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Search results 1001 to 1100 out of 1184 for Lpl

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Type Details Score
Publication
First Author: Memetimin H
Year: 2022
Journal: Sci Rep
Title: Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes.
Volume: 12
Issue: 1
Pages: 22291
Publication
First Author: Wu Z
Year: 2020
Journal: Cell Death Differ
Title: Tumor suppressor ZHX2 inhibits NAFLD-HCC progression via blocking LPL-mediated lipid uptake.
Volume: 27
Issue: 5
Pages: 1693-1708
Publication
First Author: Lin X
Year: 2023
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Aerobic exercise-induced decrease of chemerin improved glucose and lipid metabolism and fatty liver of diabetes mice through key metabolism enzymes and proteins.
Volume: 1868
Issue: 12
Pages: 159409
Publication
First Author: Boren J
Year: 2001
Journal: J Biol Chem
Title: Binding of low density lipoproteins to lipoprotein lipase is dependent on lipids but not on apolipoprotein B.
Volume: 276
Issue: 29
Pages: 26916-22
Publication
First Author: Kwon JY
Year: 2001
Journal: Biol Reprod
Title: Molecular characterization of putative yolk processing enzymes and their expression during oogenesis and embryogenesis in rainbow trout (Oncorhynchus mykiss).
Volume: 65
Issue: 6
Pages: 1701-9
Publication
First Author: Renier G
Year: 1993
Journal: Arterioscler Thromb
Title: High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis.
Volume: 13
Issue: 2
Pages: 190-6
Publication
First Author: Hill MR
Year: 1997
Journal: Endocrinology
Title: Decreased expression of murine PPARgamma in adipose tissue during endotoxemia.
Volume: 138
Issue: 7
Pages: 3073-6
Publication
First Author: Yang WS
Year: 1998
Journal: J Lipid Res
Title: Sp1 and Sp3 transactivate the human lipoprotein lipase gene promoter through binding to a CT element: synergy with the sterol regulatory element binding protein and reduced transactivation of a naturally occurring promoter variant.
Volume: 39
Issue: 10
Pages: 2054-64
Publication
First Author: Kawamura I
Year: 1999
Journal: Anticancer Res
Title: Activation of lipoprotein lipase and inhibition of B16 melanoma-induced cachexia in mice by ponalrestat, an aldose reductase inhibitor.
Volume: 19
Issue: 1A
Pages: 341-8
Publication
First Author: Takahashi N
Year: 2002
Journal: J Biol Chem
Title: Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma.
Volume: 277
Issue: 19
Pages: 16906-12
Publication
First Author: Manzano M
Year: 2002
Journal: J Nutr
Title: Absolute counts and distribution of lymphocyte subsets in small intestine of BALB/c mice change during weaning.
Volume: 132
Issue: 9
Pages: 2757-62
Publication
First Author: Yu X
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart.
Volume: 102
Issue: 5
Pages: 1767-72
Publication
First Author: Shimada M
Year: 1993
Journal: J Biol Chem
Title: Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia.
Volume: 268
Issue: 24
Pages: 17924-9
Publication
First Author: Bergman BC
Year: 2006
Journal: Metabolism
Title: Fasting decreases free fatty acid turnover in mice overexpressing skeletal muscle lipoprotein lipase.
Volume: 55
Issue: 11
Pages: 1481-7
Publication
First Author: Little MC
Year: 2005
Journal: J Immunol
Title: The characterization of intraepithelial lymphocytes, lamina propria leukocytes, and isolated lymphoid follicles in the large intestine of mice infected with the intestinal nematode parasite Trichuris muris.
Volume: 175
Issue: 10
Pages: 6713-22
Publication
First Author: Jensen DR
Year: 2008
Journal: J Lipid Res
Title: Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?
Volume: 49
Issue: 4
Pages: 870-9
Publication
First Author: Wilson K
Year: 2001
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice.
Volume: 21
Issue: 11
Pages: 1809-15
Publication
First Author: Lichtenstein L
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.
Volume: 27
Issue: 11
Pages: 2420-7
Publication
First Author: Gin P
Year: 2008
Journal: J Biol Chem
Title: The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.
Volume: 283
Issue: 43
Pages: 29554-62
Publication
First Author: Perdomo G
Year: 2010
Journal: J Lipid Res
Title: A role of apolipoprotein D in triglyceride metabolism.
Volume: 51
Issue: 6
Pages: 1298-311
Publication
First Author: Voss CV
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1.
Volume: 108
Issue: 19
Pages: 7980-4
Publication
First Author: Todd EM
Year: 2011
Journal: J Immunol
Title: The actin-bundling protein L-plastin is essential for marginal zone B cell development.
Volume: 187
Issue: 6
Pages: 3015-25
Publication
First Author: Yamazaki T
Year: 2012
Journal: J Lipid Res
Title: The ddY mouse: a model of postprandial hypertriglyceridemia in response to dietary fat.
Volume: 53
Issue: 10
Pages: 2024-37
Publication
First Author: Lai PY
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Active form Notch4 promotes the proliferation and differentiation of 3T3-L1 preadipocytes.
Volume: 430
Issue: 3
Pages: 1132-9
Publication
First Author: Arany PR
Year: 2014
Journal: Sci Transl Med
Title: Photoactivation of endogenous latent transforming growth factor-β1 directs dental stem cell differentiation for regeneration.
Volume: 6
Issue: 238
Pages: 238ra69
Publication
First Author: McQueen AE
Year: 2017
Journal: J Biol Chem
Title: The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure.
Volume: 292
Issue: 39
Pages: 16122-16134
Publication
First Author: Frisdal E
Year: 2015
Journal: Diabetes
Title: Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity.
Volume: 64
Issue: 3
Pages: 840-55
Publication
First Author: Allan CM
Year: 2019
Journal: J Lipid Res
Title: An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner.
Volume: 60
Issue: 4
Pages: 869-879
Publication
First Author: Zhen Z
Year: 2019
Journal: Biochem Biophys Res Commun
Title: The lncRNA DAPK-IT1 regulates cholesterol metabolism and inflammatory response in macrophages and promotes atherogenesis.
Volume: 516
Issue: 4
Pages: 1234-1241
Publication
First Author: Basu D
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Mechanism of Increased LDL (Low-Density Lipoprotein) and Decreased Triglycerides With SGLT2 (Sodium-Glucose Cotransporter 2) Inhibition.
Volume: 38
Issue: 9
Pages: 2207-2216
Publication  
First Author: Oldoni F
Year: 2020
Journal: JCI Insight
Title: ANGPTL8 has both endocrine and autocrine effects on substrate utilization.
Volume: 5
Issue: 17
Publication
First Author: Hoekstra M
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Disruption of Phospholipid Transfer Protein-Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications.
Volume: 40
Issue: 3
Pages: 611-623
Publication  
First Author: Lu X
Year: 2020
Journal: Front Immunol
Title: Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis.
Volume: 11
Pages: 547
Publication
First Author: Hu HJ
Year: 2022
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: PLK1 promotes cholesterol efflux and alleviates atherosclerosis by up-regulating ABCA1 and ABCG1 expression via the AMPK/PPARγ/LXRα pathway.
Volume: 1867
Issue: 12
Pages: 159221
Publication  
First Author: Meng M
Year: 2024
Journal: Metabolism
Title: Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.
Volume: 152
Pages: 155784
Publication
First Author: Aicher WK
Year: 1992
Journal: Int Immunol
Title: Effects of the lpr/lpr mutation on T and B cell populations in the lamina propria of the small intestine, a mucosal effector site.
Volume: 4
Issue: 9
Pages: 959-68
Publication
First Author: Langner CA
Year: 1989
Journal: J Biol Chem
Title: The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities.
Volume: 264
Issue: 14
Pages: 7994-8003
Publication
First Author: Davis RC
Year: 1990
Journal: J Biol Chem
Title: Combined lipase deficiency in the mouse. Evidence of impaired lipase processing and secretion.
Volume: 265
Issue: 29
Pages: 17960-6
Publication
First Author: Schultz CJ
Year: 2000
Journal: J Lipid Res
Title: Adrenal and liver in normal and cld/cld mice synthesize and secrete hepatic lipase, but the lipase is inactive in cld/cld mice.
Volume: 41
Issue: 2
Pages: 214-25
Publication
First Author: Simpson SJ
Year: 1995
Journal: Eur J Immunol
Title: Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis.
Volume: 25
Issue: 9
Pages: 2618-25
Publication
First Author: Davidson NJ
Year: 1996
Journal: J Exp Med
Title: T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
Volume: 184
Issue: 1
Pages: 241-51
Publication
First Author: Greve HJ
Year: 2020
Journal: J Neuroinflammation
Title: Diesel exhaust impairs TREM2 to dysregulate neuroinflammation.
Volume: 17
Issue: 1
Pages: 351
Publication
First Author: Qiao L
Year: 2020
Journal: Diabetes
Title: Obesity Reduces Maternal Blood Triglyceride Concentrations by Reducing Angiopoietin-Like Protein 4 Expression in Mice.
Volume: 69
Issue: 6
Pages: 1100-1109
Publication
First Author: Carmona MC
Year: 2005
Journal: Biochem J
Title: Defective thermoregulation, impaired lipid metabolism, but preserved adrenergic induction of gene expression in brown fat of mice lacking C/EBPbeta.
Volume: 389
Issue: Pt 1
Pages: 47-56
Publication
First Author: Kako Y
Year: 1999
Journal: J Lipid Res
Title: Streptozotocin-induced diabetes in human apolipoprotein B transgenic mice. Effects on lipoproteins and atherosclerosis.
Volume: 40
Issue: 12
Pages: 2185-94
Publication
First Author: Dijk W
Year: 2018
Journal: J Biol Chem
Title: Angiopoietin-like 4 promotes the intracellular cleavage of lipoprotein lipase by PCSK3/furin in adipocytes.
Volume: 293
Issue: 36
Pages: 14134-14145
Publication  
First Author: Cleland NRW
Year: 2024
Journal: Brain Res
Title: Altered metabolism and DAM-signatures in female brains and microglia with aging.
Volume: 1829
Pages: 148772
Publication
First Author: Aalto-Setälä K
Year: 1996
Journal: J Lipid Res
Title: Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice.
Volume: 37
Issue: 8
Pages: 1802-11
Publication
First Author: Hwang M
Year: 2022
Journal: J Neuroinflammation
Title: Trem2 deficiency impairs recovery and phagocytosis and dysregulates myeloid gene expression during virus-induced demyelination.
Volume: 19
Issue: 1
Pages: 267
Publication
First Author: Heerwagen MJ
Year: 2013
Journal: PLoS One
Title: Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice.
Volume: 8
Issue: 6
Pages: e67791
Publication
First Author: Vomhof-DeKrey EE
Year: 2019
Journal: PLoS One
Title: Schlafen 3 knockout mice display gender-specific differences in weight gain, food efficiency, and expression of markers of intestinal epithelial differentiation, metabolism, and immune cell function.
Volume: 14
Issue: 7
Pages: e0219267
Publication  
First Author: Lin X
Year: 2023
Journal: Front Cell Dev Biol
Title: Expression of non-phosphorylatable S5A-L-plastin exerts phenotypes distinct from L-plastin deficiency during podosome formation and phagocytosis.
Volume: 11
Pages: 1020091
Publication
First Author: Chi X
Year: 2017
Journal: Mol Metab
Title: ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase.
Volume: 6
Issue: 10
Pages: 1137-1149
Publication
First Author: Ashraf Y
Year: 2020
Journal: FEBS J
Title: Proprotein convertase 7 (PCSK7) reduces apoA-V levels.
Volume: 287
Issue: 16
Pages: 3565-3578
Publication
First Author: Park EI
Year: 1997
Journal: J Nutr
Title: Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases.
Volume: 127
Issue: 4
Pages: 566-73
Publication
First Author: Bonnet M
Year: 2000
Journal: J Nutr
Title: Lipoprotein lipase activity and mRNA are up-regulated by refeeding in adipose tissue and cardiac muscle of sheep.
Volume: 130
Issue: 4
Pages: 749-56
Publication
First Author: Rebuffé-Scrive M
Year: 1993
Journal: Metabolism
Title: Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus.
Volume: 42
Issue: 11
Pages: 1405-9
Publication
First Author: Esenabhalu VE
Year: 2002
Journal: Br J Pharmacol
Title: Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice.
Volume: 135
Issue: 1
Pages: 143-54
Publication
First Author: Xie W
Year: 2016
Journal: PLoS One
Title: MicroRNA-27 Prevents Atherosclerosis by Suppressing Lipoprotein Lipase-Induced Lipid Accumulation and Inflammatory Response in Apolipoprotein E Knockout Mice.
Volume: 11
Issue: 6
Pages: e0157085
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
Protein Domain
Type: Homologous_superfamily
Description: This superfamily represents the fold comprising the seven β-strands found in the catalytic domain of Class II of aminoacyl-tRNA synthetases (aaRS), the lipoyl protein ligase (LPL) and the biotinyl protein ligase (BPL). Interestingly, Class II of aaRSs has a two-step reaction mechanism analogous to that of BPL. It first catalyses the ATP-dependent formation of an aminoacyl-AMP intermediate and then transfer the activated aminoacyl moiety to an acceptor tRNA [].The aminoacyl-tRNA synthetases (also known as aminoacyl-tRNA ligases) catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction [, ]. These proteins differ widely in size and oligomeric state, and have limited sequence homology []. The 20 aminoacyl-tRNA synthetases are divided into two classes, I and II. Class I aminoacyl-tRNA synthetases contain a characteristic Rossman fold catalytic domain and are mostly monomeric []. Class II aminoacyl-tRNA synthetases share an antiparallel β-sheet fold flanked by α-helices [], and are mostly dimeric or multimeric, containing at least three conserved regions [, , ]. However, tRNA binding involves an α-helical structure that is conserved between class I and class II synthetases. In reactions catalysed by the class I aminoacyl-tRNA synthetases, the aminoacyl group is coupled to the 2'-hydroxyl of the tRNA, while, in class II reactions, the 3'-hydroxyl site is preferred. The synthetases specific for arginine, cysteine, glutamic acid, glutamine, isoleucine, leucine, methionine, tyrosine, tryptophan, valine, and some lysine synthetases (non-eukaryotic group) belong to class I synthetases. The synthetases specific for alanine, asparagine, aspartic acid, glycine, histidine, phenylalanine, proline, serine, threonine, and some lysine synthetases (non-archaeal group), belong to class-II synthetases. Based on their mode of binding to the tRNA acceptor stem, both classes of tRNA synthetases have been subdivided into three subclasses, designated 1a, 1b, 1c and 2a, 2b, 2c [].BPLs and LPLs are evolutionarily related protein families, with a homologous catalytic module (seven-stranded mixed β-sheet on one side and four α-helices on the other side) that must have evolved from a common ancestor [, ]. Amino acid sequence conservation between the catalytic modules of biotinyl protein ligases (BPLs) and lipoyl protein ligases (LPLs) is very low, and mainly affects residues that are important for the scaffold of the structure, such as those contributing to the hydrophobic core. Despite the poor overall sequence similarity, a single lysine residue is strictly conserved in all LPL and BPL sequences. This lysine residue is likely to bind specifically to the carbonyl oxygen of the carboxyl group of biotin or at the end of the hydrogen-carbon tail of the lipoyl moiety [].
Publication  
First Author: Tucker AE
Year: 2022
Journal: Front Behav Neurosci
Title: Chronic Ethanol Causes Persistent Increases in Alzheimer's Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment.
Volume: 16
Pages: 886634
Publication
First Author: Aalto-Setälä K
Year: 1992
Journal: J Clin Invest
Title: Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
Volume: 90
Issue: 5
Pages: 1889-900
Publication
First Author: Adachi H
Year: 1995
Journal: J Endocrinol
Title: Involvement of epidermal growth factor in inducing adiposity of age female mice.
Volume: 146
Issue: 3
Pages: 381-93
Publication
First Author: Jensen DR
Year: 1997
Journal: Am J Physiol
Title: Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase.
Volume: 273
Issue: 2 Pt 2
Pages: R683-9
Protein
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
Publication
First Author: Reche PA
Year: 2000
Journal: Protein Sci
Title: Lipoylating and biotinylating enzymes contain a homologous catalytic module.
Volume: 9
Issue: 10
Pages: 1922-9
Publication
First Author: Bagautdinov B
Year: 2005
Journal: J Mol Biol
Title: Crystal structures of biotin protein ligase from Pyrococcus horikoshii OT3 and its complexes: structural basis of biotin activation.
Volume: 353
Issue: 2
Pages: 322-33
Publication  
First Author: Park JW
Year: 1996
Journal: Biochem J
Title: Brefeldin A enables synthesis of active lipoprotein lipase in cld/cld and castanospermine-treated mouse brown adipocytes via translocation of Golgi components to endoplasmic reticulum.
Volume: 317 ( Pt 1)
Pages: 125-34
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 869  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false