| Type |
Details |
Score |
| Publication |
| First Author: |
Allen IC |
| Year: |
2010 |
| Journal: |
J Exp Med |
| Title: |
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. |
| Volume: |
207 |
| Issue: |
5 |
| Pages: |
1045-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spurlock M |
| Year: |
2023 |
| Journal: |
Cells |
| Title: |
The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes. |
| Volume: |
12 |
| Issue: |
22 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gentile LF |
| Year: |
2015 |
| Journal: |
Immunology |
| Title: |
Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation. |
| Volume: |
145 |
| Issue: |
2 |
| Pages: |
300-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Halle A |
| Year: |
2008 |
| Journal: |
Nat Immunol |
| Title: |
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
857-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pillai PS |
| Year: |
2016 |
| Journal: |
Science |
| Title: |
Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. |
| Volume: |
352 |
| Issue: |
6284 |
| Pages: |
463-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Panicker N |
| Year: |
2022 |
| Journal: |
Neuron |
| Title: |
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. |
| Volume: |
110 |
| Issue: |
15 |
| Pages: |
2422-2437.e9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu J |
| Year: |
2021 |
| Journal: |
Immunity |
| Title: |
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis. |
| Volume: |
54 |
| Issue: |
11 |
| Pages: |
2632-2649.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee Y |
| Year: |
2012 |
| Journal: |
Circulation |
| Title: |
Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease. |
| Volume: |
125 |
| Issue: |
12 |
| Pages: |
1542-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zanoni I |
| Year: |
2016 |
| Journal: |
Science |
| Title: |
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. |
| Volume: |
352 |
| Issue: |
6290 |
| Pages: |
1232-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Conos SA |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner. |
| Volume: |
114 |
| Issue: |
6 |
| Pages: |
E961-E969 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Case CL |
| Year: |
2009 |
| Journal: |
Infect Immun |
| Title: |
Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. |
| Volume: |
77 |
| Issue: |
5 |
| Pages: |
1981-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Netea MG |
| Year: |
2001 |
| Journal: |
Eur J Immunol |
| Title: |
Lethal Escherichia coli and Salmonella typhimurium endotoxemia is mediated through different pathways. |
| Volume: |
31 |
| Issue: |
9 |
| Pages: |
2529-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lima-Junior DS |
| Year: |
2017 |
| Journal: |
J Immunol |
| Title: |
Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication. |
| Volume: |
199 |
| Issue: |
6 |
| Pages: |
2055-2068 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nascimento M |
| Year: |
2023 |
| Journal: |
Front Immunol |
| Title: |
NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner. |
| Volume: |
14 |
|
| Pages: |
1224383 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pinho-Ribeiro FA |
| Year: |
2018 |
| Journal: |
Cell |
| Title: |
Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection. |
| Volume: |
173 |
| Issue: |
5 |
| Pages: |
1083-1097.e22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kolly L |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF. |
| Volume: |
183 |
| Issue: |
6 |
| Pages: |
4003-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vaishnava S |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. |
| Volume: |
105 |
| Issue: |
52 |
| Pages: |
20858-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kotas ME |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Role of caspase-1 in regulation of triglyceride metabolism. |
| Volume: |
110 |
| Issue: |
12 |
| Pages: |
4810-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bumgardner SA |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
e0196950 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wallet P |
| Year: |
2017 |
| Journal: |
PLoS Pathog |
| Title: |
IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
e1006630 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alarcón-Vila C |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
López-Yglesias AH |
| Year: |
2014 |
| Journal: |
J Immunol |
| Title: |
Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway. |
| Volume: |
192 |
| Issue: |
4 |
| Pages: |
1587-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang MJ |
| Year: |
2017 |
| Journal: |
Immunology |
| Title: |
NLRP3 inflammasome mediates interleukin-1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice. |
| Volume: |
150 |
| Issue: |
4 |
| Pages: |
495-505 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McCoy AJ |
| Year: |
2010 |
| Journal: |
Eur J Immunol |
| Title: |
Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages. |
| Volume: |
40 |
| Issue: |
10 |
| Pages: |
2797-803 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zaki MH |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. |
| Volume: |
185 |
| Issue: |
8 |
| Pages: |
4912-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones HD |
| Year: |
2014 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. |
| Volume: |
50 |
| Issue: |
2 |
| Pages: |
270-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matusiak M |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5. |
| Volume: |
112 |
| Issue: |
5 |
| Pages: |
1541-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gustin A |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes. |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0130624 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guey B |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function. |
| Volume: |
111 |
| Issue: |
48 |
| Pages: |
17254-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eisenbarth SC |
| Year: |
2008 |
| Journal: |
Nature |
| Title: |
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. |
| Volume: |
453 |
| Issue: |
7198 |
| Pages: |
1122-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin Q |
| Year: |
2021 |
| Journal: |
Autophagy |
| Title: |
Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy. |
| Volume: |
17 |
| Issue: |
10 |
| Pages: |
2975-2990 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhivaki D |
| Year: |
2024 |
| Journal: |
Cell |
| Title: |
Correction of age-associated defects in dendritic cells enables CD4(+) T cells to eradicate tumors. |
| Volume: |
187 |
| Issue: |
15 |
| Pages: |
3888-3903.e18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimada K |
| Year: |
2012 |
| Journal: |
Immunity |
| Title: |
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. |
| Volume: |
36 |
| Issue: |
3 |
| Pages: |
401-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skeldon AM |
| Year: |
2016 |
| Journal: |
J Immunol |
| Title: |
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. |
| Volume: |
196 |
| Issue: |
1 |
| Pages: |
437-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hirata Y |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
TAK1-JNK axis mediates survival signal through Mcl1 stabilization in activated T cells. |
| Volume: |
190 |
| Issue: |
9 |
| Pages: |
4621-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerrick ER |
| Year: |
2024 |
| Journal: |
Cell |
| Title: |
Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition. |
| Volume: |
187 |
| Issue: |
1 |
| Pages: |
62-78.e20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi CS |
| Year: |
2012 |
| Journal: |
Nat Immunol |
| Title: |
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
255-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thurston TL |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. |
| Volume: |
7 |
|
| Pages: |
13292 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Almeida MQ |
| Year: |
2011 |
| Journal: |
Hum Mol Genet |
| Title: |
Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
165-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin YC |
| Year: |
2015 |
| Journal: |
J Leukoc Biol |
| Title: |
Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization. |
| Volume: |
97 |
| Issue: |
5 |
| Pages: |
825-835 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Solle M |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Altered cytokine production in mice lacking P2X(7) receptors. |
| Volume: |
276 |
| Issue: |
1 |
| Pages: |
125-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jarret A |
| Year: |
2020 |
| Journal: |
Cell |
| Title: |
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity. |
| Volume: |
180 |
| Issue: |
1 |
| Pages: |
50-63.e12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bauer DL |
| Year: |
2023 |
| Journal: |
J Immunol |
| Title: |
The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells. |
| Volume: |
210 |
| Issue: |
10 |
| Pages: |
1519-1530 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Warren SE |
| Year: |
2008 |
| Journal: |
J Immunol |
| Title: |
Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. |
| Volume: |
180 |
| Issue: |
11 |
| Pages: |
7558-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McCoy AJ |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection. |
| Volume: |
185 |
| Issue: |
11 |
| Pages: |
7077-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo W |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
2168 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dey N |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages. |
| Volume: |
9 |
| Issue: |
11 |
| Pages: |
e111539 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vesela B |
| Year: |
2015 |
| Journal: |
J Mol Histol |
| Title: |
Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue. |
| Volume: |
46 |
| Issue: |
4-5 |
| Pages: |
443-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Buck M |
| Year: |
2001 |
| Journal: |
Mol Cell |
| Title: |
C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
807-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu L |
| Year: |
2017 |
| Journal: |
J Crohns Colitis |
| Title: |
The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
737-750 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vercammen D |
| Year: |
1998 |
| Journal: |
J Exp Med |
| Title: |
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. |
| Volume: |
187 |
| Issue: |
9 |
| Pages: |
1477-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Araki T |
| Year: |
1999 |
| Journal: |
Exp Cell Res |
| Title: |
Caspase activity is required for nephrogenesis in the developing mouse metanephros. |
| Volume: |
248 |
| Issue: |
2 |
| Pages: |
423-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haass C |
| Year: |
1999 |
| Journal: |
Nature |
| Title: |
Apoptosis. Dead end for neurodegeneration? |
| Volume: |
399 |
| Issue: |
6733 |
| Pages: |
204-5, 207 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo Z |
| Year: |
2003 |
| Journal: |
Blood |
| Title: |
Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways. |
| Volume: |
102 |
| Issue: |
13 |
| Pages: |
4441-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Griffith JW |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. |
| Volume: |
183 |
| Issue: |
8 |
| Pages: |
5208-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohno T |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. |
| Volume: |
183 |
| Issue: |
12 |
| Pages: |
7890-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KA |
| Year: |
2012 |
| Journal: |
Int Immunol |
| Title: |
IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway. |
| Volume: |
24 |
| Issue: |
3 |
| Pages: |
147-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Erener S |
| Year: |
2012 |
| Journal: |
Mol Cell |
| Title: |
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. |
| Volume: |
46 |
| Issue: |
2 |
| Pages: |
200-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Man SM |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production. |
| Volume: |
191 |
| Issue: |
10 |
| Pages: |
5239-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karmakar M |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP. |
| Volume: |
7 |
|
| Pages: |
10555 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McClellan SA |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis. |
| Volume: |
12 |
| Issue: |
9 |
| Pages: |
e0185718 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Faro J |
| Year: |
2019 |
| Journal: |
Biol Reprod |
| Title: |
Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome†. |
| Volume: |
100 |
| Issue: |
5 |
| Pages: |
1290-1305 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gomez-Lopez N |
| Year: |
2019 |
| Journal: |
Biol Reprod |
| Title: |
Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†. |
| Volume: |
100 |
| Issue: |
5 |
| Pages: |
1306-1318 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu C |
| Year: |
2019 |
| Journal: |
Immunity |
| Title: |
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. |
| Volume: |
50 |
| Issue: |
6 |
| Pages: |
1401-1411.e4 |
|
•
•
•
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|
| Publication |
| First Author: |
Reinke S |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo. |
| Volume: |
30 |
| Issue: |
8 |
| Pages: |
2501-2511.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2020 |
| Journal: |
Cell Death Dis |
| Title: |
Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
470 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang J |
| Year: |
2016 |
| Journal: |
Cell Death Dis |
| Title: |
Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
e2363 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
574
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
576
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
574
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
573
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
576
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
573
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
614
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
567
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
570
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
685
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
614
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
640
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
567
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pierini R |
| Year: |
2012 |
| Journal: |
Cell Death Differ |
| Title: |
AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages. |
| Volume: |
19 |
| Issue: |
10 |
| Pages: |
1709-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sheedy FJ |
| Year: |
2013 |
| Journal: |
Nat Immunol |
| Title: |
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
812-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hornung V |
| Year: |
2009 |
| Journal: |
Nature |
| Title: |
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. |
| Volume: |
458 |
| Issue: |
7237 |
| Pages: |
514-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones JW |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. |
| Volume: |
107 |
| Issue: |
21 |
| Pages: |
9771-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nett MA |
| Year: |
1992 |
| Journal: |
J Immunol |
| Title: |
Molecular cloning of the murine IL-1 beta converting enzyme cDNA. |
| Volume: |
149 |
| Issue: |
10 |
| Pages: |
3254-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van de Craen M |
| Year: |
1997 |
| Journal: |
FEBS Lett |
| Title: |
Characterization of seven murine caspase family members. |
| Volume: |
403 |
| Issue: |
1 |
| Pages: |
61-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kayagaki N |
| Year: |
2015 |
| Journal: |
Nature |
| Title: |
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. |
| Volume: |
526 |
| Issue: |
7575 |
| Pages: |
666-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao Y |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. |
| Volume: |
477 |
| Issue: |
7366 |
| Pages: |
596-600 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boyden ED |
| Year: |
2006 |
| Journal: |
Nat Genet |
| Title: |
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. |
| Volume: |
38 |
| Issue: |
2 |
| Pages: |
240-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lara-Tejero M |
| Year: |
2006 |
| Journal: |
J Exp Med |
| Title: |
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. |
| Volume: |
203 |
| Issue: |
6 |
| Pages: |
1407-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Levy M |
| Year: |
2015 |
| Journal: |
Cell |
| Title: |
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. |
| Volume: |
163 |
| Issue: |
6 |
| Pages: |
1428-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mariathasan S |
| Year: |
2006 |
| Journal: |
Nature |
| Title: |
Cryopyrin activates the inflammasome in response to toxins and ATP. |
| Volume: |
440 |
| Issue: |
7081 |
| Pages: |
228-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu B |
| Year: |
2012 |
| Journal: |
Nature |
| Title: |
Novel role of PKR in inflammasome activation and HMGB1 release. |
| Volume: |
488 |
| Issue: |
7413 |
| Pages: |
670-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakamaki K |
| Year: |
1998 |
| Journal: |
Eur J Biochem |
| Title: |
Molecular cloning and characterization of mouse caspase-8. |
| Volume: |
253 |
| Issue: |
2 |
| Pages: |
399-405 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van de Craen M |
| Year: |
1998 |
| Journal: |
J Mol Biol |
| Title: |
Molecular cloning and identification of murine caspase-8. |
| Volume: |
284 |
| Issue: |
4 |
| Pages: |
1017-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fritsch M |
| Year: |
2019 |
| Journal: |
Nature |
| Title: |
Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. |
| Volume: |
575 |
| Issue: |
7784 |
| Pages: |
683-687 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ydens E |
| Year: |
2015 |
| Journal: |
J Neuroinflammation |
| Title: |
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes. |
| Volume: |
12 |
|
| Pages: |
143 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bruchard M |
| Year: |
2015 |
| Journal: |
Nat Immunol |
| Title: |
The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. |
| Volume: |
16 |
| Issue: |
8 |
| Pages: |
859-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guarda G |
| Year: |
2009 |
| Journal: |
Nature |
| Title: |
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. |
| Volume: |
460 |
| Issue: |
7252 |
| Pages: |
269-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moayeri M |
| Year: |
2010 |
| Journal: |
PLoS Pathog |
| Title: |
Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment. |
| Volume: |
6 |
| Issue: |
12 |
| Pages: |
e1001222 |
|
•
•
•
•
•
|