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Search results 1001 to 1091 out of 1091 for Sox17

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Type Details Score
HT Experiment
GSE190043 | Single-cell RNA sequencing on the testis from the rete testis-specific Sox17 conditional knockout (cKO) mice and the controls at P14.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Interaction Experiment
Li W (2019)
Description: TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.
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Publication
- | J:349708
     
First Author: Magnuson MA
Year: 2024
Journal: MGI Direct Data Submission
Title: Direct Data Submission Alleles.
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Regulatory Region
MGI:7339163 | Rr271
Type: intronic_regulatory_region
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7543618
Assay Type: RNA in situ
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7543630
Age: embryonic day 9.75
Image: 4H
Note: Expressed not only in the ventral pancreatic bud, but also in the region where Sox17 was intrinsically expressed (presumptive gall bladder region).
Specimen Label: 4H
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:7541030
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541116
Age: embryonic day 5.0
Image: S3c -/-
Note: Positive cells did not exhibit epithelial structure but they appeared as a clump (accumulated Sox17 too), and exhibited defects in apical-basolateral polarity.
Specimen Label: S3c -/-
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
Probe: MGI:7541030
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7541116
Age: embryonic day 5.5
Image: S3d -/-
Note: Positive cells did not exhibit epithelial structure but they appeared as a clump (accumulated Sox17 too), and exhibited defects in apical-basolateral polarity.
Specimen Label: S3d -/-
Detected: true
Specimen Num: 26
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HT Experiment
GSE74576 | Expression data from gall bladder and cystic duct in wild type and Sox17+/-mice at 15 dpc
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Allele
Rr271<em2Mgn> | MGI:7461678
Name: regulatory region 271; endonuclease-mediated mutation 2, Mark A Magnuson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:7840366 | STOCK Rr271<em2Mgn>/Vu
Attribute String: endonuclease-mediated mutation, mutant stock
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Strain
MGI:8158720 | STOCK Rr271<em2Mgn>/Mng
Attribute String: endonuclease-mediated mutation, mutant stock
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Allele
Rr460<em1Mgn> | MGI:7530991
Name: regulatory region 460; endonuclease-mediated mutation 1, Mark A Magnuson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr446<em1Mgn> | MGI:7522923
Name: regulatory region 446; endonuclease-mediated mutation 1, Mark A Magnuson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Rr271/Rr271
Background: STOCK Rr271/Mng
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE125321 | Single cell expression profiling of the mouse Sox17-null endocardium at E8.5
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE125322 | Single cell expression profiling of the mouse Sox17-null myocardium at E8.5
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Publication
10549281 | -
First Author: Zorn AM
Year: 1999
Journal: Mol Cell
Title: Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin.
Volume: 4
Issue: 4
Pages: 487-98
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Protein Domain
IPR033392 | Sox7/17/18_central
Type: Domain
Description: This is the central region of eukaryotic SOX17 and 18 transcription factor proteins []. It lies just downstream of the HMG-box domain, and is followed by a C-terminal domain.
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HT Experiment
E-MTAB-12719 | Single-cell transcriptomic analysis of Sox17-expressing lineages reveals dynamic developmental trajectories and distinct gene regulatory networks during embryogenesis
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Allele
Sox17<tm1Smoc> | MGI:7292541
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:7840371 | STOCK Rr446<em1Mgn>/Vu
Attribute String: endonuclease-mediated mutation, mutant stock
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Allele
Sox17<tm1.1Itl> | MGI:7855939
Name: SRY (sex determining region Y)-box 17; targeted mutation 1.1, InGenious Targeting Laboraory
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Sox17<tm1Sjm> | MGI:3717118
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Sean J Morrison
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Sox17<tm2Sjm> | MGI:3717121
Name: SRY (sex determining region Y)-box 17; targeted mutation 2, Sean J Morrison
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Rr270<em1Mgn> | MGI:7339168
Name: regulatory region 270; endonuclease-mediated mutation 1, Mark A Magnuson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:6476353 | C57BL/6JSmoc-Sox17<tm1Smoc>/Smoc
Attribute String: coisogenic, targeted mutation, mutant strain
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Strain
MGI:3718106 | BKa.129-Sox17<tm1Sjm>
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Sox17<tm1(icre)Heli> | MGI:3852645
Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Heiko Lickert
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Sox17<tm2.1(icre)Heli> | MGI:4418897
Name: SRY (sex determining region Y)-box 17; targeted mutation 2.1, Heiko Lickert
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:7840305 | STOCK Rr270<em1Mgn>/Vu
Attribute String: endonuclease-mediated mutation, mutant stock
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: BKa.129-Sox17
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr270/Rr270
Background: involves: CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr271/Rr271<+> Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * CD-1
Zygosity: cx
Has Mutant Allele: true
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HT Experiment
E-GEOD-33353 | Total expression profiling of embryonic regions of EHF mouse embryos
Series Id: GSE33353
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Strain
MGI:3718204 | BKa.Cg-Sox17<tm2Sjm> Ptprc<b> Thy1<a>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Sox17<tm4.1(icre/ERT2)Heli> | MGI:5543602
Name: SRY (sex determining region Y)-box 17; targeted mutation 4.1, Heiko Lickert
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Cdh5-cre/ERT2)1Rha/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17<+> Tbx1/Tbx1
Background: involves: 129S6/SvEvTac * 129/Sv * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S2/SvPas * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mesp1/Mesp1<+> Sox17/Sox17
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Nfat1c-cre)1Bz/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
28235195 | J:239668
First Author: Cheng CW
Year: 2017
Journal: Cell
Title: Fasting-Mimicking Diet Promotes Ngn3-Driven ?-Cell Regeneration to Reverse Diabetes.
Volume: 168
Issue: 5
Pages: 775-788.e12
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Publication
15645446 | J:95910
First Author: Perl AK
Year: 2005
Journal: Genesis
Title: Normal lung development and function after Sox9 inactivation in the respiratory epithelium.
Volume: 41
Issue: 1
Pages: 23-32
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Publication
36341977 | J:331481
 
First Author: Liu Y
Year: 2022
Journal: Gene Expr Patterns
Title: Expression patterns and biological function of BCL2L10 during mouse preimplantation development.
Volume: 46
Pages: 119285
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Publication
19736317 | J:382073
First Author: Stefanovic S
Year: 2009
Journal: J Cell Biol
Title: Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate.
Volume: 186
Issue: 5
Pages: 665-73
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Strain
MGI:3717926 | BKa.Cg-Sox17<tm1Sjm> Ptprc<b> Thy1<a>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Mx1-cre)1Cgn/?
Background: involves: 129/Sv * C3H * C57BL/6 * C57BL/Ka * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Foxa3-cre)1Khk/?
Background: involves: 129 * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nipbl/Nipbl<+> Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Shh/Shh<+> Sox17/Sox17
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf3/Fgf3<+> Fgf8/Fgf8<+> Sox17/Sox17<+>
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/Fgfr1 Fgfr2/Fgfr2 Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
15829580 | J:293047
First Author: Horowitz E
Year: 2005
Journal: Mol Hum Reprod
Title: Patterns of expression of sperm flagellar genes: early expression of genes encoding axonemal proteins during the spermatogenic cycle and shared features of promoters of genes encoding central apparatus proteins.
Volume: 11
Issue: 4
Pages: 307-17
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Publication
41790751 | J:381086
First Author: Lilao-Garz?n J
Year: 2026
Journal: PLoS One
Title: Wnt/?-catenin signalling modulates the timing of cell fate decision making in the early mouse embryo.
Volume: 21
Issue: 3
Pages: e0344295
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Publication
37394586 | J:338876
First Author: Lee JW
Year: 2023
Journal: Exp Mol Med
Title: SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction.
Volume: 55
Issue: 7
Pages: 1424-1436
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Publication
25908864 | J:232658
First Author: Taylor-Weiner H
Year: 2015
Journal: J Cell Sci
Title: Traction forces mediated by integrin signaling are necessary for definitive endoderm specification.
Volume: 128
Issue: 10
Pages: 1961-8
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Publication
25897113 | J:232661
First Author: Chatagnon A
Year: 2015
Journal: Nucleic Acids Res
Title: RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.
Volume: 43
Issue: 10
Pages: 4833-54
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Publication
33899080 | J:308783
First Author: Shi Y
Year: 2021
Journal: Biol Reprod
Title: Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos?.
Volume: 105
Issue: 2
Pages: 359-370
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Tek-cre)12Flv/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * C57BL/Ka
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf3/Fgf3 Fgf8/Fgf8<+> Sox17/Sox17<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf3/Fgf3<+> Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf3/Fgf3 Fgf8/Fgf8 Sox17/Sox17<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Sox17/Sox17
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Sox17/Sox17
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Setdb1/Setdb1<+> Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Setdb1/Setdb1 Sox17/Sox17<+> Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Publication
- | J:367121
       
First Author: Vanderbilt
Year: 2025
Title: Direct Data Submissions from Vanderbilt Cryopreserved Mouse Repository (VCMR).
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Protein
P40646
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
P43680
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
Q61473
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
Q3U1W5
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
A0A0A6YXS3
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
Q3U0W9
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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