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Search results 1101 to 1200 out of 1225 for Col1a2

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Type Details Score
Publication
First Author: Song MJ
Year: 2023
Journal: Aging Cell
Title: Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction-induced cellular senescence in dermal fibroblasts.
Volume: 22
Issue: 11
Pages: e14000
Publication  
First Author: Werner F
Year: 2023
Journal: JCI Insight
Title: Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice.
Volume: 8
Issue: 13
Publication  
First Author: Chen H
Year: 2016
Journal: Nat Commun
Title: Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.
Volume: 7
Pages: 12564
Publication
First Author: Kapoor M
Year: 2008
Journal: J Clin Invest
Title: GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Volume: 118
Issue: 10
Pages: 3279-90
Genotype
Symbol: Col1a1/Col1a1<+>
Background: involves: C3H/HeJ * C57BL/6J * FVB/NJ
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Liu S
Year: 2010
Journal: J Cell Sci
Title: Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo.
Volume: 123
Issue: Pt 21
Pages: 3674-82
Publication
First Author: Hu B
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.
Volume: 52
Issue: 4
Pages: 418-28
Publication
First Author: Sonnylal S
Year: 2007
Journal: Arthritis Rheum
Title: Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
Volume: 56
Issue: 1
Pages: 334-44
Publication  
First Author: Penke LR
Year: 2022
Journal: JCI Insight
Title: KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis.
Volume: 7
Issue: 16
Publication
First Author: Malaab M
Year: 2022
Journal: Ann Rheum Dis
Title: Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis.
Volume: 81
Issue: 2
Pages: 268-277
Strain
Attribute String: targeted mutation, transgenic, mutant stock
Publication
First Author: Hu B
Year: 2015
Journal: Am J Pathol
Title: Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.
Volume: 185
Issue: 11
Pages: 3066-75
Publication
First Author: Hu B
Year: 2012
Journal: Am J Pathol
Title: Mesenchymal-specific deletion of C/EBPβ suppresses pulmonary fibrosis.
Volume: 180
Issue: 6
Pages: 2257-67
Publication  
First Author: Garrity R
Year: 2023
Journal: Brain Behav Immun
Title: Fibroblast-derived PI16 sustains inflammatory pain via regulation of CD206(+) myeloid cells.
Volume: 112
Pages: 220-234
Publication
First Author: Woodall MC
Year: 2016
Journal: Circ Res
Title: Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion Injury.
Volume: 119
Issue: 10
Pages: 1116-1127
Publication  
First Author: Ruhland MK
Year: 2016
Journal: Nat Commun
Title: Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Volume: 7
Pages: 11762
Publication
First Author: Wermuth PJ
Year: 2018
Journal: PLoS One
Title: Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).
Volume: 13
Issue: 5
Pages: e0196559
Publication
First Author: Shi Y
Year: 2020
Journal: J Pathol
Title: Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Volume: 250
Issue: 1
Pages: 79-94
Publication
First Author: Lagares D
Year: 2017
Journal: Nat Med
Title: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.
Volume: 23
Issue: 12
Pages: 1405-1415
Publication
First Author: Hutchenreuther J
Year: 2015
Journal: J Invest Dermatol
Title: CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis.
Volume: 135
Issue: 11
Pages: 2805-2813
Publication
First Author: Liu S
Year: 2011
Journal: Arthritis Rheum
Title: CCN2 is required for bleomycin-induced skin fibrosis in mice.
Volume: 63
Issue: 1
Pages: 239-46
Publication  
First Author: Eguchi A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: GRK5 is a regulator of fibroblast activation and cardiac fibrosis.
Volume: 118
Issue: 5
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ccn2/Ccn2 Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S2/SvPas * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tgfbr2/Tgfbr2 Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wang W
Year: 2022
Journal: Nat Commun
Title: Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs.
Volume: 13
Issue: 1
Pages: 6358
Publication
First Author: Duan W
Year: 2011
Journal: J Immunol
Title: Inducible CD4+LAP+Foxp3- regulatory T cells suppress allergic inflammation.
Volume: 187
Issue: 12
Pages: 6499-507
Publication  
First Author: Meng X
Year: 2018
Journal: Cancer Lett
Title: Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis.
Volume: 418
Pages: 109-118
Publication
First Author: Parapuram SK
Year: 2011
Journal: J Invest Dermatol
Title: Loss of PTEN expression by dermal fibroblasts causes skin fibrosis.
Volume: 131
Issue: 10
Pages: 1996-2003
Publication
First Author: Liu S
Year: 2009
Journal: Am J Pathol
Title: Rac1 expression by fibroblasts is required for tissue repair in vivo.
Volume: 174
Issue: 5
Pages: 1847-56
Publication
First Author: Huang S
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Res
Title: The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice.
Volume: 1867
Issue: 7
Pages: 118703
Publication
First Author: Liu T
Year: 2015
Journal: PLoS One
Title: Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.
Volume: 10
Issue: 11
Pages: e0142547
Publication
First Author: Beswick EJ
Year: 2014
Journal: J Immunol
Title: TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.
Volume: 193
Issue: 5
Pages: 2218-29
Genotype
Symbol: Tert/Tert Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chen Y
Year: 2022
Journal: Cancer Cell
Title: Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.
Volume: 40
Issue: 8
Pages: 818-834.e9
Publication
First Author: Groenendyk J
Year: 2020
Journal: PLoS One
Title: Selective enhancement of cardiomyocyte efficiency results in a pernicious heart condition.
Volume: 15
Issue: 8
Pages: e0236457
HT Experiment
Series Id: GSE12847
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Nicolas AM
Year: 2022
Journal: Cancer Cell
Title: Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer.
Volume: 40
Issue: 2
Pages: 168-184.e13
Strain
Attribute String: transgenic, targeted mutation, mutant strain
Publication
First Author: Zheng B
Year: 2002
Journal: Am J Pathol
Title: Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis.
Volume: 160
Issue: 5
Pages: 1609-17
Publication
First Author: Kim E
Year: 2020
Journal: Nature
Title: Creation of bladder assembloids mimicking tissue regeneration and cancer.
Volume: 588
Issue: 7839
Pages: 664-669
Publication
First Author: Ijaz T
Year: 2016
Journal: BMC Dev Biol
Title: Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles.
Volume: 16
Issue: 1
Pages: 32
Publication
First Author: Neelisetty S
Year: 2015
Journal: Kidney Int
Title: Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells.
Volume: 88
Issue: 3
Pages: 503-14
Publication
First Author: Zimmermann AS
Year: 2014
Journal: PLoS One
Title: Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.
Volume: 9
Issue: 4
Pages: e93373
Publication
First Author: Wohlfahrt T
Year: 2019
Journal: Nature
Title: PU.1 controls fibroblast polarization and tissue fibrosis.
Volume: 566
Issue: 7744
Pages: 344-349
Publication
First Author: Yamamura Y
Year: 2023
Journal: FASEB J
Title: Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts.
Volume: 37
Issue: 7
Pages: e23005
Publication
First Author: Ubil E
Year: 2014
Journal: Nature
Title: Mesenchymal-endothelial transition contributes to cardiac neovascularization.
Volume: 514
Issue: 7524
Pages: 585-90
Publication
First Author: Bageghni SA
Year: 2018
Journal: FASEB J
Title: Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.
Volume: 32
Issue: 9
Pages: 4941-4954
Publication
First Author: Hamanaka RB
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Volume: 58
Issue: 5
Pages: 585-593
Publication
First Author: Matsumoto Y
Year: 2023
Journal: Sci Rep
Title: Col1α2-Cre-mediated recombination occurs in various cell types due to Cre expression in epiblasts.
Volume: 13
Issue: 1
Pages: 22483
Publication
First Author: Li X
Year: 2019
Journal: FEBS Open Bio
Title: Tamoxifen affects chronic pancreatitis-related fibrogenesis in an experimental mouse model: an effect beyond Cre recombination.
Volume: 9
Issue: 10
Pages: 1756-1768
Publication
First Author: Lim WW
Year: 2020
Journal: PLoS One
Title: Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice.
Volume: 15
Issue: 1
Pages: e0227505
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Col1a2-cre/ERT,-ALPP)7Cpd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Col1a2/Col1a2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Geng X
Year: 2018
Journal: Metallomics
Title: Role of ZIP8 in regulating cell morphology and NF-κB/Snail2 signaling.
Volume: 10
Issue: 7
Pages: 953-964
Publication
First Author: Harris TR
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice.
Volume: 286
Issue: 2
Pages: 102-11
Publication
First Author: Altaf F
Year: 2019
Journal: PLoS One
Title: Modulation of ADAR mRNA expression in patients with congenital heart defects.
Volume: 14
Issue: 4
Pages: e0200968
Publication
First Author: Meng XM
Year: 2012
Journal: Kidney Int
Title: Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.
Volume: 81
Issue: 3
Pages: 266-79
Publication  
First Author: Kim TH
Year: 2019
Journal: Sci Transl Med
Title: Loss of HDAC3 results in nonreceptive endometrium and female infertility.
Volume: 11
Issue: 474
Publication  
First Author: Abdelaziz DM
Year: 2015
Journal: Bone
Title: Behavioral signs of pain and functional impairment in a mouse model of osteogenesis imperfecta.
Volume: 81
Pages: 400-6
Publication
First Author: Arriazu E
Year: 2013
Journal: Lab Invest
Title: GCN2 kinase is a key regulator of fibrogenesis and acute and chronic liver injury induced by carbon tetrachloride in mice.
Volume: 93
Issue: 3
Pages: 303-10
Publication
First Author: Inui Y
Year: 2013
Journal: Biomed Rep
Title: Effects of aging and uninephrectomy on renal changes in Tsukuba hypertensive mice.
Volume: 1
Issue: 3
Pages: 359-364
Publication
First Author: Koda N
Year: 2017
Journal: Development
Title: The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament.
Volume: 144
Issue: 2
Pages: 313-320
Publication
First Author: Campbell BG
Year: 2000
Journal: Arch Biochem Biophys
Title: Sequence of normal canine COL1A1 cDNA and identification of a heterozygous alpha1(I) collagen Gly208Ala mutation in a severe case of canine osteogenesis imperfecta.
Volume: 384
Issue: 1
Pages: 37-46
Publication
First Author: Ghosh AK
Year: 2013
Journal: J Invest Dermatol
Title: p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.
Volume: 133
Issue: 5
Pages: 1302-10
Publication
First Author: Xu Y
Year: 2007
Journal: Mol Immunol
Title: Collagen and major histocompatibility class II expression in mesenchymal cells from CIITA hypomorphic mice.
Volume: 44
Issue: 7
Pages: 1709-21
Publication  
First Author: Fan Y
Year: 2014
Journal: Front Endocrinol (Lausanne)
Title: Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice.
Volume: 5
Pages: 218
Publication
First Author: Bhattacharyya S
Year: 2009
Journal: PLoS One
Title: The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma.
Volume: 4
Issue: 10
Pages: e7620
Publication  
First Author: Eissa N
Year: 2020
Journal: Int J Mol Sci
Title: Interdependence between Chromogranin-A, Alternatively Activated Macrophages, Tight Junction Proteins and the Epithelial Functions. A Human and In-Vivo/In-Vitro Descriptive Study.
Volume: 21
Issue: 21
Publication
First Author: Alfaro MP
Year: 2013
Journal: Lab Invest
Title: A physiological role for connective tissue growth factor in early wound healing.
Volume: 93
Issue: 1
Pages: 81-95
Publication
First Author: Marian AJ
Year: 2006
Journal: J Am Coll Cardiol
Title: Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation.
Volume: 47
Issue: 4
Pages: 827-34
Publication
First Author: Arai KY
Year: 2017
Journal: PLoS One
Title: Postnatal changes and sexual dimorphism in collagen expression in mouse skin.
Volume: 12
Issue: 5
Pages: e0177534
Publication
First Author: Pal D
Year: 2023
Journal: Nat Commun
Title: Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair.
Volume: 14
Issue: 1
Pages: 1129
Publication    
First Author: Kim S
Year: 2019
Journal: Elife
Title: Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer.
Volume: 8
Publication  
First Author: Helfinger V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.
Volume: 118
Issue: 11
Publication
First Author: Cho C
Year: 2020
Journal: Oncogene
Title: Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.
Volume: 39
Issue: 38
Pages: 6129-6137
Publication  
First Author: Bhattacharyya S
Year: 2016
Journal: Nat Commun
Title: Tenascin-C drives persistence of organ fibrosis.
Volume: 7
Pages: 11703
Publication
First Author: Liu S
Year: 2013
Journal: Mol Biol Cell
Title: CCN2 modulates hair follicle cycling in mice.
Volume: 24
Issue: 24
Pages: 3939-44
Publication
First Author: Jackson RS 2nd
Year: 2012
Journal: Neoplasia
Title: Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer.
Volume: 14
Issue: 7
Pages: 656-65
Publication
First Author: Martinez-Ferrer M
Year: 2010
Journal: Am J Pathol
Title: Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure.
Volume: 176
Issue: 1
Pages: 98-107
Publication
First Author: Parapuram SK
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Integrin β1 is necessary for the maintenance of corneal structural integrity.
Volume: 52
Issue: 11
Pages: 7799-806
Publication
First Author: Balaji S
Year: 2017
Journal: FASEB J
Title: Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling.
Volume: 31
Issue: 3
Pages: 868-881
Publication
First Author: Schafer S
Year: 2017
Journal: Nature
Title: IL-11 is a crucial determinant of cardiovascular fibrosis.
Volume: 552
Issue: 7683
Pages: 110-115
Publication
First Author: Pallangyo CK
Year: 2015
Journal: J Exp Med
Title: IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
Volume: 212
Issue: 13
Pages: 2253-66
Publication  
First Author: Currie JD
Year: 2019
Journal: Biol Open
Title: The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts.
Volume: 8
Issue: 7
Publication
First Author: Maity P
Year: 2021
Journal: Cell Rep
Title: Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging.
Volume: 36
Issue: 9
Pages: 109634
Publication
First Author: Guzy RD
Year: 2017
Journal: J Biol Chem
Title: Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling.
Volume: 292
Issue: 25
Pages: 10364-10378
Publication
First Author: Ma ZG
Year: 2023
Journal: Nat Commun
Title: IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice.
Volume: 14
Issue: 1
Pages: 4967
Publication
First Author: Schmidt M
Year: 2016
Journal: J Invest Dermatol
Title: Thy-1/β3 Integrin Interaction-Induced Apoptosis of Dermal Fibroblasts Is Mediated by Up-Regulation of FasL Expression.
Volume: 136
Issue: 2
Pages: 526-529
Publication
First Author: Yokota T
Year: 2020
Journal: Cell
Title: Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
Volume: 182
Issue: 3
Pages: 545-562.e23
Publication
First Author: Pillai ICL
Year: 2017
Journal: Cell Stem Cell
Title: Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification.
Volume: 20
Issue: 2
Pages: 218-232.e5
Publication
First Author: Tsang M
Year: 2020
Journal: Am J Pathol
Title: Insights into Fibroblast Plasticity: Cellular Communication Network 2 Is Required for Activation of Cancer-Associated Fibroblasts in a Murine Model of Melanoma.
Volume: 190
Issue: 1
Pages: 206-221
Publication
First Author: Liu S
Year: 2014
Journal: Arthritis Rheumatol
Title: Skin progenitor cells contribute to bleomycin-induced skin fibrosis.
Volume: 66
Issue: 3
Pages: 707-13
Publication  
First Author: Hutchenreuther J
Year: 2018
Journal: Matrix Biol
Title: Activation of cancer-associated fibroblasts is required for tumor neovascularization in a murine model of melanoma.
Volume: 74
Pages: 52-61
Publication
First Author: Tan J
Year: 2017
Journal: J Immunol
Title: Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12.
Volume: 198
Issue: 6
Pages: 2269-2285
Publication
First Author: Katanasaka Y
Year: 2024
Journal: Nat Commun
Title: Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.
Volume: 15
Issue: 1
Pages: 2472
Publication      
First Author: Kuan CH
Year: 2023
Journal: J Invest Dermatol
Title: Delayed Collagen Production without Myofibroblast Formation Contributes to Reduced Scarring in Adult Skin Microwounds.
Publication
First Author: Wei X
Year: 2019
Journal: Cell Stem Cell
Title: Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.
Volume: 24
Issue: 5
Pages: 753-768.e6
Publication  
First Author: Gao R
Year: 2021
Journal: J Clin Invest
Title: Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.
Volume: 131
Issue: 1
Publication    
First Author: Sun X
Year: 2020
Journal: Elife
Title: Coordinated hedgehog signaling induces new hair follicles in adult skin.
Volume: 9