| Type |
Details |
Score |
| Publication |
| First Author: |
Miyake M |
| Year: |
2021 |
| Journal: |
iScience |
| Title: |
Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity. |
| Volume: |
24 |
| Issue: |
12 |
| Pages: |
103448 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen C |
| Year: |
2020 |
| Journal: |
Mol Ther Methods Clin Dev |
| Title: |
Non-toxic HSC Transplantation-Based Macrophage/Microglia-Mediated GDNF Delivery for Parkinson's Disease. |
| Volume: |
17 |
|
| Pages: |
83-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garcia TX |
| Year: |
2017 |
| Journal: |
Stem Cells Dev |
| Title: |
The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. |
| Volume: |
26 |
| Issue: |
8 |
| Pages: |
585-598 |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; endonuclease-mediated mutation 1, Randy J Seeley |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watabe K |
| Year: |
1999 |
| Journal: |
GenBank Submission |
| Title: |
Mouse mRNA for GDNF receptor alpha, complete cds |
|
|
| Pages: |
AB000800 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Widenfalk J |
| Year: |
1998 |
| Journal: |
Eur J Neurosci |
| Title: |
GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
1508-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trupp M |
| Year: |
1998 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase. |
| Volume: |
11 |
| Issue: |
1-2 |
| Pages: |
47-63 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
238
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
8
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
13
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
25
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saarma M |
| Year: |
2000 |
| Journal: |
Eur J Biochem |
| Title: |
GDNF - a stranger in the TGF-beta superfamily? |
| Volume: |
267 |
| Issue: |
24 |
| Pages: |
6968-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frikke-Schmidt H |
| Year: |
2019 |
| Journal: |
Mol Metab |
| Title: |
GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice. |
| Volume: |
21 |
|
| Pages: |
13-21 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lisse TS |
| Year: |
2020 |
| Journal: |
NPJ Regen Med |
| Title: |
GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells. |
| Volume: |
5 |
|
| Pages: |
13 |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; endonuclease-mediated mutation 2, Randy J Seeley |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ledda F |
| Year: |
2007 |
| Journal: |
Nat Neurosci |
| Title: |
GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
293-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Decressac M |
| Year: |
2012 |
| Journal: |
Sci Transl Med |
| Title: |
α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons. |
| Volume: |
4 |
| Issue: |
163 |
| Pages: |
163ra156 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
301
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
302
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
300
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baloh RH |
| Year: |
1998 |
| Journal: |
Neuron |
| Title: |
Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. |
| Volume: |
21 |
| Issue: |
6 |
| Pages: |
1291-302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li Z |
| Year: |
2005 |
| Journal: |
J Neurochem |
| Title: |
Identification, expression and functional characterization of the GRAL gene. |
| Volume: |
95 |
| Issue: |
2 |
| Pages: |
361-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hiltunen PH |
| Year: |
2004 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Sympathetic cholinergic target innervation requires GDNF family receptor GFR alpha 2. |
| Volume: |
26 |
| Issue: |
3 |
| Pages: |
450-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Molliver DC |
| Year: |
1997 |
| Journal: |
Neuron |
| Title: |
IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. |
| Volume: |
19 |
| Issue: |
4 |
| Pages: |
849-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paveliev M |
| Year: |
2004 |
| Journal: |
Mol Cell Neurosci |
| Title: |
GDNF family ligands activate multiple events during axonal growth in mature sensory neurons. |
| Volume: |
25 |
| Issue: |
3 |
| Pages: |
453-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schober A |
| Year: |
2007 |
| Journal: |
Neurobiol Dis |
| Title: |
GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action. |
| Volume: |
25 |
| Issue: |
2 |
| Pages: |
378-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aravindakshan J |
| Year: |
2006 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Age-dependent bimodal GDNF regulation during ovarian tumorigenesis in follitropin receptor mutant mice. |
| Volume: |
351 |
| Issue: |
2 |
| Pages: |
507-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masaki K |
| Year: |
2018 |
| Journal: |
Stem Cell Reports |
| Title: |
FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
1782-1792 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
51
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blum M |
| Year: |
1995 |
| Journal: |
Neurobiol Aging |
| Title: |
GDNF mRNA expression in normal postnatal development, aging, and in Weaver mutant mice. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
925-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sagot Y |
| Year: |
1996 |
| Journal: |
J Neurosci |
| Title: |
GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. |
| Volume: |
16 |
| Issue: |
7 |
| Pages: |
2335-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cacalano G |
| Year: |
1998 |
| Journal: |
Neuron |
| Title: |
GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
53-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dudanova I |
| Year: |
2010 |
| Journal: |
Curr Biol |
| Title: |
GDNF acts as a chemoattractant to support ephrinA-induced repulsion of limb motor axons. |
| Volume: |
20 |
| Issue: |
23 |
| Pages: |
2150-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GarcÃa-Caballero C |
| Year: |
2018 |
| Journal: |
Mol Vis |
| Title: |
Photoreceptor preservation induced by intravitreal controlled delivery of GDNF and GDNF/melatonin in rhodopsin knockout mice. |
| Volume: |
24 |
|
| Pages: |
733-745 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li W |
| Year: |
2007 |
| Journal: |
Exp Neurol |
| Title: |
Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS. |
| Volume: |
203 |
| Issue: |
2 |
| Pages: |
457-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stanga S |
| Year: |
2018 |
| Journal: |
Front Neurol |
| Title: |
A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology. |
| Volume: |
9 |
|
| Pages: |
384 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jing S |
| Year: |
1997 |
| Journal: |
J Biol Chem |
| Title: |
GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family. |
| Volume: |
272 |
| Issue: |
52 |
| Pages: |
33111-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zwick M |
| Year: |
2001 |
| Journal: |
Exp Neurol |
| Title: |
Overexpression of GDNF induces and maintains hyperinnervation of muscle fibers and multiple end-plate formation. |
| Volume: |
171 |
| Issue: |
2 |
| Pages: |
342-50 |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ding LJ |
| Year: |
2011 |
| Journal: |
FEBS Lett |
| Title: |
FSH acts on the proliferation of type A spermatogonia via Nur77 that increases GDNF expression in the Sertoli cells. |
| Volume: |
585 |
| Issue: |
15 |
| Pages: |
2437-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson J |
| Year: |
1998 |
| Journal: |
Mol Cell Neurosci |
| Title: |
GFRalpha-4, a new GDNF family receptor. |
| Volume: |
11 |
| Issue: |
3 |
| Pages: |
117-26 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
endonuclease-mediated mutation, mutant stock |
|
•
•
•
•
•
|
| Publication |
|
| Year: |
1997 |
| Journal: |
Neuron |
| Title: |
Nomenclature of GPI-linked receptors for the GDNF ligand family. GFR(alpha) Nomenclature Committee. |
| Volume: |
19 |
| Issue: |
3 |
| Pages: |
485 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patel AR |
| Year: |
2023 |
| Journal: |
Am J Physiol Regul Integr Comp Physiol |
| Title: |
Neither GLP-1 receptors nor GFRAL neurons are required for aversive or anorectic response to DON (vomitoxin). |
| Volume: |
324 |
| Issue: |
5 |
| Pages: |
R635-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Salomova M |
| Year: |
2020 |
| Journal: |
Neurosci Lett |
| Title: |
Abnormalities in the cerebellar levels of trophic factors BDNF and GDNF in pcd and lurcher cerebellar mutant mice. |
| Volume: |
725 |
|
| Pages: |
134870 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cavel O |
| Year: |
2012 |
| Journal: |
Cancer Res |
| Title: |
Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor. |
| Volume: |
72 |
| Issue: |
22 |
| Pages: |
5733-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boger HA |
| Year: |
2008 |
| Journal: |
Brain Res |
| Title: |
Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene. |
| Volume: |
1241 |
|
| Pages: |
18-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng S |
| Year: |
2018 |
| Journal: |
Exp Neurol |
| Title: |
Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector. |
| Volume: |
309 |
|
| Pages: |
79-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee CS |
| Year: |
2005 |
| Journal: |
Exp Neurol |
| Title: |
Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells. |
| Volume: |
191 |
| Issue: |
1 |
| Pages: |
65-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2019 |
| Journal: |
Stem Cells |
| Title: |
AKT3 Is a Pivotal Molecule of Cadherin-22 and GDNF Family Receptor-α1 Signal Pathways Regulating Self-Renewal in Female Germline Stem Cells. |
| Volume: |
37 |
| Issue: |
8 |
| Pages: |
1095-1107 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
endonuclease-mediated mutation, mutant stock |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rossi J |
| Year: |
2003 |
| Journal: |
J Clin Invest |
| Title: |
Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor alpha2. |
| Volume: |
112 |
| Issue: |
5 |
| Pages: |
707-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Võikar V |
| Year: |
2004 |
| Journal: |
Eur J Neurosci |
| Title: |
Impaired behavioural flexibility and memory in mice lacking GDNF family receptor alpha2. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
308-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nivlet L |
| Year: |
2016 |
| Journal: |
J Mol Endocrinol |
| Title: |
Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas. |
| Volume: |
56 |
| Issue: |
2 |
| Pages: |
77-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mason I I |
| Year: |
1996 |
| Journal: |
Mol Cell Neurosci |
| Title: |
The GDNF Receptor: Recent Progress and Unanswered Questions |
| Volume: |
8 |
| Issue: |
2/3 |
| Pages: |
112-9 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soret R |
| Year: |
2021 |
| Journal: |
Int J Mol Sci |
| Title: |
Genetic Background Influences Severity of Colonic Aganglionosis and Response to GDNF Enemas in the Holstein Mouse Model of Hirschsprung Disease. |
| Volume: |
22 |
| Issue: |
23 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bozzi Y |
| Year: |
1999 |
| Journal: |
Eur J Neurosci |
| Title: |
Absence of the dopamine D2 receptor leads to a decreased expression of GDNF and NT-4 mRNAs in restricted brain areas. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
1275-84 |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; targeted mutation 1, Lexicon Pharmaceuticals |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; endonuclease-mediated mutation 1, Seiichi Oyadomari |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; endonuclease-mediated mutation 1, Stephen Liberles |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
GDNF family receptor alpha like; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|