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Search results 1001 to 1100 out of 1202 for E2f1

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Type Details Score
Publication
12934101 | J:85354
First Author: Berton TR
Year: 2003
Journal: Oncogene
Title: Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
Volume: 22
Issue: 35
Pages: 5415-26
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Publication
15220935 | J:91632
First Author: Calvisi DF
Year: 2004
Journal: Lab Invest
Title: Disregulation of E-cadherin in transgenic mouse models of liver cancer.
Volume: 84
Issue: 9
Pages: 1137-47
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Protein
Q3UFM7
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Protein Domain
IPR015030 | RB_C
Type: Domain
Description: The RB C-terminal domain is required for high-affinity binding to E2F-DP complexes and for maximal repression of E2F-responsive promoters, thereby acting as a growth suppressor by blocking the G1-S transition of the cell cycle. This domain has a strand-loop-helix structure, which directly interacts with both E2F1 and DP1, followed by a tail segment that lacks regular secondary structure [].
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HT Experiment
GSE182721 | Lats1/2 control TGF-beta directed EMT in the dorsal cranial neuroepithelium through YAP regulation
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Brca1/Brca1<+> Tg(KRT5-E2F1)2Dgj/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Publication
15565109 | J:95489
First Author: Lee JS
Year: 2004
Journal: Nat Genet
Title: Application of comparative functional genomics to identify best-fit mouse models to study human cancer.
Volume: 36
Issue: 12
Pages: 1306-11
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Protein Domain
IPR033576 | CDCA7
Type: Family
Description: Cell division cycle-associated protein 7 (CDCA7/JPO1) is a transcription regulator whose expression is activated by c-Myc and by E2F1 []. CDCA7 can associate with Myc in a phosphorylation-dependent manner. CDCA7 phosphorylation by AKT leads to loss of its association with Myc []. This interaction affects Myc-dependent apoptosis and transformation [, , ]. CDCA7 has also been identified as a Notch target involved in hematopoietic stem cell emergence [].
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Publication
15885355 | J:101128
First Author: Calvisi DF
Year: 2005
Journal: J Hepatol
Title: Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer.
Volume: 42
Issue: 6
Pages: 842-9
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(KRT5-E2F1)2Dgj/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1 E2f3/E2f3
Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N * NIH Black Swiss
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tmem163/?
Background: involves: 129P2/OlaHsd * FVB * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gtf2ird1/Gtf2ird1<+> Tg(Alb-E2F1)8Sst/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Publication
16580749 | -
First Author: Goto Y
Year: 2006
Journal: Biochim Biophys Acta
Title: JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity.
Volume: 1759
Issue: 1-2
Pages: 60-8
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Protein
A2AR39
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Publication
23166294 | J:194226
First Author: Gill RM
Year: 2013
Journal: Mol Cell Biol
Title: The MYC-associated protein CDCA7 is phosphorylated by AKT to regulate MYC-dependent apoptosis and transformation.
Volume: 33
Issue: 3
Pages: 498-513
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Publication
11598121 | -
First Author: Prescott JE
Year: 2001
Journal: J Biol Chem
Title: A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformation.
Volume: 276
Issue: 51
Pages: 48276-84
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Publication
25385755 | -
First Author: Guiu J
Year: 2014
Journal: J Exp Med
Title: Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence.
Volume: 211
Issue: 12
Pages: 2411-23
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HT Experiment
E-GEOD-79451 | Gene expression in mouse thyrotrope adenoma: transcription elongation factor stimulates proliferation
Series Id: GSE79451
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-13753 | Transcription profiling of mouse placentas from wild-type and Rb -/- knock-out mice and embryonic day 11.5 placentas from wild-type and Rb -/-;E2f4 -/- double knock-outs reveals E2F4 cooperates with pRB in the development of extra-embryonic, not embryonic, tissues
Series Id: GSE13753
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
15131798 | J:90164
First Author: Calvisi DF
Year: 2004
Journal: Gastroenterology
Title: Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice.
Volume: 126
Issue: 5
Pages: 1374-86
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Publication
14684733 | J:88864
First Author: Scheijen B
Year: 2004
Journal: J Biol Chem
Title: High incidence of thymic epithelial tumors in E2F2 transgenic mice.
Volume: 279
Issue: 11
Pages: 10476-83
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(KRT5-cre)5132Jlj/? Tg(KRT5-E2F1)2Dgj/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
1835093 | -
First Author: Webster LC
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.
Volume: 88
Issue: 22
Pages: 9989-93
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Publication
1316611 | -
First Author: Chellappan S
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Volume: 89
Issue: 10
Pages: 4549-53
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Publication
22718244 | -
First Author: Bellacchio E
Year: 2013
Journal: J Cell Physiol
Title: Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.
Volume: 228
Issue: 2
Pages: 285-91
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Protein Domain
IPR014410 | Aden_E1A
Type: Family
Description: This group represents adenoviral early E1A proteins. The E1A protein is responsible for the transcriptional activation of the early genes with in the viral genome at the start of the infection process as well as some cellular genes [].E1A disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle []. It also induces the disassembly of the E2F1 transcription factors from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes []. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. The stimulation of the progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.
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Publication
15994933 | J:99527
First Author: Huang A
Year: 2005
Journal: Cancer Res
Title: Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells.
Volume: 65
Issue: 13
Pages: 5607-19
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Protein
Q9D0M2
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
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Publication
11230146 | J:67783
First Author: Ziebold U
Year: 2001
Journal: Genes Dev
Title: E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos.
Volume: 15
Issue: 4
Pages: 386-91
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Publication
23796898 | J:199460
First Author: Ammirante M
Year: 2013
Journal: Genes Dev
Title: An IKKα-E2F1-BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence.
Volume: 27
Issue: 13
Pages: 1435-40
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Publication
25117714 | J:214594
First Author: Ozawa T
Year: 2014
Journal: Cancer Cell
Title: Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Volume: 26
Issue: 2
Pages: 288-300
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Publication
20850540 | J:170790
First Author: Iakova P
Year: 2011
Journal: Semin Cancer Biol
Title: Intracellular signaling and hepatocellular carcinoma.
Volume: 21
Issue: 1
Pages: 28-34
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Publication
22174740 | -
First Author: Rodriguez-Jato S
Year: 2011
Journal: PLoS One
Title: Drosophila melanogaster dHCF interacts with both PcG and TrxG epigenetic regulators.
Volume: 6
Issue: 12
Pages: e27479
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Publication
18414036 | J:182490
First Author: Dubrez-Daloz L
Year: 2008
Journal: Cell Cycle
Title: IAPs: more than just inhibitors of apoptosis proteins.
Volume: 7
Issue: 8
Pages: 1036-46
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Protein
F7BQL8
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Publication
10629049 | -
First Author: Mahajan SS
Year: 2000
Journal: Mol Cell Biol
Title: Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.
Volume: 20
Issue: 3
Pages: 919-28
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Publication
14532282 | J:87274
First Author: Luciano RL
Year: 2003
Journal: J Biol Chem
Title: HCF-1 functions as a coactivator for the zinc finger protein Krox20.
Volume: 278
Issue: 51
Pages: 51116-24
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Publication
10675337 | -
First Author: Vogel JL
Year: 2000
Journal: EMBO J
Title: The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.
Volume: 19
Issue: 4
Pages: 683-90
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Publication
12244100 | -
First Author: Piluso D
Year: 2002
Journal: J Biol Chem
Title: Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.
Volume: 277
Issue: 48
Pages: 46799-808
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Publication
10920196 | -
First Author: Vogel JL
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Autocatalytic proteolysis of the transcription factor-coactivator C1 (HCF): a potential role for proteolytic regulation of coactivator function.
Volume: 97
Issue: 17
Pages: 9425-30
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Publication
16624878 | -
First Author: Vogel JL
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.
Volume: 103
Issue: 18
Pages: 6817-22
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Publication
31049581 | -
First Author: Gudkova D
Year: 2019
Journal: Nucleic Acids Res
Title: HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs.
Volume: 47
Issue: 11
Pages: 5792-5808
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Publication
19153467 | -
First Author: Kulathila R
Year: 2009
Journal: Acta Crystallogr D Biol Crystallogr
Title: The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
Volume: 65
Issue: Pt 1
Pages: 58-66
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Publication
22021857 | -
First Author: Dueber EC
Year: 2011
Journal: Science
Title: Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.
Volume: 334
Issue: 6054
Pages: 376-80
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Publication
21447281 | -
First Author: Damgaard RB
Year: 2011
Journal: Discov Med
Title: Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity.
Volume: 11
Issue: 58
Pages: 221-31
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Publication
12609738 | -
First Author: Izeta A
Year: 2003
Journal: Gene
Title: Primary structure and compartmentalization of Drosophila melanogaster host cell factor.
Volume: 305
Issue: 2
Pages: 175-83
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Publication
2568582 | -
First Author: Sabina RL
Year: 1989
Journal: Mol Cell Biol
Title: Expression of three stage-specific transcripts of AMP deaminase during myogenesis.
Volume: 9
Issue: 5
Pages: 2244-6
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Protein Domain
IPR043536 | HCF1/2
Type: Family
Description: This entry includes Host cell factor 1 (HCF1) and Host cell factor 2 (HCF2) from humans. They contain an N-terminal kelch domain and a C-terminal FnIII domain. However, HCF2 is smaller than HCF-1, lacking the complete central region including the HCF1 specific repeats and as a result is not subject to proteolytic processing []. This entry also includes their Drosophila melanogaster homologue, dHCF, which is involved in both activation and repression of transcription during fly development []. Host cell factor homologue hcf-1 from C. elegans controls the cell cycle through mitotic histone phosphorylation modulation and negatively regulates responses to environmental stresses [].HCF1 is associated with the activation and repression of gene expression. It is brought to specific promoters by association with DNA-sequence-specific transcription factors such as Sp1, GABP, YY1, Ronin/THAP11, and E2F1 and E2F4 []. HCFC1 recruits and is a part of several different complexes, including the SET1 histone methyltransferase complex (transcription activation), the SIN3 histone deacetylase complex (transcription repression) [], the THAP1/THAP3-HCFC1-OGT complex (required for the regulation of the transcriptional activity of RRM1) [], and the NSL complex (acetylation of nucleosomal histone H4) [].HCF2 is involved in activation of differentiation and morphogenesis gene expression programs, and in parallel in inhibition of cellular growth and metabolism [].
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Protein Domain
IPR037854 | HCF1
Type: Family
Description: Host cell factor 1 (HCFC1) is associated with the activation and repression of gene expression. It is brought to specific promoters by association with DNA-sequence-specific transcription factors such as Sp1, GABP, YY1, Ronin/THAP11, and E2F1 and E2F4 []. HCFC1 recruits and is a part of several different complexes, including the SET1 histone methyltransferase complex (transcription activation), the SIN3 histone deacetylase complex (transcription repression) [], the THAP1/THAP3-HCFC1-OGT complex (required for the regulation of the transcriptional activity of RRM1) [], and the NSL complex (acetylation of nucleosomal histone H4) []. This entry includes mammalian HCFC1 and the Drosophila homologue, dHCF. They undergo a process of proteolytic maturation to produce a heterodimeric complex of HCF-N and HCF-C subunits, by different enzymes, O-GlcNAc transferase and taspase1, respectively [, ]. They share a Kelch domain, regions biased for basic (Basic) or acidic (Acidic) amino acids, fibronectin type 3 repeats, and a nuclear localization signal [].During human herpes simplex virus infection, HCFC1 forms a multiprotein-DNA complex enabling transcription of the virus's early genes []. It is also a co-activator of EGR2/Krox20 []and the GA-binding protein GABP2 [], and represses ZBTB17/Miz-1 [].
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Protein Domain
IPR041933 | BIRC2/BIRC3_UBA
Type: Domain
Description: The entry represents the UBA domain found in c-IAPs, including BIRC2 (also known as C-IAP1) and BIRC3 (also known as C-IAP2). c-IAPs function as ubiquitin E3 ligases that mediate the ubiquitination of the substrates involved in apoptosis, nuclear factor-kappaB (NF-kappaB) signaling, and oncogenesis [, ]. Unlike other apoptosis proteins such as XIAP, c-IAPs exhibit minimal binding to caspases and may not play an important role in the inhibition of these proteases. c-IAP1 is a potent regulator of the tumor necrosis factor (TNF) receptor family and NF-kappaB signaling pathways in the cytoplasm. It can also regulate E2F1 transcription factor-mediated control of cyclin transcription in the nucleus []. c-IAP2 also influences ubiquitin-dependent pathways that modulate innate immune signalling by activation of NF-kappaB []. c-IAPs contain three N-terminal baculoviral IAP repeat (BIR) domains that enable interactions with proteins, a ubiquitin-association (UBA) domain that is responsible for the binding of polyubiquitin (polyUb), a caspase activation and recruitment domain (CARD) that serves as a protein interaction surface, and a RING domain at the carboxyl terminus that is required for ubiquitin ligase activity [, ].
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Protein Domain
IPR040221 | CDCA7/CDA7L
Type: Family
Description: This entry includes CDCA7 and CDA7L.Cell division cycle-associated protein 7 (CDCA7/JPO1) is a transcription regulator whose expression is activated by c-Myc and by E2F1 []. CDCA7 can associate with Myc in a phosphorylation-dependent manner. CDCA7 phosphorylation by AKT leads to loss of its association with Myc []. This interaction affects Myc-dependent apoptosis and transformation [, , ]. CDCA7 has also been identified as a Notch target involved in hematopoietic stem cell emergence [].Cell division cycle-associated 7-like protein (CDCA7L/JPO2/R1) is closely related to CDCA7/JPO1; and like CDCA7, it plays a role in transcriptional regulation and interacts with c-Myc []. JPO2 overexpression induces metastasis in medulloblastoma []. JPO2 can interact directly and dynamically with chromatin, the dynamics of JPO2 chromatin binding being decelerated upon interaction with LEDGF/p75, which binds and tethers JPO2 to chromatin [, ].JPO2 inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter []. JPO2 and MAOA act upstream of cyclin D1 and E2F1, and are involved in apoptotic signalling pathways [].
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Publication
18194653 | J:131292
First Author: Li J
Year: 2008
Journal: Dev Cell
Title: Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
Volume: 14
Issue: 1
Pages: 62-75
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Publication
11350120 | J:69581
First Author: Wang A
Year: 2001
Journal: Genomics
Title: Molecular cloning and characterization of a novel mouse epidermal differentiation gene and its promoter.
Volume: 73
Issue: 3
Pages: 284-90
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Publication
15563841 | J:94137
First Author: Evrard C
Year: 2004
Journal: Gene
Title: Functional analysis of the NPDC-1 gene.
Volume: 343
Issue: 1
Pages: 153-63
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Publication
23443259 | J:207261
 
First Author: Hou ST
Year: 2013
Journal: Sci Rep
Title: Collapsin response mediator protein 3 deacetylates histone H4 to mediate nuclear condensation and neuronal death.
Volume: 3
Pages: 1350
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Publication
12588846 | J:81580
First Author: Kohn MJ
Year: 2003
Journal: Development
Title: Dp1 is required for extra-embryonic development.
Volume: 130
Issue: 7
Pages: 1295-305
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Publication
32968066 | J:303351
First Author: Oh J
Year: 2020
Journal: Nat Commun
Title: Macrophage secretion of miR-106b-5p causes renin-dependent hypertension.
Volume: 11
Issue: 1
Pages: 4798
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Publication
22985930 | J:192757
First Author: Dingar D
Year: 2012
Journal: J Mol Cell Cardiol
Title: Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes.
Volume: 53
Issue: 6
Pages: 820-8
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Publication
26459601 | J:237592
First Author: Zou Z
Year: 2015
Journal: J Cell Biol
Title: mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.
Volume: 211
Issue: 1
Pages: 105-22
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Publication
28723554 | J:260578
First Author: Murata K
Year: 2017
Journal: Immunity
Title: Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.
Volume: 47
Issue: 1
Pages: 66-79.e5
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Publication
29444430 | J:271068
First Author: Böni-Schnetzler M
Year: 2018
Journal: Cell Rep
Title: β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion.
Volume: 22
Issue: 7
Pages: 1774-1786
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Publication
27991597 | J:243450
 
First Author: Jablonska B
Year: 2016
Journal: Nat Commun
Title: Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.
Volume: 7
Pages: 13866
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Publication
16213226 | J:129675
First Author: Abella A
Year: 2005
Journal: Cell Metab
Title: Cdk4 promotes adipogenesis through PPARgamma activation.
Volume: 2
Issue: 4
Pages: 239-49
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Publication
19917728 | J:156401
First Author: Martinez LA
Year: 2010
Journal: Mol Cell Biol
Title: E2F3 is a mediator of DNA damage-induced apoptosis.
Volume: 30
Issue: 2
Pages: 524-36
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Publication
24728959 | J:211181
First Author: Federico A
Year: 2014
Journal: Biol Open
Title: Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype.
Volume: 3
Issue: 5
Pages: 372-8
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Publication
19249677 | J:145939
First Author: Ianari A
Year: 2009
Journal: Cancer Cell
Title: Proapoptotic function of the retinoblastoma tumor suppressor protein.
Volume: 15
Issue: 3
Pages: 184-94
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Publication
26724859 | J:232734
First Author: Chen CL
Year: 2016
Journal: Cell Metab
Title: NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism.
Volume: 23
Issue: 1
Pages: 206-19
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Publication
10708476 | J:61215
First Author: Johnson DG
Year: 2000
Journal: Mol Carcinog
Title: The paradox of E2F1: oncogene and tumor suppressor gene.
Volume: 27
Issue: 3
Pages: 151-7
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Publication
9556576 | J:47422
First Author: Gopalkrishnan RV
Year: 1998
Journal: J Biol Chem
Title: The p53 tumor suppressor inhibits transcription of the TATA-less mouse DP1 promoter.
Volume: 273
Issue: 18
Pages: 10972-8
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Publication
16969098 | J:115502
First Author: Fedele M
Year: 2006
Journal: Cell Cycle
Title: Critical role of the HMGA2 gene in pituitary adenomas.
Volume: 5
Issue: 18
Pages: 2045-8
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Publication
22431589 | J:182657
First Author: Suh SS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.
Volume: 109
Issue: 14
Pages: 5316-21
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Publication
25284223 | J:215524
First Author: Wei N
Year: 2014
Journal: Mol Cell
Title: Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.
Volume: 56
Issue: 2
Pages: 323-32
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Publication
19893569 | J:259107
First Author: Wu ZL
Year: 2010
Journal: Cell Death Differ
Title: Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression.
Volume: 17
Issue: 5
Pages: 801-10
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Publication
31262817 | J:278407
First Author: Wang C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Long noncoding RNA EMS connects c-Myc to cell cycle control and tumorigenesis.
Volume: 116
Issue: 29
Pages: 14620-14629
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Publication
33462236 | J:300910
First Author: Larrue C
Year: 2021
Journal: Nat Commun
Title: Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells.
Volume: 12
Issue: 1
Pages: 422
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Publication
12670868 | -
First Author: Wysocka J
Year: 2003
Journal: Genes Dev
Title: Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
Volume: 17
Issue: 7
Pages: 896-911
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Publication
16829576 | J:111804
First Author: Ou XM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway.
Volume: 103
Issue: 29
Pages: 10923-8
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Protein
Q922M5
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
H3BJV7
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: true
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Protein
Q62017
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
H3BJN2
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
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Publication
16360038 | -
First Author: Rubin SM
Year: 2005
Journal: Cell
Title: Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Volume: 123
Issue: 6
Pages: 1093-106
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Publication
15654081 | -
First Author: Chen K
Year: 2005
Journal: J Biol Chem
Title: R1, a novel repressor of the human monoamine oxidase A.
Volume: 280
Issue: 12
Pages: 11552-9
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Publication
27013196 | -
First Author: Chan TS
Year: 2016
Journal: Cancer Res
Title: JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.
Volume: 76
Issue: 9
Pages: 2802-12
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Publication
24634210 | -
First Author: Hendrix J
Year: 2014
Journal: J Biol Chem
Title: Dynamics of the ternary complex formed by c-Myc interactor JPO2, transcriptional co-activator LEDGF/p75, and chromatin.
Volume: 289
Issue: 18
Pages: 12494-506
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Publication
16735438 | -
First Author: Maertens GN
Year: 2006
Journal: J Cell Sci
Title: Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin.
Volume: 119
Issue: Pt 12
Pages: 2563-71
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Publication
16616919 | J:111352
First Author: Yoshimoto T
Year: 2006
Journal: Exp Cell Res
Title: The arginine methyltransferase PRMT2 binds RB and regulates E2F function.
Volume: 312
Issue: 11
Pages: 2040-53
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Publication
10915798 | J:63800
First Author: Taniguchi N
Year: 2000
Journal: J Biol Chem
Title: The postmitotic growth suppressor necdin interacts with a calcium-binding protein (NEFA) in neuronal cytoplasm.
Volume: 275
Issue: 41
Pages: 31674-81
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Publication
10965153 | J:74072
First Author: Niinobe M
Year: 2000
Journal: Dev Neurosci
Title: Cellular and subcellular localization of necdin in fetal and adult mouse brain.
Volume: 22
Issue: 4
Pages: 310-9
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Publication
30115652 | J:265931
First Author: Sanchez-Parra C
Year: 2018
Journal: Diabetes
Title: Contribution of the Long Noncoding RNA H19 to β-Cell Mass Expansion in Neonatal and Adult Rodents.
Volume: 67
Issue: 11
Pages: 2254-2267
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Publication
27793841 | J:237995
First Author: Kang DW
Year: 2017
Journal: Cancer Res
Title: Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
Volume: 77
Issue: 1
Pages: 142-152
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Publication
37591449 | J:340643
 
First Author: Zhang S
Year: 2023
Journal: Biochem Pharmacol
Title: Hydrogen sulfide promoted retinoic acid-related orphan receptor α transcription to alleviate diabetic cardiomyopathy.
Volume: 215
Pages: 115748
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Publication
23149912 | J:194107
First Author: Lee JH
Year: 2013
Journal: Cancer Res
Title: DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells.
Volume: 73
Issue: 2
Pages: 785-91
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Publication
20080939 | J:158372
First Author: Almeida MQ
Year: 2010
Journal: Hum Mol Genet
Title: Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.
Volume: 19
Issue: 8
Pages: 1387-98
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Publication
11731416 | J:73154
First Author: Guo Z
Year: 2001
Journal: Cancer Res
Title: Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.
Volume: 61
Issue: 23
Pages: 8395-400
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Publication
17173070 | J:122861
First Author: Prost S
Year: 2007
Journal: Oncogene
Title: E2F regulates DDB2: consequences for DNA repair in Rb-deficient cells.
Volume: 26
Issue: 24
Pages: 3572-81
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Publication
22331469 | J:183798
First Author: Hasegawa N
Year: 2012
Journal: Mol Cell Biol
Title: Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells.
Volume: 32
Issue: 8
Pages: 1483-95
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Publication
21131441 | J:186820
First Author: Yang IV
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: Novel regulators of the systemic response to lipopolysaccharide.
Volume: 45
Issue: 2
Pages: 393-402
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Publication
16912189 | J:113386
First Author: Hobbs CA
Year: 2006
Journal: Cancer Res
Title: Tip60 protein isoforms and altered function in skin and tumors that overexpress ornithine decarboxylase.
Volume: 66
Issue: 16
Pages: 8116-22
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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