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Search results 1001 to 1100 out of 2139 for Lck

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Type Details Score
Publication
First Author: Zhang B
Year: 2018
Journal: J Immunol
Title: Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity.
Volume: 201
Issue: 5
Pages: 1452-1459
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Baljit Khakh
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
Genotype
Symbol: Socs1/Socs1 Tg(Lck-cre)I57Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Casp8/Casp8 Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Arnt/Arnt Tg(Lck-cre)I57Jxm/?
Background: involves: 129X1/SvJ * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Stam/Stam Stam2/Stam2 Tg(Lck-cre)I57Jxm/?
Background: involves: 129S4/SvJae * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ikbkb/Ikbkb Tg(Lck-cre)I57Jxm/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd4/Cd4 Tg(Lck-cre)3785Nik/?
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lmo2/Lmo2 Tg(Lck-cre)1Thr/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cflar/Cflar Tg(Lck-cre)548Jxm/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc Tg(Lck-cre)1Cwi/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ep300/Ep300 Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Crebbp/Crebbp Tg(Lck-cre)548Jxm/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Lck-cre)548Jxm/?
Background: involves: 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Zap70/Zap70 Tg(Lck-ZAP70)824Saka/?
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ikzf1/Ikzf1<+> Tg(Lck-cre)1Cwi/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Map3k7/Map3k7 Tg(Lck-cre)548Jxm/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dntt/Dntt
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kmt2a/Kmt2a<+> Mllt3/Mllt3<+> Tg(Lck-cre)1Thr/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kmt2a/Kmt2a<+> Mllt1/Mllt1<+> Tg(Lck-cre)1Thr/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fbxw7/Fbxw7 Trp53/Trp53 Tg(Lck-cre)1Cwi/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd19/Cd19<+> Ltb/Ltb Tg(Lck-cre)1Jtak/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Jak3/Jak3 Tg(Lck-Jak3)2Ljb/?
Background: involves: 129S4/SvJae * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Jak3/Jak3 Tg(Lck-Jak3)1Ljb/?
Background: involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/10
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Jak3/Jak3 Tg(Lck-Jak3)2Ljb/?
Background: involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/10
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Lck-cre)I57Jxm/? Traf2/Traf2
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cops5/Cops5 Tg(Lck-cre)548Jxm/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Lck-cre)548Jxm/? Upf2/Upf2
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(LCKprBCL2)36Sjk/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Mcl1/Mcl1 Tg(Lck-cre)548Jxm/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Lck-Akt1*)M-1Pnt/?
Background: involves: C3H/He * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Akt1/Akt1 Akt3/Akt3 Tg(Lck-cre)1Cwi/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tcra/Tcra Tg(Lck-Akt1*E40K)E-3Pnt/?
Background: involves: 129S2/SvPas * C3H/He * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Tox)1Kay/? Tox/Tox
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ctcf/Ctcf Rag2/Rag2 Tg(Lck-cre)1Cwi/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Smarca4/Smarca4 Tg(Lck-cre)1Cwi/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdk6/Cdk6 Tg(Lck-Akt1*E40K)E-3Pnt/?
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cdk6/Cdk6<+> Tg(Lck-Akt1*E40K)E-3Pnt/?
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Brca1/Brca1 Tg(BCL2)36Wehi/? Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(LCK-NFKBIA)5Dwb/? Tg(Tcra,Tcrb)1Mcd/?
Background: involves: BALB/c * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cr1l/Cr1l Tg(Lck-cre)548Jxm/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Map3k3/Map3k3 Tg(Lck-cre)1Jtak/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Lck-Tal1)4709Led/?
Background: FVB/N-Tg(Lck-Tal1)4709Led
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Lck-cre)548Jxm/? Tgfb1/Tgfb1
Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Shc1/Shc1 Tg(Lck-cre)1Cwi/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gata3/Gata3 Tg(Lck-cre)1Cwi/?
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myh9/Myh9 Tg(Lck-cre)#Nik/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hes1/Hes1 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atg3/Atg3 Tg(Lck-cre)548Jxm/?
Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rag2/Rag2 Sos1/Sos1 Tg(Lck-cre)1Cwi/?
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ptpn11/Ptpn11<+> Tg(Lck-cre)1Cwi/?
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Taf7/Taf7 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hnrnpl/Hnrnpl Tg(Lck-cre)548Jxm/?
Background: B6.Cg-Hnrnpl Tg(Lck-cre)548Jxm
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nr3c1/Nr3c1<+> Tg(Lck-cre)548Jxm/?
Background: B6.Cg-Nr3c1 Tg(Lck-cre)548Jxm
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nr3c1/Nr3c1 Tg(Lck-cre)548Jxm/?
Background: B6.Cg-Nr3c1 Tg(Lck-cre)548Jxm
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hdac1/Hdac1 Hdac2/Hdac2<+> Tg(Lck-cre)1Cwi/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hdac1/Hdac1<+> Hdac2/Hdac2 Tg(Lck-cre)1Cwi/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hdac1/Hdac1 Hdac2/Hdac2 Tg(Lck-cre)1Cwi/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Septin9/Septin9 Tg(Lck-cre)548Jxm/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lck-cre)I57Jxm/?
Background: involves: 129S6/SvEvTac * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Snai3/Snai3 Tg(Lck-cre)548Jxm/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(LCKprBCL2)36Sjk/?
Background: B6.Cg-Tg(LCKprBCL2)36Sjk
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(LCKprBCL2)36Sjk/?
Background: involves: C57BL/6 * CBA/J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Vdac2/Vdac2 Bak1/Bak1 Tg(Lck-cre)1Cwi/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bak1/Bak1 Bax/Bax Tg(Lck-cre)1Cwi/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkd2/Prkd2 Prkd3/Prkd3 Tg(Lck-cre)1Jtak/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nop53/Nop53 Tg(Lck-cre)#Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Setd2/Setd2 Tg(Lck-cre)#Zhu/?
Background: involves: C57BL/6 * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prdm1/Prdm1 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcap31/Bcap31 Tg(Lck-cre)548Jxm/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Zfp131/Zfp131 Tg(Lck-cre)1Jtak/?
Background: involves: C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prdm1/Prdm1 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Tanaka Y
Year: 2003
Journal: Immunity
Title: SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells.
Volume: 18
Issue: 3
Pages: 403-14
Publication
First Author: Guo L
Year: 2010
Journal: Eur J Immunol
Title: Inhibition of clonal expansion by Foxp3 expression as a mechanism of controlled T-cell responses and autoimmune disease.
Volume: 40
Issue: 1
Pages: 71-80
Publication
First Author: Komal P
Year: 2014
Journal: J Neurosci
Title: T-cell receptor activation decreases excitability of cortical interneurons by inhibiting α7 nicotinic receptors.
Volume: 34
Issue: 1
Pages: 22-35
Publication
First Author: Holland SJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The T-cell receptor is not hardwired to engage MHC ligands.
Volume: 109
Issue: 45
Pages: E3111-8
Publication
First Author: Chodaczek G
Year: 2012
Journal: Nat Immunol
Title: Body-barrier surveillance by epidermal γδ TCRs.
Volume: 13
Issue: 3
Pages: 272-82
Publication
First Author: Fragoso RC
Year: 2006
Journal: J Immunol
Title: A CD8/Lck transgene is able to drive thymocyte differentiation.
Volume: 177
Issue: 9
Pages: 6007-17
Publication
First Author: Vang KB
Year: 2010
Journal: J Immunol
Title: Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development.
Volume: 184
Issue: 8
Pages: 4074-7
Publication
First Author: Zikherman J
Year: 2010
Journal: Immunity
Title: CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.
Volume: 32
Issue: 3
Pages: 342-54
Publication
First Author: Pingel S
Year: 1999
Journal: Eur J Immunol
Title: The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
Volume: 29
Issue: 8
Pages: 2376-84
Publication
First Author: Dighe AS
Year: 1995
Journal: Immunity
Title: Tissue-specific targeting of cytokine unresponsiveness in transgenic mice.
Volume: 3
Issue: 5
Pages: 657-66
Publication
First Author: Haks MC
Year: 2005
Journal: Immunity
Title: Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.
Volume: 22
Issue: 5
Pages: 595-606
Publication
First Author: Schmedt C
Year: 1998
Journal: Nature
Title: Csk controls antigen receptor-mediated development and selection of T-lineage cells.
Volume: 394
Issue: 6696
Pages: 901-4
Publication
First Author: Jiao A
Year: 2022
Journal: Sci Adv
Title: DExD/H-box helicase 9 intrinsically controls CD8+ T cell-mediated antiviral response through noncanonical mechanisms.
Volume: 8
Issue: 6
Pages: eabk2691
Publication
First Author: Gorman JA
Year: 2012
Journal: J Immunol
Title: The cytoskeletal adaptor protein IQGAP1 regulates TCR-mediated signaling and filamentous actin dynamics.
Volume: 188
Issue: 12
Pages: 6135-44
Publication
First Author: Matsuda A
Year: 1998
Journal: J Exp Med
Title: Disruption of lymphocyte function and signaling in CD45-associated protein-null mice.
Volume: 187
Issue: 11
Pages: 1863-70
Publication
First Author: Ashe JM
Year: 1999
Journal: J Exp Med
Title: ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
Volume: 189
Issue: 7
Pages: 1163-8
Publication
First Author: Rudolph B
Year: 2001
Journal: Oncogene
Title: Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation.
Volume: 20
Issue: 10
Pages: 1164-75
Publication
First Author: Dunlock VE
Year: 2022
Journal: Cell Rep
Title: Tetraspanin CD53 controls T cell immunity through regulation of CD45RO stability, mobility, and function.
Volume: 39
Issue: 13
Pages: 111006
Publication
First Author: Bosselut R
Year: 2000
Journal: Immunity
Title: Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus.
Volume: 12
Issue: 4
Pages: 409-18
Publication
First Author: Glassman CR
Year: 2018
Journal: Cell Rep
Title: Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex.
Volume: 22
Issue: 5
Pages: 1263-1275
Publication
First Author: Klammt C
Year: 2015
Journal: Nat Immunol
Title: T cell receptor dwell times control the kinase activity of Zap70.
Volume: 16
Issue: 9
Pages: 961-9
Publication
First Author: Jin Q
Year: 2022
Journal: Sci Adv
Title: Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Volume: 8
Issue: 49
Pages: eabq8437
Publication
First Author: McGuire EA
Year: 1992
Journal: Mol Cell Biol
Title: Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma.
Volume: 12
Issue: 9
Pages: 4186-96
Publication
First Author: Round JL
Year: 2007
Journal: Nat Immunol
Title: Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors.
Volume: 8
Issue: 2
Pages: 154-61
Publication
First Author: Kikuchi K
Year: 2001
Journal: Int Immunol
Title: Suppression of thymic development by the dominant-negative form of Gads.
Volume: 13
Issue: 6
Pages: 777-83
Publication
First Author: Fukuyama H
Year: 2002
Journal: Eur J Immunol
Title: Requirement of Fas expression in B cells for tolerance induction.
Volume: 32
Issue: 1
Pages: 223-30
Publication
First Author: Wayne J
Year: 1994
Journal: J Immunol
Title: TCR selection and allelic exclusion in RAG transgenic mice that exhibit abnormal T cell localization in lymph nodes and lymphatics.
Volume: 153
Issue: 12
Pages: 5491-502
Publication
First Author: Suzuki R
Year: 2002
Journal: Int Immunol
Title: Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta.
Volume: 14
Issue: 4
Pages: 339-45