Type |
Details |
Score |
Publication |
First Author: |
Kaphzan H |
Year: |
2012 |
Journal: |
Biol Psychiatry |
Title: |
Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors. |
Volume: |
72 |
Issue: |
3 |
Pages: |
182-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancuso R |
Year: |
2016 |
Journal: |
Neurobiol Dis |
Title: |
Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1(G93A) ALS mice and after partial muscle denervation. |
Volume: |
95 |
|
Pages: |
168-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dreymueller D |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes. |
Volume: |
192 |
Issue: |
2 |
Pages: |
722-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Tuathaigh CM |
Year: |
2017 |
Journal: |
Schizophr Bull |
Title: |
Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1. |
Volume: |
43 |
Issue: |
1 |
Pages: |
214-225 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamura H |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Processing of neuregulin-1 by neuropsin regulates GABAergic neuron to control neural plasticity of the mouse hippocampus. |
Volume: |
32 |
Issue: |
37 |
Pages: |
12657-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang GX |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. |
Volume: |
20 |
Issue: |
12 |
Pages: |
1436-1443 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paramo B |
Year: |
2021 |
Journal: |
eNeuro |
Title: |
Neuregulin-4 Is Required for Maintaining Soma Size of Pyramidal Neurons in the Motor Cortex. |
Volume: |
8 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Navarro-Gonzalez C |
Year: |
2021 |
Journal: |
Neurobiol Dis |
Title: |
Nrg1 haploinsufficiency alters inhibitory cortical circuits. |
Volume: |
157 |
|
Pages: |
105442 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rajebhosale P |
Year: |
2024 |
Journal: |
J Neurosci |
Title: |
Neuregulin1 Nuclear Signaling Influences Adult Neurogenesis and Regulates a Schizophrenia Susceptibility Gene Network within the Mouse Dentate Gyrus. |
Volume: |
44 |
Issue: |
43 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hao J |
Year: |
2014 |
Journal: |
Biochem J |
Title: |
Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors. |
Volume: |
458 |
Issue: |
2 |
Pages: |
335-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lemmens K |
Year: |
2011 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. |
Volume: |
300 |
Issue: |
3 |
Pages: |
H931-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jo SA |
Year: |
1995 |
Journal: |
Nature |
Title: |
Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression. |
Volume: |
373 |
Issue: |
6510 |
Pages: |
158-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hatakeyama J |
Year: |
2016 |
Journal: |
Sci Signal |
Title: |
The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3. |
Volume: |
9 |
Issue: |
434 |
Pages: |
ra65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murphy P |
Year: |
1996 |
Journal: |
Development |
Title: |
The regulation of Krox-20 expression reveals important steps in the control of peripheral glial cell development. |
Volume: |
122 |
Issue: |
9 |
Pages: |
2847-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang YZ |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95. |
Volume: |
276 |
Issue: |
22 |
Pages: |
19318-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Z |
Year: |
2004 |
Journal: |
Exp Cell Res |
Title: |
Lysophosphatidic acid regulates murine blastocyst development by transactivation of receptors for heparin-binding EGF-like growth factor. |
Volume: |
296 |
Issue: |
2 |
Pages: |
317-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Strachan RT |
Year: |
2010 |
Journal: |
Biochemistry |
Title: |
p90 Ribosomal S6 kinase 2, a novel GPCR kinase, is required for growth factor-mediated attenuation of GPCR signaling. |
Volume: |
49 |
Issue: |
12 |
Pages: |
2657-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang MS |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells. |
Volume: |
404 |
Issue: |
1 |
Pages: |
133-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Law AJ |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. |
Volume: |
109 |
Issue: |
30 |
Pages: |
12165-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cahill ME |
Year: |
2013 |
Journal: |
J Neurochem |
Title: |
Neuregulin1 signaling promotes dendritic spine growth through kalirin. |
Volume: |
126 |
Issue: |
5 |
Pages: |
625-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wehr MC |
Year: |
2017 |
Journal: |
EMBO Mol Med |
Title: |
Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1448-1462 |
|
•
•
•
•
•
|
Publication |
First Author: |
Namba H |
Year: |
2017 |
Journal: |
J Neurochem |
Title: |
Epidermal growth factor signals attenuate phenotypic and functional development of neocortical GABA neurons. |
Volume: |
142 |
Issue: |
6 |
Pages: |
886-900 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen P |
Year: |
2021 |
Journal: |
Cell Death Dis |
Title: |
Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation. |
Volume: |
12 |
Issue: |
4 |
Pages: |
403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ng CF |
Year: |
2014 |
Journal: |
J Cell Biochem |
Title: |
Identification of FHL2-regulated genes in liver by microarray and bioinformatics analysis. |
Volume: |
115 |
Issue: |
4 |
Pages: |
744-53 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
76
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
700
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
300
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
695
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
285
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
483
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
483
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
724
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1319
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1068
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Morris JK |
Year: |
2006 |
Journal: |
Brain Res |
Title: |
A disorganized innervation of the inner ear persists in the absence of ErbB2. |
Volume: |
1091 |
Issue: |
1 |
Pages: |
186-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ricobaraza A |
Year: |
2023 |
Journal: |
J Mol Med (Berl) |
Title: |
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome. |
Volume: |
101 |
Issue: |
12 |
Pages: |
1587-1601 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gawande DY |
Year: |
2023 |
Journal: |
Biol Psychiatry |
Title: |
GluN2D Subunit in Parvalbumin Interneurons Regulates Prefrontal Cortex Feedforward Inhibitory Circuit and Molecular Networks Relevant to Schizophrenia. |
Volume: |
94 |
Issue: |
4 |
Pages: |
297-309 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2022 |
Journal: |
Front Med (Lausanne) |
Title: |
Podocyte-specific deletion of miR-146a increases podocyte injury and diabetic kidney disease. |
Volume: |
9 |
|
Pages: |
897188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mapes J |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy. |
Volume: |
13 |
Issue: |
3 |
Pages: |
e1006654 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krane IM |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice. |
Volume: |
12 |
Issue: |
8 |
Pages: |
1781-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
210
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Young CD |
Year: |
2008 |
Journal: |
Breast Cancer Res |
Title: |
Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. |
Volume: |
10 |
Issue: |
4 |
Pages: |
R70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Papaleo F |
Year: |
2016 |
Journal: |
J Neurosci |
Title: |
Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model. |
Volume: |
36 |
Issue: |
17 |
Pages: |
4859-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vullhorst D |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
Structural Similarities between Neuregulin 1-3 Isoforms Determine Their Subcellular Distribution and Signaling Mode in Central Neurons. |
Volume: |
37 |
Issue: |
21 |
Pages: |
5232-5249 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
El Hokayem J |
Year: |
2018 |
Journal: |
Mol Neurobiol |
Title: |
Loss of Angelman Syndrome Protein E6AP Disrupts a Novel Antagonistic Estrogen-Retinoic Acid Transcriptional Crosstalk in Neurons. |
Volume: |
55 |
Issue: |
9 |
Pages: |
7187-7200 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
604
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
433
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
663
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
640
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
637
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
485
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
603
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
459
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
423
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
462
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
645
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
734
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
156
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
305
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
857
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
643
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
206
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
241
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
247
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|