|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1101 to 1200 out of 1262 for Ezh2

<< First    < Previous  |  Next >    Last >>
0.044s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
25064842 | -
First Author: Lu H
Year: 2014
Journal: FEBS Lett
Title: New tumor suppressor CXXC finger protein 4 inactivates mitogen activated protein kinase signaling.
Volume: 588
Issue: 18
Pages: 3322-6
•
•
•
•
•
Protein Domain
IPR040388 | CXXC4/CXXC5
Type: Family
Description: This entry represents CXXC-type zinc finger proteins CXXC4 and CXXC5. CXXC4 is a potential tumour suppressor directly regulated by EZH2 []. It has been shown to inactivate mitogen activated protein kinase signaling []. CXXC5 is a retinoid-inducible nuclear factor (RINF) involved in normal myelopoiesis []. It has been associated with various malignant tumours [].
•
•
•
•
•
Protein Domain
IPR040595 | EZH2_N
Type: Domain
Description: Polycomb repressive complex 2 (PRC2) carries out the methylation of lysine 27 of histone H3, a hallmark of repressive chromatin. Three core subunits make up the catalytic core of PRC2; the SET domain containing EZH2, the zinc-finger containing SUZ12 and the WD40 repeat protein EED. The complex forms a compact arrangement of three lobes. This is the N-terminal domain of EZH2 [].
•
•
•
•
•
Publication
23970558 | J:201058
First Author: Nguyen KD
Year: 2013
Journal: Science
Title: Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.
Volume: 341
Issue: 6153
Pages: 1483-8
•
•
•
•
•
Allele
Ezh2<tm1.1Nesh> | MGI:6393578
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1.1, Norman E Sharpless
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
•
•
•
•
•
Publication
33004350 | J:299185
First Author: Koss B
Year: 2020
Journal: Cancer Res
Title: Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.
Volume: 80
Issue: 21
Pages: 4707-4719
•
•
•
•
•
Allele
H3f3a<tm1Hjf> | MGI:7509717
Name: H3.3 histone A; targeted mutation 1, Hans Joerg Fehling
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Reporter
•
•
•
•
•
HT Experiment
GSE57391 | RNA-seq profiling of gene expression in Ezh2-deficient and control murine lung epithelial and stromal cell populations at day E16.5
Series Id: E-GEOD-57391
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
HT Experiment
GSE14045 | Analysis of changes in gene expression in epidermal stem cells upon loss of Polycomb silencing
Series Id: E-GEOD-14045
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
HT Experiment
E-GEOD-34274 | Gene expression profile of right ventricles from adult wild type and Ezh2-deficient hearts
Series Id: GSE34274
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
27122193 | -
 
First Author: Brooun A
Year: 2016
Journal: Nat Commun
Title: Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.
Volume: 7
Pages: 11384
•
•
•
•
•
Protein Domain
IPR040968 | Ezh2_MCSS
Type: Domain
Description: Polycomb repressive complex 2 (PRC2) carries out the methylation of lysine 27 of histone H3, a hallmark of repressive chromatin. Three core subunits make up the catalytic core of PRC2; the SET domain containing EZH2, the zinc-finger containing SUZ12 and the WD40 repeat protein EED. The complex forms a compact arrangement of three lobes. The middle lobe largely comprises two domains that mark the beginning of the carboxy (C)-terminal region of EZH2 (MCSS and SANT2) and the helical, C-terminal, component of the Suz12 Vefs domain. This entry describes the MCSS (also known as SANT2L) domain. There is one zinc binding (Zn1Cys3His1) which is formed solely by MCSS [, ].
•
•
•
•
•
Publication
27121947 | -
 
First Author: Justin N
Year: 2016
Journal: Nat Commun
Title: Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Volume: 7
Pages: 11316
•
•
•
•
•
Strain
MGI:7509719 | B6.129-H3f3a<tm1Hjf>/J
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Ezh2/Ezh2<+> Cd19/Cd19<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ezh2/Ezh2 Cd19/Cd19<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cd19/Cd19<+> Ezh2/Ezh2<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein
P70351
Organism: Mus musculus/domesticus
Length: 747  
Fragment?: false
•
•
•
•
•
Protein
A0A0R4J1C0
Organism: Mus musculus/domesticus
Length: 750  
Fragment?: false
•
•
•
•
•
HT Experiment
E-GEOD-50951 | EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia
Series Id: GSE50951
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Genotype
Genotype
Symbol: Braf/Braf<+> Ezh2/Ezh2<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
36206767 | J:330345
First Author: Li Y
Year: 2022
Journal: Mol Cell
Title: Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas.
Volume: 82
Issue: 20
Pages: 3901-3918.e7
•
•
•
•
•
Publication
33878291 | J:353209
First Author: Zhang W
Year: 2021
Journal: Cell
Title: The bone microenvironment invigorates metastatic seeds for further dissemination.
Volume: 184
Issue: 9
Pages: 2471-2486.e20
•
•
•
•
•
Publication
39137728 | J:353325
First Author: Yang Y
Year: 2024
Journal: Cancer Cell
Title: Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells.
Volume: 42
Issue: 8
Pages: 1434-1449.e5
•
•
•
•
•
Publication
32579914 | J:304690
First Author: Cheng Y
Year: 2020
Journal: Cell Rep
Title: NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Volume: 31
Issue: 12
Pages: 107782
•
•
•
•
•
Publication
38171333 | J:351130
First Author: Zhang Y
Year: 2024
Journal: Cell Metab
Title: Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer.
Volume: 36
Issue: 1
Pages: 193-208.e8
•
•
•
•
•
Publication
27653691 | J:239118
First Author: Nakanishi Y
Year: 2016
Journal: Cell Rep
Title: Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι.
Volume: 16
Issue: 12
Pages: 3297-3310
•
•
•
•
•
Publication
24162653 | J:207633
First Author: Li J
Year: 2013
Journal: Nat Neurosci
Title: EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia.
Volume: 16
Issue: 12
Pages: 1745-53
•
•
•
•
•
Publication
30257200 | J:269429
First Author: Nishiguchi MA
Year: 2018
Journal: Cell Rep
Title: Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.
Volume: 24
Issue: 13
Pages: 3383-3392.e5
•
•
•
•
•
Publication
28059767 | J:237907
First Author: Ku SY
Year: 2017
Journal: Science
Title: Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
Volume: 355
Issue: 6320
Pages: 78-83
•
•
•
•
•
Publication
30420438 | J:268313
First Author: Lim TJF
Year: 2018
Journal: J Immunol
Title: Talin1 Methylation Is Required for Neutrophil Infiltration and Lipopolysaccharide-Induced Lethality.
Volume: 201
Issue: 12
Pages: 3651-3661
•
•
•
•
•
Publication
28387316 | J:253496
 
First Author: Zhang H
Year: 2017
Journal: Nat Commun
Title: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Volume: 8
Pages: 14922
•
•
•
•
•
Publication
33207205 | J:323557
First Author: Wu J
Year: 2020
Journal: Cell Rep
Title: Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors.
Volume: 33
Issue: 7
Pages: 108395
•
•
•
•
•
Publication
29378702 | J:257561
 
First Author: Gu W
Year: 2018
Journal: Biol Open
Title: Dnd1-mediated epigenetic control of teratoma formation in mouse.
Volume: 7
Issue: 1
•
•
•
•
•
Publication
20368621 | J:158796
First Author: Szulwach KE
Year: 2010
Journal: J Cell Biol
Title: Cross talk between microRNA and epigenetic regulation in adult neurogenesis.
Volume: 189
Issue: 1
Pages: 127-41
•
•
•
•
•
Publication
23675307 | J:197130
First Author: Pommier AJ
Year: 2013
Journal: PLoS Genet
Title: Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice.
Volume: 9
Issue: 5
Pages: e1003483
•
•
•
•
•
Publication
29540569 | J:261078
First Author: Kuser-Abali G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.
Volume: 115
Issue: 13
Pages: 3452-3457
•
•
•
•
•
Publication
15493016 | J:94206
First Author: Ohhata T
Year: 2004
Journal: Genesis
Title: X-inactivation is stably maintained in mouse embryos deficient for histone methyl transferase G9a.
Volume: 40
Issue: 3
Pages: 151-6
•
•
•
•
•
Publication
23122289 | J:193722
First Author: Hidalgo I
Year: 2012
Journal: Cell Stem Cell
Title: Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest.
Volume: 11
Issue: 5
Pages: 649-62
•
•
•
•
•
Publication
33270606 | J:360998
 
First Author: Harro CM
Year: 2021
Journal: J Clin Invest
Title: Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.
Volume: 131
Issue: 3
•
•
•
•
•
Publication
30905620 | J:301425
First Author: Agarwal P
Year: 2019
Journal: Cell Stem Cell
Title: Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Volume: 24
Issue: 5
Pages: 769-784.e6
•
•
•
•
•
Publication
22896699 | J:191582
First Author: Xiong Y
Year: 2012
Journal: J Biol Chem
Title: Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner.
Volume: 287
Issue: 41
Pages: 34372-85
•
•
•
•
•
Publication
29021137 | J:271423
First Author: Huang S
Year: 2017
Journal: Cancer Res
Title: DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer.
Volume: 77
Issue: 23
Pages: 6562-6575
•
•
•
•
•
Publication
29174332 | J:250370
First Author: Lin B
Year: 2017
Journal: Cell Stem Cell
Title: Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency.
Volume: 21
Issue: 6
Pages: 761-774.e5
•
•
•
•
•
Publication
33878299 | J:305420
First Author: Bado IL
Year: 2021
Journal: Dev Cell
Title: The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells.
Volume: 56
Issue: 8
Pages: 1100-1117.e9
•
•
•
•
•
Publication
26551560 | J:228073
   
First Author: Zylicz JJ
Year: 2015
Journal: Elife
Title: Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development.
Volume: 4
•
•
•
•
•
Publication
24728351 | J:259254
First Author: Arvey A
Year: 2014
Journal: Nat Immunol
Title: Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells.
Volume: 15
Issue: 6
Pages: 580-587
•
•
•
•
•
Publication
37092728 | J:349175
   
First Author: Ramesh V
Year: 2023
Journal: Elife
Title: Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics.
Volume: 12
•
•
•
•
•
Publication
29590609 | J:270936
First Author: Fukumoto T
Year: 2018
Journal: Cell Rep
Title: Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer.
Volume: 22
Issue: 13
Pages: 3393-3400
•
•
•
•
•
Publication
30692537 | J:273464
First Author: Stewart ER
Year: 2019
Journal: Nat Commun
Title: Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term culture.
Volume: 10
Issue: 1
Pages: 460
•
•
•
•
•
Publication
22237151 | J:196546
First Author: Ntziachristos P
Year: 2012
Journal: Nat Med
Title: Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Volume: 18
Issue: 2
Pages: 298-301
•
•
•
•
•
Publication
23403289 | J:212599
First Author: Hahn MA
Year: 2013
Journal: Cell Rep
Title: Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.
Volume: 3
Issue: 2
Pages: 291-300
•
•
•
•
•
Publication
39383220 | J:355099
First Author: Zhang Y
Year: 2024
Journal: Sci Adv
Title: Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy.
Volume: 10
Issue: 41
Pages: eadq0479
•
•
•
•
•
Publication
23539183 | J:198210
First Author: Lewis PW
Year: 2013
Journal: Science
Title: Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
Volume: 340
Issue: 6134
Pages: 857-61
•
•
•
•
•
Publication
23645565 | J:205460
First Author: Larsson CA
Year: 2013
Journal: Mol Cancer Res
Title: The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome.
Volume: 11
Issue: 8
Pages: 815-27
•
•
•
•
•
Publication
24389103 | J:213022
First Author: Mozzetta C
Year: 2014
Journal: Mol Cell
Title: The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.
Volume: 53
Issue: 2
Pages: 277-89
•
•
•
•
•
Publication
24882207 | J:228104
First Author: Cifuentes-Rojas C
Year: 2014
Journal: Mol Cell
Title: Regulatory interactions between RNA and polycomb repressive complex 2.
Volume: 55
Issue: 2
Pages: 171-85
•
•
•
•
•
Publication
28461508 | J:242205
First Author: Dai YJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
Volume: 114
Issue: 20
Pages: 5237-5242
•
•
•
•
•
Publication
28892470 | J:260319
First Author: Kwon HK
Year: 2017
Journal: Nat Immunol
Title: Different molecular complexes that mediate transcriptional induction and repression by FoxP3.
Volume: 18
Issue: 11
Pages: 1238-1248
•
•
•
•
•
Publication
29681498 | J:262396
First Author: Lee CH
Year: 2018
Journal: Mol Cell
Title: Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
Volume: 70
Issue: 3
Pages: 435-448.e5
•
•
•
•
•
Publication
29808031 | J:268195
First Author: Perino M
Year: 2018
Journal: Nat Genet
Title: MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding.
Volume: 50
Issue: 7
Pages: 1002-1010
•
•
•
•
•
Publication
29567676 | J:302665
First Author: Shah MY
Year: 2018
Journal: Genome Res
Title: Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.
Volume: 28
Issue: 4
Pages: 432-447
•
•
•
•
•
Publication
37490911 | J:339933
     
First Author: Yang L
Year: 2023
Journal: Dev Cell
Title: The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms.
•
•
•
•
•
Publication
37491148 | J:340470
First Author: Mätlik K
Year: 2023
Journal: Genes Dev
Title: Histone bivalency regulates the timing of cerebellar granule cell development.
Volume: 37
Issue: 13-14
Pages: 570-589
•
•
•
•
•
Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein
Q6NXI8
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
•
•
•
•
•
Protein
Q91WA4
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
•
•
•
•
•
Protein
M0QWU0
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
•
•
•
•
•
Publication
24550525 | J:212032
First Author: Su X
Year: 2014
Journal: J Leukoc Biol
Title: Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors.
Volume: 96
Issue: 1
Pages: 17-26
•
•
•
•
•
Publication
20154697 | J:168268
First Author: Min J
Year: 2010
Journal: Nat Med
Title: An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.
Volume: 16
Issue: 3
Pages: 286-94
•
•
•
•
•
Publication
12370779 | J:78736
First Author: Wang J
Year: 2002
Journal: Mamm Genome
Title: The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.
Volume: 13
Issue: 9
Pages: 493-503
•
•
•
•
•
Publication
15916951 | J:99186
First Author: Montgomery ND
Year: 2005
Journal: Curr Biol
Title: The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation.
Volume: 15
Issue: 10
Pages: 942-7
•
•
•
•
•
Publication
26383163 | J:226779
First Author: Tian Y
Year: 2015
Journal: Cancer Res
Title: Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma.
Volume: 75
Issue: 22
Pages: 4803-16
•
•
•
•
•
Publication
29472543 | J:280454
First Author: Zheng S
Year: 2018
Journal: Cell Death Dis
Title: DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.
Volume: 9
Issue: 3
Pages: 310
•
•
•
•
•
Publication
25197075 | J:216364
First Author: Caprio C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome.
Volume: 111
Issue: 37
Pages: 13385-90
•
•
•
•
•
Publication
25252918 | J:217195
First Author: Santos M
Year: 2014
Journal: Cancer Res
Title: In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.
Volume: 74
Issue: 22
Pages: 6565-6577
•
•
•
•
•
Publication
26118502 | J:230773
First Author: Danis E
Year: 2015
Journal: Exp Hematol
Title: Inactivation of Eed impedes MLL-AF9-mediated leukemogenesis through Cdkn2a-dependent and Cdkn2a-independent mechanisms in a murine model.
Volume: 43
Issue: 11
Pages: 930-935.e6
•
•
•
•
•
Publication
37129912 | J:337744
First Author: Mohan DR
Year: 2023
Journal: Cancer Res
Title: β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.
Volume: 83
Issue: 13
Pages: 2123-2141
•
•
•
•
•
Publication
23144318 | J:194111
First Author: Rahal OM
Year: 2013
Journal: Carcinogenesis
Title: Suppression of Wnt1-induced mammary tumor growth and lower serum insulin in offspring exposed to maternal blueberry diet suggest early dietary influence on developmental programming.
Volume: 34
Issue: 2
Pages: 464-74
•
•
•
•
•
Publication
31736707 | J:289567
 
First Author: Yan HL
Year: 2019
Journal: Front Mol Neurosci
Title: MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice.
Volume: 12
Pages: 260
•
•
•
•
•
Publication
37934116 | J:360096
First Author: Saggese P
Year: 2024
Journal: Cancer Res
Title: Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma.
Volume: 84
Issue: 2
Pages: 305-327
•
•
•
•
•
Publication
35346967 | J:324712
First Author: Kania AK
Year: 2022
Journal: J Immunol
Title: H3K27me3 Demethylase UTX Restrains Plasma Cell Formation.
Volume: 208
Issue: 8
Pages: 1873-1885
•
•
•
•
•
Publication
31246581 | J:325935
First Author: He J
Year: 2019
Journal: J Clin Invest
Title: Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.
Volume: 129
Issue: 9
Pages: 3877-3893
•
•
•
•
•
Publication
37614965 | J:360481
First Author: Song P
Year: 2023
Journal: MedComm (2020)
Title: Cellular senescence primes liver fibrosis regression through Notch-EZH2.
Volume: 4
Issue: 5
Pages: e346
•
•
•
•
•
Publication
24491799 | J:209150
First Author: Ding L
Year: 2014
Journal: Cancer Res
Title: CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy.
Volume: 74
Issue: 7
Pages: 2050-61
•
•
•
•
•
Publication
22117046 | J:181783
First Author: He S
Year: 2012
Journal: Blood
Title: Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
Volume: 119
Issue: 5
Pages: 1274-82
•
•
•
•
•
Publication
22778136 | J:188797
First Author: Ross J
Year: 2012
Journal: Mol Cell Biol
Title: GATA-1 utilizes Ikaros and polycomb repressive complex 2 to suppress Hes1 and to promote erythropoiesis.
Volume: 32
Issue: 18
Pages: 3624-38
•
•
•
•
•
Publication
32025719 | J:286624
First Author: Liu F
Year: 2020
Journal: Nucleic Acids Res
Title: PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2.
Volume: 48
Issue: 6
Pages: 2956-2968
•
•
•
•
•
Publication
39511137 | J:358422
First Author: Zaretsky A
Year: 2024
Journal: Cell Death Dis
Title: SIRT6-dependent functional switch via K494 modifications of RE-1 silencing transcription factor.
Volume: 15
Issue: 11
Pages: 798
•
•
•
•
•
Publication
19144718 | J:144190
First Author: Redrup L
Year: 2009
Journal: Development
Title: The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing.
Volume: 136
Issue: 4
Pages: 525-30
•
•
•
•
•
Publication
28604389 | J:244997
First Author: Li Q
Year: 2017
Journal: J Clin Invest
Title: A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.
Volume: 127
Issue: 7
Pages: 2631-2646
•
•
•
•
•
Publication
31880094 | J:284066
First Author: Yang R
Year: 2020
Journal: Aging Cell
Title: 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis.
Volume: 19
Issue: 2
Pages: e13095
•
•
•
•
•
Publication
35906216 | J:359024
First Author: Su H
Year: 2022
Journal: Cell Death Dis
Title: LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Volume: 13
Issue: 7
Pages: 661
•
•
•
•
•
Publication
35338256 | J:323765
First Author: Yi SA
Year: 2022
Journal: Exp Mol Med
Title: S6K1 controls adiponectin expression by inducing a transcriptional switch: BMAL1-to-EZH2.
Volume: 54
Issue: 3
Pages: 324-333
•
•
•
•
•
Publication
29632194 | J:261483
First Author: Wu Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Volume: 115
Issue: 17
Pages: E3978-E3986
•
•
•
•
•
Publication
28827371 | J:245661
First Author: Jin L
Year: 2017
Journal: Cancer Res
Title: STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.
Volume: 77
Issue: 20
Pages: 5464-5478
•
•
•
•
•
Publication
38461418 | J:353685
First Author: Harada M
Year: 2024
Journal: Cell Cycle
Title: Sustained activation of NF-κB through constitutively active IKKβ leads to senescence bypass in murine dermal fibroblasts.
Volume: 23
Issue: 3
Pages: 308-327
•
•
•
•
•
Publication
32439758 | J:290852
 
First Author: Postlmayr A
Year: 2020
Journal: Development
Title: Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.
Volume: 147
Issue: 11
•
•
•
•
•
Publication
20818417 | J:168815
First Author: Hebbard L
Year: 2011
Journal: Oncogene
Title: Control of mammary tumor differentiation by SKI-606 (bosutinib).
Volume: 30
Issue: 3
Pages: 301-12
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom