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Search results 1101 to 1200 out of 1515 for Hnf4a

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5001143
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772123
Stage: TS23
Assay Id: MGI:5541699
Age: embryonic day 15.5
Image: GUDMAP:12531
Specimen Label: GUDMAP:12531
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3724420
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5421080
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH521; Specimen C1254
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:23345
Assay Type: RNA in situ
Annotation Date: 2009-06-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2778221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3846545
Age: embryonic day 13.5
Image: 5C,D
Specimen Label: 5C,D
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Probe: MGI:5001143
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2801123
Stage: TS23
Assay Id: MGI:5541699
Age: embryonic day 15.5
Image: GUDMAP:12531
Specimen Label: GUDMAP:12531
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724420
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2801128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5540382
Age: postnatal day 84
Image: GUDMAP:15748
Specimen Label: GUDMAP:15748
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:23345
Assay Type: RNA in situ
Annotation Date: 2009-06-03
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3846545
Age: embryonic day 9.5
Image: 3E,F
Note: Moderate expression in the midgut, including the primordium of the pancreas.
Specimen Label: 3E,F
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:23345
Assay Type: RNA in situ
Annotation Date: 2009-06-03
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3846545
Age: embryonic day 9.5
Image: 3G,H
Note: Moderate expression in the midgut, including the primordium of the pancreas.
Specimen Label: 3G,H
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:23345
Assay Type: RNA in situ
Annotation Date: 2009-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3846545
Age: embryonic day 13.5
Image: 5E,F
Note: Moderate to high expression extends from the midgut caudally through the hindgut, ending apparently within the endoderm approximately at the junction between the rectum and the anus.
Specimen Label: 5E,F
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_01
Specimen Label: euxassay_005745_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_02
Specimen Label: euxassay_005745_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_03
Specimen Label: euxassay_005745_03
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_04
Specimen Label: euxassay_005745_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_05
Specimen Label: euxassay_005745_05
Detected: true
Specimen Num: 5
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_06
Specimen Label: euxassay_005745_06
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_07
Specimen Label: euxassay_005745_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_08
Specimen Label: euxassay_005745_08
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_09
Specimen Label: euxassay_005745_09
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_10
Specimen Label: euxassay_005745_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_11
Specimen Label: euxassay_005745_11
Detected: true
Specimen Num: 11
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_12
Specimen Label: euxassay_005745_12
Detected: true
Specimen Num: 12
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•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_13
Specimen Label: euxassay_005745_13
Detected: true
Specimen Num: 13
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1581818
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825402
Age: embryonic day 14.5
Image: euxassay_005745_14
Specimen Label: euxassay_005745_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:3055326
Assay Type: Immunohistochemistry
Annotation Date: 2018-06-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3676826
Stage: TS26
Assay Id: MGI:6162547
Age: embryonic day 18.5
Image: 5K
Specimen Label: 5K
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3055326
Assay Type: Immunohistochemistry
Annotation Date: 2018-06-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3676826
Stage: TS26
Assay Id: MGI:6162547
Age: embryonic day 18.5
Image: 6I
Specimen Label: 6I
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3055326
Assay Type: Immunohistochemistry
Annotation Date: 2018-06-26
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3683924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6162546
Age: embryonic day 16.5
Image: 3E
Note: Authors state expression was essentially absent in extrahepatic bile duct.
Specimen Label: 3E
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3055326
Assay Type: Immunohistochemistry
Annotation Date: 2018-06-26
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3683924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6162546
Age: embryonic day 16.5
Image: 3G
Note: Authors report very weak expression in extrahepatic bile duct.
Specimen Label: 3G
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3055326
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3800024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7709229
Age: embryonic day 16.0
Note: Expression was detected in the late nephrogenic epithelial tissues.
Specimen Label: 7b
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7356406
Age: embryonic day 5.5
Image: S4B
Note: Lower expression compared with the extraembryonic visceral endoderm.
Specimen Label: S4B
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:381339
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7356406
Age: embryonic day 6.5
Image: 8B
Note: Lower expression compared with the extraembryonic visceral endoderm.
Specimen Label: 8B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:381339
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7356406
Age: embryonic day 6.5
Image: 8A
Note: Lower expression compared with the extraembryonic visceral endoderm.
Specimen Label: 8A
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:381337
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7356406
Age: embryonic day 5.5
Image: S4A
Note: Lower expression compared with the extraembryonic visceral endoderm.
Specimen Label: S4A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Trace
Sex: Male
Emaps: EMAPS:3813311
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:7356406
Age: embryonic day 7.5
Image: 8C
Note: Expression became restricted to the extraembryonic visceral endoderm. Only expressed in a few cells near the boundary between extraembryonic and embryonic portions of the embryo.
Specimen Label: 8C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7356402
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:3813311
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:7356406
Age: embryonic day 7.5
Image: 8D
Note: Increased ectopically throughout the visceral endoderm.
Specimen Label: 8D
Detected: true
Specimen Num: 4
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Publication
21274867 | J:308390
First Author: Guan M
Year: 2011
Journal: Hepatology
Title: Hepatocyte nuclear factor-4 alpha regulates liver triglyceride metabolism in part through secreted phospholipase Aâ‚‚ GXIIB.
Volume: 53
Issue: 2
Pages: 458-66
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Publication
30179226 | J:266392
First Author: Caratti G
Year: 2018
Journal: J Clin Invest
Title: REVERBa couples the circadian clock to hepatic glucocorticoid action.
Volume: 128
Issue: 10
Pages: 4454-4471
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Publication
25598084 | J:345375
First Author: Ning M
Year: 2015
Journal: Biochem Pharmacol
Title: Hepatocyte nuclear factor (HNF) 4α transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice.
Volume: 94
Issue: 1
Pages: 46-52
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Publication
26792861 | J:320681
First Author: Moore BD
Year: 2016
Journal: J Biol Chem
Title: Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function.
Volume: 291
Issue: 12
Pages: 6146-57
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Publication
33503426 | J:320837
First Author: Chen L
Year: 2021
Journal: Cell Rep
Title: Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4.
Volume: 34
Issue: 4
Pages: 108679
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Publication
11994307 | J:77808
First Author: Inoue Y
Year: 2002
Journal: J Biol Chem
Title: Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo.
Volume: 277
Issue: 28
Pages: 25257-65
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Publication
19898610 | J:158289
First Author: Darsigny M
Year: 2009
Journal: PLoS One
Title: Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.
Volume: 4
Issue: 10
Pages: e7609
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Publication
28877455 | J:271997
First Author: Simcox J
Year: 2017
Journal: Cell Metab
Title: Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
Volume: 26
Issue: 3
Pages: 509-522.e6
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Publication
25829452 | J:246317
First Author: Baraille F
Year: 2015
Journal: Diabetes
Title: Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage.
Volume: 64
Issue: 8
Pages: 2744-56
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Publication
34170569 | J:345496
First Author: Gárate-Rascón M
Year: 2021
Journal: Hepatology
Title: Splicing Factor SLU7 Prevents Oxidative Stress-Mediated Hepatocyte Nuclear Factor 4α Degradation, Preserving Hepatic Differentiation and Protecting From Liver Damage.
Volume: 74
Issue: 5
Pages: 2791-2807
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Publication
27166517 | J:233893
   
First Author: Chellappa K
Year: 2016
Journal: Elife
Title: Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.
Volume: 5
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Publication
30944208 | J:290734
First Author: An Y
Year: 2019
Journal: Mol Pharmacol
Title: An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury.
Volume: 95
Issue: 6
Pages: 597-605
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Publication
29023917 | J:270024
First Author: Zhao J
Year: 2018
Journal: Hepatology
Title: Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice.
Volume: 67
Issue: 3
Pages: 1109-1126
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Publication
7615825 | J:28121
First Author: Ginsburg GS
Year: 1995
Journal: J Clin Invest
Title: Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4.
Volume: 96
Issue: 1
Pages: 528-38
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Publication
11731232 | J:73291
First Author: Torres-Padilla ME
Year: 2001
Journal: Mech Dev
Title: Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing.
Volume: 109
Issue: 2
Pages: 183-93
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Publication
15928313 | J:100404
First Author: Archer A
Year: 2005
Journal: Mol Endocrinol
Title: Intestinal apolipoprotein A-IV gene transcription is controlled by two hormone-responsive elements: a role for hepatic nuclear factor-4 isoforms.
Volume: 19
Issue: 9
Pages: 2320-34
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Publication
12107181 | J:119431
First Author: Louet JF
Year: 2002
Journal: J Biol Chem
Title: The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB).
Volume: 277
Issue: 41
Pages: 37991-8000
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Publication
18474611 | J:137444
First Author: Perilhou A
Year: 2008
Journal: Mol Cell Biol
Title: The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells.
Volume: 28
Issue: 14
Pages: 4588-97
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Publication
18483185 | J:138664
First Author: Geier A
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene.
Volume: 295
Issue: 2
Pages: G226-33
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Publication
20378774 | J:160173
First Author: Schmidt D
Year: 2010
Journal: Science
Title: Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.
Volume: 328
Issue: 5981
Pages: 1036-40
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Publication
22139130 | J:203611
First Author: Garibaldi F
Year: 2012
Journal: Cell Death Differ
Title: An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.
Volume: 19
Issue: 6
Pages: 937-46
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Publication
28536011 | J:243200
 
First Author: Huang Q
Year: 2017
Journal: Cancer Lett
Title: Tg737 regulates epithelial-mesenchymal transition and cancer stem cell properties via a negative feedback circuit between Snail and HNF4α during liver stem cell malignant transformation.
Volume: 402
Pages: 52-60
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Publication
32057145 | J:304937
First Author: Zhou J
Year: 2020
Journal: FASEB J
Title: Hepatocyte nuclear factor 4α negatively regulates connective tissue growth factor during liver regeneration.
Volume: 34
Issue: 4
Pages: 4970-4983
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Publication
24277929 | J:325517
First Author: Shi X
Year: 2014
Journal: Mol Cell Biol
Title: Cholesterol sulfate and cholesterol sulfotransferase inhibit gluconeogenesis by targeting hepatocyte nuclear factor 4α.
Volume: 34
Issue: 3
Pages: 485-97
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Publication
12891557 | J:228417
First Author: Claudel T
Year: 2003
Journal: Gastroenterology
Title: Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.
Volume: 125
Issue: 2
Pages: 544-55
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Publication
21071704 | J:184185
First Author: Yin L
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Hepatic hepatocyte nuclear factor 4α is essential for maintaining triglyceride and cholesterol homeostasis.
Volume: 31
Issue: 2
Pages: 328-36
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Publication
31953394 | J:283737
First Author: Da Li
Year: 2020
Journal: Nat Commun
Title: Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.
Volume: 11
Issue: 1
Pages: 342
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Publication
26100857 | J:223016
 
First Author: Xu Y
Year: 2015
Journal: Nat Commun
Title: A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism.
Volume: 6
Pages: 7466
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First Author: Martinez-Jimenez CP
Year: 2010
Journal: Mol Cell Biol
Title: Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.
Volume: 30
Issue: 3
Pages: 565-77
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23967086 | J:206357
First Author: Konstandi M
Year: 2013
Journal: PLoS One
Title: Role of PPARα and HNF4α in stress-mediated alterations in lipid homeostasis.
Volume: 8
Issue: 8
Pages: e70675
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15282747 | J:92294
First Author: Vincent SD
Year: 2004
Journal: Genesis
Title: Targeted insertion of an IRES Cre into the Hnf4alpha locus: Cre-mediated recombination in the liver, kidney, and gut epithelium.
Volume: 39
Issue: 3
Pages: 206-11
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23209428 | J:194672
First Author: Menezes LF
Year: 2012
Journal: PLoS Genet
Title: Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier.
Volume: 8
Issue: 11
Pages: e1003053
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32631996 | J:292265
First Author: Wu H
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.
Volume: 117
Issue: 29
Pages: 17177-17186
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First Author: Koh KH
Year: 2014
Journal: J Biol Chem
Title: Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice.
Volume: 289
Issue: 6
Pages: 3105-13
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32553626 | J:304217
First Author: Kasano-Camones CI
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Synergistic regulation of hepatic Fsp27b expression by HNF4α and CREBH.
Volume: 530
Issue: 2
Pages: 432-439
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28465351 | J:245976
First Author: Morimoto A
Year: 2017
Journal: J Biol Chem
Title: An HNF4α-microRNA-194/192 signaling axis maintains hepatic cell function.
Volume: 292
Issue: 25
Pages: 10574-10585
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24066149 | J:207540
First Author: Safdar H
Year: 2013
Journal: PLoS One
Title: Regulation of the F11, Klkb1, Cyp4v3 gene cluster in livers of metabolically challenged mice.
Volume: 8
Issue: 9
Pages: e74637
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26527688 | J:227413
First Author: Matsuo S
Year: 2015
Journal: J Biol Chem
Title: Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver.
Volume: 290
Issue: 52
Pages: 30855-65
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First Author: Holloway MG
Year: 2006
Journal: Mol Endocrinol
Title: Codependence of growth hormone-responsive, sexually dimorphic hepatic gene expression on signal transducer and activator of transcription 5b and hepatic nuclear factor 4alpha.
Volume: 20
Issue: 3
Pages: 647-60
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30341289 | J:267959
First Author: Fekry B
Year: 2018
Journal: Nat Commun
Title: Incompatibility of the circadian protein BMAL1 and HNF4α in hepatocellular carcinoma.
Volume: 9
Issue: 1
Pages: 4349
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34001900 | J:306097
First Author: Chen L
Year: 2021
Journal: Nat Commun
Title: The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac.
Volume: 12
Issue: 1
Pages: 2886
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16714383 | J:110205
First Author: Battle MA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver.
Volume: 103
Issue: 22
Pages: 8419-24
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First Author: Sadagurski M
Year: 2006
Journal: Mol Cell Biol
Title: Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
Volume: 26
Issue: 7
Pages: 2675-87
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First Author: Wagener R
Year: 2001
Journal: Genomics
Title: Characterization of the mouse matrilin-4 gene: a 5' antiparallel overlap with the gene encoding the transcription factor RBP-l.
Volume: 76
Issue: 1-3
Pages: 89-98
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First Author: Duncan SA
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.
Volume: 91
Issue: 16
Pages: 7598-602
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12651943 | J:82753
First Author: Rhee J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis.
Volume: 100
Issue: 7
Pages: 4012-7
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17485727 | J:123777
First Author: Dongol B
Year: 2007
Journal: J Lipid Res
Title: The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter.
Volume: 48
Issue: 8
Pages: 1781-91
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First Author: Kanazawa T
Year: 2009
Journal: Anat Histol Embryol
Title: Expression of hepatocyte nuclear factor 4alpha in developing mice.
Volume: 38
Issue: 1
Pages: 34-41
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19188435 | J:151129
First Author: Boj SF
Year: 2009
Journal: Diabetes
Title: Functional targets of the monogenic diabetes transcription factors HNF-1alpha and HNF-4alpha are highly conserved between mice and humans.
Volume: 58
Issue: 5
Pages: 1245-53
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20421289 | J:176768
First Author: De Souza CT
Year: 2010
Journal: J Physiol
Title: Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.
Volume: 588
Issue: Pt 12
Pages: 2239-53
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First Author: Caron S
Year: 2013
Journal: Mol Cell Biol
Title: Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes.
Volume: 33
Issue: 11
Pages: 2202-11
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First Author: Sun Q
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease.
Volume: 307
Issue: 3
Pages: G313-22
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First Author: Zhang H
Year: 2020
Journal: J Biol Chem
Title: Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease.
Volume: 295
Issue: 12
Pages: 3891-3905
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32749667 | J:297444
First Author: Tan SY
Year: 2020
Journal: FEBS Lett
Title: CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression.
Volume: 594
Issue: 19
Pages: 3227-3239
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34048961 | J:318686
 
First Author: Kuo T
Year: 2021
Journal: Mol Metab
Title: Antagonistic epistasis of Hnf4α and FoxO1 metabolic networks through enhancer interactions in β-cell function.
Volume: 53
Pages: 101256
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First Author: Thomas AM
Year: 2013
Journal: Pharm Res
Title: Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale.
Volume: 30
Issue: 9
Pages: 2188-98
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First Author: Stegmann A
Year: 2006
Journal: Physiol Genomics
Title: Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.
Volume: 27
Issue: 2
Pages: 141-55
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17636037 | J:125929
First Author: Ponugoti B
Year: 2007
Journal: Mol Endocrinol
Title: Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c.
Volume: 21
Issue: 11
Pages: 2698-712
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Publication
38582490 | J:347881
 
First Author: Pan X
Year: 2024
Journal: Metabolism
Title: Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.
Volume: 155
Pages: 155909
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First Author: Saéz-López C
Year: 2015
Journal: Endocrinology
Title: SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development.
Volume: 156
Issue: 12
Pages: 4571-81
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First Author: Saandi T
Year: 2013
Journal: Oncogene
Title: Regulation of the tumor suppressor homeogene Cdx2 by HNF4α in intestinal cancer.
Volume: 32
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Pages: 3782-8
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Journal: Dev Dyn
Title: Apoptosis in mouse embryos: elevated levels in pregastrulae and in the distal anterior region of gastrulae of normal and mutant mice.
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First Author: Liu D
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Journal: Mol Ther
Title: Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease.
Volume: 25
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Pages: 752-764
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First Author: Luebke-Wheeler J
Year: 2008
Journal: Hepatology
Title: Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.
Volume: 48
Issue: 4
Pages: 1242-50
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First Author: Bushkofsky JR
Year: 2016
Journal: Arch Biochem Biophys
Title: Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα.
Volume: 597
Pages: 30-47
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First Author: Chen WS
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Journal: Genes Dev
Title: Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.
Volume: 8
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Pages: 2466-77
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First Author: Duncan SA
Year: 1997
Journal: Development
Title: Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos.
Volume: 124
Issue: 2
Pages: 279-87
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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