| Type |
Details |
Score |
| Publication |
| First Author: |
Rotgers E |
| Year: |
2014 |
| Journal: |
Cell Death Dis |
| Title: |
Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells. |
| Volume: |
5 |
|
| Pages: |
e1274 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hazra R |
| Year: |
2014 |
| Journal: |
Endocrinology |
| Title: |
In vivo actions of the Sertoli cell glucocorticoid receptor. |
| Volume: |
155 |
| Issue: |
3 |
| Pages: |
1120-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abel MH |
| Year: |
2008 |
| Journal: |
Endocrinology |
| Title: |
Spermatogenesis and sertoli cell activity in mice lacking sertoli cell receptors for follicle-stimulating hormone and androgen. |
| Volume: |
149 |
| Issue: |
7 |
| Pages: |
3279-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
O'Shaughnessy PJ |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Testicular development in mice lacking receptors for follicle stimulating hormone and androgen. |
| Volume: |
7 |
| Issue: |
4 |
| Pages: |
e35136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bertoldo MJ |
| Year: |
2016 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. |
| Volume: |
423 |
|
| Pages: |
96-112 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Gendt K |
| Year: |
2005 |
| Journal: |
Endocrinology |
| Title: |
Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor. |
| Volume: |
146 |
| Issue: |
9 |
| Pages: |
4117-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Willems A |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
e14168 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang QX |
| Year: |
2012 |
| Journal: |
Asian J Androl |
| Title: |
Identification of testosterone-/androgen receptor-regulated genes in mouse Sertoli cells. |
| Volume: |
14 |
| Issue: |
2 |
| Pages: |
294-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
León NY |
| Year: |
2024 |
| Journal: |
iScience |
| Title: |
Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. |
| Volume: |
27 |
| Issue: |
5 |
| Pages: |
109629 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Geng Q |
| Year: |
2017 |
| Journal: |
Mol Med Rep |
| Title: |
Alanine and arginine rich domain containing protein, Aard, is directly regulated by androgen receptor in mouse Sertoli cells. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
352-358 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cao C |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Single-Cell RNA Sequencing Defines the Regulation of Spermatogenesis by Sertoli-Cell Androgen Signaling. |
| Volume: |
9 |
|
| Pages: |
763267 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Gendt K |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. |
| Volume: |
101 |
| Issue: |
5 |
| Pages: |
1327-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang RS |
| Year: |
2006 |
| Journal: |
Endocrinology |
| Title: |
Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes. |
| Volume: |
147 |
| Issue: |
12 |
| Pages: |
5624-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang XX |
| Year: |
2013 |
| Journal: |
J Exp Med |
| Title: |
Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection. |
| Volume: |
210 |
| Issue: |
8 |
| Pages: |
1559-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mou L |
| Year: |
2013 |
| Journal: |
Biol Reprod |
| Title: |
Identification of Ube2b as a novel target of androgen receptor in mouse sertoli cells. |
| Volume: |
89 |
| Issue: |
2 |
| Pages: |
32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walters KA |
| Year: |
2012 |
| Journal: |
Biol Reprod |
| Title: |
Targeted loss of androgen receptor signaling in murine granulosa cells of preantral and antral follicles causes female subfertility. |
| Volume: |
87 |
| Issue: |
6 |
| Pages: |
151 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang B |
| Year: |
2016 |
| Journal: |
Mol Reprod Dev |
| Title: |
RFX1 maintains testis cord integrity by regulating the expression of Itga6 in male mouse embryos. |
| Volume: |
83 |
| Issue: |
7 |
| Pages: |
606-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De Gendt K |
| Year: |
2011 |
| Journal: |
Biol Reprod |
| Title: |
Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells. |
| Volume: |
85 |
| Issue: |
5 |
| Pages: |
934-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng W |
| Year: |
2019 |
| Journal: |
Genes (Basel) |
| Title: |
DDB1 Regulates Sertoli Cell Proliferation and Testis Cord Remodeling by TGFβ Pathway. |
| Volume: |
10 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ophoff J |
| Year: |
2009 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone. |
| Volume: |
378 |
| Issue: |
1 |
| Pages: |
139-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu R |
| Year: |
2019 |
| Journal: |
Cell Death Dis |
| Title: |
The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood-testis barrier and results in hypospermatogenesis. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
450 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang L |
| Year: |
2014 |
| Journal: |
Mol Reprod Dev |
| Title: |
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells. |
| Volume: |
81 |
| Issue: |
6 |
| Pages: |
514-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sridharan S |
| Year: |
2007 |
| Journal: |
Biol Reprod |
| Title: |
Proliferation of adult sertoli cells following conditional knockout of the Gap junctional protein GJA1 (connexin 43) in mice. |
| Volume: |
76 |
| Issue: |
5 |
| Pages: |
804-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Holdcraft RW |
| Year: |
2004 |
| Journal: |
Development |
| Title: |
Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids. |
| Volume: |
131 |
| Issue: |
2 |
| Pages: |
459-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiong Z |
| Year: |
2018 |
| Journal: |
Biol Reprod |
| Title: |
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis. |
| Volume: |
99 |
| Issue: |
6 |
| Pages: |
1289-1302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang W |
| Year: |
2022 |
| Journal: |
Mol Hum Reprod |
| Title: |
Bi-allelic variants in SHOC1 cause non-obstructive azoospermia with meiosis arrest in humans and mice. |
| Volume: |
28 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Levasseur A |
| Year: |
2017 |
| Journal: |
Biol Reprod |
| Title: |
Yes-associated protein and WW-containing transcription regulator 1 regulate the expression of sex-determining genes in Sertoli cells, but their inactivation does not cause sex reversal. |
| Volume: |
97 |
| Issue: |
1 |
| Pages: |
162-175 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Plekha5/Plekha5<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Plekha5/Plekha5<+> |
| Background: |
involves: 129S/SvEv * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cyp26b1/Cyp26b1 Plekha5/Plekha5<+> |
| Background: |
involves: 129S2/SvPas * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Plekha5/Plekha5<+> |
| Background: |
involves: 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Plekha5/Plekha5 |
| Background: |
involves: 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mex3b/Mex3b Plekha5/Plekha5<+> |
| Background: |
involves: C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ddb1/Ddb1 Plekha5/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ptpn11/Ptpn11 Plekha5/Plekha5<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hnrnph1/Hnrnph1 Plekha5/Plekha5<+> |
| Background: |
involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Plekha5/Plekha5<+> Sox9/Sox9 |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Plekha5/? Pum1/Pum1 |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sox9/Sox9 Plekha5/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Atrx/? Plekha5/? |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ptpn11/Ptpn11 Plekha5/Plekha5<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Utp14b/Utp14b Tg(Amh-cre)8815Reb/? |
| Background: |
involves: 129 * C3H * C57BL/6J * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Rb1/Rb1 Plekha5/Plekha5<+> |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Rb1/Rb1<+> Plekha5/Plekha5<+> |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ggps1/Ggps1<+> Plekha5/Plekha5<+> |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ggps1/Ggps1 Plekha5/Plekha5<+> |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Plekha5/Plekha5<+> Rnf20/Rnf20 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Arid4b/Arid4b Tg(Amh-cre)8815Reb/? |
| Background: |
involves: 129S7/SvEvBrd * C57BL/6J * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Nr5a1/Nr5a1 Plekha5/Plekha5<+> |
| Background: |
involves: 129S2/SvPas * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Lats1/Lats1 Lats2/Lats2 Tg(Amh-cre)8815Reb/? |
| Background: |
involves: C57BL/6 * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
448
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen SR |
| Year: |
2013 |
| Journal: |
Biol Reprod |
| Title: |
The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2. |
| Volume: |
88 |
| Issue: |
3 |
| Pages: |
56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wen Q |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. |
| Volume: |
11 |
| Issue: |
12 |
| Pages: |
e0167920 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang H |
| Year: |
2009 |
| Journal: |
Biol Reprod |
| Title: |
Overactive beta-catenin signaling causes testicular sertoli cell tumor development in the mouse. |
| Volume: |
81 |
| Issue: |
5 |
| Pages: |
842-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hurtado A |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Sertoli cell-specific ablation of miR-17-92 cluster significantly alters whole testis transcriptome without apparent phenotypic effects. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
e0197685 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rotgers E |
| Year: |
2019 |
| Journal: |
J Cell Sci |
| Title: |
Retinoblastoma protein represses E2F3 to maintain Sertoli cell quiescence in mouse testis. |
| Volume: |
132 |
| Issue: |
14 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vernet N |
| Year: |
2008 |
| Journal: |
Reproduction |
| Title: |
Retinoid X receptor beta (RXRB) expression in Sertoli cells controls cholesterol homeostasis and spermiation. |
| Volume: |
136 |
| Issue: |
5 |
| Pages: |
619-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oduwole OO |
| Year: |
2018 |
| Journal: |
J Clin Invest |
| Title: |
Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis. |
| Volume: |
128 |
| Issue: |
5 |
| Pages: |
1787-1792 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Godmann M |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
Krüppel-like factor 4 is involved in functional differentiation of testicular Sertoli cells. |
| Volume: |
315 |
| Issue: |
2 |
| Pages: |
552-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noelke J |
| Year: |
2015 |
| Journal: |
Cell Tissue Res |
| Title: |
A Sertoli cell-specific connexin43 knockout leads to altered interstitial connexin expression and increased Leydig cell numbers. |
| Volume: |
361 |
| Issue: |
2 |
| Pages: |
633-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brehm R |
| Year: |
2007 |
| Journal: |
Am J Pathol |
| Title: |
A sertoli cell-specific knockout of connexin43 prevents initiation of spermatogenesis. |
| Volume: |
171 |
| Issue: |
1 |
| Pages: |
19-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carette D |
| Year: |
2010 |
| Journal: |
Dev Biol |
| Title: |
Major involvement of connexin 43 in seminiferous epithelial junction dynamics and male fertility. |
| Volume: |
346 |
| Issue: |
1 |
| Pages: |
54-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chojnacka K |
| Year: |
2012 |
| Journal: |
Reprod Biol |
| Title: |
Expression of the androgen receptor in the testis of mice with a Sertoli cell specific knock-out of the connexin 43 gene (SCCx43KO(-/-)). |
| Volume: |
12 |
| Issue: |
4 |
| Pages: |
341-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rode K |
| Year: |
2018 |
| Journal: |
Reprod Biol |
| Title: |
Loss of connexin 43 in Sertoli cells provokes postnatal spermatogonial arrest, reduced germ cell numbers and impaired spermatogenesis. |
| Volume: |
18 |
| Issue: |
4 |
| Pages: |
456-466 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giese S |
| Year: |
2012 |
| Journal: |
Dis Model Mech |
| Title: |
Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice. |
| Volume: |
5 |
| Issue: |
6 |
| Pages: |
895-913 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weider K |
| Year: |
2011 |
| Journal: |
Differentiation |
| Title: |
Altered differentiation and clustering of Sertoli cells in transgenic mice showing a Sertoli cell specific knockout of the connexin 43 gene. |
| Volume: |
82 |
| Issue: |
1 |
| Pages: |
38-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hilbold E |
| Year: |
2020 |
| Journal: |
Cells |
| Title: |
Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. |
| Volume: |
9 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Staggenborg S |
| Year: |
2022 |
| Journal: |
Sci Rep |
| Title: |
Connexin43 represents an important regulator for Sertoli cell morphology, Sertoli cell nuclear ultrastructure, and Sertoli cell maturation. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
12898 |
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| Publication |
| First Author: |
Hollenbach J |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
e0198100 |
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| Publication |
| First Author: |
Morohoshi A |
| Year: |
2019 |
| Journal: |
Dev Biol |
| Title: |
The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice. |
| Volume: |
445 |
| Issue: |
2 |
| Pages: |
178-188 |
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•
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| Publication |
| First Author: |
Lei WL |
| Year: |
2021 |
| Journal: |
Cell Death Dis |
| Title: |
Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
883 |
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•
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| Publication |
| First Author: |
Hu X |
| Year: |
2015 |
| Journal: |
Sci Rep |
| Title: |
Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. |
| Volume: |
5 |
|
| Pages: |
12982 |
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•
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| Publication |
| First Author: |
Chen SR |
| Year: |
2015 |
| Journal: |
Oncotarget |
| Title: |
Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling. |
| Volume: |
6 |
| Issue: |
35 |
| Pages: |
37012-27 |
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•
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| Publication |
| First Author: |
Sun R |
| Year: |
2021 |
| Journal: |
Mol Med Rep |
| Title: |
PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis. |
| Volume: |
23 |
| Issue: |
2 |
|
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•
•
•
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| Publication |
| First Author: |
Papaioannou MD |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Sertoli cell Dicer is essential for spermatogenesis in mice. |
| Volume: |
326 |
| Issue: |
1 |
| Pages: |
250-9 |
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•
•
•
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| Publication |
| First Author: |
Feng S |
| Year: |
2023 |
| Journal: |
Development |
| Title: |
hnRNPH1 establishes Sertoli-germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice. |
| Volume: |
150 |
| Issue: |
3 |
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•
•
•
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| Publication |
| First Author: |
Zomer HD |
| Year: |
2022 |
| Journal: |
Biol Reprod |
| Title: |
Sertoli cells require TDP-43 to support spermatogenesis†. |
| Volume: |
107 |
| Issue: |
5 |
| Pages: |
1345-1359 |
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•
•
•
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| Publication |
| First Author: |
O'Donnell L |
| Year: |
2023 |
| Journal: |
PLoS One |
| Title: |
Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid. |
| Volume: |
18 |
| Issue: |
9 |
| Pages: |
e0290846 |
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•
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| Publication |
| First Author: |
Bhardwaj A |
| Year: |
2022 |
| Journal: |
Endocrinology |
| Title: |
Concordant Androgen-Regulated Expression of Divergent Rhox5 Promoters in Sertoli Cells. |
| Volume: |
163 |
| Issue: |
1 |
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•
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| Publication |
| First Author: |
O'Donnell L |
| Year: |
2021 |
| Journal: |
FASEB J |
| Title: |
Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men. |
| Volume: |
35 |
| Issue: |
3 |
| Pages: |
e21397 |
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•
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| Publication |
| First Author: |
Chang C |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. |
| Volume: |
101 |
| Issue: |
18 |
| Pages: |
6876-81 |
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•
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| Publication |
| First Author: |
Bao J |
| Year: |
2014 |
| Journal: |
PLoS Genet |
| Title: |
RAN-binding protein 9 is involved in alternative splicing and is critical for male germ cell development and male fertility. |
| Volume: |
10 |
| Issue: |
12 |
| Pages: |
e1004825 |
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•
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| Publication |
| First Author: |
Wang Y |
| Year: |
2024 |
| Journal: |
Nucleic Acids Res |
| Title: |
PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators. |
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| Publication |
| First Author: |
McKey J |
| Year: |
2020 |
| Journal: |
Biol Reprod |
| Title: |
Combined iDISCO and CUBIC tissue clearing and lightsheet microscopy for in toto analysis of the adult mouse ovary†. |
| Volume: |
102 |
| Issue: |
5 |
| Pages: |
1080-1089 |
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•
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•
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| Publication |
| First Author: |
Wang X |
| Year: |
2019 |
| Journal: |
Development |
| Title: |
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis. |
| Volume: |
146 |
| Issue: |
13 |
|
|
•
•
•
•
•
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| Genotype |
| Symbol: |
Plekha5/Plekha5<+> Wt1/Wt1 |
| Background: |
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pex5/Pex5 Plekha5/Plekha5<+> |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dicer1/Dicer1 Plekha5/Plekha5<+> |
| Background: |
involves: 129/Sv * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Klf4/Klf4 Plekha5/Plekha5<+> |
| Background: |
involves: C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gja1/Gja1 Plekha5/Plekha5<+> |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Plekha5/Plekha5<+> Tg(Abpa-cre)1Cmal/? |
| Background: |
involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Trim28/Trim28 Plekha5/Plekha5<+> |
| Background: |
involves: 129S2/SvPas * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Rdh10/Rdh10 Tg(Amh-cre)8815Reb/? |
| Background: |
involves: C57BL/6 * C57BL/6N * FVB/N * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tsc22d3/? Plekha5/Plekha5<+> |
| Background: |
involves: 129S1/SvImJ * C57BL/6N * SJL/J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Slc9a8/Slc9a8 Tg(Amh-cre)8815Reb/? |
| Background: |
involves: C57BL/6N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ggcx/Ggcx Tg(AMH-cre)#Sinos/? Tg(AMH-Gja1*)#Sinos/? |
| Background: |
involves: 129S2/SvPas * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cdkn1b/Cdkn1b<+> Plekha5/? Pum1/Pum1 |
| Background: |
involves: 129 * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sox8/Sox8 Sox9/Sox9 Plekha5/Plekha5<+> |
| Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Plekha5/? Sox8/Sox8<+> Sox9/Sox9 |
| Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|