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Search results 1001 to 1099 out of 1099 for Smo

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Type Details Score
Publication
First Author: Sun J
Year: 2021
Journal: Nat Commun
Title: SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts.
Volume: 12
Issue: 1
Pages: 4611
Publication
First Author: Khan M
Year: 2007
Journal: Gene Expr Patterns
Title: Hedgehog pathway gene expression during early development of the molar tooth root in the mouse.
Volume: 7
Issue: 3
Pages: 239-43
Publication
First Author: Tukachinsky H
Year: 2010
Journal: J Cell Biol
Title: A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.
Volume: 191
Issue: 2
Pages: 415-28
Publication
First Author: Teperino R
Year: 2012
Journal: Cell
Title: Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.
Volume: 151
Issue: 2
Pages: 414-26
Publication
First Author: Jiang K
Year: 2016
Journal: PLoS Biol
Title: PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail.
Volume: 14
Issue: 2
Pages: e1002375
Publication  
First Author: Hyun J
Year: 2016
Journal: Nat Commun
Title: MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.
Volume: 7
Pages: 10993
Publication  
First Author: Schou KB
Year: 2017
Journal: Nat Commun
Title: KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
Volume: 8
Pages: 14177
Publication
First Author: Shi X
Year: 2017
Journal: Nat Cell Biol
Title: Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome.
Volume: 19
Issue: 10
Pages: 1178-1188
Publication  
First Author: Li XY
Year: 2018
Journal: Cancer Lett
Title: Cynanbungeigenin C and D, a pair of novel epimers from Cynanchum bungei, suppress hedgehog pathway-dependent medulloblastoma by blocking signaling at the level of Gli.
Volume: 420
Pages: 195-207
Publication
First Author: Lu W
Year: 2018
Journal: Blood
Title: Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis.
Volume: 131
Issue: 3
Pages: 323-327
Publication
First Author: Chahal KK
Year: 2019
Journal: PLoS One
Title: Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.
Volume: 14
Issue: 9
Pages: e0214901
Publication  
First Author: Kothandapani A
Year: 2021
Journal: Mol Cell Endocrinol
Title: Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium.
Volume: 531
Pages: 111265
Publication
First Author: Shao F
Year: 2021
Journal: Nat Commun
Title: Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis.
Volume: 12
Issue: 1
Pages: 6540
Publication  
First Author: Lv B
Year: 2022
Journal: J Cell Sci
Title: Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation.
Volume: 135
Issue: 16
Publication
First Author: Dey J
Year: 2013
Journal: Cancer Res
Title: MyoD is a tumor suppressor gene in medulloblastoma.
Volume: 73
Issue: 22
Pages: 6828-37
Publication    
First Author: Bassett EA
Year: 2016
Journal: Elife
Title: Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.
Volume: 5
Publication
First Author: Colvin Wanshura LE
Year: 2011
Journal: Cancer Res
Title: Sequential activation of Snail1 and N-Myc modulates sonic hedgehog-induced transformation of neural cells.
Volume: 71
Issue: 15
Pages: 5336-45
Publication
First Author: Pokrajac NT
Year: 2023
Journal: Dev Cell
Title: Meningeal macrophages inhibit chemokine signaling in pre-tumor cells to suppress mouse medulloblastoma initiation.
Volume: 58
Issue: 20
Pages: 2015-2031.e8
Publication
First Author: Sengupta R
Year: 2012
Journal: Cancer Res
Title: CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma.
Volume: 72
Issue: 1
Pages: 122-32
Publication
First Author: Sankar S
Year: 2017
Journal: Genes Cancer
Title: Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors.
Volume: 8
Issue: 9-10
Pages: 725-744
Publication
First Author: Milla LA
Year: 2014
Journal: Int J Cancer
Title: Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
Volume: 134
Issue: 1
Pages: 21-31
Publication
First Author: Lindsey JC
Year: 2015
Journal: Oncogene
Title: Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance.
Volume: 34
Issue: 36
Pages: 4746-57
Publication
First Author: Gershon TR
Year: 2013
Journal: Cancer Metab
Title: Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma.
Volume: 1
Issue: 1
Pages: 2
Publication
First Author: Bay SN
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
Volume: 115
Issue: 7
Pages: 1570-1575
Publication
First Author: Pallavicini G
Year: 2018
Journal: Cancer Res
Title: Inactivation of Citron Kinase Inhibits Medulloblastoma Progression by Inducing Apoptosis and Cell Senescence.
Volume: 78
Issue: 16
Pages: 4599-4612
Publication
First Author: Wu C
Year: 2017
Journal: Hum Mol Genet
Title: Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.
Volume: 26
Issue: 13
Pages: 2386-2397
Publication
First Author: Ruiz-Perez VL
Year: 2007
Journal: Development
Title: Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia.
Volume: 134
Issue: 16
Pages: 2903-12
Publication
First Author: Park JY
Year: 2016
Journal: Development
Title: The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state.
Volume: 143
Issue: 1
Pages: 133-46
Publication
First Author: Cervelli M
Year: 2004
Journal: Eur J Biochem
Title: Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoform.
Volume: 271
Issue: 4
Pages: 760-70
Publication
First Author: Cooper AF
Year: 2005
Journal: Development
Title: Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.
Volume: 132
Issue: 19
Pages: 4407-17
Publication
First Author: Yang N
Year: 2015
Journal: Development
Title: Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.
Volume: 142
Issue: 12
Pages: 2194-202
Publication
First Author: Yang N
Year: 2017
Journal: Oncogene
Title: INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.
Volume: 36
Issue: 35
Pages: 4997-5005
Publication
First Author: Goodwin AC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Volume: 108
Issue: 37
Pages: 15354-9
Publication
First Author: Chang H
Year: 2012
Journal: Dev Biol
Title: Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.
Volume: 370
Issue: 2
Pages: 187-97
Publication
First Author: Okolowsky N
Year: 2014
Journal: Dev Biol
Title: Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.
Volume: 391
Issue: 2
Pages: 219-29
Publication
First Author: Yang F
Year: 2022
Journal: Mol Cancer Res
Title: A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth.
Volume: 20
Issue: 11
Pages: 1598-1610
Publication
First Author: Dijkgraaf GJ
Year: 2011
Journal: Cancer Res
Title: Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.
Volume: 71
Issue: 2
Pages: 435-44
Publication
First Author: Li B
Year: 2014
Journal: Cancer Res
Title: Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Volume: 74
Issue: 17
Pages: 4811-21
Publication
First Author: Moraes RC
Year: 2007
Journal: Development
Title: Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
Volume: 134
Issue: 6
Pages: 1231-42
Publication
First Author: Rajurkar M
Year: 2014
Journal: Oncogene
Title: Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.
Volume: 33
Issue: 46
Pages: 5370-8
Publication
First Author: Atwood SX
Year: 2013
Journal: Nature
Title: GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Volume: 494
Issue: 7438
Pages: 484-8
Publication
First Author: Szczepny A
Year: 2017
Journal: Oncogene
Title: The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer.
Volume: 36
Issue: 39
Pages: 5544-5550
Publication
First Author: Tang Y
Year: 2014
Journal: Nat Med
Title: Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
Volume: 20
Issue: 7
Pages: 732-40
Publication
First Author: Fan Q
Year: 2010
Journal: J Biol Chem
Title: Requirement of TGFbeta signaling for SMO-mediated carcinogenesis.
Volume: 285
Issue: 47
Pages: 36570-6
Publication
First Author: Blassberg R
Year: 2016
Journal: Hum Mol Genet
Title: Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.
Volume: 25
Issue: 4
Pages: 693-705
Publication
First Author: Kugler MC
Year: 2019
Journal: Exp Lung Res
Title: The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis.
Volume: 45
Issue: 1-2
Pages: 22-29
Publication
First Author: Lee MJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Volume: 109
Issue: 20
Pages: 7859-64
Publication
First Author: Tan IL
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
Volume: 115
Issue: 13
Pages: 3392-3397
Publication
First Author: Wang X
Year: 2017
Journal: Biol Reprod
Title: Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg.
Volume: 97
Issue: 6
Pages: 822-834
Publication
First Author: Zahedi K
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.
Volume: 299
Issue: 1
Pages: C164-74
Publication
First Author: Tateya T
Year: 2013
Journal: Development
Title: Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea.
Volume: 140
Issue: 18
Pages: 3848-57
Publication  
First Author: Revenkova E
Year: 2018
Journal: J Cell Sci
Title: The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane.
Volume: 131
Issue: 9
Publication
First Author: Lee J
Year: 2023
Journal: Sci Rep
Title: Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.
Volume: 13
Issue: 1
Pages: 12309
Publication  
First Author: Fish EW
Year: 2024
Journal: Reprod Toxicol
Title: Efcab7 deletion sensitizes mice to the teratogenic effects of gastrulation-stage alcohol exposure.
Volume: 130
Pages: 108729
Publication
First Author: Yang S
Year: 2012
Journal: Bone
Title: The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis.
Volume: 51
Issue: 3
Pages: 407-17
Publication
First Author: Carpenter D
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Characterization of two patched receptors for the vertebrate hedgehog protein family.
Volume: 95
Issue: 23
Pages: 13630-4
Publication
First Author: Grachtchouk V
Year: 2003
Journal: EMBO J
Title: The magnitude of hedgehog signaling activity defines skin tumor phenotype.
Volume: 22
Issue: 11
Pages: 2741-51
Publication
First Author: Athar M
Year: 2004
Journal: Cancer Res
Title: Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.
Volume: 64
Issue: 20
Pages: 7545-52
Publication
First Author: Kim Y
Year: 2007
Journal: Cancer Res
Title: Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
Volume: 67
Issue: 8
Pages: 3583-93
Publication
First Author: Wu J
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Neuroprotective effect of upregulated sonic Hedgehog in retinal ganglion cells following chronic ocular hypertension.
Volume: 51
Issue: 6
Pages: 2986-92
Publication
First Author: Mar BG
Year: 2011
Journal: Leukemia
Title: The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.
Volume: 25
Issue: 11
Pages: 1665-73
Publication
First Author: Meng Q
Year: 2014
Journal: PLoS One
Title: Expression of signaling components in embryonic eyelid epithelium.
Volume: 9
Issue: 2
Pages: e87038
Publication
First Author: Carbe CJ
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Gi proteins mediate activation of the canonical hedgehog pathway in the myocardium.
Volume: 307
Issue: 1
Pages: H66-72
Publication
First Author: Athar M
Year: 2014
Journal: Cancer Res
Title: Sonic hedgehog signaling in Basal cell nevus syndrome.
Volume: 74
Issue: 18
Pages: 4967-75
Publication
First Author: Kharebava G
Year: 2015
Journal: Biol Open
Title: N-docosahexaenoylethanolamine regulates Hedgehog signaling and promotes growth of cortical axons.
Volume: 4
Issue: 12
Pages: 1660-70
Publication
First Author: Kwon IK
Year: 2015
Journal: Biochim Biophys Acta
Title: Mitochondrial function contributes to oxysterol-induced osteogenic differentiation in mouse embryonic stem cells.
Volume: 1853
Issue: 3
Pages: 561-72
Publication
First Author: Cheng L
Year: 2018
Journal: J Biol Chem
Title: Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes and prolongs cardiac action potential duration.
Volume: 293
Issue: 28
Pages: 11022-11032
Publication  
First Author: Woods S
Year: 2019
Journal: Matrix Biol
Title: miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse.
Volume: 77
Pages: 87-100
Publication  
First Author: Coni S
Year: 2017
Journal: Sci Rep
Title: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Volume: 7
Pages: 44079
Publication  
First Author: Pusapati GV
Year: 2018
Journal: Sci Signal
Title: G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Volume: 11
Issue: 516
Publication
First Author: Zhang L
Year: 2022
Journal: J Bone Miner Res
Title: Hedgehog Signaling Controls Bone Homeostasis by Regulating Osteogenic/Adipogenic Fate of Skeletal Stem/Progenitor Cells in Mice.
Volume: 37
Issue: 3
Pages: 559-576
Publication
First Author: Saeki N
Year: 2022
Journal: Exp Cell Res
Title: Pregnane X receptor (PXR) represses osteoblast differentiation through repression of the Hedgehog signaling pathway.
Volume: 416
Issue: 1
Pages: 113156
Publication  
First Author: Xiu C
Year: 2022
Journal: Front Cell Dev Biol
Title: Suppressor of fused-restrained Hedgehog signaling in chondrocytes is critical for epiphyseal growth plate maintenance and limb elongation in juvenile mice.
Volume: 10
Pages: 997838
Publication
First Author: Morimoto Y
Year: 2022
Journal: Neurochem Res
Title: TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and Brain Tumor Initiating Cells Regulated by Macrophage Migration Inhibitory Factor (MIF).
Volume: 47
Issue: 9
Pages: 2741-2756
Publication  
First Author: Xu J
Year: 2022
Journal: Development
Title: The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis.
Volume: 149
Issue: 21
Publication
First Author: Tsiami F
Year: 2024
Journal: Acta Neuropathol Commun
Title: Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma.
Volume: 12
Issue: 1
Pages: 125
Publication
First Author: Yoshida S
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.
Volume: 121
Issue: 28
Pages: e2320070121
Publication
First Author: Crowther AJ
Year: 2013
Journal: J Neurosci
Title: Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma.
Volume: 33
Issue: 46
Pages: 18098-108
Publication  
First Author: Blair HJ
Year: 2011
Journal: BMC Biol
Title: Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus.
Volume: 9
Pages: 14
Publication
First Author: Paudel S
Year: 2022
Journal: Carcinogenesis
Title: Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
Volume: 43
Issue: 6
Pages: 557-570
Publication
First Author: Braune J
Year: 2017
Journal: Diabetologia
Title: Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism.
Volume: 60
Issue: 5
Pages: 889-899
Publication
First Author: Kimi K
Year: 2003
Journal: J Oral Pathol Med
Title: Immunohistochemical and genetic analysis of mandibular cysts in heterozygous ptc knockout mice.
Volume: 32
Issue: 2
Pages: 108-13
Publication
First Author: Cervelli M
Year: 2013
Journal: PLoS One
Title: A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury.
Volume: 8
Issue: 6
Pages: e64810
Publication  
First Author: Franco A
Year: 2018
Journal: J Mol Cell Cardiol
Title: G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.
Volume: 121
Pages: 60-68
Publication  
First Author: Liu X
Year: 2017
Journal: Bone
Title: Exogenous hedgehog antagonist delays but does not prevent fracture healing in young mice.
Volume: 103
Pages: 241-251
Publication
First Author: Chapouly C
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Volume: 40
Issue: 12
Pages: e336-e349
Publication
First Author: Vujcic S
Year: 2003
Journal: Biochem J
Title: Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion.
Volume: 370
Issue: Pt 1
Pages: 19-28
Publication
First Author: Hor CHH
Year: 2021
Journal: J Neurosci
Title: Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
Volume: 41
Issue: 32
Pages: 6850-6863
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Williams SE
Year: 2015
Journal: Development
Title: Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.
Volume: 142
Issue: 22
Pages: 3921-32
Publication
First Author: Diede SJ
Year: 2013
Journal: Epigenetics
Title: Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer.
Volume: 8
Issue: 12
Pages: 1254-60
Protein
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhou X
Year: 2016
Journal: Exp Neurol
Title: Effect of the sonic hedgehog receptor smoothened on the survival and function of dopaminergic neurons.
Volume: 283
Issue: Pt A
Pages: 235-45
Publication
First Author: Niu C
Year: 2019
Journal: Autophagy
Title: Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.
Volume: 15
Issue: 5
Pages: 843-870
Publication
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7