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Search results 1001 to 1100 out of 2837 for Prox1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660552
Age: embryonic day 12.5
Image: 1E
Note: Expressed in jugular lymph sacs endothelial cells.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660552
Age: embryonic day 12.5
Image: 1F
Note: Expressed in jugular lymph sacs endothelial cells.
Specimen Label: 1F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: 1G
Note: Expressed in the trunk lymphatics.
Specimen Label: 1G
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: 1H
Note: Expressed in the lung lymphatics.
Specimen Label: 1H
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: 1I
Note: Expressed in the dermal lymphatics.
Specimen Label: 1I
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: 2A
Note: Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Nfatc1 and Flt4.
Specimen Label: 2A
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: 2B
Note: Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Nfatc1.
Specimen Label: 2B
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: 2C
Note: Coexpressed with Flt4.
Specimen Label: 2C
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: 2D
Specimen Label: 2D
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660552
Age: embryonic day 12.5
Image: S1B/C
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen Label: S1B/C
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660552
Age: embryonic day 12.5
Image: S1D
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen Label: S1D
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660552
Age: embryonic day 12.5
Image: S1E
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells.
Specimen Label: S1E
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: S1F
Note: Expressed in the dermal lymphatics.
Specimen Label: S1F
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: S1G
Note: Expressed in the dermal lymphatics.
Specimen Label: S1G
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: S1H
Note: Expressed in the pulmonary lymphatics.
Specimen Label: S1H
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660552
Age: embryonic day 14.5
Image: S1I
Note: Expressed in the pulmonary lymphatics.
Specimen Label: S1I
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: S2A
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Specimen Label: S2A
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5660388
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660552
Age: embryonic day 11.5
Image: S2B
Note: Expressed in endothelial cells sprouting from the cardinal vein in organized lymph sacs and dispersed single cell clusters. Coexpressed with Pdpn.
Specimen Label: S2B
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1824822
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Authors state no lymphatic vessels and capillaries were seen in homozygous littermates.
Specimen Label: 4C
Detected: false
Specimen Num: 13
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1824821
Stage: TS21
Assay Id: MGI:6201326
Age: embryonic day 13.5
Note: No lymphatic vessels or capillaries were observed in same region of Prox1-/- embryos. Authors state lymph sacs, networks of lymphatic vessels, and superficial lymphatic capillaries were not developed in nullizygous embryos at this stage.
Specimen Label: 5H
Detected: false
Specimen Num: 21
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Expression in lymphatic cells around the esophagus, trachea and pulmonary bronchi.
Specimen Label: 7A
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1824822
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Authors report no expression in trachea, esophagus and lungs.
Specimen Label: 7B
Detected: false
Specimen Num: 23
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Expression in lymphatic vessels in the lung.v
Specimen Label: 7C +/-
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1824822
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Authors report no expression in trachea, esophagus and lungs.
Specimen Label: 7C -/-
Detected: false
Specimen Num: 25
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Expression in lymphatic vessels in the mesenteries of intestines.
Specimen Label: 7D
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1824822
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: No expression in the mesenteries of intestines.
Specimen Label: 7E
Detected: false
Specimen Num: 27
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6201326
Age: embryonic day 14.5
Note: Expression in jugular and perimesonephric regions. Expression in jugular and retroperitoneal lymph sacs.
Specimen Label: 1E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6201326
Age: embryonic day 15.5
Note: Expression in larger lymphatic vessels in deeper plexus.
Specimen Label: 1F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 2D
Note: Expression in lymphatic endothelial cell precursors delaminated from the cardinal vein.
Specimen Label: 2D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 2E
Note: Expression in pre-lymphatic clusters (PLC) at level of forelimb bud where cardinal vein diverts to form a lateral branch.
Specimen Label: 2E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 2F
Note: Expression in pre-lymphatic clusters (PLC) at level of forelimb bud where cardinal vein diverts to form a lateral branch.
Specimen Label: 2F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 3D
Note: Authors report lymph sacs were observed immediately adjacent to pre-lymphatic clusters.
Specimen Label: 3D
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 3E
Note: Authors report lymph sacs were observed immediately adjacent to pre-lymphatic clusters.
Specimen Label: 3E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6283364
Age: embryonic day 11.5
Image: 3F
Note: Authors report lymph sacs were observed immediately adjacent to pre-lymphatic clusters.
Specimen Label: 3F
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6283364
Age: embryonic day 10.5
Image: 5E/G
Note: Expression in lymph sacs maintaining a stalklike connection to the cardinal vein at these stages of development. Expression in lymphatic endothelial cells sprouting in a dorso-lateral direction towards the embryo periphery.
Specimen Label: 5E/G
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6303621
Age: embryonic day 11.5
Image: 2B
Note: Authors report expression near lymphatic endothelial cell (LEC) progenitors.
Specimen Label: 2B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6313605
Age: embryonic day 14.5
Image: 4A
Note: Expression was detected in lymphatic endothelial cells.
Specimen Label: 4A
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6313605
Age: embryonic day 14.5
Image: 4B
Note: Expression was detected in lymphatic endothelial cells.
Specimen Label: 4B
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6313605
Age: embryonic day 14.5
Image: 4C
Note: Expression was detected in lymphatic endothelial cells.
Specimen Label: 4C
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6313605
Age: embryonic day 14.5
Image: 4D
Note: Expression was detected in lymphatic endothelial cells.
Specimen Label: 4D
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6314707
Age: embryonic day 15.5
Note: Authors report disruption of proper formation of lymphatic network compared to that of control mice.
Specimen Label: 2D ICD/ICD Prox-1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6314707
Age: embryonic day 18.5
Note: Authors report no formation of collecting lymphatic vessels and valves in homozygous mutant mice.
Specimen Label: 3D ICD/ICD Prox-1
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6314707
Age: embryonic day 17.5
Note: Authors report disruption of remodeling of primary lymphatic network in homozygous mutant mice.
Specimen Label: 4B ICD/ICD Prox-1
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6314707
Age: embryonic day 18.5
Note: Authors report no formation of lymphatic valves in mesentery of homozygous mutants.
Specimen Label: 4C ICD/ICD Prox-1
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6314707
Age: embryonic day 18.5
Note: Authors report no formation of collecting lymphatic vessels and valves in homozygous mutant mice.
Specimen Label: 7G Ang2-/- Prox-1
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6314707
Age: postnatal
Specimen Label: 8A Prox-1
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6314707
Age: embryonic day 14.5
Specimen Label: S2 E14.5 ICD/ICD
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6314707
Age: embryonic day 14.5
Specimen Label: S2 E14.5 +/ICD
Detected: true
Specimen Num: 25
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•
GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6314707
Age: embryonic day 14.5
Specimen Label: S2 E14.5 +/+
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6314707
Age: embryonic day 15.5
Specimen Label: S2 E15.5 ICD/ICD
Detected: true
Specimen Num: 27
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6314707
Age: embryonic day 15.5
Note: Strong expression as valve morphogenesis is initiated with formation of lymphatic endothelial cell (LEC) clusters.
Specimen Label: S2 E15.5 +/ICD
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6314707
Age: embryonic day 15.5
Note: Strong expression as valve morphogenesis is initiated with formation of lymphatic endothelial cell (LEC) clusters.
Specimen Label: S2 E15.5 +/+
Detected: true
Specimen Num: 29
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6314707
Age: embryonic day 16.5
Specimen Label: S2 E16.5 ICD/ICD
Detected: true
Specimen Num: 30
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1824824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314707
Age: embryonic day 16.5
Note: Expression becomes more obvious in valve forming regions with condensed lymphatic endothelial cells.
Specimen Label: S2 E16.5 +/ICD
Detected: true
Specimen Num: 31
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1824824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6314707
Age: embryonic day 16.5
Note: Expression becomes more obvious in valve forming regions with condensed lymphatic endothelial cells.
Specimen Label: S2 E16.5 +/+
Detected: true
Specimen Num: 32
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6314707
Age: embryonic day 18.5
Note: Authors report remodeling of primary lymphatic network to form collecting vessels does not occur in homozygous mutant mice.
Specimen Label: S3A Ang2-/- Prox-1
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6314707
Age: embryonic day 18.5
Note: Authors report no formation of lymphatic valves in mesentery of homozygous mutant mice.
Specimen Label: S3B Ang2-/- Prox-1
Detected: true
Specimen Num: 36
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5587006
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6314707
Age: embryonic day 15.75
Note: Authors report disruption of proper formation of lymphatic network compared to that of control mice.
Specimen Label: 3C ICD/ICD Prox-1
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6364012
Age: embryonic day 10.5
Image: 3A
Note: Expression in lymphatic endothelial cells sprouting from cardinal vein.
Specimen Label: 3A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6364012
Age: embryonic day 10.5
Image: 3B
Note: Reduced number of expressing cells compared to wild type.
Specimen Label: 3B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6364012
Age: embryonic day 11.5
Image: 3C
Note: Expression in sprouting lymphatic endothelial cells.
Specimen Label: 3C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6364012
Age: embryonic day 11.5
Image: 3D
Note: Reduced sprouting of lymphatic endothelial cells.
Specimen Label: 3D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6364012
Age: embryonic day 10.5
Image: S2E/F
Note: Expression in lymphatic endothelial cells.
Specimen Label: S2E/F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6364012
Age: embryonic day 11.5
Image: S2H/I
Note: Expression in lymphatic endothelial cells.
Specimen Label: S2H/I
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6364012
Age: embryonic day 11.5
Image: S2K/L
Specimen Label: S2K/L
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5476685
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6364012
Age: embryonic day 10.5
Image: S2B/C
Note: Expression in lymphatic endothelial cells.
Specimen Label: S2B/C
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507013
Age: embryonic day 15.5
Image: S2B
Note: Expression in numerous lymphatic vessels. Authors report mostly normal-looking lymphatic vessels.
Specimen Label: S2B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1824821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6507015
Age: embryonic day 13.5
Image: 2H
Note: Few Prox1-expressing lymphatic vessels.
Specimen Label: 2H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6507015
Age: embryonic day 15.5
Image: 2J
Note: Few Prox1-expressing lymphatic vessels.
Specimen Label: 2J
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507015
Age: embryonic day 15.5
Image: 2I
Note: Authors report mostly normal-looking lymphatic vessels in skin.
Specimen Label: 2I
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507015
Age: embryonic day 15.5
Image: S2E
Specimen Label: S2E
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507015
Age: embryonic day 15.5
Image: S2F
Note: Authors report mostly normal-looking lymphatic vessels.
Specimen Label: S2F
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1824823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6507015
Age: embryonic day 15.5
Image: S2G
Note: Lymphatic vessels were abnormally shaped or reduced in size and thinner. Authors report complete lack of lymphatic vessels in some double-heterozygous embryos.
Specimen Label: S2G
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5E
Specimen Label: 5E
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5F
Specimen Label: 5F
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5E'
Specimen Label: 5E'
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5F'
Specimen Label: 5F'
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5G
Specimen Label: 5G
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5G'
Specimen Label: 5G'
Detected: true
Specimen Num: 25
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5H
Note: Expression significantly reduced compared with single heterozygous littermates
Specimen Label: 5H
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 5H'
Note: Expression significantly reduced compared with single heterozygous littermates
Specimen Label: 5H'
Detected: true
Specimen Num: 27
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6507015
Age: embryonic day 10.5
Image: S3A
Note: Expression in numerous lymphatic endothelial cells (LECs) lining the anterior cardinal vein and budding from the vein.
Specimen Label: S3A
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1824817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6507015
Age: embryonic day 10.5
Image: S3B
Note: Severely reduced number of expressing cells inside the cardinal vein; almost none outside the vein.
Specimen Label: S3B
Detected: true
Specimen Num: 29
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 30
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 7B
Note: Expression in fewer lymphatic endothelial cell (LEC) progenitors and LECs compared with wild-type.
Specimen Label: 7B
Detected: true
Specimen Num: 31
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 7C
Note: Expression in fewer lymphatic endothelial cell (LEC) progenitors and LECs compared with wild-type.
Specimen Label: 7C
Detected: true
Specimen Num: 32
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: 7D
Note: Expression in even fewer lymphatic endothelial cell (LEC) progenitors and LECs compared with single heterozygous littermates.
Specimen Label: 7D
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: S4A/C
Specimen Label: S4A/C
Detected: true
Specimen Num: 34
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5486156
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6507015
Age: embryonic day 11.5
Image: S4D/F
Specimen Label: S4D/F
Detected: true
Specimen Num: 35
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5587807
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6758976
Age: embryonic day 13.5
Image: 2D/E
Note: Colocalized with Isl1+ lineage around the aorta.
Specimen Label: 2D/E
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6758996
Age: embryonic day 12.5
Image: 5E/F
Note: Mesh-like networks composed of Prox1+ and/or Flt4+ cells appeared, surrounding the outflow tract.
Specimen Label: 5E/F
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6781831
Assay Type: Immunohistochemistry
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6781839
Age: embryonic day 11.5
Image: 1O
Note: Expressed in lymphatic endothelial cells.
Specimen Label: 1O
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-16
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7539743
Age: embryonic day 14.5
Note: Expression is in the endothelial cells of thoracic duct.
Specimen Label: 2e
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7539743
Age: postnatal day 7
Note: Expression is in the jugular lymph sac and small lymphatics.
Specimen Label: 6b
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7539743
Age: embryonic day 11.5
Note: Expression is in sprouting lymphatic endothelial cells.
Specimen Label: 1b
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-16
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7539743
Age: embryonic day 14.5
Note: Expression is in the endothelial cells of thoracic duct.
Specimen Label: 2f
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5555854
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7539743
Age: postnatal day 7
Note: Expression is in the jugular lymph sac and small lymphatics.
Specimen Label: 6c
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5551742
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:7595504
Age: embryonic day 11.0
Note: Expression in lymphatic endothelial cells.
Specimen Label: 7A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5551742
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:7595504
Age: embryonic day 11.0
Note: No difference in formation of first lymphatic structures between wild-type and mutant.
Specimen Label: 7B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5551742
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7595504
Age: embryonic day 12.5
Note: Expression in lymphatic endothelial cells.
Specimen Label: 7C
Detected: true
Specimen Num: 3
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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