|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1101 to 1150 out of 1150 for Isl2

<< First    < Previous  |  Next >    Last >>
0.019s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
HT Experiment
GSE217297 | Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Allele
Igs2<em2(Rr518-lacZ)Axvi> | MGI:7713139
Name: intergenic site 2; endonuclease-mediated mutation 2, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Reporter
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7708043
Age: embryonic day 18.5
Image: 3a
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. Some RGC's were co-labeled with EdU when injected at E13.
Specimen Label: 3a
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7708043
Age: embryonic day 18.5
Image: 3b
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. The number of RGC's co-labeled with EdU was higher when injected at E14 than when injected at E13.
Specimen Label: 3b
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7708043
Age: embryonic day 18.5
Image: 3c
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. RGC proliferation, as determined by co-label with EdU, during late development was substantial until E15 and decreased thereafter.
Specimen Label: 3c
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2149733
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7708043
Age: embryonic day 18.5
Image: 3d
Note: Expression was detected in postmitotic retinal ganglion cells in the ventrotemporal retina. Co-label with Isl2 was seen in contralateral RGC's. RGC proliferation, as determined by co-label with EdU, was decreased when injected at E16 than when injected at previous ages.
Specimen Label: 3d
Detected: true
Specimen Num: 10
•
•
•
•
•
Allele
Tg(Isl2-EGFP)LW124Gsat | MGI:4847164
Name: transgene insertion LW124, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
Publication
28078709 | J:269911
First Author: Sweeney NT
Year: 2019
Journal: J Comp Neurol
Title: Expression of transcription factors divides retinal ganglion cells into distinct classes.
Volume: 527
Issue: 1
Pages: 225-235
•
•
•
•
•
Allele
Isl2<tm1(Epha3)Grl> | MGI:3056440
 
Name: insulin related protein 2 (islet 2); targeted mutation 1, Greg Lemke
Allele Type: Targeted
•
•
•
•
•
Strain
MGI:5004174 | STOCK Tg(Isl2-EGFP)LW124Gsat/Mmucd
Attribute String: mutant stock, transgenic
•
•
•
•
•
Publication
38420317 | J:350699
First Author: Zhang P
Year: 2023
Journal: Biomed Opt Express
Title: Evaluating the performance of OCT in assessing static and potential dynamic properties of the retinal ganglion cells and nerve fiber bundles in the living mouse eye.
Volume: 14
Issue: 12
Pages: 6422-6441
•
•
•
•
•
Genotype
Genotype
Symbol: Isl2/Isl2
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
23750000 | -
First Author: Gadd MS
Year: 2013
Journal: J Biol Chem
Title: A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
Volume: 288
Issue: 30
Pages: 21924-35
•
•
•
•
•
Protein Domain
IPR041363 | LID
Type: Domain
Description: LIM-homeodomain (LIM-HD) proteins are transcription factors that are critical in the development of many cell types and tissues. The activity of LIM-HD proteins is dependent on the essential cofactor LIM domain-binding protein 1 (Ldb1). This entry represents a 30-residue LIM interaction domain (LID) that binds to the LIM domains of all LIM-HD and closely related LIM-only (LMO) proteins. Isl1 (Insulin gene enhancer protein 1) and Isl2 each contain a LID-like sequence in their C-terminal regions, the Lhx3-binding domain (LBD), which binds the LIM domains Lhx3 and Lhx4 [].
•
•
•
•
•
Protein
O55203
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
•
•
•
•
•
Protein
A0A0G2JFS7
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: false
•
•
•
•
•
Publication
27170123 | J:231954
First Author: Shanks JA
Year: 2016
Journal: J Neurosci
Title: Corticothalamic Axons Are Essential for Retinal Ganglion Cell Axon Targeting to the Mouse Dorsal Lateral Geniculate Nucleus.
Volume: 36
Issue: 19
Pages: 5252-63
•
•
•
•
•
Publication
25988808 | J:233462
   
First Author: Kim T
Year: 2015
Journal: Elife
Title: An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina.
Volume: 4
•
•
•
•
•
Protein
P70662
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
•
•
•
•
•
Protein
D3Z1C5
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
•
•
•
•
•
Publication
38448444 | J:345809
First Author: Rajderkar SS
Year: 2024
Journal: Nat Commun
Title: Dynamic enhancer landscapes in human craniofacial development.
Volume: 15
Issue: 1
Pages: 2030
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•
Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
•
•
•
•
•
Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom