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Search results 1001 to 1038 out of 1038 for Foxc1

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Type Details Score
Allele
Bmp4<tm1Blh> | MGI:1857137
Name: bone morphogenetic protein 4; targeted mutation 1, Brigid L Hogan
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Bmp4/Bmp4<+>
Background: B6.129S2-Bmp4
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110122 | Axenfeld-Rieger syndrome type 3
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DO Term
DOID:0080608 | anterior segment dysgenesis 3
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Publication
15684392 | -
First Author: Berry FB
Year: 2005
Journal: Mol Cell Biol
Title: FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner.
Volume: 25
Issue: 4
Pages: 1415-24
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GXD Expression
GXD Expression
Probe: MGI:6324499
Assay Type: RNA in situ
Annotation Date: 2019-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6324509
Age: embryonic day 15.5
Image: 1N
Note: Authors report lower levels of expression in osteoblast of mandible and perichondrium of Meckel's cartilage in both wild type and -/- embryos compared with Foxc1 expression.
Specimen Label: 1N
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6324499
Assay Type: RNA in situ
Annotation Date: 2019-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6324509
Age: embryonic day 15.5
Image: 1O
Note: Authors report lower levels of expression in osteoblast of mandible and perichondrium of Meckel's cartilage in both wild type and -/- embryos compared with Foxc1 expression.
Specimen Label: 1O
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6324499
Assay Type: RNA in situ
Annotation Date: 2019-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6324509
Age: embryonic day 15.5
Image: 1N
Note: Authors report lower levels of expression in osteoblast of mandible and perichondrium of Meckel's cartilage in both wild type and -/- embryos compared with Foxc1 expression.
Specimen Label: 1N
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6324499
Assay Type: RNA in situ
Annotation Date: 2019-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6324509
Age: embryonic day 15.5
Image: 1O
Note: Authors report lower levels of expression in osteoblast of mandible and perichondrium of Meckel's cartilage in both wild type and -/- embryos compared with Foxc1 expression.
Specimen Label: 1O
Detected: true
Specimen Num: 8
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Publication
16449236 | -
First Author: Berry FB
Year: 2006
Journal: Hum Mol Genet
Title: Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis.
Volume: 15
Issue: 6
Pages: 905-19
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Publication
22493429 | -
First Author: Danciu TE
Year: 2012
Journal: J Biol Chem
Title: Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2.
Volume: 287
Issue: 22
Pages: 18318-29
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Allele
Pax6<7Neu> | MGI:2156738
 
Name: paired box 6; 7, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Pax6<4Neu> | MGI:2156741
 
Name: paired box 6; 4, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Pax6<3Neu> | MGI:2156742
 
Name: paired box 6; 3, Neuherberg
Allele Type: Chemically induced (ENU)
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Allele
Pax6<1Jrt> | MGI:2680557
 
Name: paired box 6; 1, Janet Rossant
Allele Type: Chemically induced (ENU)
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Allele
Pax6<tm2Pgr> | MGI:1934348
Name: paired box 6; targeted mutation 2, Peter Gruss
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Pax6<1Jrt>/Pax6<+>
Background: C3.B6-Pax6<1Jrt>
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<3Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<4Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6<7Neu>/Pax6<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0060673 | Peters anomaly
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HT Experiment
GSE249782 | Characterization of age-associated gene expression changes in mouse sweat glands [FP_WT_TA]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE249783 | Characterization of age-associated gene expression changes in mouse sweat glands [FP_YO]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Genotype
Genotype
Symbol: Pax6/Pax6<+> Tg(Pax6-cre,GFP)1Pgr/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
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Gene
1545 | CYP1B1
Type: gene
Organism: human
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HT Experiment
GSE269283 | Meningeal-derived retinoic acid regulates neurogenesis via suppression of Notch and Sox2 [Spatial Transcriptomics]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Coding Gene
MGI:88180 | Bmp4
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE244964 | Gene Expression profile at the single cell level of quiescent and activated muscle stem cells (MuSC) from Extraocular muscle (EOM) and Tibialis Anterior (TA) muscle
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
27771509 | J:256746
First Author: Wang X
Year: 2017
Journal: Biochim Biophys Acta
Title: A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye.
Volume: 1863
Issue: 1
Pages: 60-67
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Publication
35876806 | J:327413
 
First Author: Gillnäs S
Year: 2022
Journal: Biol Open
Title: Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development.
Volume: 11
Issue: 8
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Publication
35551452 | J:324888
First Author: Omatsu Y
Year: 2022
Journal: Nat Commun
Title: Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.
Volume: 13
Issue: 1
Pages: 2654
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Protein Coding Gene
MGI:97490 | Pax6
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
38637019 | J:357378
First Author: Zonnefeld AG
Year: 2024
Journal: Aging (Albany NY)
Title: Characterization of age-associated gene expression changes in mouse sweat glands.
Volume: 16
Issue: 8
Pages: 6717-6730
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Publication
25202984 | J:217296
First Author: Thomson BR
Year: 2014
Journal: J Clin Invest
Title: A lymphatic defect causes ocular hypertension and glaucoma in mice.
Volume: 124
Issue: 10
Pages: 4320-4
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Publication
15509533 | J:93634
First Author: Holmberg J
Year: 2004
Journal: Am J Pathol
Title: PITX2 gain-of-function in Rieger syndrome eye model.
Volume: 165
Issue: 5
Pages: 1633-41
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Publication
30055071 | J:266674
First Author: Flach H
Year: 2018
Journal: Dev Dyn
Title: Nosip functions during vertebrate eye and cranial cartilage development.
Volume: 247
Issue: 9
Pages: 1070-1082
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Publication
38240380 | J:345834
 
First Author: Girolamo DD
Year: 2024
Journal: Development
Title: Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures.
Volume: 151
Issue: 4
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Publication
17065505 | J:123091
First Author: Asai-Coakwell M
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Reduced human and murine corneal thickness in an Axenfeld-Rieger syndrome subtype.
Volume: 47
Issue: 11
Pages: 4905-9
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