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Search results 1101 to 1200 out of 1328 for Myh6

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Hits by Strain

Type Details Score
Genotype
Symbol: Tg(Myh6-tTA)55Rbns/? Tg(tetO-Bnip3l)1Gwd/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-rtTA)8585Jam/? Tg(tetO-CUGBP1)3413Coop/?
Background: involves: FVB * FVB/N * FVB/NTac
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hprt1/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Gata4/Gata4 Tg(Myh6-Map2k1*)1Jmol/?
Background: involves: 129 * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mir22/Mir22 Tg(Myh6-Ppp3ca)37Eno/?
Background: involves: C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Pln*R9C)#Ces/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(CMV-cat,-ROCK2*)3-1Koba/? Tg(Myh6-cre)1Jmk/?
Background: involves: C57BL/6 * C57BL/6JJcl * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mlip/Mlip Tg(Myh6-Ppp3ca)37Eno/?
Background: involves: C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Pabir1/Pabir1 Myh6/Myh6<+>
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dsp/Dsp Myh6/Myh6<+>
Background: involves: 129 * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pabir1/Pabir1<+> Myh6/Myh6<+>
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Zfpm2)1Sho/? Zfpm2/Zfpm2
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Heineke J
Year: 2010
Journal: Nat Med
Title: CIB1 is a regulator of pathological cardiac hypertrophy.
Volume: 16
Issue: 8
Pages: 872-9
Publication
First Author: Wilkins BJ
Year: 2002
Journal: Mol Cell Biol
Title: Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.
Volume: 22
Issue: 21
Pages: 7603-13
Publication
First Author: Zhang CL
Year: 2002
Journal: Cell
Title: Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy.
Volume: 110
Issue: 4
Pages: 479-88
Publication
First Author: Yang Q
Year: 1999
Journal: Circ Res
Title: In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathy.
Volume: 85
Issue: 9
Pages: 841-7
Publication
First Author: Maillet M
Year: 2009
Journal: J Clin Invest
Title: Cdc42 is an antihypertrophic molecular switch in the mouse heart.
Volume: 119
Issue: 10
Pages: 3079-88
Publication
First Author: Sipione S
Year: 2005
Journal: J Immunol
Title: Impaired cytolytic activity in calreticulin-deficient CTLs.
Volume: 174
Issue: 6
Pages: 3212-9
Publication  
First Author: McLean BA
Year: 2013
Journal: J Mol Cell Cardiol
Title: Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.
Volume: 54
Pages: 9-18
Publication
First Author: Esposito G
Year: 2000
Journal: Am J Physiol Heart Circ Physiol
Title: Cellular and functional defects in a mouse model of heart failure.
Volume: 279
Issue: 6
Pages: H3101-12
Publication
First Author: Heineke J
Year: 2010
Journal: J Mol Cell Cardiol
Title: Calcineurin protects the heart in a murine model of dilated cardiomyopathy.
Volume: 48
Issue: 6
Pages: 1080-7
Publication
First Author: Correll RN
Year: 2017
Journal: Sci Rep
Title: Mitsugumin 29 regulates t-tubule architecture in the failing heart.
Volume: 7
Issue: 1
Pages: 5328
Publication
First Author: Xu J
Year: 2006
Journal: Circ Res
Title: GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation.
Volume: 98
Issue: 3
Pages: 342-50
Publication
First Author: Eden M
Year: 2024
Journal: J Biol Chem
Title: Mst4, a novel cardiac STRIPAK complex-associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy.
Volume: 300
Issue: 5
Pages: 107255
Publication
First Author: Rowe GC
Year: 2014
Journal: Circ Res
Title: PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.
Volume: 115
Issue: 5
Pages: 504-17
Publication
First Author: Dehn S
Year: 2018
Journal: FASEB J
Title: Myeloid receptor CD36 is required for early phagocytosis of myocardial infarcts and induction of Nr4a1-dependent mechanisms of cardiac repair.
Volume: 32
Issue: 1
Pages: 254-264
Publication
First Author: Zhang S
Year: 2019
Journal: Cell Metab
Title: Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair.
Volume: 29
Issue: 2
Pages: 443-456.e5
Publication
First Author: Huang ZP
Year: 2013
Journal: Circ Res
Title: MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress.
Volume: 112
Issue: 9
Pages: 1234-43
Publication  
First Author: Aerni-Flessner L
Year: 2012
Journal: Cardiovasc Diabetol
Title: GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle.
Volume: 11
Pages: 63
Publication
First Author: Oka T
Year: 2006
Journal: Circ Res
Title: Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability.
Volume: 98
Issue: 6
Pages: 837-45
Publication
First Author: Schmitt JP
Year: 2009
Journal: Circulation
Title: Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.
Volume: 119
Issue: 3
Pages: 436-44
Publication  
First Author: Karch J
Year: 2013
Journal: Elife
Title: Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice.
Volume: 2
Pages: e00772
Publication
First Author: Rockman HA
Year: 1998
Journal: J Biol Chem
Title: Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice.
Volume: 273
Issue: 29
Pages: 18180-4
Publication
First Author: Sanna B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.
Volume: 103
Issue: 19
Pages: 7327-32
Publication
First Author: Weeks KL
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K.
Volume: 320
Issue: 4
Pages: H1470-H1485
Publication
First Author: Buerger A
Year: 2006
Journal: J Card Fail
Title: Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.
Volume: 12
Issue: 5
Pages: 392-8
Publication
First Author: Bourajjaj M
Year: 2008
Journal: J Biol Chem
Title: NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.
Volume: 283
Issue: 32
Pages: 22295-303
Publication
First Author: Grimes KM
Year: 2024
Journal: Am J Physiol Heart Circ Physiol
Title: MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network.
Volume: 326
Issue: 1
Pages: H180-H189
Publication
First Author: Lips DJ
Year: 2004
Journal: Circulation
Title: MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.
Volume: 109
Issue: 16
Pages: 1938-41
Publication
First Author: Kuroda J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.
Volume: 107
Issue: 35
Pages: 15565-70
Publication  
First Author: Boikova A
Year: 2022
Journal: Front Cardiovasc Med
Title: HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.
Volume: 9
Pages: 948281
Publication  
First Author: Zhang S
Year: 2015
Journal: J Mol Cell Cardiol
Title: Cardiomyocytes induce macrophage receptor shedding to suppress phagocytosis.
Volume: 87
Pages: 171-9
Publication
First Author: Koch WJ
Year: 1995
Journal: Science
Title: Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
Volume: 268
Issue: 5215
Pages: 1350-3
Publication
First Author: Brinks H
Year: 2010
Journal: Circ Res
Title: Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.
Volume: 107
Issue: 9
Pages: 1140-9
Publication    
First Author: Woodall BP
Year: 2019
Journal: JCI Insight
Title: Alteration of myocardial GRK2 produces a global metabolic phenotype.
Volume: 5
Publication
First Author: Akhter SA
Year: 1999
Journal: Circulation
Title: In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function.
Volume: 100
Issue: 6
Pages: 648-53
Publication
First Author: Chen M
Year: 2013
Journal: Circ Res
Title: Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.
Volume: 112
Issue: 8
Pages: 1121-34
Publication
First Author: Eckhart AD
Year: 2002
Journal: J Mol Cell Cardiol
Title: Inhibition of betaARK1 restores impaired biochemical beta-adrenergic receptor responsiveness but does not rescue CREB(A133) induced cardiomyopathy.
Volume: 34
Issue: 6
Pages: 669-77
Strain
Attribute String: mutant strain, transgenic, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Xiong D
Year: 2010
Journal: J Mol Cell Cardiol
Title: Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice.
Volume: 48
Issue: 1
Pages: 211-9
Publication
First Author: Dalal S
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Osteopontin stimulates apoptosis in adult cardiac myocytes via the involvement of CD44 receptors, mitochondrial death pathway, and endoplasmic reticulum stress.
Volume: 306
Issue: 8
Pages: H1182-91
Publication
First Author: McCloskey DT
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy.
Volume: 294
Issue: 1
Pages: H205-12
Publication
First Author: Redfern CH
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.
Volume: 97
Issue: 9
Pages: 4826-31
Publication  
First Author: Sala V
Year: 2016
Journal: Biomed Res Int
Title: A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart.
Volume: 2016
Pages: 9549036
Publication
First Author: Redfern CH
Year: 1999
Journal: Nat Biotechnol
Title: Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice.
Volume: 17
Issue: 2
Pages: 165-9
Publication
First Author: Baker AJ
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Abnormal contraction caused by expression of G(i)-coupled receptor in transgenic model of dilated cardiomyopathy.
Volume: 280
Issue: 4
Pages: H1653-9
Publication
First Author: Weidenfeld-Baranboim K
Year: 2009
Journal: Nucleic Acids Res
Title: The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3.
Volume: 37
Issue: 7
Pages: 2194-203
Publication
First Author: Mungrue IN
Year: 2002
Journal: J Clin Invest
Title: Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death.
Volume: 109
Issue: 6
Pages: 735-43
Publication
First Author: Mueller EE
Year: 2011
Journal: Cardiovasc Res
Title: Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy.
Volume: 89
Issue: 3
Pages: 623-33
Publication
First Author: Renault MA
Year: 2010
Journal: Circ Heart Fail
Title: Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy.
Volume: 3
Issue: 3
Pages: 431-9
Publication
First Author: Ainscough JF
Year: 2009
Journal: Cardiovasc Res
Title: Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction.
Volume: 81
Issue: 3
Pages: 592-600
Publication
First Author: Vigneron F
Year: 2011
Journal: Cardiovasc Res
Title: GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways.
Volume: 90
Issue: 1
Pages: 49-56
Publication
First Author: Yang LL
Year: 2004
Journal: Circulation
Title: Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice.
Volume: 109
Issue: 2
Pages: 255-61
Publication  
First Author: Wang X
Year: 2024
Journal: JCI Insight
Title: Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury.
Volume: 9
Issue: 5
Publication
First Author: Pawlinski R
Year: 2007
Journal: Circulation
Title: Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy.
Volume: 116
Issue: 20
Pages: 2298-306
Publication
First Author: Mahmoud AI
Year: 2013
Journal: Nature
Title: Meis1 regulates postnatal cardiomyocyte cell cycle arrest.
Volume: 497
Issue: 7448
Pages: 249-253
Publication
First Author: Raso A
Year: 2021
Journal: Nat Commun
Title: A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration.
Volume: 12
Issue: 1
Pages: 4808
Publication
First Author: Lim HW
Year: 2000
Journal: J Mol Cell Cardiol
Title: Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition.
Volume: 32
Issue: 4
Pages: 697-709
Publication
First Author: Seok HY
Year: 2014
Journal: Circ Res
Title: Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy.
Volume: 114
Issue: 10
Pages: 1585-95
Publication
First Author: Shioi T
Year: 2000
Journal: EMBO J
Title: The conserved phosphoinositide 3-kinase pathway determines heart size in mice.
Volume: 19
Issue: 11
Pages: 2537-48
Publication
First Author: Rigor DL
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.
Volume: 296
Issue: 3
Pages: H566-72
Publication
First Author: Ritchie RH
Year: 2012
Journal: Diabetologia
Title: Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes.
Volume: 55
Issue: 12
Pages: 3369-81
Publication
First Author: Cooley N
Year: 2013
Journal: Circ Heart Fail
Title: No contribution of IP3-R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy.
Volume: 6
Issue: 2
Pages: 318-25
Publication
First Author: He L
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.
Volume: 310
Issue: 11
Pages: H1520-32
Publication
First Author: Diwan A
Year: 2007
Journal: J Clin Invest
Title: Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice.
Volume: 117
Issue: 10
Pages: 2825-33
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Collins HE
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Novel role of the ER/SR Ca2+ sensor STIM1 in the regulation of cardiac metabolism.
Volume: 316
Issue: 5
Pages: H1014-H1026
Publication
First Author: Collins HE
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function.
Volume: 306
Issue: 8
Pages: H1231-9
Publication
First Author: Ozcan M
Year: 2023
Journal: Cell Metab
Title: Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Volume: 35
Issue: 6
Pages: 928-942.e4
Publication
First Author: Trivedi PC
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.
Volume: 1866
Issue: 10
Pages: 165832
Publication
First Author: Wang H
Year: 2019
Journal: Biochem Biophys Res Commun
Title: NLRP3 inhibition improves heart function in GPER knockout mice.
Volume: 514
Issue: 3
Pages: 998-1003
Publication
First Author: Memo M
Year: 2013
Journal: Cardiovasc Res
Title: Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
Volume: 99
Issue: 1
Pages: 65-73
Publication
First Author: Ward AJ
Year: 2010
Journal: Hum Mol Genet
Title: CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.
Volume: 19
Issue: 18
Pages: 3614-22
Publication
First Author: Heitmeier MR
Year: 2018
Journal: Sci Rep
Title: Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia.
Volume: 8
Issue: 1
Pages: 6475
Publication
First Author: Yang Q
Year: 1998
Journal: J Clin Invest
Title: A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy.
Volume: 102
Issue: 7
Pages: 1292-300
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: transgene insertion 97, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Yang Q
Year: 2001
Journal: Cardiovasc Res
Title: PKA-dependent phosphorylation of cardiac myosin binding protein C in transgenic mice.
Volume: 51
Issue: 1
Pages: 80-8
Allele
Name: transgene insertion, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 7, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 27, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion alpha-3, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Reporter
Publication
First Author: Xie C
Year: 2016
Journal: Cell Res
Title: Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome.
Volume: 26
Issue: 10
Pages: 1099-1111
Publication
First Author: Habets PE
Year: 2003
Journal: J Muscle Res Cell Motil
Title: Cardiac expression of Gal4 causes cardiomyopathy in a dose-dependent manner.
Volume: 24
Issue: 2-3
Pages: 205-9
Genotype
Symbol: Csrp3/Csrp3 Tg(Myh6-ADRBK1)27Wjk/?
Background: involves: C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hdac5/Hdac5 Tg(Myh6-Ppp3ca)37Eno/?
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Pik3ca)1Siz/? Tg(Myh6-Pik3r1/PIK3CA)BSiz/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hdac9/Hdac9 Tg(Myh6-Ppp3ca)37Eno/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity: cx
Has Mutant Allele: true