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Hits by Pathway

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Hits by Strain

Type Details Score
Strain
Attribute String: chromosome aberration, translocation
Strain
Attribute String: congenic, mutant strain
Strain
Attribute String: congenic, spontaneous mutation
Strain
Attribute String: chromosome aberration, mutant stock, translocation
Strain
Attribute String: mutant strain
Strain
Attribute String: chromosome aberration, translocation
Strain
Attribute String: chromosome aberration, mutant strain, translocation
Strain
Attribute String: chromosome aberration, mutant stock, translocation
Strain
Attribute String: chromosome aberration, mutant strain, translocation
Strain
Attribute String: congenic, mutant strain
Genotype
Symbol: a/a
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: a/a
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: a/a
Background: involves: C3HeB/FeJLe * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Rivera JF
Year: 2011
Journal: Cell Death Differ
Title: Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions.
Volume: 18
Issue: 3
Pages: 415-26
GO Term
Publication
First Author: Geisler JG
Year: 2002
Journal: Diabetes
Title: Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.
Volume: 51
Issue: 7
Pages: 2158-69
Publication
First Author: Chang-Yeh A
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: The mouse intracisternal A particle-promoted placental gene retrotransposition is mouse-strain-specific.
Volume: 90
Issue: 1
Pages: 292-6
Publication
First Author: Duhl DM
Year: 1994
Journal: Nat Genet
Title: Neomorphic agouti mutations in obese yellow mice.
Volume: 8
Issue: 1
Pages: 59-65
Publication
First Author: Westwell-Roper CY
Year: 2014
Journal: Diabetes
Title: Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.
Volume: 63
Issue: 5
Pages: 1698-711
Publication
First Author: Wolff GL
Year: 1978
Journal: J Hered
Title: Phaeomelanin synthesis and obesity in mice. Interaction of the viable yellow (Avy) and sombre (eso) mutations.
Volume: 69
Issue: 5
Pages: 295-8
Publication
First Author: Bergmann C
Year: 2008
Journal: Am J Hum Genet
Title: Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia.
Volume: 82
Issue: 4
Pages: 959-70
Publication
First Author: Kim MH
Year: 2016
Journal: J Lipid Res
Title: Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice.
Volume: 57
Issue: 6
Pages: 969-79
Publication
First Author: Wolff GL
Year: 1999
Journal: Physiol Genomics
Title: Physiological consequences of ectopic agouti gene expression: the yellow obese mouse syndrome.
Volume: 1
Issue: 3
Pages: 151-63
Publication
First Author: Knapp PE
Year: 2009
Journal: Neurosci Lett
Title: Cell-specific loss of kappa-opioid receptors in oligodendrocytes of the dysmyelinating jimpy mouse.
Volume: 451
Issue: 2
Pages: 114-8
Publication  
First Author: Nakashima A
Year: 2019
Journal: Science
Title: Structured spike series specify gene expression patterns for olfactory circuit formation.
Volume: 365
Issue: 6448
Publication
First Author: Blizinsky KD
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub.
Volume: 113
Issue: 30
Pages: 8520-5
Publication
First Author: Westwell-Roper CY
Year: 2015
Journal: Diabetologia
Title: IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
Volume: 58
Issue: 3
Pages: 575-85
Publication
First Author: Mustonen T
Year: 2004
Journal: Development
Title: Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages.
Volume: 131
Issue: 20
Pages: 4907-19
Publication
First Author: Yamago G
Year: 2001
Journal: Arch Dermatol Res
Title: Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice.
Volume: 293
Issue: 9
Pages: 435-41
Gene
Type: gene
Organism: human
Publication
First Author: Boran T
Year: 2005
Journal: J Dent Res
Title: Increased apoptosis during morphogenesis of the lower cheek teeth in tabby/EDA mice.
Volume: 84
Issue: 3
Pages: 228-33
Publication
First Author: Rosenfeld CS
Year: 2010
Journal: Biol Reprod
Title: Animal models to study environmental epigenetics.
Volume: 82
Issue: 3
Pages: 473-88
Publication
First Author: Heston WE
Year: 1971
Journal: Int J Cancer
Title: Mammary tumors, plaques, and hyperplastic alveolar nodules in various combinations of mouse inbred strains and the different lines of the mammary tumor virus.
Volume: 7
Issue: 1
Pages: 141-8
Publication
First Author: Wolff GL
Year: 1999
Journal: Proc Soc Exp Biol Med
Title: Caloric restriction abolishes enhanced metabolic efficiency induced by ectopic agouti protein in yellow mice.
Volume: 221
Issue: 2
Pages: 99-104
Publication
First Author: WOLFF GL
Year: 1965
Journal: Science
Title: BODY COMPOSITION AND COAT COLOR CORRELATION IN DIFFERENT PHENOTYPES OF "VIABLE YELLOW" MICE.
Volume: 147
Issue: 3662
Pages: 1145-7
Publication
First Author: Galbraith DB
Year: 1974
Journal: J Hered
Title: Aberrant regulation of the Agouti pigment pattern in the viable yellow mouse.
Volume: 65
Issue: 3
Pages: 137-40
Publication
First Author: Hansen LA
Year: 1998
Journal: Carcinogenesis
Title: Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TGxAC mice.
Volume: 19
Issue: 10
Pages: 1837-45
Publication  
First Author: Phillips RJS
Year: 1959
Journal: Mouse News Lett
Title: au - agouti umbrous
Volume: 21
Pages: 39
GXD Expression      
Probe: MGI:3772824
Assay Type: RT-PCR
Annotation Date: 2008-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3772848
Age: postnatal adult
Specimen Label: A
Detected: true
Specimen Num: 7
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Probst FJ
Year: 2008
Journal: J Hered
Title: Genotype, phenotype, and karyotype correlation in the XO mouse model of Turner Syndrome.
Volume: 99
Issue: 5
Pages: 512-7
DO Term
Publication
First Author: Factor DC
Year: 2020
Journal: Cell
Title: Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS.
Volume: 181
Issue: 2
Pages: 382-395.e21
MP Term
Publication
First Author: Poole TW
Year: 1980
Journal: Dev Biol
Title: Dermal-epidermal interactions and the action of alleles at the agouti locus in the mouse. II. The viable yellow (Avy) and mottled agouti (am) alleles.
Volume: 80
Issue: 2
Pages: 495-500
Publication
First Author: Yong J
Year: 2019
Journal: Sci Rep
Title: Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene.
Volume: 9
Issue: 1
Pages: 4269
Publication
First Author: Peng J
Year: 2002
Journal: J Biol Chem
Title: Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype.
Volume: 277
Issue: 46
Pages: 44285-91
Publication
First Author: Peng J
Year: 2006
Journal: J Neurosci
Title: Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration.
Volume: 26
Issue: 45
Pages: 11644-51
Publication
First Author: Smith DE
Year: 2003
Journal: J Neurocytol
Title: Ultrastructural organization of GABA-like immunoreactive profiles in the weaver substantia nigra.
Volume: 32
Issue: 3
Pages: 293-303
Publication  
First Author: Cattanach BM
Year: 1987
Journal: Mouse News Lett
Title: Agouti locus mutations at Harwell
Volume: 77
Pages: 123-125
Publication
First Author: Esibizione D
Year: 2008
Journal: Gene
Title: Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.
Volume: 427
Issue: 1-2
Pages: 42-6
Publication
First Author: Aberg T
Year: 2004
Journal: Dev Biol
Title: Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis.
Volume: 270
Issue: 1
Pages: 76-93
Publication
First Author: Dollé P
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.
Volume: 90
Issue: 16
Pages: 7666-70
Publication  
First Author: Siracusa LD
Year: 1991
Journal: Ann N Y Acad Sci
Title: Genomic organization and molecular genetics of the agouti locus in the mouse.
Volume: 642
Pages: 419-30
DO Term
DO Term
Publication
First Author: Stutman O
Year: 1979
Journal: Exp Cell Biol
Title: Spontaneous tumors in nude mice: effect of the viable yellow gene.
Volume: 47
Issue: 2
Pages: 129-35
GXD Expression
Probe: MGI:6316607
Assay Type: RNA in situ
Annotation Date: 2019-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6316616
Age: embryonic day 13.5
Image: 7 E13.5 A
Note: Expression is in intravascular cells in a cerebral vein. Expression is also seen in a vein near the thymus (panel D) and is absent in other vessels.
Specimen Label: 7 E13.5 A
Detected: true
Specimen Num: 11
Publication  
First Author: Dickie MM
Year: 1966
Journal: Mouse News Lett
Title: Intermediate yellow
Volume: 34
Pages: 30
Publication      
First Author: Donahue LR
Year: 1999
Journal: MGI Direct Data Submission
Title: The Jackson Laboratory Mouse Mutant Resource 1999 Mutation Reports
Publication
First Author: Visel A
Year: 2010
Journal: Nature
Title: Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.
Volume: 464
Issue: 7287
Pages: 409-12
Publication
First Author: Cunningham D
Year: 2009
Journal: Mol Genet Metab
Title: Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse.
Volume: 98
Issue: 4
Pages: 356-66
GXD Expression      
Probe: MGI:3772812
Assay Type: RT-PCR
Annotation Date: 2008-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3772863
Age: postnatal adult
Specimen Label: A
Detected: true
Specimen Num: 7
Publication
First Author: Lamoreux ML
Year: 1983
Journal: J Hered
Title: Developmental interaction in the pigmentary system of mice. II. Interaction in genetically identical mice.
Volume: 74
Issue: 6
Pages: 440-442
Publication
First Author: Rybak A
Year: 2008
Journal: Nat Cell Biol
Title: A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.
Volume: 10
Issue: 8
Pages: 987-93
Publication
First Author: Silberberg R
Year: 1976
Journal: Acta Anat (Basel)
Title: Ultrastructure of articular cartilage of achondroplastic mice.
Volume: 96
Issue: 2
Pages: 162-75
Gene
Type: gene
Organism: human
Publication
First Author: Tyan ML
Year: 1993
Journal: Proc Soc Exp Biol Med
Title: Vitamin A-enhanced cleft palate susceptibility gene maps between C4 and B144 within the H-2 complex.
Volume: 202
Issue: 4
Pages: 482-6
Publication
First Author: Zhang M
Year: 2010
Journal: Science
Title: Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes.
Volume: 330
Issue: 6002
Pages: 366-9
DO Term
Publication
First Author: Bargiela A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Increased Muscleblind levels by chloroquine treatment improve myotonic dystrophy type 1 phenotypes in in vitro and in vivo models.
Volume: 116
Issue: 50
Pages: 25203-25213
Protein
Organism: Mus musculus/domesticus
Length: 598  
Fragment?: false
Publication
First Author: Lu D
Year: 1994
Journal: Nature
Title: Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.
Volume: 371
Issue: 6500
Pages: 799-802
Publication
First Author: Katchman A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart.
Volume: 114
Issue: 34
Pages: 9194-9199
Publication  
First Author: Evans EP
Year: 1978
Journal: Mouse News Lett
Title: Inversion on Chromosome 2
Volume: 58
Pages: 44-45
Publication
First Author: Nonogaki K
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Increased hypothalamic 5-HT2A receptor gene expression and effects of pharmacologic 5-HT2A receptor inactivation in obese Ay mice.
Volume: 351
Issue: 4
Pages: 1078-82
Publication
First Author: CARTER TC
Year: 1950
Journal: Heredity (Edinb)
Title: Linkage between fidget and agouti in the house mouse.
Volume: 4
Issue: 3
Pages: 373-6
Publication
First Author: Dunn LC
Year: 1936
Journal: J Genet
Title: Studies on multiple allelomorphic series in the house mouse. I. Description of agouti and albino series of allelomorphs.
Volume: 33
Issue: 3
Pages: 443-53
Publication
First Author: Chen Y
Year: 1996
Journal: Genetics
Title: Opposite orientations of an inverted duplication and allelic variation at the mouse agouti locus.
Volume: 144
Issue: 1
Pages: 265-77
Publication
First Author: Steiger LJ
Year: 2023
Journal: Cell Rep
Title: Somatic and terminal CB1 receptors are differentially coupled to voltage-gated sodium channels in neocortical neurons.
Volume: 42
Issue: 3
Pages: 112247
Publication
First Author: van Empel VP
Year: 2005
Journal: Circ Res
Title: Downregulation of apoptosis-inducing factor in harlequin mutant mice sensitizes the myocardium to oxidative stress-related cell death and pressure overload-induced decompensation.
Volume: 96
Issue: 12
Pages: e92-e101
Publication
First Author: Hamada S
Year: 2009
Journal: Diabetes
Title: Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.
Volume: 58
Issue: 6
Pages: 1321-32
Publication
First Author: Walz A
Year: 2006
Journal: Mol Cell Neurosci
Title: Disrupted compartmental organization of axons and dendrites within olfactory glomeruli of mice deficient in the olfactory cell adhesion molecule, OCAM.
Volume: 32
Issue: 1-2
Pages: 1-14
Publication
First Author: Paul J
Year: 2018
Journal: Mucosal Immunol
Title: IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5.
Volume: 11
Issue: 2
Pages: 427-436
Publication
First Author: Lu W
Year: 2002
Journal: Development
Title: Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator.
Volume: 129
Issue: 8
Pages: 2043-50