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Search results 1001 to 1100 out of 1344 for T2

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Hits by Pathway

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_15
Specimen Label: euxassay_010397_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_16
Specimen Label: euxassay_010397_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_17
Specimen Label: euxassay_010397_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_18
Specimen Label: euxassay_010397_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_19
Specimen Label: euxassay_010397_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_20
Specimen Label: euxassay_010397_20
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_21
Specimen Label: euxassay_010397_21
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
 
Probe: MGI:4417506
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4822645
Age: embryonic day 14.5
Image: euxassay_010397_22
Specimen Label: euxassay_010397_22
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:5000568
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541128
Age: embryonic day 15.5
Image: GUDMAP:5042
Specimen Label: GUDMAP:5042
Detected: true
Specimen Num: 1
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Protein
Q61153
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Protein
Q91ZI8
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
A0A0R4J110
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Protein
Q9Z1Y9
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Publication
22343712 | J:212665
First Author: Huang ZP
Year: 2012
Journal: Circ Res
Title: CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy.
Volume: 110
Issue: 6
Pages: 818-30
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Publication
20538684 | J:175042
First Author: Cheng H
Year: 2010
Journal: Circ Res
Title: Loss of enigma homolog protein results in dilated cardiomyopathy.
Volume: 107
Issue: 3
Pages: 348-56
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Publication
28566470 | J:252677
First Author: Barrios J
Year: 2017
Journal: FASEB J
Title: Early life allergen-induced mucus overproduction requires augmented neural stimulation of pulmonary neuroendocrine cell secretion.
Volume: 31
Issue: 9
Pages: 4117-4128
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Publication
22158708 | J:192707
First Author: He A
Year: 2012
Journal: Circ Res
Title: Polycomb repressive complex 2 regulates normal development of the mouse heart.
Volume: 110
Issue: 3
Pages: 406-15
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Publication
24763434 | J:215161
First Author: Hardiman KM
Year: 2014
Journal: PLoS One
Title: Rapamycin inhibition of polyposis and progression to dysplasia in a mouse model.
Volume: 9
Issue: 4
Pages: e96023
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Publication
19652092 | J:167114
First Author: Liang X
Year: 2009
Journal: Circulation
Title: Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.
Volume: 120
Issue: 7
Pages: 568-76
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Publication
38619323 | J:347802
 
First Author: Shi W
Year: 2024
Journal: Development
Title: CHD4 and SMYD1 repress common transcriptional programs in the developing heart.
Volume: 151
Issue: 8
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Publication
33665549 | J:306925
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
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Publication
25249570 | J:252769
First Author: Lin Z
Year: 2015
Journal: Circ Res
Title: Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival.
Volume: 116
Issue: 1
Pages: 35-45
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Publication
20037164 | J:160029
First Author: Maillet M
Year: 2010
Journal: J Biol Chem
Title: Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.
Volume: 285
Issue: 9
Pages: 6716-24
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Publication
36745292 | J:335098
First Author: Han F
Year: 2023
Journal: Angiogenesis
Title: Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription.
Volume: 26
Issue: 2
Pages: 217-232
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Publication
29891551 | J:267108
First Author: Cho E
Year: 2018
Journal: J Biol Chem
Title: Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.
Volume: 293
Issue: 30
Pages: 11659-11673
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Publication
29891665 | J:263962
First Author: Wilczewski CM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: CHD4 and the NuRD complex directly control cardiac sarcomere formation.
Volume: 115
Issue: 26
Pages: 6727-6732
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Publication
30982350 | J:290931
First Author: Liu C
Year: 2019
Journal: Circulation
Title: Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation.
Volume: 140
Issue: 1
Pages: 55-66
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Publication
38994028 | J:351071
First Author: Chen T
Year: 2024
Journal: Theranostics
Title: Transfer of cardiomyocyte-derived extracellular vesicles to neighboring cardiac cells requires tunneling nanotubes during heart development.
Volume: 14
Issue: 10
Pages: 3843-3858
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Publication
27956497 | J:247285
First Author: Zhang D
Year: 2017
Journal: Nucleic Acids Res
Title: Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Volume: 45
Issue: 6
Pages: 3102-3115
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Publication
36740741 | J:349501
First Author: Ohman LC
Year: 2023
Journal: J Comp Neurol
Title: Taste arbor structural variability analyzed across taste regions.
Volume: 531
Issue: 7
Pages: 743-758
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Publication
37852970 | J:341678
First Author: Kemmler CL
Year: 2023
Journal: Nat Commun
Title: Conserved enhancers control notochord expression of vertebrate Brachyury.
Volume: 14
Issue: 1
Pages: 6594
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Genotype
Genotype
Symbol: Bmp4/Bmp4 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S/Sv * Black Swiss * C57BL/6 * DBA/2 * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smo/Smo Tg(Tnnt2-cre)5Blh/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tarbp2/Tarbp2 Tg(tetO-Mir208a)#Dzw/? Tg(Tnnt2-cre)5Blh/?
Background: involves: 129 * C3H * C57BL/6 * DBA/2J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mib1/Mib1 Tg(Tnnt2-cre)5Blh/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tnnt2-cre)5Blh/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ntrk2/Ntrk2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bdnf/Bdnf<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ntrk2/Ntrk2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tacr1/Tacr1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Protein
Q64191
Organism: Mus musculus/domesticus
Length: 346  
Fragment?: false
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Protein
B7ZNK6
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
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Protein
A2RSS6
Organism: Mus musculus/domesticus
Length: 346  
Fragment?: false
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Publication
17681535 | -
First Author: Graham SC
Year: 2007
Journal: J Mol Biol
Title: Structure of CrmE, a virus-encoded tumour necrosis factor receptor.
Volume: 372
Issue: 3
Pages: 660-71
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Publication
8091665 | -
First Author: Hu FQ
Year: 1994
Journal: Virology
Title: Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
Volume: 204
Issue: 1
Pages: 343-56
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Publication
11022793 | -
First Author: Xu X
Year: 2000
Journal: Virus Genes
Title: Myxoma virus expresses a TNF receptor homolog with two distinct functions.
Volume: 21
Issue: 1-2
Pages: 97-109
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Protein Domain
IPR034059 | TNFRSF_N_viral
Type: Domain
Description: Viral TNFR homologues include vaccinia virus (VACV) cytokine response modifier E (CrmE) [], an encoded TNFR that shares significant sequence similarity with mammalian type 2 TNF receptors (TNFSFR1B, p75, TNFR type 2) [], a cowpox virus encoded cytokine-response modifier B (CrmB) [], which is a secreted form of TNF receptor that can contribute to the modification of TNF-mediated antiviral processes, and a myxoma virus (MYXV) T2 (M-T2) protein that binds and inhibits rabbit TNF-alpha []. The CrmE structure confirms that the canonical TNFR fold is adopted, but only one of the two "ligand-binding"loops of TNFRSF1A is conserved, suggesting a mechanism for the higher affinity of poxvirusTNFRs for TNFalpha over lymphotoxin-alpha []. CrmB protein specifically binds TNF-alpha and TNF-beta indicating that cowpox virus seeks to invade antiviral processes mediated by TNF. Intracellular M-T2 blocks virus-induced lymphocyte apoptosis via a highly conserved viral preligand assembly domain (vPLAD), which controls receptor signaling competency prior to ligand binding [].This entry represents the N-terminal domain of viral TNFRs. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Publication
17725607 | J:134805
First Author: Hasan M
Year: 2008
Journal: Immunology
Title: Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.
Volume: 123
Issue: 2
Pages: 239-49
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Publication
3092218 | J:8410
First Author: Sullivan KA
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.
Volume: 83
Issue: 18
Pages: 6687-91
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Publication
3181157 | J:14722
First Author: Deutzmann R
Year: 1988
Journal: Eur J Biochem
Title: Structural study of long arm fragments of laminin. Evidence for repetitive C-terminal sequences in the A-chain, not present in the B-chains.
Volume: 177
Issue: 1
Pages: 35-45
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Publication
11971015 | J:112154
First Author: Traynor TR
Year: 2002
Journal: J Immunol
Title: Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity.
Volume: 168
Issue: 9
Pages: 4659-66
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Publication
28378771 | J:274160
 
First Author: Tanwar S
Year: 2017
Journal: Sci Rep
Title: Mediation of transitional B cell maturation in the absence of functional Bruton's tyrosine kinase.
Volume: 7
Pages: 46029
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Publication
18223169 | J:133536
First Author: Rodríguez-Alba JC
Year: 2008
Journal: Blood
Title: CD38 induces differentiation of immature transitional 2 B lymphocytes in the spleen.
Volume: 111
Issue: 7
Pages: 3644-52
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Publication
28826559 | J:243985
First Author: Vohra R
Year: 2017
Journal: Am J Pathol
Title: Magnetic Resonance Monitoring of Disease Progression in mdx Mice on Different Genetic Backgrounds.
Volume: 187
Issue: 9
Pages: 2060-2070
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Publication
19265127 | J:145926
First Author: Blair PA
Year: 2009
Journal: J Immunol
Title: Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice.
Volume: 182
Issue: 6
Pages: 3492-3502
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Publication
25392270 | J:218206
First Author: Lee YH
Year: 2015
Journal: FASEB J
Title: Cellular origins of cold-induced brown adipocytes in adult mice.
Volume: 29
Issue: 1
Pages: 286-99
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Publication
31757993 | J:287316
First Author: Schaftenaar FH
Year: 2019
Journal: Sci Rep
Title: Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model.
Volume: 9
Issue: 1
Pages: 17391
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Publication
21605113 | J:175948
First Author: Coppieters KT
Year: 2011
Journal: Clin Exp Immunol
Title: Incidental CD8 T cell reactivity against caspase-cleaved apoptotic self-antigens from ubiquitously expressed proteins in islets from prediabetic human leucocyte antigen-A2 transgenic non-obese diabetic mice.
Volume: 165
Issue: 2
Pages: 155-62
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Publication
19494297 | J:149292
First Author: Castro I
Year: 2009
Journal: J Immunol
Title: B cell receptor-mediated sustained c-Rel activation facilitates late transitional B cell survival through control of B cell activating factor receptor and NF-kappaB2.
Volume: 182
Issue: 12
Pages: 7729-37
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Publication
19843948 | J:156793
First Author: Hoek KL
Year: 2009
Journal: J Immunol
Title: Absence of mature peripheral B cell populations in mice with concomitant defects in B cell receptor and BAFF-R signaling.
Volume: 183
Issue: 9
Pages: 5630-43
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Publication
12753808 | J:119452
First Author: Nakamura A
Year: 2003
Journal: J Autoimmun
Title: Deregulation of peripheral B-cell development in enhanced severity of collagen-induced arthritis in FcgammaRIIB-deficient mice.
Volume: 20
Issue: 3
Pages: 227-36
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Publication
15876460 | J:104445
First Author: Van Dam D
Year: 2005
Journal: Behav Brain Res
Title: Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS).
Volume: 162
Issue: 2
Pages: 233-9
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Publication
1881263 | J:27285
First Author: Towner RA
Year: 1991
Journal: Magn Reson Imaging
Title: In vivo proton magnetic resonance imaging and localized spectroscopic analysis of polycystic kidney disease in DBA/2FG-pyc mice.
Volume: 9
Issue: 3
Pages: 429-34
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Publication
18180309 | J:131142
First Author: Meyer-Bahlburg A
Year: 2008
Journal: J Exp Med
Title: Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation.
Volume: 205
Issue: 1
Pages: 155-68
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Publication
14688127 | J:87817
First Author: Gyetko MR
Year: 2004
Journal: Infect Immun
Title: Urokinase-deficient mice fail to generate a type 2 immune response following schistosomal antigen challenge.
Volume: 72
Issue: 1
Pages: 461-7
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Publication
20308364 | J:159176
First Author: Henderson RB
Year: 2010
Journal: J Exp Med
Title: A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.
Volume: 207
Issue: 4
Pages: 837-53
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Publication
10429672 | J:115295
First Author: Loder F
Year: 1999
Journal: J Exp Med
Title: B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.
Volume: 190
Issue: 1
Pages: 75-89
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Publication
22057631 | J:179824
First Author: Shahaf G
Year: 2012
Journal: Eur J Immunol
Title: Lyn deficiency affects B-cell maturation as well as survival.
Volume: 42
Issue: 2
Pages: 511-21
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Publication
11739500 | J:112116
First Author: Allman D
Year: 2001
Journal: J Immunol
Title: Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation.
Volume: 167
Issue: 12
Pages: 6834-40
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Publication
21928281 | J:179511
First Author: Gross AJ
Year: 2011
Journal: Eur J Immunol
Title: Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.
Volume: 41
Issue: 12
Pages: 3645-55
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Publication
23585893 | J:200584
First Author: Badano MN
Year: 2013
Journal: PLoS One
Title: B-cell lymphopoiesis is regulated by cathepsin L.
Volume: 8
Issue: 4
Pages: e61347
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Publication
28264879 | J:241512
First Author: de Aguiar Vallim TQ
Year: 2017
Journal: J Lipid Res
Title: ABCG1 regulates pulmonary surfactant metabolism in mice and men.
Volume: 58
Issue: 5
Pages: 941-954
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Publication
12574334 | J:81806
First Author: Dalwadi H
Year: 2003
Journal: J Immunol
Title: B cell developmental requirement for the G alpha i2 gene.
Volume: 170
Issue: 4
Pages: 1707-15
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Publication
29206970 | J:252782
First Author: Urao N
Year: 2017
Journal: Hum Mol Genet
Title: Thrombospondin-1 and disease progression in dysferlinopathy.
Volume: 26
Issue: 24
Pages: 4951-4960
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Publication
9390273 | J:44588
 
First Author: Lai WC
Journal: Nat Immun
Title: Natural resistance to Mycoplasma pulmonis infection in mice: host resistance gene(s) map to chromosome 4.
Volume: 15
Issue: 5
Pages: 241-8
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Publication
16301744 | J:118846
First Author: Craxton A
Year: 2005
Journal: J Exp Med
Title: BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.
Volume: 202
Issue: 10
Pages: 1363-74
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Publication
18566428 | J:137396
First Author: Osterholzer JJ
Year: 2008
Journal: J Immunol
Title: CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans.
Volume: 181
Issue: 1
Pages: 610-20
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Publication
29139538 | J:251722
First Author: Summers MA
Year: 2017
Journal: Int J Dev Biol
Title: Limitations of the Pax7-creERT2 transgene for driving deletion of Nf1 in adult mouse muscle.
Volume: 61
Issue: 8-9
Pages: 531-536
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Publication
17650334 | J:126543
 
First Author: Taylor JA 3rd
Year: 2007
Journal: BMC Cancer
Title: Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice.
Volume: 7
Pages: 135
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Publication
31887305 | J:296798
 
First Author: Nemeth CL
Year: 2020
Journal: Exp Neurol
Title: Neuronal ablation of mt-AspRS in mice induces immune pathway activation prior to severe and progressive cortical and behavioral disruption.
Volume: 326
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