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Search results 1101 to 1139 out of 1139 for Epha3

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Type

Details

Score

GXD Expression

Probe:	MGI:5699394
Assay Type:	Immunohistochemistry
Annotation Date:	2015-12-18
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1689622
Pattern:	Regionally restricted
Stage:	TS22
Assay Id:	MGI:5699587
Age:	embryonic day 14.5

Note:	Coexpressed with Epha3 in anterior commissure.
Specimen Label:	not shown
Detected:	true
Specimen Num:	8

•

GXD Expression

Probe:	MGI:5699394
Assay Type:	Immunohistochemistry
Annotation Date:	2015-12-18
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1689624
Pattern:	Regionally restricted
Stage:	TS24
Assay Id:	MGI:5699587
Age:	embryonic day 16.5

Note:	Coexpressed with Epha3 in anterior commissure.
Specimen Label:	not shown
Detected:	true
Specimen Num:	9

•

GXD Expression

Probe:	MGI:1340854
Assay Type:	Immunohistochemistry
Annotation Date:	2015-12-18
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3271224
Pattern:	Regionally restricted
Stage:	TS24
Assay Id:	MGI:5699588
Age:	embryonic day 16.5
Image:	11J/K/S
Note:	Coexpressed mainly with Epha3 in the lower region.
Specimen Label:	11J/K/S
Detected:	true
Specimen Num:	3

•

GXD Expression

Probe:	MGI:1340854
Assay Type:	Immunohistochemistry
Annotation Date:	2015-12-18
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3271226
Pattern:	Regionally restricted
Stage:	TS26
Assay Id:	MGI:5699588
Age:	embryonic day 18.5
Image:	11N/O/T
Note:	Coexpressed mainly with Epha3 in the lower region.
Specimen Label:	11N/O/T
Detected:	true
Specimen Num:	4

•

Allele

Epha4<tm7Kln> | MGI:6099091

Name:	Eph receptor A4; targeted mutation 7, Rudiger Klein
Allele Type:	Targeted

•

Allele

Isl2<tm1(Epha3)Grl> | MGI:3056440

Name:	insulin related protein 2 (islet 2); targeted mutation 1, Greg Lemke
Allele Type:	Targeted

•

Publication

15339341 | J:93060

First Author:	Koulakov AA
Year:	2004
Journal:	BMC Neurosci
Title:	A stochastic model for retinocollicular map development.
Volume:	5

Pages:	30

•

Publication

32996883 | J:313509

First Author:	Savier EL
Year:	2020
Journal:	Elife
Title:	New insights on the modeling of the molecular mechanisms underlying neural maps alignment in the midbrain.
Volume:	9

•

Genotype

Symbol:	Isl2/Isl2
Background:	involves: C57BL/6
Zygosity:	hm
Has Mutant Allele:	true

•

Publication

15483613 | J:134532

First Author:	Reber M
Year:	2004
Journal:	Nature
Title:	A relative signalling model for the formation of a topographic neural map.
Volume:	431
Issue:	7010
Pages:	847-53

•

Publication

14614096 | J:97411

First Author:	Honda H
Year:	2003
Journal:	J Neurosci
Title:	Competition between retinal ganglion axons for targets under the servomechanism model explains abnormal retinocollicular projection of Eph receptor-overexpressing or ephrin-lacking mice.
Volume:	23
Issue:	32
Pages:	10368-77

•

Publication

16941478 | -

First Author:	Wood LD
Year:	2006
Journal:	Hum Mutat
Title:	Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
Volume:	27
Issue:	10
Pages:	1060-1

•

Protein Domain

IPR034266 | EphA3_rcpt_lig-bd

Type:

Domain

Description:

This entry represents the ligand-binding domain found in ephrin type-A receptor 3 (EphA3). EphA3 has also been implicated in lung tumors []. Class EphA receptors bind GPI-anchored ephrin-A ligands. There are ten vertebrate EphA receptors (EphA1-10), which display promiscuous interactions with six ephrin-A ligands [, ]. Ephrin receptors (EphRs) comprise the largest subfamily of receptor tyrosine kinases (RTKs). EphRs contain a ligand binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic tyrosine kinase domain. Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting downstream signals occur bidirectionally in both EphR-expressing cells (forward signaling) and ephrin-expressing cells (reverse signaling) [].

•

Publication

21753007 | J:174517

First Author:	Bevins N
Year:	2011
Journal:	J Neurosci
Title:	Genetic dissection of EphA receptor signaling dynamics during retinotopic mapping.
Volume:	31
Issue:	28
Pages:	10302-10

•

Publication

19804762 | J:157312

First Author:	Triplett JW
Year:	2009
Journal:	Cell
Title:	Retinal input instructs alignment of visual topographic maps.
Volume:	139
Issue:	1
Pages:	175-85

•

Publication

26402608 | J:227657

First Author:	Owens MT
Year:	2015
Journal:	Neuron
Title:	Stochastic Interaction between Neural Activity and Molecular Cues in the Formation of Topographic Maps.
Volume:	87
Issue:	6
Pages:	1261-73

•

Publication

29066954 | J:284758

First Author:	Kay RB
Year:	2017
Journal:	Front Neural Circuits
Title:	Visual Neurons in the Superior Colliculus Innervated by Islet2⁺ or Islet2^- Retinal Ganglion Cells Display Distinct Tuning Properties.
Volume:	11

Pages:	73

•

Publication

19823572 | J:154609

First Author:	Janes PW
Year:	2009
Journal:	PLoS Biol
Title:	Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10.
Volume:	7
Issue:	10
Pages:	e1000215

•

Publication

31831727 | J:286720

First Author:	Volta F
Year:	2019
Journal:	Nat Commun
Title:	Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
Volume:	10
Issue:	1
Pages:	5686

•

Publication

22144690 | J:178920

First Author:	Janes PW
Year:	2011
Journal:	J Cell Biol
Title:	Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors.
Volume:	195
Issue:	6
Pages:	1033-45

•

Publication

22496572 | J:184449

First Author:	Triplett JW
Year:	2012
Journal:	J Neurosci
Title:	Alignment of multimodal sensory input in the superior colliculus through a gradient-matching mechanism.
Volume:	32
Issue:	15
Pages:	5264-71

•

Publication

24495295 | J:207469

First Author:	Triplett JW
Year:	2014
Journal:	Neural Dev
Title:	Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits.
Volume:	9

Pages:	2

•

Publication

11870224 | J:175107

First Author:	Lawrenson ID
Year:	2002
Journal:	J Cell Sci
Title:	Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.
Volume:	115
Issue:	Pt 5
Pages:	1059-72

•

Publication

25123133 | J:216179

First Author:	Chiappalupi S
Year:	2014
Journal:	Carcinogenesis
Title:	Defective RAGE activity in embryonal rhabdomyosarcoma cells results in high PAX7 levels that sustain migration and invasiveness.
Volume:	35
Issue:	10
Pages:	2382-92

•

Publication

16690216 | J:110251

First Author:	Otal R
Year:	2006
Journal:	Neuroscience
Title:	Ephrin-A5 modulates the topographic mapping and connectivity of commissural axons in murine hippocampus.
Volume:	141
Issue:	1
Pages:	109-21

•

Publication

25281279 | J:216970

First Author:	Wurzman R
Year:	2015
Journal:	Behav Brain Res
Title:	Repetitive grooming and sensorimotor abnormalities in an ephrin-A knockout model for Autism Spectrum Disorders.
Volume:	278

Pages:	115-28

•

Publication

15014130 | J:90078

First Author:	Feldheim DA
Year:	2004
Journal:	J Neurosci
Title:	Loss-of-function analysis of EphA receptors in retinotectal mapping.
Volume:	24
Issue:	10
Pages:	2542-50

•

Publication

- | J:239807

First Author:	Gagnon LH
Year:	2017
Journal:	MGI Direct Data Submission
Title:	The spontaneous dominant mutation elliptic (Ept)

•

Publication

28732181 | J:255609

First Author:	Kousa YA
Year:	2017
Journal:	J Dent Res
Title:	IRF6 and SPRY4 Signaling Interact in Periderm Development.
Volume:	96
Issue:	11
Pages:	1306-1313

•

Publication

29670169 | J:263162

First Author:	Sullivan CS
Year:	2018
Journal:	Sci Rep
Title:	Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons.
Volume:	8
Issue:	1
Pages:	6143

•

Publication

20960543 | J:166527

First Author:	Frieden LA
Year:	2010
Journal:	Dev Dyn
Title:	Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1.
Volume:	239
Issue:	12
Pages:	3226-34

•

Publication

25264256 | J:247837

First Author:	Gatto G
Year:	2014
Journal:	Curr Biol
Title:	EphA4 receptor shedding regulates spinal motor axon guidance.
Volume:	24
Issue:	20
Pages:	2355-65

•

Publication

18413883 | -

First Author:	Lackmann M
Year:	2008
Journal:	Sci Signal
Title:	Eph, a protein family coming of age: more confusion, insight, or complexity?
Volume:	1
Issue:	15
Pages:	re2

•

Protein

Q8C9K6

Organism:	Mus musculus/domesticus
Length:	538
Fragment?:	false

•

Publication

12495863 | -

First Author:	Himanen JP
Year:	2003
Journal:	Trends Neurosci
Title:	Eph signaling: a structural view.
Volume:	26
Issue:	1
Pages:	46-51

•

Protein

P29319

Organism:	Mus musculus/domesticus
Length:	983
Fragment?:	false

•

Protein

B7ZNN5

Organism:	Mus musculus/domesticus
Length:	983
Fragment?:	false

•

Protein

Q8BRB1

Organism:	Mus musculus/domesticus
Length:	984
Fragment?:	false

•

Protein

Q8C3U1

Organism:	Mus musculus/domesticus
Length:	984
Fragment?:	false

•

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