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Search results 1101 to 1182 out of 1182 for Hoxb1

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Type Details Score
Genotype
Symbol: Hoxb/Hoxb<+>
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Vogel M
Year: 2016
Journal: Am J Med Genet A
Title: Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis.
Volume: 170
Issue: 7
Pages: 1813-9
Publication
First Author: Han L
Year: 2015
Journal: PLoS One
Title: HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma.
Volume: 10
Issue: 11
Pages: e0142387
GXD Expression
Probe: MGI:1309443
Assay Type: RNA in situ
Annotation Date: 2002-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2155488
Age: embryonic day 8.0
Image: 5C''
Note: In this mutant the region of expression expands posteriorly and fuses with the Hoxb1 expression domain.
Specimen Label: 5C''
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:1309443
Assay Type: RNA in situ
Annotation Date: 2002-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2155488
Age: embryonic day 8.0
Image: 5E''
Note: In this mutant the region of expression expands posteriorly and fuses with the Hoxb1 expression domain.
Specimen Label: 5E''
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:6430402
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673013
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6430410
Age: embryonic day 8.5
Image: S3B/C
Note: Co-expression with Hoxb1 in splanchnic mesoderm (subdomain of second heart field).
Specimen Label: S3B/C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1927799
Assay Type: RNA in situ
Annotation Date: 2001-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614812
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:1928497
Age: embryonic day 8.0
Image: 4. D.
Note: Expression is present in a single domain in the hindbrain and does not overlap with Hoxa1 or Hoxb1 expression.
Specimen Label: 4. D.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1342972
Assay Type: RNA in situ
Annotation Date: 1999-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1650015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1343857
Age: embryonic day 9.5
Image: 2H
Note: The rostral limit of Hoxb4 expression is equivalent to the caudal limit of Hoxb1 expression, presumably at R5/6.
Specimen Label: 2H
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1342972
Assay Type: RNA in situ
Annotation Date: 1999-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1650815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1343857
Age: embryonic day 9.5
Image: 2H
Note: The rostral limit of Hoxb4 expression is equivalent to the caudal limit of Hoxb1 expression, presumably at R5/6.
Specimen Label: 2H
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:26910
Assay Type: RNA in situ
Annotation Date: 1999-03-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607311
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:1331440
Age: embryonic day 7.75
Image: 6C
Note: There is a stripe of Gbx2 expression in posterior neuroectoderm cells that expresses neither Hoxb1 nor Otx2.
Specimen Label: 6C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1342972
Assay Type: RNA in situ
Annotation Date: 1999-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1650415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1343857
Age: embryonic day 9.5
Image: 2H
Note: The rostral limit of Hoxb4 expression is equivalent to the caudal limit of Hoxb1 expression, presumably at R5/6.
Specimen Label: 2H
Detected: true
Specimen Num: 2
Allele
Name: transgene insertion 1, Stephane Zaffran
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: homeobox B1; targeted mutation 6, Mario R Capecchi
Allele Type: Targeted
Attribute String: Recombinase
GXD Expression
Probe: MGI:1927799
Assay Type: RNA in situ
Annotation Date: 2001-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614812
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:1928497
Age: embryonic day 8.5
Image: 4. H.
Note: Expression is present in a single domain in the hindbrain and does not overlap with Hoxa1 or Hoxb1 expression. This domain extends more posteriorly than at day 8.
Specimen Label: 4. H.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:28459
Assay Type: RNA in situ
Annotation Date: 2013-11-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614814
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:5520063
Age: embryonic day 9.0
Image: 3I
Note: There is a gap in expression between the Hoxb1 expressing rhombomere 4 domain and the HNF1 (Hnf1b) expression domain which is posterior to the rhombomere 6/7 boundary.
Specimen Label: 3I
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:28459
Assay Type: RNA in situ
Annotation Date: 2013-11-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614814
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:5520063
Age: embryonic day 9.0
Image: 3J
Note: There is a gap in expression between the Hoxb1 expressing rhombomere 4 domain and the HNF1 (Hnf1b) expression domain which is posterior to the rhombomere 6/7 boundary.
Specimen Label: 3J
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:28459
Assay Type: RNA in situ
Annotation Date: 2013-11-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614814
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:5520063
Age: embryonic day 9.0
Image: 3D
Note: There is a gap in expression between the Hoxb1 expressing rhombomere 4 domain and the HNF1 (Hnf1b) expression domain which is posterior to the rhombomere 6/7 boundary.
Specimen Label: 3D
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1276057
Assay Type: Immunohistochemistry
Annotation Date: 2018-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6121420
Age: embryonic day 8.5
Note: The expression domain was normal in the mutant. The En and Hoxb1 domains of expression relative to each other were similar to that seen in normal littermates.
Specimen Label: 5J
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1276057
Assay Type: Immunohistochemistry
Annotation Date: 2018-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6121427
Age: embryonic day 8.5
Note: The expression domain was normal in the mutant. The En and Hoxb1 domains of expression relative to each other were similar to that seen in normal littermates.
Specimen Label: 5J
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:36180
Assay Type: RNA in situ
Annotation Date: 2012-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609813
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5437457
Age: embryonic day 8.5
Image: 3N
Note: Expression was detected in mesenchymal cells localized posterior to Hoxb1 expression in rhombomere 4 and separate from neural crest cells adjacent to rhombomere 4.
Specimen Label: 3N
Detected: true
Specimen Num: 10
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Bijl J
Year: 2006
Journal: Blood
Title: Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells.
Volume: 108
Issue: 1
Pages: 116-22
Allele  
Name: homeobox B1; targeted mutation 1, Mario R Capecchi
Allele Type: Targeted
Allele
Name: homeobox B1; targeted mutation 5, Mario R Capecchi
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxb1/Hoxb1<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Allele
Name: homeobox B1; targeted mutation 2, Mario R Capecchi
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Hoxb1/Hoxb1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Del(6Hoxa)1Ddu/Del(6Hoxa)1Ddu Hoxb/Hoxb
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxb1/Hoxb1<+> Neurog2/Neurog2
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxb1/Hoxb1<+> Sox10/Sox10
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline and WT vs. Mutant
Source: ArrayExpress
Genotype
Symbol: Hoxb1/Hoxb1<+> Nodal/Nodal
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Allele
Name: deletion, Chr 11, Bradley 19; deletion, Chr 11, Allan Bradley 19
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: transgene insertion r4, Michele Studer
Allele Type: Transgenic
Attribute String: Recombinase
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: mutant stock, transgenic
Genotype
Symbol: Hoxa1/Hoxa1<+> Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1 Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Del(11Chad-Hoxb1)19Brd/+
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1 Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1 Hoxb1/Hoxb1<+>
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1<+> Hoxb1/Hoxb1<+>
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1<+> Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Allele  
Name: sasquatch
Allele Type: Transgenic
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Vieux-Rochas M
Year: 2013
Journal: Dev Biol
Title: Combined function of HoxA and HoxB clusters in neural crest cells.
Volume: 382
Issue: 1
Pages: 293-301
Publication
First Author: Itasaki N
Year: 1996
Journal: Neuron
Title: Reprogramming Hox expression in the vertebrate hindbrain: influence of paraxial mesoderm and rhombomere transposition.
Volume: 16
Issue: 3
Pages: 487-500
Publication
First Author: Sharpe J
Year: 1999
Journal: Curr Biol
Title: Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch.
Volume: 9
Issue: 2
Pages: 97-100
Genotype
Symbol: Hoxb1/Hoxb1 Tfap2a/Tfap2a<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1 Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ssq/?
Background: involves: C57BL/6 * C57BL/10 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ssq/Ssq
Background: involves: C57BL/6 * C57BL/10 * CBA
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: B6.129S2-Hoxb1/Cnrm
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Lettice LA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.
Volume: 99
Issue: 11
Pages: 7548-53
Publication
First Author: Basaldella E
Year: 2015
Journal: Cell
Title: Multisensory Signaling Shapes Vestibulo-Motor Circuit Specificity.
Volume: 163
Issue: 2
Pages: 301-12
Publication  
First Author: Lunde A
Year: 2019
Journal: eNeuro
Title: Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups.
Volume: 6
Issue: 1
Genotype
Symbol: Hoxb1/Hoxb1 H2az2/H2az2<+>
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hoxa1/Hoxa1 Hoxb1/Hoxb1
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1 Nkx2-2/Nkx2-2<+>
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1 Tg(Hoxb1-cre)r4Mist/?
Background: involves: 129S2/SvPas * CD-1
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sanna-Cherchi S
Year: 2017
Journal: Am J Hum Genet
Title: Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.
Volume: 101
Issue: 5
Pages: 789-802
Publication
First Author: d Graaff W
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants.
Volume: 100
Issue: 23
Pages: 13362-7
Publication
First Author: Roberts C
Year: 2006
Journal: Hum Mol Genet
Title: Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick.
Volume: 15
Issue: 23
Pages: 3394-410
Publication
First Author: Sun JJ
Year: 2017
Journal: Sci Rep
Title: Embryonic hindbrain patterning genes delineate distinct cardio-respiratory and metabolic homeostatic populations in the adult.
Volume: 7
Issue: 1
Pages: 9117
Publication
First Author: LaRonde-LeBlanc NA
Year: 2003
Journal: Genes Dev
Title: Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior.
Volume: 17
Issue: 16
Pages: 2060-72
Publication
First Author: Furutera T
Year: 2017
Journal: Development
Title: Differing contributions of the first and second pharyngeal arches to tympanic membrane formation in the mouse and chick.
Volume: 144
Issue: 18
Pages: 3315-3324
Genotype
Symbol: Hoxb1/Hoxb1 Tg(Hoxb1-cre)r4Mist/? Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hoxb1/Hoxb1 Tg(Hoxb1-cre)r4Mist/? Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Maguire M
Year: 2020
Journal: PLoS One
Title: Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
Volume: 15
Issue: 2
Pages: e0228436
Publication
First Author: Jacobs Y
Year: 1999
Journal: Mol Cell Biol
Title: Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity.
Volume: 19
Issue: 7
Pages: 5134-42
Publication
First Author: Thompson JR
Year: 1998
Journal: Dev Dyn
Title: An evolutionary conserved element is essential for somite and adjacent mesenchymal expression of the Hoxa1 gene.
Volume: 211
Issue: 1
Pages: 97-108
Publication
First Author: Soshnikova N
Year: 2013
Journal: Dev Biol
Title: Duplications of hox gene clusters and the emergence of vertebrates.
Volume: 378
Issue: 2
Pages: 194-9
Publication
First Author: Glasco DM
Year: 2016
Journal: Dev Biol
Title: The atypical cadherin Celsr1 functions non-cell autonomously to block rostral migration of facial branchiomotor neurons in mice.
Volume: 417
Issue: 1
Pages: 40-9
Publication  
First Author: Odelin G
Year: 2018
Journal: Development
Title: Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve.
Volume: 145
Issue: 1
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7