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Search results 1101 to 1179 out of 1179 for Neurog3

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0.031s
Type Details Score
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: endocrine pancreas
Notes: endocrine progenitors sorted using Neurog3 EGFP+ reporter gene expression
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: endocrine pancreas
Notes: endocrine progenitors sorted using Neurog3 EGFP+ reporter gene expression
Curation Status: Curated
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-03-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6119679
Age: embryonic day 14.5
Image: 3A top right
Note: Some S-Gal stained cells also expressed Neurog3 (endocrine progenitor) cells.
Specimen Label: 3A top right
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7718615
Assay Type: RNA in situ
Annotation Date: 2024-09-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7718628
Age: embryonic day 14.5
Note: Expression throughout pancreatic epithelium. Expression co-localized with Neurog3 expression.
Specimen Label: 5C
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7853888
Assay Type: RNA in situ
Annotation Date: 2025-01-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3565022
Stage: TS22
Assay Id: MGI:7852795
Age: embryonic day 14.5
Note: Expression did not overlap with Neurog3 staining in the trunk.
Specimen Label: 2D
Detected: false
Specimen Num: 2
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
GXD Expression
Probe: MGI:5448181
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5448231
Age: embryonic day 15.5
Image: 5G/I
Note: Expression in some Neurog3-expressing endocrine cell precursors. Authors report that the frequency of Hnf4a and Neurog3 co-expressing cells decreased as development proceeded.
Specimen Label: 5G/I
Detected: true
Specimen Num: 9
Allele
Name: transgene insertion 1, Helena Edlund
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: neurogenin 3; targeted mutation 3.1, Guoqiang Gu
Allele Type: Targeted
Attribute String: Recombinase
Genotype
Symbol: Tg(Pdx1-Neurog3)1Heed/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
GXD Expression  
Probe: MGI:7853888
Assay Type: RNA in situ
Annotation Date: 2025-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7852795
Age: embryonic day 12.5
Note: Expression was detected in the newly formed branches of the dorsal pancreas at E12.5. Expression was downregulated in the 'cleft' region between future branches. Expression did not overlap with Neurog3 staining in the trunk.
Specimen Label: 2H
Detected: true
Specimen Num: 4
Allele
Name: transgene insertion 1, Douglas A Melton
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: neurogenin 3; targeted mutation 1.1, Guoqiang Gu
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Allele
Name: transgene insertion, Guoqiang Gu
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion, Guoqiang Gu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7510116
Age: embryonic day 15.5
Image: 5A/B/C
Note: Expressed at lower levels in the cells lining the lumen of the epithelial chords, while high level cells were detected within or adjacent to the epithelial chords. There was a statistically significant correlation between Neurog3 and Foxa2 expression levels (see Fig 5D and 5E).
Specimen Label: 5A/B/C
Detected: true
Specimen Num: 1
Strain
Attribute String: transgenic, mutant stock
Allele
Name: neurogenin 3; targeted mutation 1, Guoqiang Gu
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Recombinase
Genotype
Symbol: Neurog3/Neurog3<+>
Background: involves: 129S6/SvEvTac
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Allele
Name: transgene insertion 1, Michael S German
Allele Type: Transgenic
Attribute String: Reporter
Genotype
Symbol: Neurog3/Neurog3 Tg(Pdx1-cre/Esr1*)1Mga/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Clayton HW
Year: 2016
Journal: Cell Rep
Title: Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.
Volume: 17
Issue: 8
Pages: 2028-2041
HT Experiment
Series Id: E-GEOD-53214
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Courty E
Year: 2019
Journal: Diabetes
Title: Adaptive β-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance.
Volume: 68
Issue: 1
Pages: 95-108
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Axel Behrens
Allele Type: Targeted
Attribute String: Conditional ready
Genotype
Symbol: Neurog3/Neurog3<+> Pdx1/Pdx1<+> Tg(tetO-Myt1)2Ggu/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Neurog3/Neurog3 Tg(Ins2-cre)25Mgn/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Neurog3/Neurog3
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Neurog3/Neurog3 Tg(Pdx1-cre/Esr1*)1Mga/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dicer1/Dicer1 Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Jin C
Year: 2017
Journal: Reproduction
Title: EZH2 deletion promotes spermatogonial differentiation and apoptosis.
Volume: 154
Issue: 5
Pages: 615-625
Publication  
First Author: Lorberbaum DS
Year: 2020
Journal: Development
Title: Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification.
Volume: 147
Issue: 12
Publication
First Author: van Arensbergen J
Year: 2017
Journal: PLoS One
Title: A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.
Volume: 12
Issue: 2
Pages: e0171508
Publication
First Author: Duvall E
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development.
Volume: 119
Issue: 26
Pages: e2201267119
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Ben-Othman N
Year: 2017
Journal: Cell
Title: Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.
Volume: 168
Issue: 1-2
Pages: 73-85.e11
Publication
First Author: Al-Hasani K
Year: 2013
Journal: Dev Cell
Title: Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.
Volume: 26
Issue: 1
Pages: 86-100
Publication
First Author: Nakagawa T
Year: 2010
Journal: Science
Title: Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment.
Volume: 328
Issue: 5974
Pages: 62-7
Genotype
Symbol: Neurog3/Neurog3 Tg(Ins2-cre)25Mgn/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-EGFP)39Miya/? Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: C57BL/6 * CBA * DBA/2NJcl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Lu N
Year: 2013
Journal: Endocrinology
Title: Loss of vascular endothelial growth factor A (VEGFA) isoforms in the testes of male mice causes subfertility, reduces sperm numbers, and alters expression of genes that regulate undifferentiated spermatogonia.
Volume: 154
Issue: 12
Pages: 4790-802
Publication
First Author: Ediger BN
Year: 2017
Journal: J Clin Invest
Title: LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Volume: 127
Issue: 1
Pages: 215-229
Publication
First Author: Bjerknes M
Year: 2010
Journal: Dev Biol
Title: Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium.
Volume: 345
Issue: 1
Pages: 49-63
Publication
First Author: Huang Z
Year: 2013
Journal: PLoS One
Title: NOTCH1 gain of function in germ cells causes failure of spermatogenesis in male mice.
Volume: 8
Issue: 7
Pages: e71213
Publication
First Author: Yoshida S
Year: 2006
Journal: Development
Title: The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage.
Volume: 133
Issue: 8
Pages: 1495-505
Publication
First Author: Sasaki S
Year: 2015
Journal: Diabetologia
Title: Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice.
Volume: 58
Issue: 11
Pages: 2582-91
Publication
First Author: Zhang W
Year: 2006
Journal: Cell Metab
Title: PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Volume: 4
Issue: 6
Pages: 491-7
Publication
First Author: Ikami K
Year: 2015
Journal: Development
Title: Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis.
Volume: 142
Issue: 9
Pages: 1582-92
Publication
First Author: Chen YJ
Year: 2014
Journal: Cell Rep
Title: De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts.
Volume: 6
Issue: 6
Pages: 1046-1058
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Sancho R
Year: 2014
Journal: Cell Stem Cell
Title: Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.
Volume: 15
Issue: 2
Pages: 139-53
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Pdx1-cre)6Tuv/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Pdx1-cre)6Tuv
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/? Krt19/?
Background: B6.Cg-Gt(ROSA)26Sor Krt19
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Li HJ
Year: 2014
Journal: Gastroenterology
Title: Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus.
Volume: 146
Issue: 3
Pages: 754-764.e3
Publication
First Author: Walker NM
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Goblet cell hyperplasia is not epithelial-autonomous in the Cftr knockout intestine.
Volume: 322
Issue: 2
Pages: G282-G293
Publication
First Author: Klein AM
Year: 2010
Journal: Cell Stem Cell
Title: Mouse germ line stem cells undergo rapid and stochastic turnover.
Volume: 7
Issue: 2
Pages: 214-24
Publication
First Author: Sznurkowska MK
Year: 2020
Journal: Nat Commun
Title: Tracing the cellular basis of islet specification in mouse pancreas.
Volume: 11
Issue: 1
Pages: 5037
Publication
First Author: Nyabi O
Year: 2009
Journal: Nucleic Acids Res
Title: Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells.
Volume: 37
Issue: 7
Pages: e55