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Search results 1101 to 1200 out of 2260 for Erbb2

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Hits by Strain

Type Details Score
Allele
Erbin<tm1Line> | MGI:3849990
Name: Erbb2 interacting protein; targeted mutation 1, Lin Mei
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:4839785 | B6;129P2-Erbin<Gt(BGA258)Byg>/Mmucd
Attribute String: mutant stock, gene trap
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Allele
Erbin<em1Gpt> | MGI:7298631
Name: Erbb2 interacting protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Erbin<em2Gpt> | MGI:7298632
Name: Erbb2 interacting protein; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Erbin<em2Cya> | MGI:7793265
Name: Erbb2 interacting protein; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Erbin/Erbin
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
17259656 | J:122084
First Author: Ip MM
Year: 2007
Journal: Carcinogenesis
Title: The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium.
Volume: 28
Issue: 6
Pages: 1269-76
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Publication
24309211 | J:258490
First Author: Schulz A
Year: 2014
Journal: Brain
Title: Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling.
Volume: 137
Issue: Pt 2
Pages: 420-32
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Publication
17705881 | J:138100
First Author: Calogero RA
Year: 2007
Journal: Breast Cancer Res
Title: Inflammation and breast cancer. Inflammatory component of mammary carcinogenesis in ErbB2 transgenic mice.
Volume: 9
Issue: 4
Pages: 211
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Pathway
R-MMU-1963640 | GRB2 events in ERBB2 signaling
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Pathway
R-MMU-9652282 | Drug-mediated inhibition of ERBB2 signaling
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Pathway
R-MMU-1250196 | SHC1 events in ERBB2 signaling
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Pathway
R-MMU-1306955 | GRB7 events in ERBB2 signaling
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Pathway
R-MMU-1963642 | PI3K events in ERBB2 signaling
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Interaction Experiment
Jansen SM (2009)
Description: ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site.
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Publication
18614673 | J:138014
First Author: Arikkath J
Year: 2008
Journal: J Neurosci
Title: Erbin controls dendritic morphogenesis by regulating localization of delta-catenin.
Volume: 28
Issue: 28
Pages: 7047-56
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Allele
Erbin<Gt(Ayu21-W487)Imeg> | MGI:4833563
 
Name: Erbb2 interacting protein; gene trap Ayu21-W487, Institute of Molecular Embryology and Genetics
Allele Type: Gene trapped
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Strain
MGI:6351676 | C57BL/6JGpt-Erbin<em2Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7838314 | C57BL/6N-Erbin<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Erbin/Erbin
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
21044682 | -
First Author: Meijer IM
Year: 2011
Journal: Cell Signal
Title: ERBB2 is a target for USP8-mediated deubiquitination.
Volume: 23
Issue: 2
Pages: 458-67
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Protein
Q91VH6
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Publication
20435927 | J:161226
First Author: Rolla S
Year: 2010
Journal: J Immunol
Title: Erbb2 DNA vaccine combined with regulatory T cell deletion enhances antibody response and reveals latent low-avidity T cells: potential and limits of its therapeutic efficacy.
Volume: 184
Issue: 11
Pages: 6124-32
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Publication
20197467 | J:157981
First Author: Efferson CL
Year: 2010
Journal: Cancer Res
Title: Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
Volume: 70
Issue: 6
Pages: 2476-84
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Protein Coding Gene
MGI:1917818 | Cpne3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109559 | Ptprr
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20937854 | -
First Author: Zaoui K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.
Volume: 107
Issue: 43
Pages: 18517-22
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Publication
18719096 | -
First Author: Xiang B
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Brk is coamplified with ErbB2 to promote proliferation in breast cancer.
Volume: 105
Issue: 34
Pages: 12463-8
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Publication
19263517 | -
First Author: Jansen SM
Year: 2009
Journal: Cell Signal
Title: ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site.
Volume: 21
Issue: 5
Pages: 810-8
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Protein Coding Gene
MGI:108410 | Ptpn18
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99259 | Matk
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1924140 | Memo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P41242
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Protein
Q61152
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Publication
26056141 | J:227321
First Author: Xie CM
Year: 2015
Journal: J Cell Biol
Title: Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Volume: 209
Issue: 5
Pages: 721-37
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Publication
18724389 | -
First Author: Chen C
Year: 2008
Journal: Oncogene
Title: The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
Volume: 27
Issue: 54
Pages: 6845-55
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Protein Coding Gene
MGI:96070 | Hbegf
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16203728 | J:221560
First Author: McDonald C
Year: 2005
Journal: J Biol Chem
Title: A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling.
Volume: 280
Issue: 48
Pages: 40301-9
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Publication
12650946 | J:230356
First Author: Warner DR
Year: 2003
Journal: FEBS Lett
Title: Identification of three novel Smad binding proteins involved in cell polarity.
Volume: 539
Issue: 1-3
Pages: 167-73
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Publication
16407820 | -
First Author: Tan M
Year: 2006
Journal: Oncogene
Title: Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors.
Volume: 25
Issue: 23
Pages: 3286-95
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GO Term
GO:0038143 | ERBB3:ERBB2 complex
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GO Term
GO:0038144 | ERBB4:ERBB2 complex
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Protein Coding Gene
MGI:104673 | Ptpn12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P35831
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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GO Term
GO:0038133 | ERBB2-ERBB3 signaling pathway
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Allele
Tg(Erbb2)1Jek | MGI:1891491
Name: transgene insertion 1, Jeffrey E Kudlow
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Publication
18045866 | J:131332
First Author: Qiu C
Year: 2008
Journal: J Biol Chem
Title: Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site.
Volume: 283
Issue: 5
Pages: 2734-40
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Protein Coding Gene
MGI:1098246 | Nrg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95411 | Erbb3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22912742 | J:189979
First Author: Sysa-Shah P
Year: 2012
Journal: PLoS One
Title: Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice.
Volume: 7
Issue: 8
Pages: e42805
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Protein Coding Gene
MGI:1914838 | Rnf41
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8BH75
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Allele
Erbb2<tm1Cbm> | MGI:1929071
Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 1, Carmen Birchmeier
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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GO Term
GO:0038135 | ERBB2-ERBB4 signaling pathway
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GO Term
GO:0038134 | ERBB2-EGFR signaling pathway
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GO Term
GO:0038142 | EGFR:ERBB2 complex
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Publication
27619642 | J:242097
 
First Author: Lee H
Year: 2016
Journal: Nat Commun
Title: Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.
Volume: 7
Pages: 12799
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Publication
19690134 | J:152158
First Author: Ranger JJ
Year: 2009
Journal: Cancer Res
Title: Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression.
Volume: 69
Issue: 17
Pages: 6823-30
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Publication
16061875 | J:100183
First Author: Kiguchi K
Year: 2005
Journal: Clin Cancer Res
Title: Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma.
Volume: 11
Issue: 15
Pages: 5572-80
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Allele
Tg(MMTV-Erbb2)17Pjo | MGI:3039531
Name: transgene insertion 17, Paul Jolicoeur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Erbb2)10Pjo | MGI:3039039
Name: transgene insertion 10, Paul Jolicoeur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Erbb2)9Pjo | MGI:3047079
Name: transgene insertion 9, Paul Jolicoeur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Erbb2)12Pjo | MGI:3047089
Name: transgene insertion 12, Paul Jolicoeur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Erbb2<tm8(Erbb2)Mul> | MGI:3525444
Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 8, William J Muller
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Tg(MMTV-Erbb2*,-cre)1Mul | MGI:4361017
Name: transgene insertion 1, William J Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Recombinase
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Allele
Tg(MMTV-ERBB2*,-luc)6177Aami | MGI:5013906
Name: transgene insertion 6177, Augusto Amici
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-ERBB2*,-luc)6180Aami | MGI:5013907
Name: transgene insertion 6180, Augusto Amici
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-ERBB2*,-luc)6157Aami | MGI:5013830
Name: transgene insertion 6157, Augusto Amici
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Tg(Myh6-Erbb2)6Kaga | MGI:5461578
Name: transgene insertion 6, Kathleen Gabrielson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(tetO-ERBB2)#Jjz | MGI:5775596
Name: transgene insertion, Jean J Zhao
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<em1(CAG-ERBB2*V777L)Bose> | MGI:7524181
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Ron Bose
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Erbb2)1Jek/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Publication
17460049 | J:121297
First Author: Ju X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Akt1 governs breast cancer progression in vivo.
Volume: 104
Issue: 18
Pages: 7438-43
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Publication
24382758 | J:213023
First Author: Lakritz JR
Year: 2014
Journal: Int J Cancer
Title: Beneficial bacteria stimulate host immune cells to counteract dietary and genetic predisposition to mammary cancer in mice.
Volume: 135
Issue: 3
Pages: 529-40
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Publication
25853295 | J:345620
First Author: Castellanos-Martín A
Year: 2015
Journal: Genome Biol
Title: Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach.
Volume: 16
Issue: 1
Pages: 40
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Publication
23451056 | J:198481
First Author: Andrade-Vieira R
Year: 2013
Journal: PLoS One
Title: Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways.
Volume: 8
Issue: 2
Pages: e56567
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Protein Coding Gene
MGI:96083 | Nrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99439 | Btc
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102683 | Grb7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97599 | Prkce
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1194490 | Diaph1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1934029 | Usp8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109531 | Cdc37
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1922967 | Cul5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80TH2
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
O08808
Organism: Mus musculus/domesticus
Length: 1255  
Fragment?: false
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Protein
Q03160
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
Q9D5V5
Organism: Mus musculus/domesticus
Length: 780  
Fragment?: false
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Protein
Q61081
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Protein
Q80U87
Organism: Mus musculus/domesticus
Length: 1080  
Fragment?: false
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Protein
P16054
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: false
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Protein Coding Gene
MGI:107508 | Ereg
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30611309 | J:298753
First Author: Floris A
Year: 2019
Journal: J Exp Clin Cancer Res
Title: Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.
Volume: 38
Issue: 1
Pages: 4
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Publication
18339686 | J:138507
First Author: Meng X
Year: 2008
Journal: Carcinogenesis
Title: t10,c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways.
Volume: 29
Issue: 5
Pages: 1013-21
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Publication
24280377 | J:349082
First Author: Dupuy F
Year: 2013
Journal: Cancer Metab
Title: LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer.
Volume: 1
Issue: 1
Pages: 18
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Publication
19141783 | J:144996
First Author: Strecker TE
Year: 2009
Journal: J Natl Cancer Inst
Title: Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice.
Volume: 101
Issue: 2
Pages: 107-13
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Publication
27998284 | J:309346
First Author: Wellberg EA
Year: 2016
Journal: Breast Cancer Res
Title: The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.
Volume: 18
Issue: 1
Pages: 131
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Publication
24763051 | J:320320
 
First Author: Li D
Year: 2014
Journal: Cell Death Dis
Title: A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress.
Volume: 5
Pages: e1194
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Publication
17259984 | J:120342
First Author: Julien SG
Year: 2007
Journal: Nat Genet
Title: Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis.
Volume: 39
Issue: 3
Pages: 338-46
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Publication
20810647 | J:163521
First Author: Bai L
Year: 2010
Journal: Genes Dev
Title: s-SHIP promoter expression marks activated stem cells in developing mouse mammary tissue.
Volume: 24
Issue: 17
Pages: 1882-92
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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