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Search results 1101 to 1200 out of 3232 for Erg

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:2667600
Age: embryonic day 8.5
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2667600
Age: embryonic day 9.5
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2667600
Age: embryonic day 10.5
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:2667600
Age: embryonic day 13.0
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:2667600
Age: embryonic day 15.0
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:2667430
Assay Type: RNA in situ
Annotation Date: 2003-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:2667600
Age: embryonic day 17.0
Note: The authors state that expression paralleled that of the Erg gene in endothelial and mesodermal tissues (see assay MGI:2667555).
Specimen Label: Not Shown
Detected: true
Specimen Num: 8
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Allele
Cep290<rd16> | MGI:3624136
Name: centrosomal protein 290; retinal degeneration 16
Allele Type: Spontaneous
Attribute String: Hypomorph
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Allele
Cep290<tm2.1Rwjc> | MGI:5578357
Name: centrosomal protein 290; targeted mutation 2.1, Robert WJ Collin
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
18687716 | J:152828
First Author: Maddox DM
Year: 2008
Journal: J Physiol
Title: Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses.
Volume: 586
Issue: 18
Pages: 4409-24
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Heritable Phenotypic Marker
MGI:3580285 | biga1
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Heritable Phenotypic Marker
MGI:4867509 | cpfl6
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
- | J:167198
First Author: Chang B
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: A New Mouse Model of Cone Photoreceptor Function Loss (cpfl6) Associated With the Targeted Hcn1 Gene Mutation
Volume: 47
Issue: 13
Pages: 2294
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Protein
O35219-2
Organism: Mus musculus/domesticus
Length: 1103  
Fragment?: false
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Protein
O35219-3
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Gene
4308 | TRPM1
Type: gene
Organism: human
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Protein
Q9ER47
Organism: Mus musculus/domesticus
Length: 1195  
Fragment?: false
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Protein
A0A0R4J1K0
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Publication
17430614 | J:130596
First Author: Pinto LH
Year: 2007
Journal: Vis Neurosci
Title: Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.
Volume: 24
Issue: 1
Pages: 111-23
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Publication
- | J:167199
First Author: Hawes NL
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: A New Mouse Model of Cone Photoreceptor Fuction Loss (cpfl7)
Volume: 48
Issue: 13
Pages: 1350
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Publication
15974803 | J:100116
First Author: Codrington R
Year: 2005
Journal: PLoS Biol
Title: The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells.
Volume: 3
Issue: 8
Pages: e242
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Protein
M0QW64
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
Q32ME0
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: false
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Allele
Ewsr1<tm1(ERG)Thr> | MGI:3584017
Name: Ewing sarcoma breakpoint region 1; targeted mutation 1, Terence H Rabbitts
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key> | MGI:5524275
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Charles L Sawyers
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Publication
15782166 | J:98679
First Author: Forster A
Year: 2005
Journal: Nat Methods
Title: The invertor knock-in conditional chromosomal translocation mimic.
Volume: 2
Issue: 1
Pages: 27-30
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Genotype
Genotype
Symbol: Cep290/Cep290
Background: involves: BXD24/TyJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cep290/Cep290 Nrl/Nrl
Background: involves: 129S1/Sv * 129X1/SvJ * BXD24/TyJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cep290/Cep290
Background: involves: BXD24/TyJ
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110291 | Leber congenital amaurosis 10
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DO Term
DOID:0050534 | congenital stationary night blindness
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Gene
778 | CACNA1F
Type: gene
Organism: human
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Protein
Q80XE8
Organism: Mus musculus/domesticus
Length: 1117  
Fragment?: true
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Protein
Q53Z09
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
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MP Term
MP:0012040 | abnormal c-wave shape
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MP Term
MP:0020974 | abnormal FO-wave shape
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Publication
19625520 | J:151796
First Author: Cao Y
Year: 2009
Journal: J Neurosci
Title: Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.
Volume: 29
Issue: 29
Pages: 9301-13
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Publication
18001285 | J:130134
First Author: Morgans CW
Year: 2007
Journal: Eur J Neurosci
Title: Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells.
Volume: 26
Issue: 10
Pages: 2899-905
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Publication
20847113 | J:171559
First Author: Thompson S
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Different inner retinal pathways mediate rod-cone input in irradiance detection for the pupillary light reflex and regulation of behavioral state in mice.
Volume: 52
Issue: 1
Pages: 618-23
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HT Experiment
E-GEOD-46481 | Expression data from transgenic ERG, GATA1s KI and ERG/GATA1s fetal livers
Series Id: GSE46481
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Heritable Phenotypic Marker
MGI:3696947 | cpfl7
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Strain
MGI:5615640 | B6.129-Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tmprss2<tm1.1(ERG)Sho> | MGI:5578606
Name: transmembrane protease, serine 2; targeted mutation 1.1, Stuart Orkin
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: Tg(Vav1-ERG)#Jpim/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Publication
28439080 | J:275034
First Author: Sreenath TL
Year: 2017
Journal: Sci Rep
Title: ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development.
Volume: 7
Issue: 1
Pages: 1109
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Strain
MGI:3622784 | C57BL/6J-Grm6<nob4>/Nwu
Attribute String: coisogenic, chemically induced mutation, mutant strain
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Strain
MGI:3580431 | C57BL/6J-Grm6<nob4>
Attribute String: coisogenic, mutant strain, chemically induced mutation
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Genotype
Genotype
Symbol: Grm6/Grm6
Background: C57BL/6J-Grm6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grm6/Grm6
Background: involves: C57BL/6J * C57BL/10 * DBA/2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grm6/Grm6
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
25780911 | J:232913
First Author: Linn DE
Year: 2015
Journal: PLoS One
Title: Genetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse models.
Volume: 10
Issue: 3
Pages: e0120628
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Protein Coding Gene
MGI:2384917 | Cep290
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Nrl<tm1Asw> | MGI:2152376
Name: neural retina leucine zipper gene; targeted mutation 1, Anand Swaroop
Allele Type: Targeted
Attribute String: Null/knockout
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Gene
162514 | TRPV3
Type: gene
Organism: human
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Gene
3000 | GUCY2D
Type: gene
Organism: human
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Gene
80184 | CEP290
Type: gene
Organism: human
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HT Experiment
GSE184624 | TMPRSS2-ERG and gain-of-function p53 mutants co-dictate pyrimidine synthesis and prostate cancer fitness [RNA-seq-2018 ERG-p53 project]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE184625 | TMPRSS2-ERG and gain-of-function p53 mutants co-dictate pyrimidine synthesis and prostate cancer fitness [RNA-seq-2021 ERG-p53 project]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE264257 | The prion protein is required for normal responses to light stimuli by photoreceptor and bipolar cells
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Genotype
Genotype
Symbol: C5ar1/C5ar1
Background: B6.129S4(Cg)-C5ar1
Zygosity: hm
Has Mutant Allele: true
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Publication
10798390 | -
First Author: Littleton JT
Year: 2000
Journal: Neuron
Title: Ion channels and synaptic organization: analysis of the Drosophila genome.
Volume: 26
Issue: 1
Pages: 35-43
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Publication
16554806 | -
First Author: Sanguinetti MC
Year: 2006
Journal: Nature
Title: hERG potassium channels and cardiac arrhythmia.
Volume: 440
Issue: 7083
Pages: 463-9
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Publication
19027781 | -
First Author: Perrin MJ
Year: 2008
Journal: Prog Biophys Mol Biol
Title: Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.
Volume: 98
Issue: 2-3
Pages: 137-48
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Publication
22742967 | -
First Author: Jonsson MK
Year: 2012
Journal: J Mol Cell Cardiol
Title: Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.
Volume: 53
Issue: 3
Pages: 369-74
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Protein Domain
IPR030172 | KCNH6
Type: Family
Description: Potassium voltage-gated channel subfamily H member 6 (KCNH6), also known as ether-a-go-go-related gene (ERG, ERG2), has a key role in the control of cardiac action potential repolarisation [, ]. It is a pore-forming (alpha) subunit of voltage-gated potassium channel. In human, mutations in ERG can cause congenital long QT syndrome, a disorder of cardiac repolarisation [].
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Allele
Tg(Pbsn-ERG*)1Vv | MGI:4358243
Name: transgene insertion 1, Valeri Vasioukhin
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Ewsr1/Ewsr1<+> Rag1/Rag1<+>
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten<+> Tmprss2/Tmprss2
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tmprss2/Tmprss2
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Publication
21052544 | J:166679
 
First Author: Won J
Year: 2011
Journal: J Ophthalmol
Title: Mouse model resources for vision research.
Volume: 2011
Pages: 391384
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Publication
31277777 | J:309459
First Author: Shinde D
Year: 2019
Journal: Eur Urol Oncol
Title: Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.
Volume: 2
Issue: 4
Pages: 415-424
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Publication
30078722 | J:265865
First Author: Sandoval GJ
Year: 2018
Journal: Mol Cell
Title: Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Volume: 71
Issue: 4
Pages: 554-566.e7
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Publication
33197500 | J:299962
 
First Author: Lagali PS
Year: 2021
Journal: Neuroscience
Title: Sensory Experience Modulates Atrx-mediated Neuronal Integrity in the Mouse Retina.
Volume: 452
Pages: 169-180
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Strain
MGI:4359795 | STOCK Tg(Pbsn-ERG*)1Vv/J
Attribute String: transgenic, mutant stock
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Genotype
Genotype
Symbol: Tg(Pbsn-ERG*)1Vv/?
Background: involves: 129/Sv * C57BL/6J * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pbsn-ERG*)1Vv/?
Background: involves: 129S1/SvImJ * C57BL/6J * CBA
Zygosity: ot
Has Mutant Allele: true
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Publication
18214746 | J:130158
First Author: Koyasu T
Year: 2008
Journal: Curr Eye Res
Title: Photopic electroretinograms of mGluR6-deficient mice.
Volume: 33
Issue: 1
Pages: 91-9
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Allele
Adamtsl4<tvrm267> | MGI:5902816
Name: ADAMTS-like 4; translational vision research model 267
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Ctnna1/Ctnna1<+>
Background: C57BL/6J-Ctnna1/Pjn
Zygosity: ht
Has Mutant Allele: true
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Publication
28986382 | J:252314
First Author: Yang Y
Year: 2017
Journal: Cancer Res
Title: Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion.
Volume: 77
Issue: 23
Pages: 6524-6537
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Publication
26241901 | J:229885
 
First Author: Qian H
Year: 2015
Journal: Vis Neurosci
Title: Identification of a new mutant allele, Grm6(nob7), for complete congenital stationary night blindness.
Volume: 32
Pages: E004
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Publication
- | J:351808
     
First Author: Chang B
Year: 2024
Journal: MGI Direct Data Submission
Title: The Grm6 mutation.
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Publication
- | J:351807
     
First Author: Chang B
Year: 2024
Journal: MGI Direct Data Submission
Title: The Grm6 mutation.
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Publication
29844131 | J:286345
First Author: Blee AM
Year: 2018
Journal: Clin Cancer Res
Title: TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer.
Volume: 24
Issue: 18
Pages: 4551-4565
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Publication
30924851 | J:274764
First Author: Wu KC
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Deletion of miR-182 Leads to Retinal Dysfunction in Mice.
Volume: 60
Issue: 4
Pages: 1265-1274
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Publication
17065522 | J:122428
First Author: Chang B
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Cone photoreceptor function loss-3, a novel mouse model of achromatopsia due to a mutation in Gnat2.
Volume: 47
Issue: 11
Pages: 5017-21
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Publication
29518352 | J:260407
 
First Author: Ronning KE
Year: 2018
Journal: Exp Eye Res
Title: Loss of cone function without degeneration in a novel Gnat2 knock-out mouse.
Volume: 171
Pages: 111-118
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Genotype
Genotype
Symbol: Adamtsl4/Adamtsl4
Background: C57BL/6J-Adamtsl4/Pjn
Zygosity: hm
Has Mutant Allele: true
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Publication
28559309 | J:244554
First Author: Xiang L
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: miR-183/96 plays a pivotal regulatory role in mouse photoreceptor maturation and maintenance.
Volume: 114
Issue: 24
Pages: 6376-6381
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Publication
32025181 | J:291964
 
First Author: Kinoshita J
Year: 2019
Journal: Mol Vis
Title: Reduced expression of the nob8 gene does not normalize the distribution or function of mGluR6 in the mouse retina.
Volume: 25
Pages: 890-901
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Publication
26990161 | J:257589
First Author: Kominami T
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Temporal Properties of Cone ERGs of Pikachurin Null Mutant Mouse.
Volume: 57
Issue: 3
Pages: 1264-9
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Publication
24084093 | J:214877
First Author: Klooster J
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.
Volume: 54
Issue: 10
Pages: 6973-81
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Publication
10191308 | J:54018
First Author: Trudeau MC
Year: 1999
Journal: J Neurosci
Title: Functional analysis of a mouse brain Elk-type K+ channel.
Volume: 19
Issue: 8
Pages: 2906-18
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Publication
17408617 | J:126462
First Author: Nusinowitz S
Year: 2007
Journal: Exp Eye Res
Title: Temporal response properties of the primary and secondary rod-signaling pathways in normal and Gnat2 mutant mice.
Volume: 84
Issue: 6
Pages: 1104-14
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Publication
25416620 | J:232613
First Author: Ramakrishnan H
Year: 2015
Journal: J Physiol
Title: Differential function of Gγ13 in rod bipolar and ON cone bipolar cells.
Volume: 593
Issue: 7
Pages: 1531-50
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HT Experiment
GSE163693 | The developing mouse coronal suture at single-cell resolution
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
28490646 | J:240996
First Author: Peachey NS
Year: 2017
Journal: J Neurophysiol
Title: A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function.
Volume: 118
Issue: 2
Pages: 845-854
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Publication
33986362 | J:318049
First Author: Gao S
Year: 2021
Journal: Sci Rep
Title: Functional regulation of an outer retina hyporeflective band on optical coherence tomography images.
Volume: 11
Issue: 1
Pages: 10260
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ncRNA Gene
MGI:2676847 | Mir183
Type: miRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CAROLIEiJ_G0008013 | -
Type: ncRNA_gene
Organism: Mus caroli
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ncRNA Gene
MGP_129S1SvImJ_G0008890 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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