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Search results 1001 to 1100 out of 1467 for Wap

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Strain
MGI:6770012 | C57BL/6JGpt-Wfdc5<em6Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6770015 | C57BL/6JGpt-Wfdc8<em2Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7718322 | C57BL/6JSmoc-Wfdc13<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7718323 | C57BL/6JSmoc-Wfdc2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7382530 | C57BL/6JGpt-Wfdc2<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7767700 | C57BL/6JSmoc-Wfdc9<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Wfdc1/Wfdc1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wfdc18/Wfdc18
Background: C57BL/6N-Wfdc18/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wfdc2/Wfdc2<+>
Background: C57BL/6NTac-Wfdc2/H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wfdc1/Wfdc1<+>
Background: C57BL/6N-Wfdc1/Ucd
Zygosity: ht
Has Mutant Allele: true
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Publication
9367891 | J:44218
First Author: Lee M
Year: 1997
Journal: Biochem Biophys Res Commun
Title: EGF inhibits expression of WDNM1 and sulfated glycoprotein-2 genes in mammary epithelial cells.
Volume: 240
Issue: 1
Pages: 104-7
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Strain
MGI:5576785 | FVB/N-Tg(Wap-Hgf)402Mig
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5496418 | FVB-Tg(Wap-Hgf)402Mig/Cnbc
Attribute String: coisogenic, mutant strain, transgenic
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Publication
14627990 | J:86776
First Author: Gallego MI
Year: 2003
Journal: Oncogene
Title: Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.
Volume: 22
Issue: 52
Pages: 8498-508
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Publication
16424394 | J:108378
First Author: Cao R
Year: 2006
Journal: Blood
Title: Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action.
Volume: 107
Issue: 9
Pages: 3531-6
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Allele
Tg(WapTAg)1Knw | MGI:3040314
Name: transgene insertion 1, Barbara B Knowles
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rr328<em1Hysh> | MGI:7408237
Name: regulatory region 328; endonuclease-mediated mutation 1, Ha Youn Shin
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(Wap-Hgf)402Mig/?
Background: FVB/N-Tg(Wap-Hgf)402Mig
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Wap-Hgf)402Mig/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:6335407 | C57BL/6N-A<tm1Brd> Wfdc18<tm1a(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7853459 | C57BL/6N-A<tm1Brd> Wfdc18<tm1a(KOMP)Wtsi>/WtsiH
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6345162 | C57BL/6N-A<tm1Brd> Wfdc18<tm1a(KOMP)Wtsi>/Mmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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HT Experiment
GSE121438 | Lineage-specific super-enhancer activates genes in a promoter-selective manner
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Allele
Tg(Wap-Tag)8Gmn | MGI:3621350
Name: transgene insertion 8, A Graessmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rr328<em1Mam> | MGI:7408213
Name: regulatory region 328; endonuclease-mediated mutation 1, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr328<em3Mam> | MGI:7408216
Name: regulatory region 328; endonuclease-mediated mutation 3, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr329<em1Mam> | MGI:7408217
Name: regulatory region 329; endonuclease-mediated mutation 1, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr330<em1Mam> | MGI:7408220
Name: regulatory region 330; endonuclease-mediated mutation 1, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr328<em4Hysh> | MGI:7408240
Name: regulatory region 328; endonuclease-mediated mutation 4, Ha Youn Shin
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr328<em2Hysh> | MGI:7408238
Name: regulatory region 328; endonuclease-mediated mutation 2, Ha Youn Shin
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr328<em3Hysh> | MGI:7437889
Name: regulatory region 328; endonuclease-mediated mutation 3, Ha Youn Shin
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr330<em2Mam> | MGI:7438006
Name: regulatory region 330; endonuclease-mediated mutation 2, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Publication
7550308 | J:28391
First Author: Marquis ST
Year: 1995
Journal: Nat Genet
Title: The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.
Volume: 11
Issue: 1
Pages: 17-26
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Publication
15060002 | J:95646
First Author: Puente XS
Year: 2004
Journal: Genome Res
Title: A genomic analysis of rat proteases and protease inhibitors.
Volume: 14
Issue: 4
Pages: 609-22
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Genotype
Genotype
Symbol: Wfdc2/Wfdc2
Background: involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: ht
Has Mutant Allele: true
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Publication
9859214 | J:53175
First Author: Hüsler MR
Year: 1998
Journal: Transgenic Res
Title: Lactation-induced WAP-SV40 Tag transgene expression in C57BL/6J mice leads to mammary carcinoma.
Volume: 7
Issue: 4
Pages: 253-63
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Publication
8620493 | J:33193
First Author: Gallahan D
Year: 1996
Journal: Cancer Res
Title: Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
Volume: 56
Issue: 8
Pages: 1775-85
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Publication
8390039 | J:56330
First Author: Tzeng YJ
Year: 1993
Journal: Oncogene
Title: Breast cancer formation in transgenic animals induced by the whey acidic protein SV40 T antigen (WAP-SV-T) hybrid gene.
Volume: 8
Issue: 7
Pages: 1965-71
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Publication
30089273 | J:361278
First Author: Giraddi RR
Year: 2018
Journal: Cell Rep
Title: Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development.
Volume: 24
Issue: 6
Pages: 1653-1666.e7
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Strain
MGI:2164339 | C57BL/6J-Tg(WapTAg)1Knw/J
Attribute String: mutant strain, transgenic
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Allele
Tg(Wap-cre)1Gsc | MGI:3527260
Name: transgene insertion 1, Gunther Schutz
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:6144441 | B6.Cg-Tg(Wap-Tag)8Gmn/Nci
Attribute String: Not specified
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Strain
MGI:4835935 | NMRI-Tg(Wap-Tag)8Gmn/Kctt
Attribute String: mutant stock, transgenic
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Publication
8601427 | J:332758
First Author: Tzeng YJ
Year: 1996
Journal: FEBS Lett
Title: The SV40 T-antigen induces premature apoptotic mammary gland involution during late pregnancy in transgenic mice.
Volume: 380
Issue: 3
Pages: 215-8
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Publication
17410534 | J:125401
First Author: Klein A
Year: 2007
Journal: Int J Cancer
Title: Comparison of gene expression data from human and mouse breast cancers: identification of a conserved breast tumor gene set.
Volume: 121
Issue: 3
Pages: 683-8
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Publication
8788028 | J:133843
First Author: Li M
Year: 1996
Journal: Cell Growth Differ
Title: Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells.
Volume: 7
Issue: 1
Pages: 3-11
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Publication
9572491 | J:332733
First Author: Tzeng YJ
Year: 1998
Journal: Oncogene
Title: SV40 T/t-antigen induces premature mammary gland involution by apoptosis and selects for p53 missense mutation in mammary tumors.
Volume: 16
Issue: 16
Pages: 2103-14
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Allele
Tg(Wap-Tsg101)4389Kuw | MGI:3710126
Name: transgene insertion 4389, Kay-Uwe Wagner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Wap<em1(cre)Smoc> | MGI:6758076
Name: whey acidic protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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Allele
Rr328<em2Mam> | MGI:7408214
Name: regulatory region 328; endonuclease-mediated mutation 2, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr328<tm1Mam> | MGI:7408215
Name: regulatory region 328; targeted mutation 1, Lothar Hennighausen
Allele Type: Targeted
Attribute String: Modified regulatory region
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Allele
Rr329<em2Mam> | MGI:7408218
Name: regulatory region 329; endonuclease-mediated mutation 2, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr329<em3Mam> | MGI:7408219
Name: regulatory region 329; endonuclease-mediated mutation 3, Lothar Hennighausen
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Tg(WapTAg)1Knw/?
Background: C57BL/6J-Tg(WapTAg)1Knw/J
Zygosity: ot
Has Mutant Allele: true
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Publication
3136918 | -
First Author: Dear TN
Year: 1988
Journal: Cancer Res
Title: Differential expression of a novel gene, WDNM1, in nonmetastatic rat mammary adenocarcinoma cells.
Volume: 48
Issue: 18
Pages: 5203-9
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Publication
1913827 | -
First Author: Legouis R
Year: 1991
Journal: Cell
Title: The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules.
Volume: 67
Issue: 2
Pages: 423-35
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Publication
2394696 | -
First Author: Wiedow O
Year: 1990
Journal: J Biol Chem
Title: Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence.
Volume: 265
Issue: 25
Pages: 14791-5
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Publication
2324101 | -
First Author: Coronel CE
Year: 1990
Journal: J Biol Chem
Title: Purification and structure of caltrin-like proteins from seminal vesicle of the guinea pig.
Volume: 265
Issue: 12
Pages: 6854-9
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Publication
11965550 | -
First Author: Bingle L
Year: 2002
Journal: Oncogene
Title: The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.
Volume: 21
Issue: 17
Pages: 2768-73
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Protein Domain
IPR008197 | WAP_dom
Type: Domain
Description: The four-disulfide core (4-DSC) or WAP domain comprises eight cysteine residues involved in disulfide bonds in a conserved arrangement []. The four disulphide core containing Whey Acidic Proteins (WAP) are the major whey proteins in the milk of many mammals and are considered to be the prototypic members of the family. However the WAP domain is not exclusive to WAP proteins, but it is found in many other proteins, a number of which have been shown to exhibit antiproteinase function [].One or more of the WAP domains occur in the WDNM1 protein, which is involved in the metastatic potential of adenocarcinomas in rats []; Kallmann syndrome protein []; caltrin-like protein II from guinea pig [], which inhibits calcium transport into spermatozoa; elafin, a serine elastase inhibitor which belongs to MEROPS inhibitor family I17 []; and papilin, a metalloendopeptidase inhibitor which belongs to MEROPS inhibitor family I2 and is effective against procollagen N-proteinase [].
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Publication
11283268 | J:68368
First Author: Vogel WF
Year: 2001
Journal: Mol Cell Biol
Title: Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development.
Volume: 21
Issue: 8
Pages: 2906-17
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Publication
12909348 | J:84763
 
First Author: Sivashanmugam P
Year: 2003
Journal: Gene
Title: Characterization of mouse Eppin and a gene cluster of similar protease inhibitors on mouse chromosome 2.
Volume: 312
Pages: 125-34
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Publication
15665292 | J:95511
First Author: Reichling T
Year: 2005
Journal: Cancer Res
Title: Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors.
Volume: 65
Issue: 1
Pages: 166-76
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Publication
30285185 | J:266979
First Author: Lee HK
Year: 2018
Journal: Nucleic Acids Res
Title: Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation.
Volume: 46
Issue: 20
Pages: 10796-10809
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Allele
Tg(WapNotch4)10Rnc | MGI:1930202
Name: transgene insertion 10, Robert Callahan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Wap-cre)11738Mam | MGI:2176167
Name: transgene insertion 11738, Lothar Hennighausen
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Wap-Mmp3)9Sym | MGI:2429538
Name: transgene insertion 9, Carolyn J Sympson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Wap-Mmp3)5Sym | MGI:2429539
Name: transgene insertion 5, Carolyn J Sympson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3716999 | FVB/N-Tg(Wap-cre)1Gsc/Ieg
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tg(Wap-cre)2Gsc | MGI:3527262
Name: transgene insertion 2, Gunther Schutz
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:4430730 | FVB/N-Tg(Wap-Tsg101)4389Kuw/Mmmh
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:3710659 | FVB/N-Tg(Wap-Tsg101)4389Kuw
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Tg(WAPT121)66Tvd | MGI:4940590
Name: transgene insertion 66, Terry van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Wap-Shh)119Mig | MGI:5645728
Name: transgene insertion 119, Marta I Gallego
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Wap-Shh)186Mig | MGI:5645729
Name: transgene insertion 186, Marta I Gallego
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6429790 | C57BL/6JSmoc-Wap<em1(cre)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Tg(Wap-Tsg101)4389Kuw/?
Background: FVB/N-Tg(Wap-Tsg101)4389Kuw
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Wap-cre)1Gsc/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Publication
22363625 | J:185316
First Author: Serber DW
Year: 2012
Journal: PLoS One
Title: The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner.
Volume: 7
Issue: 2
Pages: e31346
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Publication
10359639 | J:56042
 
First Author: Schalkwijk J
Year: 1999
Journal: Biochem J
Title: The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core.
Volume: 340 ( Pt 3)
Pages: 569-77
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Protein
Q8BTE6
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: false
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Protein
P97430
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: false
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Protein
Q4KXB6
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: false
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Protein
Q7M748
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: false
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Protein
Q548X8
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: false
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Protein
E9Q748
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
Q5DQQ4
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
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Publication
23920117 | J:202352
First Author: Boualia SK
Year: 2013
Journal: Dev Biol
Title: A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis.
Volume: 382
Issue: 2
Pages: 555-66
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Publication
23000969 | J:222841
First Author: García-Zaragoza E
Year: 2012
Journal: Dev Biol
Title: Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland.
Volume: 372
Issue: 1
Pages: 28-44
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Publication
9336464 | J:67925
First Author: Wagner KU
Year: 1997
Journal: Nucleic Acids Res
Title: Cre-mediated gene deletion in the mammary gland.
Volume: 25
Issue: 21
Pages: 4323-30
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Strain
MGI:2164702 | FVB/N-Tg(WapNotch4)10Rnc/J
Attribute String: mutant strain, transgenic
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Publication
16878155 | J:117838
First Author: Raafat A
Year: 2007
Journal: Oncogene
Title: Kit and PDGFR-alpha activities are necessary for Notch4/Int3-induced tumorigenesis.
Volume: 26
Issue: 5
Pages: 662-72
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Publication
15531924 | J:94961
First Author: Raafat A
Year: 2004
Journal: Oncogene
Title: Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh).
Volume: 23
Issue: 58
Pages: 9401-7
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Strain
MGI:2165113 | B6129-Tg(Wap-cre)11738Mam/J
Attribute String: mutant strain, transgenic
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Strain
MGI:3618698 | B6.Cg-Tg(Wap-cre)11738Mam/Nci
Attribute String: mutant strain, transgenic, congenic
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Strain
MGI:4359076 | B6;129-Tg(Wap-cre)11738Mam
Attribute String: mutant stock, transgenic
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Strain
MGI:3579550 | B6129-Tg(Wap-cre)11738Mam/H
Attribute String: transgenic, mutant stock
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Strain
MGI:3818513 | B6.Cg-Tg(Wap-cre)11738Mam/JKnwJ
Attribute String: congenic, transgenic
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Strain
MGI:4399068 | B6.Cg-Tg(Wap-cre)11738Mam/JKnwPea
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:6220438 | 129S2.Cg-Tg(Wap-cre)11738Mam
Attribute String: transgenic, mutant strain, congenic
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