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Search results 1001 to 1100 out of 3345 for Myb

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Type Details Score
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
11597504 | -
First Author: Stracke R
Year: 2001
Journal: Curr Opin Plant Biol
Title: The R2R3-MYB gene family in Arabidopsis thaliana.
Volume: 4
Issue: 5
Pages: 447-56
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Protein Domain
IPR017930 | Myb_dom
Type: Domain
Description: The myb-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of approximately 55 amino acids, typically occurring in a tandem repeat in eukaryotic transcription factors. The domain is named after the retroviral oncogene v-myb, and its cellular counterpart c-myb, which encode nuclear DNA-binding proteins that specifically recognise the sequence YAAC(G/T)G [, ]. Myb proteins contain three tandem repeats of 51 to 53 amino acids, termed R1, R2 and R3. This repeat region is involved in DNA-binding and R2 and R3 bind directly to the DNA major groove. The major part of the first repeat is missing in retroviral v-Myb sequences and in plant myb-related (R2R3) proteins []. A single myb-type HTH DNA-binding domain occurs in TRF1 and TRF2.The 3D-structure of the myb-type HTH domain forms three α-helices []. The second and third helices connected via a turn comprisethe helix-turn-helix motif. Helix 3 is termed the recognition helix as itbinds the DNA major groove, like in other HTHs.
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Protein Coding Gene
MGI:1344415 | Dmtf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Gene
321277 | mybbp1a
Type: gene
Organism: zebrafish
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Publication
22874877 | J:193662
First Author: Pattabiraman DR
Year: 2013
Journal: Leukemia
Title: Role and potential for therapeutic targeting of MYB in leukemia.
Volume: 27
Issue: 2
Pages: 269-77
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Publication
1886709 | J:11401
First Author: Sopchak L
Year: 1991
Journal: Oncogene
Title: Loss of myb expression in an aggressive SJL/J B-cell lymphoma.
Volume: 6
Issue: 8
Pages: 1335-8
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Publication
1544326 | J:392
First Author: Ma NS
Year: 1992
Journal: Cytogenet Cell Genet
Title: Regional localization of the owl monkey MYB and OMLA gene loci.
Volume: 59
Issue: 4
Pages: 288-9
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Publication
23056166 | J:191942
First Author: Mori S
Year: 2012
Journal: PLoS One
Title: Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.
Volume: 7
Issue: 10
Pages: e39723
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Publication
- | J:80626
   
First Author: Lederer M
Year: 2002
Journal: GenBank Submission
Title: Mus musculus Myb protein P42POP mRNA, complete cds
Pages: AF364868
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Publication
19102728 | -
First Author: Hofr C
Year: 2009
Journal: Biochem J
Title: Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics.
Volume: 419
Issue: 1
Pages: 221-8, 2 p following 228
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Protein Domain
IPR044597 | SMH1-6
Type: Family
Description: This entry includes single myb histone 1-6 (SMH1-6) from maize and telomere repeat-binding factor 1-5 (TRB1-5) from Arabidopsis. They are a group of proteins that bind telomere DNA repeats [, ]. This entry also includes uncharacterised proteins from fungi.
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Protein Coding Gene
MGI:106181 | Mybbp1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
3121304 | -
First Author: Peters CW
Year: 1987
Journal: EMBO J
Title: Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain.
Volume: 6
Issue: 10
Pages: 3085-90
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Publication
14744933 | J:88279
First Author: Fan M
Year: 2004
Journal: Genes Dev
Title: Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.
Volume: 18
Issue: 3
Pages: 278-89
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Protein Domain
IPR015010 | Rap1_Myb_dom
Type: Domain
Description: Rap1 Myb adopts a canonical three-helix bundle tertiary structure, with the second and third helices forming a helix-turn-helix variant motif. The function is unclear but it may either interact with DNA via an adaptor protein or it may be only involved in protein-protein interactions [].
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Protein Domain
IPR045026 | LIMYB
Type: Family
Description: L10-interacting MYB domain-containing protein (LIMYB) is a transcriptional repressor that associates with ribosomal protein promoters []. It interacts with NIK1, a leucine-rich repeat receptor-like kinase (LRR-RLK), the virulence target of the begomovirus nuclear shuttle protein, leading to global translation suppression as an antiviral immunity strategy in plants [].
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Publication
35081355 | J:324793
First Author: Zhang K
Year: 2022
Journal: Cell Rep
Title: The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I.
Volume: 38
Issue: 4
Pages: 110289
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Publication
22157820 | J:181759
First Author: Stadhouders R
Year: 2012
Journal: EMBO J
Title: Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development.
Volume: 31
Issue: 4
Pages: 986-99
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Publication
29316427 | J:253748
First Author: Xu Y
Year: 2018
Journal: Cancer Cell
Title: A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia.
Volume: 33
Issue: 1
Pages: 13-28.e8
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Publication
10380886 | J:55885
First Author: Davies J
Year: 1999
Journal: Oncogene
Title: Cooperation of Myb and Myc proteins in T cell lymphomagenesis.
Volume: 18
Issue: 24
Pages: 3643-7
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Publication
10985773 | -
First Author: Misra S
Year: 2000
Journal: Biochemistry
Title: Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes.
Volume: 39
Issue: 37
Pages: 11282-90
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Publication
9419227 | J:44816
First Author: Rosinski JA
Year: 1998
Journal: J Mol Evol
Title: Molecular evolution of the Myb family of transcription factors: evidence for polyphyletic origin.
Volume: 46
Issue: 1
Pages: 74-83
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Publication
3608990 | -
First Author: Watson RJ
Year: 1987
Journal: EMBO J
Title: Multiple c-myb transcript cap sites are variously utilized in cells of mouse haemopoietic origin.
Volume: 6
Issue: 6
Pages: 1643-51
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Publication
3014527 | -
First Author: Weinstein Y
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line.
Volume: 83
Issue: 14
Pages: 5010-4
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Publication
2670562 | -
First Author: Gonda TJ
Year: 1989
Journal: EMBO J
Title: Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro.
Volume: 8
Issue: 6
Pages: 1777-83
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Publication
8408047 | -
First Author: Nomura T
Year: 1993
Journal: J Biol Chem
Title: Negative autoregulation of c-Myb activity by homodimer formation through the leucine zipper.
Volume: 268
Issue: 29
Pages: 21914-23
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Publication
1631139 | -
First Author: Ogata K
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Solution structure of a DNA-binding unit of Myb: a helix-turn-helix-related motif with conserved tryptophans forming a hydrophobic core.
Volume: 89
Issue: 14
Pages: 6428-32
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Publication
8365401 | -
First Author: Jamin N
Year: 1993
Journal: Eur J Biochem
Title: Secondary structure of the DNA-binding domain of the c-Myb oncoprotein in solution. A multidimensional double and triple heteronuclear NMR study.
Volume: 216
Issue: 1
Pages: 147-54
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Publication
7796266 | -
First Author: Ogata K
Year: 1995
Journal: Nat Struct Biol
Title: Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Volume: 2
Issue: 4
Pages: 309-20
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Publication
8942977 | -
First Author: Furukawa K
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Volume: 93
Issue: 24
Pages: 13583-8
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Protein Coding Gene
MGI:3045322 | Dmtf1l
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
7954830 | J:21600
First Author: Ogata K
Year: 1994
Journal: Cell
Title: Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices.
Volume: 79
Issue: 4
Pages: 639-48
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Publication
12621023 | J:83601
First Author: Hinkley CS
Year: 2003
Journal: J Biol Chem
Title: The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.
Volume: 278
Issue: 20
Pages: 18649-57
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Publication
6672765 | J:7392
First Author: McBride OW
Year: 1983
Journal: Nucleic Acids Res
Title: Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells.
Volume: 11
Issue: 23
Pages: 8221-36
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Publication
7630637 | J:101798
First Author: Press RD
Year: 1995
Journal: Oncogene
Title: Induction of B cell lymphomas by overexpression of a Myb oncogene truncated at either terminus.
Volume: 11
Issue: 3
Pages: 525-35
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Gene
475217 | DMTF1
Type: gene
Organism: dog, domestic
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Gene
489568 | MYSM1
Type: gene
Organism: dog, domestic
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Gene
612218 | MYPOP
Type: gene
Organism: dog, domestic
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Gene
456892 | MYSM1
Type: gene
Organism: chimpanzee
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Gene
501612 | Dmtf1l
Type: gene
Organism: rat
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Gene
468924 | MYPOP
Type: gene
Organism: chimpanzee
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Gene
472434 | DMTF1
Type: gene
Organism: chimpanzee
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Gene
515332 | MYSM1
Type: gene
Organism: cattle
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Gene
520267 | MYPOP
Type: gene
Organism: cattle
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Gene
539676 | DMTF1
Type: gene
Organism: cattle
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Gene
418646 | DMTF1
Type: gene
Organism: chicken
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Gene
424671 | MYSM1
Type: gene
Organism: chicken
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Gene
706292 | DMTF1
Type: gene
Organism: macaque, rhesus
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Gene
716780 | MYPOP
Type: gene
Organism: macaque, rhesus
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Gene
718013 | MYSM1
Type: gene
Organism: macaque, rhesus
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Gene
100493762 | dmtf1
Type: gene
Organism: frog, western clawed
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Gene
100126685 | mysm1
Type: gene
Organism: frog, western clawed
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Gene
108695325 | mybl1.S
Type: gene
Organism: frog, African clawed
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Gene
108704610 | mybl2.L
Type: gene
Organism: frog, African clawed
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Gene
108708354 | mybbp1a.L
Type: gene
Organism: frog, African clawed
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Gene
108716152 | myb.L
Type: gene
Organism: frog, African clawed
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Gene
397697 | mybl1.L
Type: gene
Organism: frog, African clawed
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Gene
398039 | myb.S
Type: gene
Organism: frog, African clawed
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Gene
398085 | mybl2.S
Type: gene
Organism: frog, African clawed
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Gene
779416 | mysm1.L
Type: gene
Organism: frog, African clawed
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Publication
22039255 | J:179063
First Author: Kobayashi M
Year: 2011
Journal: Blood
Title: Regulation of murine hematopoietic stem cell quiescence by Dmtf1.
Volume: 118
Issue: 25
Pages: 6562-71
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Publication
25723764 | -
 
First Author: Medici A
Year: 2015
Journal: Nat Commun
Title: AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip.
Volume: 6
Pages: 6274
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Publication
22545134 | -
First Author: Wu C
Year: 2012
Journal: PLoS One
Title: HRS1 acts as a negative regulator of abscisic acid signaling to promote timely germination of Arabidopsis seeds.
Volume: 7
Issue: 4
Pages: e35764
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Publication
25132385 | -
First Author: Yan Y
Year: 2014
Journal: Dev Cell
Title: A MYB-domain protein EFM mediates flowering responses to environmental cues in Arabidopsis.
Volume: 30
Issue: 4
Pages: 437-48
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Protein Domain
IPR044787 | HRS1-like
Type: Family
Description: This entry represents a group of plant Myb family transcription factors, including HHO1-6, HRS1 and EFM from Arabidopsis. HRS1 represses primary root development in response to phosphate deficiency conditions, only when nitrate is present []. It is also required for suppressing abscisic acid (ABA) signalling in germinating embryo axis, which promotes the timely germination of seeds []. EFM functions as a flowering repressor, directly repressing FT expression in a dosage-dependent manner in the leaf vasculature [].
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Publication
11290610 | J:68804
First Author: Lutz PG
Year: 2001
Journal: Blood
Title: Myeloblastin is an Myb target gene: mechanisms of regulation in myeloid leukemia cells growth-arrested by retinoic acid.
Volume: 97
Issue: 8
Pages: 2449-56
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Publication
38463444 | J:352220
First Author: Almeida A
Year: 2024
Journal: Hemasphere
Title: Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia.
Volume: 8
Issue: 3
Pages: e51
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Publication
10652136 | -
First Author: Rose A
Year: 1999
Journal: Plant J
Title: The tomato I-box binding factor LeMYBI is a member of a novel class of myb-like proteins.
Volume: 20
Issue: 6
Pages: 641-52
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Protein Domain
IPR006447 | Myb_dom_plants
Type: Domain
Description: This DNA-binding domain is restricted to (but common in) plant proteins, many of which also contain a response regulator domain. The domain appears related to the Myb-like DNA-binding domain [, ].
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Protein
O88746-2
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
A0A1D5RL90
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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Protein
A0A1D5RM45
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
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Protein
A0A1D5RM84
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
A0A1D5RM51
Organism: Mus musculus/domesticus
Length: 25  
Fragment?: true
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Protein
A0A1D5RM12
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: false
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Publication
21062982 | J:166854
First Author: Taneja P
Year: 2010
Journal: Cancer Res
Title: Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.
Volume: 70
Issue: 22
Pages: 9084-94
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Publication
15611048 | -
First Author: Puertollano R
Year: 2005
Journal: J Biol Chem
Title: Interactions of TOM1L1 with the multivesicular body sorting machinery.
Volume: 280
Issue: 10
Pages: 9258-64
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Publication
14563850 | J:148073
First Author: Yamakami M
Year: 2003
Journal: J Biol Chem
Title: Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin.
Volume: 278
Issue: 52
Pages: 52865-72
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Protein Domain
IPR014645 | TOM1
Type: Family
Description: Tom1 (target of Myb 1) and its related proteins (Tom1L1 and Tom1L2) constitute a protein family and share an N-terminal VHS (Vps27p/Hrs/Stam) domain followed by a GAT (GGA and Tom1) domain.VHS domains are found at the N termini of select proteins involved in intracellular membrane trafficking and are often localized to membranes. The three dimensional structure of human TOM1 VHS domain reveals eight helices arranged in a superhelix. The surface of the domain has two main features: (1) a basic patch on one side due to several conserved positively charged residues on helix 3 and (2) a negatively charged ridge on the opposite side, formed by residues on helix 2 []. The basic patch is thought to mediate membrane binding.It was demonstrated that the GAT domain of both Tom1 and Tom1L1 binds ubiquitin, suggesting that these proteins might participate in the sorting of ubiquitinated proteins into multivesicular bodies (MVB) []. Moreover, Tom1L1 interacts with members of the MVB sorting machinery. Specifically, the VHS domain of Tom1L1 interacts with Hrs (hepatocyte growth factor-regulated tyrosine kinase substrate), whereas a PTAP motif, located between the VHS and GAT domains of Tom1L1, is responsible for binding to TSG101 (tumour susceptibility gene 101). Myc epitope-tagged Tom1L1 is recruited to endosomes following Hrs expression. In addition, Tom1L1 possesses several tyrosine motifs at the C-terminal region that mediate interactions with members of the Src family kinases and other signalling proteins such as Grb2 and p85. Expression of a constitutively active form of Fyn kinase promotes the recruitment of Tom1L1 to enlarged endosomes. It is proposed that Tom1L1 could act as an intermediary between the signalling and degradative pathways [].Over expression of Tom1 suppresses activation of the transcription factors NF-kappaB and AP-1, induced by either IL-1beta or tumour necrosis factor (TNF)-alpha, and the VHS domain of Tom1 is indispensable for this suppressive activity. This suggests that Tom1 is a common negative regulator of signalling pathways induced by IL-1beta and TNF-alpha [].
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Publication
1979025 | J:10853
First Author: Nguyen J
Year: 1990
Journal: Cytogenet Cell Genet
Title: Genetic linkage group (ARG1-D6S33-MYB) on chromosome 6q containing the arginase-1 and MYB genes.
Volume: 54
Issue: 1-2
Pages: 95-6
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Publication
25707794 | -
First Author: Zorzatto C
Year: 2015
Journal: Nature
Title: NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism.
Volume: 520
Issue: 7549
Pages: 679-82
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Gene
302774 | Dmtf1l2
Type: gene
Organism: rat
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Gene
100494087 | mypopl1
Type: gene
Organism: frog, western clawed
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Gene
108705291 | mypopl1.L
Type: gene
Organism: frog, African clawed
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Gene
108711211 | dmtf1.L
Type: gene
Organism: frog, African clawed
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Gene
108713055 | dmtf1.S
Type: gene
Organism: frog, African clawed
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Gene
108718342 | mypopl1.S
Type: gene
Organism: frog, African clawed
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Publication
10898794 | J:63444
First Author: Inoue K
Year: 2000
Journal: Genes Dev
Title: Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.
Volume: 14
Issue: 14
Pages: 1797-809
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Protein Coding Gene
MGI:1922910 | Lin37
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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