
First Author: Fuhrmann-Stroissnigg H
Year: 2017
Journal: Nat Commun
Title: Identification of HSP90 inhibitors as a novel class of senolytics.
Volume: 8
Issue: 1
Pages: 422
•
•
•
•
•
Publication
29747066 | J:273757
 
First Author: Robinson AR
Year: 2018
Journal: Redox Biol
Title: Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Volume: 17
Pages: 259-273
•
•
•
•
•
Publication
29133867 | J:255876
First Author: Gonçalves AF
Year: 2017
Journal: Nat Commun
Title: Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells.
Volume: 8
Issue: 1
Pages: 1466
•
•
•
•
•
Publication
23173060 | J:195459
First Author: Wehbe M
Year: 2012
Journal: PLoS One
Title: Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice.
Volume: 7
Issue: 11
Pages: e49419
•
•
•
•
•
Publication
20368423 | J:159287
First Author: Gleason G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety.
Volume: 107
Issue: 16
Pages: 7592-7
•
•
•
•
•
Publication
22275380 | J:182536
First Author: Zhang H
Year: 2012
Journal: Blood
Title: HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells.
Volume: 119
Issue: 11
Pages: 2595-607
•
•
•
•
•
Publication
20332237 | J:158892
First Author: Dineen SP
Year: 2010
Journal: Cancer Res
Title: Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer.
Volume: 70
Issue: 7
Pages: 2852-61
•
•
•
•
•
Publication
23407165 | J:195770
First Author: Guillaumond F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Volume: 110
Issue: 10
Pages: 3919-24
•
•
•
•
•
Publication
25675507 | J:220173
First Author: Guillaumond F
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Volume: 112
Issue: 8
Pages: 2473-8
•
•
•
•
•
Publication
19118015 | J:143028
First Author: Menon R
Year: 2009
Journal: Cancer Res
Title: Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer.
Volume: 69
Issue: 1
Pages: 300-9
•
•
•
•
•
Publication
26404002 | J:226774
First Author: Loncle C
Year: 2015
Journal: Cancer Res
Title: IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Volume: 75
Issue: 22
Pages: 4852-62
•
•
•
•
•
Publication
19477428 | J:149663
First Author: Singh A
Year: 2009
Journal: Cancer Cell
Title: A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.
Volume: 15
Issue: 6
Pages: 489-500
•
•
•
•
•
Publication
21673986 | J:174139
First Author: Wang Z
Year: 2011
Journal: PLoS One
Title: Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
Volume: 6
Issue: 6
Pages: e20537
•
•
•
•
•
Publication
19629168 | J:151781
First Author: Vincent DF
Year: 2009
Journal: PLoS Genet
Title: Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
Volume: 5
Issue: 7
Pages: e1000575
•
•
•
•
•
Publication
18547137 | J:139894
First Author: Faca VM
Year: 2008
Journal: PLoS Med
Title: A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
Volume: 5
Issue: 6
Pages: e123
•
•
•
•
•
Publication
21589862 | J:172643
First Author: Kelly-Spratt KS
Year: 2011
Journal: PLoS One
Title: Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Volume: 6
Issue: 5
Pages: e19721
•
•
•
•
•
Publication
27701147 | J:239623
First Author: Leca J
Year: 2016
Journal: J Clin Invest
Title: Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.
Volume: 126
Issue: 11
Pages: 4140-4156
•
•
•
•
•
Publication
31699795 | J:284231
First Author: Dominguez CX
Year: 2020
Journal: Cancer Discov
Title: Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Volume: 10
Issue: 2
Pages: 232-253
•
•
•
•
•
Publication
35307861 | J:332833
First Author: Gouirand V
Year: 2022
Journal: EMBO J
Title: Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.
Volume: 41
Issue: 9
Pages: e110466
•
•
•
•
•
Publication
27889388 | J:256737
First Author: Berry DC
Year: 2017
Journal: Cell Metab
Title: Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans.
Volume: 25
Issue: 1
Pages: 166-181
•
•
•
•
•
Publication
34737348 | J:312881
First Author: Ueda S
Year: 2021
Journal: Sci Rep
Title: TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction.
Volume: 11
Issue: 1
Pages: 21643
•
•
•
•
•
Publication
28368403 | J:248159
First Author: Shin CH
Year: 2017
Journal: Oncogene
Title: HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss.
Volume: 36
Issue: 32
Pages: 4610-4618
•
•
•
•
•
Publication
20008304 | J:157729
First Author: Medyouf H
Year: 2010
Journal: Blood
Title: Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
Volume: 115
Issue: 6
Pages: 1175-84
•
•
•
•
•
Publication
36868238 | J:334507
First Author: Ji ML
Year: 2023
Journal: Am J Hum Genet
Title: Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis.
Volume: 110
Issue: 4
Pages: 606-624
•
•
•
•
•
Publication
16837500 | J:114158
First Author: Ohtsuka Y
Year: 2006
Journal: Eur Respir J
Title: Genetic linkage analysis of pulmonary fibrotic response to silica in mice.
Volume: 28
Issue: 5
Pages: 1013-9
•
•
•
•
•
Publication
33028660 | J:303971
First Author: Ohkawa Y
Year: 2021
Journal: Mol Cancer Res
Title: Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM.
Volume: 19
Issue: 1
Pages: 150-161
•
•
•
•
•
Publication
24307508 | J:216556
First Author: Perez-Campo FM
Year: 2014
Journal: Stem Cells
Title: MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells.
Volume: 32
Issue: 6
Pages: 1591-601
•
•
•
•
•
Publication
33758201 | J:346267
First Author: Liu X
Year: 2021
Journal: Nat Commun
Title: Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis.
Volume: 12
Issue: 1
Pages: 1832
•
•
•
•
•
Publication
30671114 | J:281699
First Author: Park BM
Year: 2018
Journal: Lab Anim Res
Title: Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing.
Volume: 34
Issue: 4
Pages: 264-269
•
•
•
•
•
Publication
31427681 | J:284820
First Author: Koyano T
Year: 2019
Journal: Sci Rep
Title: The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis.
Volume: 9
Issue: 1
Pages: 12059
•
•
•
•
•
Publication
11718560 | J:72910
First Author: Bothner B
Year: 2001
Journal: J Mol Biol
Title: Defining the molecular basis of Arf and Hdm2 interactions.
Volume: 314
Issue: 2
Pages: 263-77
•
•
•
•
•
Publication
21555589 | J:171888
First Author: Li DQ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis.
Volume: 108
Issue: 21
Pages: 8791-6
•
•
•
•
•
Publication
11751403 | J:73359
First Author: Gadd M
Year: 2001
Journal: Cancer Res
Title: Regulation of cyclin D1 and p16(INK4A) is critical for growth arrest during mammary involution.
Volume: 61
Issue: 24
Pages: 8811-9
•
•
•
•
•
Publication
9061010 | J:38653
First Author: Pines J
Year: 1997
Journal: Biochim Biophys Acta
Title: Cyclin-dependent kinase inhibitors: the age of crystals.
Volume: 1332
Issue: 1
Pages: M39-42
•
•
•
•
•
Publication
14555993 | J:95343
First Author: Schreiner B
Year: 2003
Journal: Oncogene
Title: Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci.
Volume: 22
Issue: 43
Pages: 6802-9
•
•
•
•
•
Publication
19331830 | J:148177
First Author: di Tommaso A
Year: 2009
Journal: Exp Cell Res
Title: Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities.
Volume: 315
Issue: 7
Pages: 1326-35
•
•
•
•
•
Publication
19462008 | J:148837
First Author: Agherbi H
Year: 2009
Journal: PLoS One
Title: Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence.
Volume: 4
Issue: 5
Pages: e5622
•
•
•
•
•
Publication
21383063 | J:172816
First Author: Ginjala V
Year: 2011
Journal: Mol Cell Biol
Title: BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.
Volume: 31
Issue: 10
Pages: 1972-82
•
•
•
•
•
Publication
21730286 | J:175078
First Author: Mei J
Year: 2011
Journal: Mol Cell Biol
Title: MicroRNA-146a inhibits glioma development by targeting Notch1.
Volume: 31
Issue: 17
Pages: 3584-92
•
•
•
•
•
Publication
23334668 | J:198063
First Author: Holmfeldt L
Year: 2013
Journal: Nat Genet
Title: The genomic landscape of hypodiploid acute lymphoblastic leukemia.
Volume: 45
Issue: 3
Pages: 242-52
•
•
•
•
•
Publication
24216481 | J:204179
First Author: Zhou JX
Year: 2013
Journal: J Clin Invest
Title: Combined modulation of polycomb and trithorax genes rejuvenates β cell replication.
Volume: 123
Issue: 11
Pages: 4849-58
•
•
•
•
•
Publication
23826727 | J:214884
First Author: Zeng N
Year: 2013
Journal: Aging Cell
Title: PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.
Volume: 12
Issue: 6
Pages: 1000-11
•
•
•
•
•
Publication
26321221 | J:225960
First Author: Churchman ML
Year: 2015
Journal: Cancer Cell
Title: Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.
Volume: 28
Issue: 3
Pages: 343-56
•
•
•
•
•
Publication
28346462 | J:242316
First Author: De Jaime-Soguero A
Year: 2017
Journal: PLoS Genet
Title: Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus.
Volume: 13
Issue: 3
Pages: e1006682
•
•
•
•
•
Publication
24950189 | J:354523
First Author: Yoshida Y
Year: 2014
Journal: PLoS One
Title: Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway.
Volume: 9
Issue: 6
Pages: e100359
•
•
•
•
•
Publication
24162189 | J:316606
 
First Author: Carlos AR
Year: 2013
Journal: Nat Commun
Title: ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets.
Volume: 4
Pages: 2697
•
•
•
•
•
Publication
25784651 | J:312834
First Author: Yetil A
Year: 2015
Journal: Oncotarget
Title: p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.
Volume: 6
Issue: 6
Pages: 3563-77
•
•
•
•
•
Publication
29440280 | J:311854
First Author: Luo C
Year: 2018
Journal: J Am Soc Nephrol
Title: Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells.
Volume: 29
Issue: 4
Pages: 1238-1256
•
•
•
•
•
Publication
36457728 | J:332057
 
First Author: Liang Y
Year: 2022
Journal: Oxid Med Cell Longev
Title: p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Volume: 2022
Pages: 3415528
•
•
•
•
•
Publication
19380490 | J:149898
First Author: Sashida G
Year: 2009
Journal: Mol Cell Biol
Title: ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.
Volume: 29
Issue: 13
Pages: 3687-99
•
•
•
•
•
Publication
7651726 | J:28319
First Author: Quelle DE
Year: 1995
Journal: Oncogene
Title: Cloning and characterization of murine p16INK4a and p15INK4b genes.
Volume: 11
Issue: 4
Pages: 635-45
•
•
•
•
•
Publication
9482902 | J:46172
First Author: Zhang S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.
Volume: 95
Issue: 5
Pages: 2429-34
•
•
•
•
•
Publication
22028794 | J:179766
First Author: Kajiro M
Year: 2011
Journal: PLoS One
Title: The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.
Volume: 6
Issue: 10
Pages: e25871
•
•
•
•
•
Publication
37092554 | J:346273
 
First Author: Sawaki D
Year: 2023
Journal: JCI Insight
Title: Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction.
Volume: 8
Issue: 8
•
•
•
•
•
Publication
22367038 | J:182722
First Author: Debbache J
Year: 2012
Journal: Genetics
Title: In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor.
Volume: 191
Issue: 1
Pages: 133-44
•
•
•
•
•
Publication
29136505 | J:249173
First Author: Bejarano L
Year: 2017
Journal: Cancer Cell
Title: Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts.
Volume: 32
Issue: 5
Pages: 590-607.e4
•
•
•
•
•
Publication
18411339 | J:136278
First Author: Yamashita M
Year: 2008
Journal: J Exp Med
Title: Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene.
Volume: 205
Issue: 5
Pages: 1109-20
•
•
•
•
•
Publication
22718909 | J:199702
First Author: Sitaram A
Year: 2012
Journal: Mol Biol Cell
Title: Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.
Volume: 23
Issue: 16
Pages: 3178-92
•
•
•
•
•
Publication
31189923 | J:283540
First Author: Zhu P
Year: 2019
Journal: Nat Commun
Title: The transcription factor Slug represses p16Ink4a and regulates murine muscle stem cell aging.
Volume: 10
Issue: 1
Pages: 2568
•
•
•
•
•
Publication
16914517 | J:117973
First Author: Hume AN
Year: 2006
Journal: Mol Biol Cell
Title: A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes.
Volume: 17
Issue: 11
Pages: 4720-35
•
•
•
•
•
Publication
26365380 | J:228087
First Author: Skowronska-Krawczyk D
Year: 2015
Journal: Mol Cell
Title: P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.
Volume: 59
Issue: 6
Pages: 931-40
•
•
•
•
•
Publication
17374722 | J:120126
First Author: Scott CL
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role of the chromobox protein CBX7 in lymphomagenesis.
Volume: 104
Issue: 13
Pages: 5389-94
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom