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Search results 1001 to 1100 out of 3232 for Erg

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Type Details Score
Publication
First Author: Reymond A
Year: 2002
Journal: Nature
Title: Human chromosome 21 gene expression atlas in the mouse.
Volume: 420
Issue: 6915
Pages: 582-6
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication    
First Author: Qu X
Year: 2019
Journal: JCI Insight
Title: Tie2 regulates endocardial sprouting and myocardial trabeculation.
Volume: 5
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
Publication
First Author: Gitton Y
Year: 2002
Journal: Nature
Title: A gene expression map of human chromosome 21 orthologues in the mouse.
Volume: 420
Issue: 6915
Pages: 586-90
Allele  
Name: glutamate receptor, metabotropic 6; no b wave 4
Allele Type: Chemically induced (ENU)
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Allele  
Name: small ERG 1; wild type
Allele Type: Not Specified
Allele  
Name: small ERG 2; wild type
Allele Type: Not Specified
Allele  
Name: small ERG 3; wild type
Allele Type: Not Specified
Allele  
Name: small ERG 4; wild type
Allele Type: Not Specified
Genotype
Symbol: serg1/serg1
Background: C57BL/6J-serg1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: serg2/serg2
Background: C57BL/6J-serg2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: serg3/serg3
Background: C57BL/6J-serg3
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: serg4/serg4
Background: C57BL/6J-serg4
Zygosity: hm
Has Mutant Allele: true
Publication      
First Author: Center for Functional Genomics (CFG) at Northwestern University
Year: 2005
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from Neurogenomics Project at Northwestern University
Protein
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 387  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 455  
Fragment?: false
Publication
First Author: Trudeau MC
Year: 1995
Journal: Science
Title: HERG, a human inward rectifier in the voltage-gated potassium channel family.
Volume: 269
Issue: 5220
Pages: 92-5
Publication
First Author: Chen J
Year: 1999
Journal: J Biol Chem
Title: Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.
Volume: 274
Issue: 15
Pages: 10113-8
Protein Domain
Type: Family
Description: Potassium channels are the most diverse group of the ion channel family [, ]. They are important in shaping the action potential, and in neuronal excitability and plasticity []. The potassium channel family is composed of several functionally distinct isoforms, which can be broadly separated into 2 groups []: the practically non-inactivating 'delayed' group and therapidly inactivating 'transient' group.These are all highly similar proteins, with only small amino acid changes causing the diversity of the voltage-dependent gating mechanism, channel conductance and toxin binding properties. Each type of K+channel is activated by different signals and conditions depending on their type of regulation: some open in response to depolarisation of the plasma membrane; others in response to hyperpolarisation or an increase in intracellular calcium concentration; some can be regulated by binding of a transmitter, together with intracellular kinases; while others are regulated by GTP-binding proteins or other second messengers []. In eukaryotic cells, K+channels are involved in neural signalling and generation of the cardiac rhythm, act as effectors in signal transduction pathways involving G protein-coupled receptors (GPCRs) and may have a role in target cell lysis by cytotoxic T-lymphocytes []. In prokaryotic cells, they play a role in the maintenance of ionic homeostasis [].All K+channels discovered so far possess a core of alpha subunits, each comprising either one or two copies of a highly conserved pore loop domain (P-domain). The P-domain contains the sequence (T/SxxTxGxG), which has been termed the K+selectivity sequence. In families that contain one P-domain, four subunits assemble to form a selective pathway for K+across the membrane. However, it remains unclear how the 2 P-domain subunits assemble to form a selective pore. The functional diversity of these families can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. K+channel subunits containing one pore domain can be assigned into one of two superfamilies: those that possess six transmembrane (TM) domains and those that possess only two TM domains. The six TM domain superfamily can be further subdivided into conserved gene families: the voltage-gated (Kv) channels; the KCNQ channels (originally known as KvLQT channels); the EAG-like K+channels; and three types of calcium (Ca)-activated K+channels (BK, IK and SK) []. The 2TM domain family comprises inward-rectifying K+channels. In addition, there are K+channel alpha-subunits that possess two P-domains. These are usually highly regulated K+selective leak channels.The first EAG K+ channel was identified in Drosophila melanogaster (Fruit fly), following a screen for mutations giving rise to behavioural abnormalities. Disruption of the Eag gene caused an ether-induced, leg-shaking behaviour. Subsequent studies have revealed a conserved multi-gene family of EAG-like K+ channels, which are present in human and many other species. Based on the varying functional properties of the channels, the family has been divided into 3 subfamilies: EAG, ELK and ERG. Interestingly, Caenorhabditis elegans appears to lack the ELK type [].The human ether-a-go-go-related gene (HERG), cloned from hippocampus, shares 49% amino acid identity with EAG. It is also found in the heart, where it helps to control K+ efflux []. Mutations in HERG result in the disruption of the repolarising current and the disease LQT2 syndrome, an inheriteddisorder of cardiac repolarisation that predisposes affected individuals tolife-threatening arrhythmias [].
Publication
First Author: Cai C
Year: 2013
Journal: J Clin Invest
Title: ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.
Volume: 123
Issue: 3
Pages: 1109-22
Publication  
First Author: Charette JR
Year: 2016
Journal: Adv Exp Med Biol
Title: A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.
Volume: 854
Pages: 177-83
Publication
First Author: Shirato S
Year: 2008
Journal: Exp Eye Res
Title: Postreceptoral contributions to the light-adapted ERG of mice lacking b-waves.
Volume: 86
Issue: 6
Pages: 914-28
Publication
First Author: Ding D
Year: 2023
Journal: Nat Commun
Title: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.
Volume: 14
Issue: 1
Pages: 4671
Publication
First Author: Klezovitch O
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A causal role for ERG in neoplastic transformation of prostate epithelium.
Volume: 105
Issue: 6
Pages: 2105-10
Publication
First Author: Linn DE
Year: 2016
Journal: Cancer Res
Title: Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression.
Volume: 76
Issue: 7
Pages: 1869-81
Publication
First Author: Stankiewicz MJ
Year: 2013
Journal: Leukemia
Title: AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL.
Volume: 27
Issue: 6
Pages: 1339-47
Publication  
First Author: D'Amico G
Year: 2022
Journal: Development
Title: ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.
Volume: 149
Issue: 13
Publication
First Author: Tang M
Year: 1997
Journal: Exp Eye Res
Title: ERG abnormalities in relation to histopathologic findings in vitiligo mutant mice.
Volume: 65
Issue: 2
Pages: 215-22
Publication
First Author: Carver BS
Year: 2009
Journal: Nat Genet
Title: Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Volume: 41
Issue: 5
Pages: 619-24
Publication    
First Author: Mounir Z
Year: 2016
Journal: Elife
Title: ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor.
Volume: 5
GXD Expression
Probe: MGI:3798170
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-06-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7647200
Age: embryonic day 8.5
Image: 1K
Note: Co-expression with Erg in endothelial cells.
Specimen Label: 1K
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3798170
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-06-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7647200
Age: embryonic day 8.5
Image: 1L
Note: Co-expression with Erg in endothelial cells.
Specimen Label: 1L
Detected: true
Specimen Num: 2
Publication
First Author: Yang L
Year: 2003
Journal: Biochem J
Title: An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B.
Volume: 369
Issue: Pt 3
Pages: 651-7
Publication
First Author: Bush RA
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Cone ERG Changes During Light Adaptation in Two All-Cone Mutant Mice: Implications for Rod-Cone Pathway Interactions.
Volume: 60
Issue: 10
Pages: 3680-3688
Publication
First Author: Antes R
Year: 2013
Journal: PLoS One
Title: ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice.
Volume: 8
Issue: 5
Pages: e64949
Publication
First Author: Rohrer B
Year: 2003
Journal: Invest Ophthalmol Vis Sci
Title: Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging.
Volume: 44
Issue: 1
Pages: 310-5
Publication
First Author: Gargini C
Year: 2007
Journal: J Comp Neurol
Title: Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study.
Volume: 500
Issue: 2
Pages: 222-38
Publication  
First Author: Li Y
Year: 2020
Journal: Front Cell Neurosci
Title: Rod and Cone Coupling Modulates Photopic ERG Responses in the Mouse Retina.
Volume: 14
Pages: 566712
Publication
First Author: Fairless R
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE.
Volume: 61
Issue: 5
Pages: 37
Publication
First Author: Cibis GW
Year: 1993
Journal: Invest Ophthalmol Vis Sci
Title: The effects of dystrophin gene mutations on the ERG in mice and humans.
Volume: 34
Issue: 13
Pages: 3646-52
Publication
First Author: Ohya S
Year: 2002
Journal: Am J Physiol Cell Physiol
Title: Functional and molecular identification of ERG channels in murine portal vein myocytes.
Volume: 283
Issue: 3
Pages: C866-77
Publication
First Author: Furlan F
Year: 2005
Journal: Neuroscience
Title: Interneurons transiently express the ERG K+ channels during development of mouse spinal networks in vitro.
Volume: 135
Issue: 4
Pages: 1179-92
Publication
First Author: Hardy AB
Year: 2009
Journal: J Biol Chem
Title: Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets.
Volume: 284
Issue: 44
Pages: 30441-52
Publication
First Author: Lees-Miller JP
Year: 1997
Journal: Circ Res
Title: Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts.
Volume: 81
Issue: 5
Pages: 719-26
Publication
First Author: Casey OM
Year: 2012
Journal: PLoS One
Title: TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation.
Volume: 7
Issue: 7
Pages: e41668
Publication
First Author: Kim HJ
Year: 2023
Journal: Sci Rep
Title: ERG K(+) channels mediate a major component of action potential repolarization in lymphatic muscle.
Volume: 13
Issue: 1
Pages: 14890
Publication
First Author: Bayer AU
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Retinal morphology and ERG response in the DBA/2NNia mouse model of angle-closure glaucoma.
Volume: 42
Issue: 6
Pages: 1258-65
Publication  
First Author: Marcus DM
Year: 2000
Journal: Mol Vis
Title: Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption.
Volume: 6
Pages: 169-77
Publication  
First Author: Dhingra A
Year: 2014
Journal: Front Mol Neurosci
Title: PDE9A is expressed in the inner retina and contributes to the normal shape of the photopic ERG waveform.
Volume: 7
Pages: 60
Publication
First Author: Pond AL
Year: 2000
Journal: J Biol Chem
Title: Expression of distinct ERG proteins in rat, mouse, and human heart. Relation to functional I(Kr) channels.
Volume: 275
Issue: 8
Pages: 5997-6006
Publication
First Author: Royer A
Year: 2005
Journal: Cardiovasc Res
Title: Expression of human ERG K+ channels in the mouse heart exerts anti-arrhythmic activity.
Volume: 65
Issue: 1
Pages: 128-37
Protein
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
Interaction Experiment
Description: Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.
Transgene
Type: transgene
Organism: mouse, laboratory
Publication
First Author: Kameya S
Year: 1997
Journal: Hum Mol Genet
Title: Dp260 disrupted mice revealed prolonged implicit time of the b-wave in ERG and loss of accumulation of beta-dystroglycan in the outer plexiform layer of the retina.
Volume: 6
Issue: 13
Pages: 2195-203
Publication
First Author: Zeng Y
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis.
Volume: 45
Issue: 9
Pages: 3279-85
Publication
First Author: Corona M
Year: 2002
Journal: FEBS Lett
Title: A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.
Volume: 532
Issue: 1-2
Pages: 121-6
GXD Expression  
Probe: MGI:7311817
Assay Type: Immunohistochemistry
Annotation Date: 2025-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7861845
Age: embryonic day 17.5
Note: Authors report a decrease in pulmonary endothelial cells co-expressing Sparcl1 and Erg from E17.5 to postnatal day 7.
Specimen Label: 7D E17.5 SPARCL1
Detected: true
Specimen Num: 1