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Search results 1101 to 1200 out of 5729 for Nlrp3

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Type Details Score
Publication
24827856 | J:217355
First Author: Kupz A
Year: 2014
Journal: PLoS One
Title: In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.
Volume: 9
Issue: 5
Pages: e97418
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Publication
34471287 | J:361095
First Author: Lee S
Year: 2021
Journal: Nature
Title: AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Volume: 597
Issue: 7876
Pages: 415-419
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Publication
35139355 | J:324833
First Author: Simpson DS
Year: 2022
Journal: Immunity
Title: Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Volume: 55
Issue: 3
Pages: 423-441.e9
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Publication
29576451 | J:262477
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
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Publication
38409108 | J:361094
First Author: Han JH
Year: 2024
Journal: Nat Commun
Title: NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
Volume: 15
Issue: 1
Pages: 1739
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Publication
27339979 | J:233302
First Author: Birchenough GM
Year: 2016
Journal: Science
Title: A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.
Volume: 352
Issue: 6293
Pages: 1535-42
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Publication
21464320 | J:171365
First Author: Mankan AK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.
Volume: 108
Issue: 16
Pages: 6567-72
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Publication
26008898 | J:224778
First Author: Kim ML
Year: 2015
Journal: J Exp Med
Title: Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Volume: 212
Issue: 6
Pages: 927-38
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Publication
23995233 | J:208219
First Author: Freigang S
Year: 2013
Journal: Nat Immunol
Title: Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis.
Volume: 14
Issue: 10
Pages: 1045-53
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Publication
25166912 | J:248542
First Author: Sahoo M
Year: 2014
Journal: PLoS Pathog
Title: Neutrophil elastase causes tissue damage that decreases host tolerance to lung infection with burkholderia species.
Volume: 10
Issue: 8
Pages: e1004327
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Publication
31169521 | J:295265
First Author: Miyabe C
Year: 2019
Journal: J Clin Invest
Title: Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.
Volume: 129
Issue: 9
Pages: 3610-3624
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Publication
22840842 | J:187388
First Author: Vladimer GI
Year: 2012
Journal: Immunity
Title: The NLRP12 inflammasome recognizes Yersinia pestis.
Volume: 37
Issue: 1
Pages: 96-107
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Publication
30510167 | J:287363
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
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Publication
30021146 | J:289210
First Author: Mandal P
Year: 2018
Journal: Immunity
Title: Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Volume: 49
Issue: 1
Pages: 42-55.e6
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Publication
22365665 | J:181625
First Author: Vince JE
Year: 2012
Journal: Immunity
Title: Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Volume: 36
Issue: 2
Pages: 215-27
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Publication
28002730 | J:291647
First Author: Kuroda E
Year: 2016
Journal: Immunity
Title: Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.
Volume: 45
Issue: 6
Pages: 1299-1310
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Publication
20668698 | J:163082
First Author: Koh YS
Year: 2010
Journal: PLoS One
Title: MyD88-dependent signaling contributes to host defense against ehrlichial infection.
Volume: 5
Issue: 7
Pages: e11758
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Publication
27509078 | J:236919
First Author: Mohammadi N
Year: 2016
Journal: PLoS One
Title: Neutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection.
Volume: 11
Issue: 8
Pages: e0160249
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Publication
34188052 | J:307825
First Author: Fisher AL
Year: 2021
Journal: Nat Commun
Title: Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy.
Volume: 12
Issue: 1
Pages: 4026
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Publication
28096401 | J:240745
First Author: Hardbower DM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Volume: 114
Issue: 5
Pages: E751-E760
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Publication
28923684 | J:252121
First Author: McCoy AM
Year: 2017
Journal: Am J Pathol
Title: IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis.
Volume: 187
Issue: 12
Pages: 2635-2644
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Publication
29596938 | J:309497
First Author: Piao X
Year: 2019
Journal: J Allergy Clin Immunol
Title: Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation.
Volume: 143
Issue: 1
Pages: 213-228.e10
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Pathway
R-MMU-844456 | The NLRP3 inflammasome
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HT Experiment
E-GEOD-43034 | Canonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline
Series Id: GSE43034
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Interaction Experiment
Xu T (2022)
Description: Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation.
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Interaction Experiment
Lin Y (2022)
Description: TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
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Publication
33691097 | J:334258
First Author: Bambouskova M
Year: 2021
Journal: Cell Rep
Title: Itaconate confers tolerance to late NLRP3 inflammasome activation.
Volume: 34
Issue: 10
Pages: 108756
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Publication
35353387 | J:325990
First Author: Drinkall S
Year: 2022
Journal: Glia
Title: The two pore potassium channel THIK-1 regulates NLRP3 inflammasome activation.
Volume: 70
Issue: 7
Pages: 1301-1316
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Publication
22819539 | J:187890
First Author: Rathinam VA
Year: 2012
Journal: Cell
Title: TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
Volume: 150
Issue: 3
Pages: 606-19
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Publication
22984082 | J:190649
First Author: Bauernfeind F
Year: 2012
Journal: J Immunol
Title: NLRP3 inflammasome activity is negatively controlled by miR-223.
Volume: 189
Issue: 8
Pages: 4175-81
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Publication
28031477 | J:240100
First Author: Lordén G
Year: 2017
Journal: J Exp Med
Title: Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation.
Volume: 214
Issue: 2
Pages: 511-528
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Publication
30206651 | J:279535
First Author: Perera AP
Year: 2018
Journal: Mamm Genome
Title: NLRP3 inflammasome in colitis and colitis-associated colorectal cancer.
Volume: 29
Issue: 11-12
Pages: 817-830
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Publication
31577945 | J:288383
First Author: Hughes MM
Year: 2019
Journal: Cell Rep
Title: Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Volume: 29
Issue: 1
Pages: 151-161.e5
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Publication
29855523 | J:323710
First Author: Rodrigue-Gervais IG
Year: 2018
Journal: Sci Rep
Title: The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes.
Volume: 8
Issue: 1
Pages: 8446
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Publication
33893171 | J:307959
First Author: Ni J
Year: 2021
Journal: J Immunol
Title: Ubc13 Promotes K63-Linked Polyubiquitination of NLRP3 to Activate Inflammasome.
Volume: 206
Issue: 10
Pages: 2376-2385
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Publication
36443515 | J:337689
First Author: Zhang Z
Year: 2023
Journal: Nat Immunol
Title: Distinct changes in endosomal composition promote NLRP3 inflammasome activation.
Volume: 24
Issue: 1
Pages: 30-41
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Publication
35294888 | J:324902
First Author: Joshi H
Year: 2022
Journal: Cell Rep
Title: L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis.
Volume: 38
Issue: 11
Pages: 110507
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Publication
36763010 | J:354780
First Author: Rodrigues TS
Year: 2023
Journal: J Infect Dis
Title: CASP4/11 Contributes to NLRP3 Activation and COVID-19 Exacerbation.
Volume: 227
Issue: 12
Pages: 1364-1375
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Publication
34342641 | J:321627
 
First Author: Li S
Year: 2021
Journal: J Exp Med
Title: ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation.
Volume: 218
Issue: 9
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Publication
25800347 | J:221869
 
First Author: Ives A
Year: 2015
Journal: Nat Commun
Title: Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.
Volume: 6
Pages: 6555
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Publication
25816776 | J:346258
First Author: Chakrabarti A
Year: 2015
Journal: Cell Host Microbe
Title: RNase L activates the NLRP3 inflammasome during viral infections.
Volume: 17
Issue: 4
Pages: 466-77
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Publication
37359517 | J:346950
 
First Author: Hou Y
Year: 2023
Journal: Front Immunol
Title: Apilimod activates the NLRP3 inflammasome through lysosome-mediated mitochondrial damage.
Volume: 14
Pages: 1128700
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Publication
31836654 | J:289587
First Author: Bhatta A
Year: 2020
Journal: J Immunol
Title: A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome.
Volume: 204
Issue: 2
Pages: 428-437
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Publication
31263038 | J:278496
First Author: Liu W
Year: 2019
Journal: J Immunol
Title: Tim-4 Inhibits NLRP3 Inflammasome via the LKB1/AMPKα Pathway in Macrophages.
Volume: 203
Issue: 4
Pages: 990-1000
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Publication
28729463 | J:245617
First Author: Shen L
Year: 2017
Journal: J Lipid Res
Title: Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy.
Volume: 58
Issue: 9
Pages: 1808-1821
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Publication
21940680 | J:179453
First Author: Xiang M
Year: 2011
Journal: J Immunol
Title: Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells.
Volume: 187
Issue: 9
Pages: 4809-17
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Publication
20962258 | J:166055
First Author: Shigeoka AA
Year: 2010
Journal: J Immunol
Title: An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.
Volume: 185
Issue: 10
Pages: 6277-85
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Publication
39686706 | J:360135
First Author: O'Siorain JR
Year: 2024
Journal: FASEB J
Title: Time-of-day control of mitochondria regulates NLRP3 inflammasome activation in macrophages.
Volume: 38
Issue: 24
Pages: e70235
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Publication
24270411 | J:229062
First Author: Wu YH
Year: 2014
Journal: Cell Death Differ
Title: Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.
Volume: 21
Issue: 3
Pages: 451-61
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Publication
30874540 | J:287947
First Author: Martine P
Year: 2019
Journal: Cell Death Dis
Title: HSP70 is a negative regulator of NLRP3 inflammasome activation.
Volume: 10
Issue: 4
Pages: 256
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Publication
29277324 | J:262161
First Author: Liu P
Year: 2018
Journal: Biochim Biophys Acta
Title: Sirtuin 3-induced macrophage autophagy in regulating NLRP3 inflammasome activation.
Volume: 1864
Issue: 3
Pages: 764-777
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Publication
39405939 | J:358459
First Author: Huang W
Year: 2024
Journal: Int Immunopharmacol
Title: Ulinastatin attenuates renal ischemia-reperfusion injury by inhibiting NLRP3 inflammasome-triggered pyroptosis.
Volume: 143
Issue: Pt 1
Pages: 113306
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Publication
27455510 | J:240118
First Author: Moon JS
Year: 2016
Journal: Nat Med
Title: NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages.
Volume: 22
Issue: 9
Pages: 1002-12
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Publication
37283747 | J:346927
 
First Author: Bierschenk D
Year: 2023
Journal: Front Immunol
Title: C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation.
Volume: 14
Pages: 1149822
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Publication
31026586 | J:295527
 
First Author: Qin M
Year: 2019
Journal: Free Radic Biol Med
Title: Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Volume: 137
Pages: 99-109
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Publication
39179640 | J:359293
First Author: Lee J
Year: 2024
Journal: Cell Death Differ
Title: Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation.
Volume: 31
Issue: 12
Pages: 1679-1694
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Publication
26848562 | J:301845
First Author: Qiao C
Year: 2016
Journal: CNS Neurosci Ther
Title: Atp13a2 Deficiency Aggravates Astrocyte-Mediated Neuroinflammation via NLRP3 Inflammasome Activation.
Volume: 22
Issue: 6
Pages: 451-60
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Publication
35126159 | J:328471
 
First Author: Dong W
Year: 2022
Journal: Front Pharmacol
Title: Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome.
Volume: 13
Pages: 783706
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Publication
25574840 | J:220392
First Author: Moon JS
Year: 2015
Journal: J Clin Invest
Title: UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.
Volume: 125
Issue: 2
Pages: 665-80
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Publication
23427251 | J:194524
First Author: Zhang Z
Year: 2013
Journal: J Immunol
Title: Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses.
Volume: 190
Issue: 7
Pages: 3517-24
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Publication
34907173 | J:321654
First Author: Zhang Y
Year: 2021
Journal: Cell Death Dis
Title: TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia.
Volume: 12
Issue: 12
Pages: 1159
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Publication
31092335 | J:290357
First Author: Wang H
Year: 2019
Journal: Biochem Biophys Res Commun
Title: NLRP3 inhibition improves heart function in GPER knockout mice.
Volume: 514
Issue: 3
Pages: 998-1003
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Publication
31318658 | J:294958
First Author: Zhuang T
Year: 2019
Journal: Circ Res
Title: Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation.
Volume: 125
Issue: 6
Pages: 590-605
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Publication
36640341 | J:332901
First Author: Meyers AK
Year: 2023
Journal: Cell Rep
Title: Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation.
Volume: 42
Issue: 1
Pages: 111941
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Publication
37001519 | J:334741
First Author: Zhu F
Year: 2023
Journal: Immunity
Title: The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.
Volume: 56
Issue: 4
Pages: 753-767.e8
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Publication
30902848 | J:272519
     
First Author: Chen KW
Year: 2019
Journal: EMBO J
Title: Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
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Protein Coding Gene
MGI:1859396 | Mefv
Type: protein_coding_gene
Organism: mouse, laboratory
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Interaction Experiment
Qin Y (2021)
Description: TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
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Interaction Experiment
Niu T (2021)
Description: NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.
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