| Type |
Details |
Score |
| Publication |
| First Author: |
Nagata Y |
| Year: |
1995 |
| Journal: |
J Biochem |
| Title: |
A 6-kb upstream region of the human transthyretin gene can direct developmental, tissue-specific, and quantitatively normal expression in transgenic mouse. |
| Volume: |
117 |
| Issue: |
1 |
| Pages: |
169-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu YC |
| Year: |
2021 |
| Journal: |
Mol Ther |
| Title: |
Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation. |
| Volume: |
29 |
| Issue: |
1 |
| Pages: |
376-395 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fukuda T |
| Year: |
2018 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Short-term administration of iso-α-acids increases transthyretin transcription in the hippocampus. |
| Volume: |
507 |
| Issue: |
1-4 |
| Pages: |
471-475 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kennel SJ |
| Year: |
2024 |
| Journal: |
PLoS One |
| Title: |
Preclinical evaluation of Tc-99m p5+14 peptide for SPECT detection of cardiac amyloidosis. |
| Volume: |
19 |
| Issue: |
4 |
| Pages: |
e0301756 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mazzei G |
| Year: |
2021 |
| Journal: |
Aging Cell |
| Title: |
A high-fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the AppNL-F/NL-F knock-in mouse model. |
| Volume: |
20 |
| Issue: |
8 |
| Pages: |
e13429 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuzaki T |
| Year: |
2017 |
| Journal: |
Aging Cell |
| Title: |
Transthyretin deposition promotes progression of osteoarthritis. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
1313-1322 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perrone-Bizzozero NI |
| Year: |
2011 |
| Journal: |
ASN Neuro |
| Title: |
Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice. |
| Volume: |
3 |
| Issue: |
5 |
| Pages: |
259-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takaoka Y |
| Year: |
2004 |
| Journal: |
Am J Pathol |
| Title: |
Cysteine 10 is a key residue in amyloidogenesis of human transthyretin Val30Met. |
| Volume: |
164 |
| Issue: |
1 |
| Pages: |
337-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yahoo N |
| Year: |
2016 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Forced expression of Hnf4a induces hepatic gene activation through directed differentiation. |
| Volume: |
476 |
| Issue: |
4 |
| Pages: |
313-318 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fonseca Costa SS |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
e0169615 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lisowski P |
| Year: |
2013 |
| Journal: |
J Mol Neurosci |
| Title: |
Effects of chronic stress on prefrontal cortex transcriptome in mice displaying different genetic backgrounds. |
| Volume: |
50 |
| Issue: |
1 |
| Pages: |
33-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wen J |
| Year: |
2021 |
| Journal: |
Transgenic Res |
| Title: |
Methylation silencing and reactivation of exogenous genes in lentivirus-mediated transgenic mice. |
| Volume: |
30 |
| Issue: |
1 |
| Pages: |
63-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slamova I |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
7112 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sivasubramaniyam T |
| Year: |
2017 |
| Journal: |
JCI Insight |
| Title: |
Hepatic JAK2 protects against atherosclerosis through circulating IGF-1. |
| Volume: |
2 |
| Issue: |
14 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pires KM |
| Year: |
2019 |
| Journal: |
Antioxid Redox Signal |
| Title: |
Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling. |
| Volume: |
31 |
| Issue: |
6 |
| Pages: |
444-457 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okamoto H |
| Year: |
2006 |
| Journal: |
J Clin Invest |
| Title: |
Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. |
| Volume: |
116 |
| Issue: |
3 |
| Pages: |
775-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Plum L |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
InsR/FoxO1 signaling curtails hypothalamic POMC neuron number. |
| Volume: |
7 |
| Issue: |
2 |
| Pages: |
e31487 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gatza CE |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
Altered mammary gland development in the p53+/m mouse, a model of accelerated aging. |
| Volume: |
313 |
| Issue: |
1 |
| Pages: |
130-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nowotschin S |
| Year: |
2013 |
| Journal: |
Genes Dev |
| Title: |
The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. |
| Volume: |
27 |
| Issue: |
9 |
| Pages: |
997-1002 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moore R |
| Year: |
2014 |
| Journal: |
Mol Cell Biol |
| Title: |
The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
560-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schmidt PJ |
| Year: |
2008 |
| Journal: |
Cell Metab |
| Title: |
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. |
| Volume: |
7 |
| Issue: |
3 |
| Pages: |
205-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dodington DW |
| Year: |
2021 |
| Journal: |
JCI Insight |
| Title: |
JAK2-IGF1 axis in osteoclasts regulates postnatal growth in mice. |
| Volume: |
6 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kitamura YI |
| Year: |
2005 |
| Journal: |
Cell Metab |
| Title: |
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. |
| Volume: |
2 |
| Issue: |
3 |
| Pages: |
153-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lawrence NJ |
| Year: |
2008 |
| Journal: |
DNA Repair (Amst) |
| Title: |
A neurological phenotype in mice with DNA repair gene Ercc1 deficiency. |
| Volume: |
7 |
| Issue: |
2 |
| Pages: |
281-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gupta D |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Peroxisome proliferator-activated receptor γ (PPARγ) and its target genes are downstream effectors of FoxO1 protein in islet β-cells: mechanism of β-cell compensation and failure. |
| Volume: |
288 |
| Issue: |
35 |
| Pages: |
25440-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawamura N |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. |
| Volume: |
31 |
| Issue: |
10 |
| Pages: |
107733 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ttr/Ttr |
| Background: |
B6.Cg-Ttr/Ttr |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-Bgeo/GFP)21Lbe/? Meox2/Meox2<+> Tg(Ttr-RFP)1Hadj/? |
| Background: |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
González-Marrero I |
| Year: |
2015 |
| Journal: |
Front Cell Neurosci |
| Title: |
Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer's disease. |
| Volume: |
9 |
|
| Pages: |
17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanos R |
| Year: |
2012 |
| Journal: |
Toxicol Sci |
| Title: |
Role of the Ah receptor in homeostatic control of fatty acid synthesis in the liver. |
| Volume: |
129 |
| Issue: |
2 |
| Pages: |
372-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakae J |
| Year: |
2002 |
| Journal: |
Nat Genet |
| Title: |
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. |
| Volume: |
32 |
| Issue: |
2 |
| Pages: |
245-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodriguez AM |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula. |
| Volume: |
432 |
| Issue: |
1 |
| Pages: |
98-124 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin HV |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons. |
| Volume: |
59 |
| Issue: |
2 |
| Pages: |
337-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoon Y |
| Year: |
2012 |
| Journal: |
Dev Biol |
| Title: |
Conditional Aurora A deficiency differentially affects early mouse embryo patterning. |
| Volume: |
371 |
| Issue: |
1 |
| Pages: |
77-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoon Y |
| Year: |
2015 |
| Journal: |
Dev Biol |
| Title: |
Extra-embryonic Wnt3 regulates the establishment of the primitive streak in mice. |
| Volume: |
403 |
| Issue: |
1 |
| Pages: |
80-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nowotschin S |
| Year: |
2019 |
| Journal: |
Nature |
| Title: |
The emergent landscape of the mouse gut endoderm at single-cell resolution. |
| Volume: |
569 |
| Issue: |
7756 |
| Pages: |
361-367 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamamura K |
| Year: |
1987 |
| Journal: |
Dev Genet |
| Title: |
Tissue-specific and developmental expression of human transthyretin gene in transgenic mice. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
195-205 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Junge N |
| Year: |
2018 |
| Journal: |
World J Hepatol |
| Title: |
Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model. |
| Volume: |
10 |
| Issue: |
2 |
| Pages: |
277-286 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qian X |
| Year: |
1995 |
| Journal: |
Mol Cell Biol |
| Title: |
Decreased expression of hepatocyte nuclear factor 3 alpha during the acute-phase response influences transthyretin gene transcription. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
1364-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Du M |
| Year: |
2017 |
| Journal: |
Mol Vis |
| Title: |
Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. |
| Volume: |
23 |
|
| Pages: |
185-197 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Migeotte I |
| Year: |
2011 |
| Journal: |
Development |
| Title: |
Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo. |
| Volume: |
138 |
| Issue: |
14 |
| Pages: |
3011-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madabhushi M |
| Year: |
2011 |
| Journal: |
Dev Cell |
| Title: |
Anterior visceral endoderm directs ventral morphogenesis and placement of head and heart via BMP2 expression. |
| Volume: |
21 |
| Issue: |
5 |
| Pages: |
907-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Biechele S |
| Year: |
2013 |
| Journal: |
Development |
| Title: |
Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. |
| Volume: |
140 |
| Issue: |
14 |
| Pages: |
2961-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mao J |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure. |
| Volume: |
137 |
| Issue: |
18 |
| Pages: |
3079-88 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Senft AD |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
1089 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okamoto H |
| Year: |
2004 |
| Journal: |
J Clin Invest |
| Title: |
Transgenic rescue of insulin receptor-deficient mice. |
| Volume: |
114 |
| Issue: |
2 |
| Pages: |
214-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kwon GS |
| Year: |
2008 |
| Journal: |
Dev Cell |
| Title: |
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. |
| Volume: |
15 |
| Issue: |
4 |
| Pages: |
509-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Migeotte I |
| Year: |
2010 |
| Journal: |
PLoS Biol |
| Title: |
Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e1000442 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gredler ML |
| Year: |
2023 |
| Journal: |
Dev Cell |
| Title: |
Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm. |
| Volume: |
58 |
| Issue: |
11 |
| Pages: |
933-950.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Omelchenko T |
| Year: |
2014 |
| Journal: |
Genes Dev |
| Title: |
β-Pix directs collective migration of anterior visceral endoderm cells in the early mouse embryo. |
| Volume: |
28 |
| Issue: |
24 |
| Pages: |
2764-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mutant Mouse Regional Resource Centers |
| Year: |
2004 |
| Journal: |
Unpublished |
| Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
European Mouse Mutant Archive |
| Year: |
2003 |
| Journal: |
Unpublished |
| Title: |
Information obtained from the European Mouse Mutant Archive (EMMA) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
| Year: |
2005 |
| Journal: |
Database Download |
| Title: |
MGI download of GENSAT transgene data |
|
|
|
|
•
•
•
•
•
|