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Hits by Strain

Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele  
Name: solute carrier family 12, member 2; endonuclease-mediated mutation 1, Eric Delpire
Allele Type: Endonuclease-mediated
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Cat4/Cat4<+>
Background: involves: 101 * C3H
Zygosity: ht
Has Mutant Allele: true
MP Term
MP Term
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Espl1/Espl1<+> Meox2/Meox2<+>
Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Espl1/Espl1<+> Trp53/Trp53<+>
Background: B6.129-Trp53 Espl1
Zygosity: cx
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Ccr2/Ccr2
Background: B6.129P2-Ccr2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Abca4/Abca4 Rdh8/Rdh8
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Gene
Type: gene
Organism: human
DO Term
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Pelton TA
Year: 2002
Journal: J Cell Sci
Title: Transient pluripotent cell populations during primitive ectoderm formation: correlation of in vivo and in vitro pluripotent cell development.
Volume: 115
Issue: Pt 2
Pages: 329-39
GO Term
GO Term
GO Term
GO Term
GO Term
GO Term
GO Term
GXD Expression  
Probe: MGI:3688114
Assay Type: Immunohistochemistry
Annotation Date: 2006-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688137
Age: embryonic day 19.5
Note: Expression was detected in preameloblast/ameloblast cells and signal accumulated at the basal and apical pole of the cell membrane. The intensity of the signal decreased at the tip of the dental cusps and in cervical loop direction.
Specimen Label: 4E
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3688114
Assay Type: Immunohistochemistry
Annotation Date: 2006-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688137
Age: embryonic day 19.5
Note: Expression was detected in preameloblast/ameloblast cells and signal accumulated at the basal and apical pole of the cell membrane. The intensity of the signal decreased at the tip of the dental cusps and in cervical loop direction.
Specimen Label: 4F
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3688114
Assay Type: Immunohistochemistry
Annotation Date: 2006-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1829626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3688137
Age: embryonic day 19.5
Note: Expression was detected in preameloblast/ameloblast cells and signal accumulated at the basal and apical pole of the cell membrane. The intensity of the signal decreased at the tip of the dental cusps and in cervical loop direction.
Specimen Label: 4G
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:5449269
Assay Type: RNA in situ
Annotation Date: 2013-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Scattered
Stage: TS28
Assay Id: MGI:5449376
Age: embryonic day 6.0
Image: 2G/H
Note: Expression in scattered cells distal to ventral pole of egg cylinder and in few cells beside embryo. High expression in some cells near giant trophoblast cells. Extends mesometrially to cells around ectoplacental cone and underlying uterine epithelium.
Specimen Label: 2G/H
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:5449269
Assay Type: RNA in situ
Annotation Date: 2013-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5449376
Age: embryonic day 6.5
Image: 3A/B
Note: High expression in clusters of cells beside embryo, next to giant trophoblast cells. Moderate expression in small decidual cells of implantation zone next to distal tip of embryo. Expression near ventral pole of embryo and beside embryo.
Specimen Label: 3A/B
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:2450111
Assay Type: Immunohistochemistry
Annotation Date: 2003-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:2450133
Age: embryonic day 2.5
Note: Expression in the cytocortex was detected in the apical microvillous pole on the outer surface of each blastomere in 57% of the embryos but absent from the nascent apicolateral tight junctions site.
Specimen Label: Not Shown
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3706964
Assay Type: Immunohistochemistry
Annotation Date: 2007-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3518328
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:3706973
Age: postnatal adult
Note: Expression is concentrated at the cell layer lining the ventricles, coinciding with the surface of the ependymal cell layer. The pattern is discontinuous, coinciding with the apical pole of individual ependymal cells.
Specimen Label: Adult
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:31382
Assay Type: RNA in situ
Annotation Date: 2010-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4838635
Age: embryonic day 12.5
Note: Expression in distinct bands of cells in the telencephalon. The more dorsal band is wider and extends caudally from the anlage of the olfactory bulb to the caudal pole of the telencephalon.
Specimen Label: 3b
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4848131
Assay Type: Immunohistochemistry
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800325
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:4849228
Age: embryonic day 17.5
Note: Expression is present in the early proximal tubule, although it is not present in the presumptive S1 segment (the early proximal tubule at the urinary pole of the renal corpuscle).
Specimen Label: 3i
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:5001436
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5541990
Age: embryonic day 15.5
Image: GUDMAP:9128
Note: distal expression; expression restricted to a subset of the early proximal. Expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
Specimen Label: GUDMAP:9128
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5001076
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5541633
Age: embryonic day 15.5
Image: GUDMAP:9136
Note: distal expression; expression restricted to a subset of the early proximal. Expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
Specimen Label: GUDMAP:9136
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5001436
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3154223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5541990
Age: embryonic day 15.5
Image: GUDMAP:9128
Note: distal expression; expression restricted to a subset of the early proximal; expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
Specimen Label: GUDMAP:9128
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5001076
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3154223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5541633
Age: embryonic day 15.5
Image: GUDMAP:9136
Note: distal expression; expression restricted to a subset of the early proximal; expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
Specimen Label: GUDMAP:9136
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5001390
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3154223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541944
Age: embryonic day 15.5
Image: GUDMAP:9180
Note: strong expression in a subset of early proximal; moderate expression in the first segment of early proximal at the urinary pole of maturing renal corpuscles; expression in tubules adjacent to the immature loop of Henle
Specimen Label: GUDMAP:9180
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2450111
Assay Type: Immunohistochemistry
Annotation Date: 2003-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:2450133
Age: embryonic day 2.5
Image: 2B
Note: Expression in the cytocortex was detected in the apical microvillous pole on the outer surface of each blastomere in 85% of the embryos but absent from the nascent apicolateral tight junctions site.
Specimen Label: 2B
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:2450111
Assay Type: Immunohistochemistry
Annotation Date: 2003-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:2450133
Age: embryonic day 3.0
Image: 2C
Note: Expression in the cytocortex was in the apical microvillous pole in outer blastomeres of the trophectoderm lineage of 67% of embryos. Faint zonular or discontinuous staining was in the forming tight junction sites of each blastomere in 75% of embryos.
Specimen Label: 2C
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:5437988
Assay Type: Immunohistochemistry
Annotation Date: 2012-10-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Scattered
Stage: TS20
Assay Id: MGI:5437996
Age: embryonic day 12.3
Image: 2g
Note: In this gonad expressing cells are present at the anterior pole (pictured), as well as the posterior pole. This was the only gonad at this stage observed to have this staining pattern.
Specimen Label: 2g
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:461764
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754023
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:4827116
Age: embryonic day 14.5
Image: 6C - Pde10a
Note: There is a strong signal at the anterior pole of the thalamus (showing a sharp edge of its expression domain at the limit with the prethalamus); expression levels become progressively weaker towards the caudal pole.
Specimen Label: 6C - Pde10a
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3688116
Assay Type: Immunohistochemistry
Annotation Date: 2006-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1792222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3688139
Age: embryonic day 14.5
Note: Expression signal was distributed at cell-cell contact of the inner and outer dental epithelium of the lingual side, whereas in the labial side the labeling accumulated at the basal pole of the cells.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3688116
Assay Type: Immunohistochemistry
Annotation Date: 2006-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1792222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3688139
Age: embryonic day 14.5
Note: Expression signal was distributed at cell-cell contact of the inner and outer dental epithelium of the lingual side, whereas in the labial side the labeling accumulated at the basal pole of the cells.
Specimen Label: 5C
Detected: true
Specimen Num: 3
Publication
First Author: Koumangoye R
Year: 2018
Journal: Am J Physiol Cell Physiol
Title: Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells.
Volume: 315
Issue: 2
Pages: C258-C276
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Omer S
Year: 2020
Journal: J Cell Physiol
Title: A mutation in the Na-K-2Cl cotransporter-1 leads to changes in cellular metabolism.
Volume: 235
Issue: 10
Pages: 7239-7250
Publication
First Author: Koumangoye R
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation.
Volume: 9
Issue: 2
Pages: 239-255
Publication
First Author: Koumangoye R
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane.
Volume: 316
Issue: 4
Pages: C545-C558
Publication
First Author: Perry JSA
Year: 2019
Journal: Nat Cell Biol
Title: Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Volume: 21
Issue: 12
Pages: 1532-1543
Genotype
Symbol: Slc12a2/Slc12a2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Slc12a2/Slc12a2
Background: involves: C57BL/6J * DBA/2J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Slc12a2/Slc12a2
Background: B6.Cg-Slc12a2
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Slc12a2/Slc12a2<+>
Background: involves: C57BL/6J * DBA/2J
Zygosity: ht
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GO Term
GO Term
GO Term
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Sundin BA
Year: 2004
Journal: Yeast
Title: Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.
Volume: 21
Issue: 9
Pages: 793-800
Protein Domain
Type: Family
Description: This family includes nuclear envelope protein YPR174C and NAP1-binding protein (NBP1). Both proteins bind to the nuclear membrane. NBP1 has been shown in Saccharomyces cerevisiae to function in spindle pole body duplication []and YPR174C may be involved in the connection of the spindle pole body to the nuclear envelope [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory