| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
483
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1098
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, transgenic, congenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maines MD |
| Year: |
1998 |
| Journal: |
J Neurochem |
| Title: |
Neuronal overexpression of heme oxygenase-1 correlates with an attenuated exploratory behavior and causes an increase in neuronal NADPH diaphorase staining. |
| Volume: |
70 |
| Issue: |
5 |
| Pages: |
2057-69 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Eno2-Hmox1)2Main/Tg(Eno2-Hmox1)2Main |
| Background: |
involves: C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1528
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
105
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1274
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kropp J |
| Year: |
2015 |
| Journal: |
Biochem J |
| Title: |
miR-98 delays skeletal muscle differentiation by down-regulating E2F5. |
| Volume: |
466 |
| Issue: |
1 |
| Pages: |
85-93 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2453
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
428
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1462
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1447
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
608
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2472
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
527
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
514
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Forootan SS |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
16084 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng Z |
| Year: |
2009 |
| Journal: |
Nat Med |
| Title: |
Foxo1 integrates insulin signaling with mitochondrial function in the liver. |
| Volume: |
15 |
| Issue: |
11 |
| Pages: |
1307-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawahara G |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. |
| Volume: |
23 |
| Issue: |
7 |
| Pages: |
1869-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davies R |
| Year: |
2005 |
| Journal: |
Am J Pathol |
| Title: |
Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool. |
| Volume: |
166 |
| Issue: |
4 |
| Pages: |
1041-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang X |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Ferroptosis as a target for protection against cardiomyopathy. |
| Volume: |
116 |
| Issue: |
7 |
| Pages: |
2672-2680 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lämsä V |
| Year: |
2012 |
| Journal: |
Toxicol Sci |
| Title: |
Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2. |
| Volume: |
130 |
| Issue: |
1 |
| Pages: |
132-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marques L |
| Year: |
2016 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Iron gene expression profile in atherogenic Mox macrophages. |
| Volume: |
1862 |
| Issue: |
6 |
| Pages: |
1137-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reddy NM |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0129676 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jez M |
| Year: |
2017 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Valproic acid downregulates heme oxygenase-1 independently of Nrf2 by increasing ubiquitination and proteasomal degradation. |
| Volume: |
485 |
| Issue: |
1 |
| Pages: |
160-166 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McNeilly AD |
| Year: |
2016 |
| Journal: |
Diabetes |
| Title: |
Nrf2-Mediated Neuroprotection Against Recurrent Hypoglycemia Is Insufficient to Prevent Cognitive Impairment in a Rodent Model of Type 1 Diabetes. |
| Volume: |
65 |
| Issue: |
10 |
| Pages: |
3151-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim C |
| Year: |
2017 |
| Journal: |
Neurochem Int |
| Title: |
An X-chromosome linked mouse model (Ndufa1S55A) for systemic partial Complex I deficiency for studying predisposition to neurodegeneration and other diseases. |
| Volume: |
109 |
|
| Pages: |
78-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li J |
| Year: |
2023 |
| Journal: |
Front Immunol |
| Title: |
TLR7 modulates extramedullary splenic erythropoiesis in P. yoelii NSM-infected mice through the regulation of iron metabolism of macrophages with IFN-γ. |
| Volume: |
14 |
|
| Pages: |
1123074 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo X |
| Year: |
2014 |
| Journal: |
Am J Pathol |
| Title: |
PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina. |
| Volume: |
184 |
| Issue: |
4 |
| Pages: |
1017-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Griñán-Ferré C |
| Year: |
2018 |
| Journal: |
Front Cell Neurosci |
| Title: |
Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model. |
| Volume: |
12 |
|
| Pages: |
224 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu L |
| Year: |
2023 |
| Journal: |
Redox Biol |
| Title: |
Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages. |
| Volume: |
61 |
|
| Pages: |
102638 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiang J |
| Year: |
2018 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Lens Epithelial Cells Initiate an Inflammatory Response Following Cataract Surgery. |
| Volume: |
59 |
| Issue: |
12 |
| Pages: |
4986-4997 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dunigan K |
| Year: |
2018 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanisms. |
| Volume: |
315 |
| Issue: |
4 |
| Pages: |
L545-L552 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2441
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
467
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Andrew AK |
| Year: |
2022 |
| Journal: |
PLoS One |
| Title: |
A novel murine model of post-implantation malaria-induced preterm birth. |
| Volume: |
17 |
| Issue: |
3 |
| Pages: |
e0256060 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kobayashi K |
| Year: |
2019 |
| Journal: |
BMC Genomics |
| Title: |
Transcriptome analysis of the effect of C-C chemokine receptor 5 deficiency on cell response to Toxoplasma gondii in brain cells. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ungvari Z |
| Year: |
2011 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. |
| Volume: |
300 |
| Issue: |
4 |
| Pages: |
H1133-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiao H |
| Year: |
2020 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Comparison of Neuroprotective Effects of Monomethylfumarate to the Sigma 1 Receptor Ligand (+)-Pentazocine in a Murine Model of Retinitis Pigmentosa. |
| Volume: |
61 |
| Issue: |
3 |
| Pages: |
5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sung HY |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer's Disease. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
e0153156 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li H |
| Year: |
2021 |
| Journal: |
Mol Neurodegener |
| Title: |
High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li M |
| Year: |
2016 |
| Journal: |
Circulation |
| Title: |
Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1. |
| Volume: |
134 |
| Issue: |
15 |
| Pages: |
1105-1121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Obata A |
| Year: |
2019 |
| Journal: |
Diabetologia |
| Title: |
Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice. |
| Volume: |
62 |
| Issue: |
7 |
| Pages: |
1225-1236 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
European Mouse Mutant Archive |
| Year: |
2003 |
| Journal: |
Unpublished |
| Title: |
Information obtained from the European Mouse Mutant Archive (EMMA) |
|
|
|
|
•
•
•
•
•
|