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Search results 1101 to 1200 out of 1843 for Pomc

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Type Details Score
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Órdenes P
Year: 2021
Journal: Sci Rep
Title: Lactate activates hypothalamic POMC neurons by intercellular signaling.
Volume: 11
Issue: 1
Pages: 21644
Publication
First Author: Guan X
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility.
Volume: 303
Issue: 7
Pages: E853-64
Publication      
First Author: Friedman JM
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of an rtTA transgene controlled by the Pomc promoter
Publication
First Author: Vong L
Year: 2011
Journal: Neuron
Title: Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons.
Volume: 71
Issue: 1
Pages: 142-54
Publication    
First Author: Dodd GT
Year: 2018
Journal: Elife
Title: Insulin regulates POMC neuronal plasticity to control glucose metabolism.
Volume: 7
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: cells expressing Pomc
Curation Status: Curated
Publication
First Author: Yoon NA
Year: 2022
Journal: Cell Rep
Title: UCP2-dependent redox sensing in POMC neurons regulates feeding.
Volume: 41
Issue: 13
Pages: 111894
Publication
First Author: Kim GH
Year: 2018
Journal: J Clin Invest
Title: Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
Volume: 128
Issue: 3
Pages: 1125-1140
Publication  
First Author: Yi CX
Year: 2017
Journal: Nat Commun
Title: TNFα drives mitochondrial stress in POMC neurons in obesity.
Volume: 8
Pages: 15143
Protein
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
Publication
First Author: Cowley MA
Year: 2001
Journal: Nature
Title: Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus.
Volume: 411
Issue: 6836
Pages: 480-4
Publication
First Author: Kang GM
Year: 2021
Journal: Cell Metab
Title: Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism.
Volume: 33
Issue: 2
Pages: 334-349.e6
Publication
First Author: Gao Y
Year: 2017
Journal: Cell Rep
Title: TrpC5 Mediates Acute Leptin and Serotonin Effects via Pomc Neurons.
Volume: 18
Issue: 3
Pages: 583-592
Publication  
First Author: He Z
Year: 2021
Journal: JCI Insight
Title: PERK in POMC neurons connects celastrol with metabolism.
Volume: 6
Issue: 18
Publication
First Author: Varela L
Year: 2017
Journal: Diabetes
Title: Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons.
Volume: 66
Issue: 6
Pages: 1511-1520
Publication
First Author: Kaushik S
Year: 2012
Journal: EMBO Rep
Title: Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
Volume: 13
Issue: 3
Pages: 258-65
Publication
First Author: Silva JP
Year: 2016
Journal: Genome Med
Title: Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring.
Volume: 8
Issue: 1
Pages: 93
Publication    
First Author: Paeger L
Year: 2017
Journal: Elife
Title: Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.
Volume: 6
Publication
First Author: Cui J
Year: 2016
Journal: J Clin Invest
Title: Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.
Volume: 126
Issue: 9
Pages: 3192-206
Publication
First Author: Liu Z
Year: 2018
Journal: FEBS Lett
Title: Short-term tamoxifen treatment has long-term effects on metabolism in high-fat diet-fed mice with involvement of Nmnat2 in POMC neurons.
Volume: 592
Issue: 19
Pages: 3305-3316
Publication
First Author: Tang Q
Year: 2022
Journal: Diabetes
Title: MANF in POMC Neurons Promotes Brown Adipose Tissue Thermogenesis and Protects Against Diet-Induced Obesity.
Volume: 71
Issue: 11
Pages: 2344-2359
Publication
First Author: Mun SH
Year: 2023
Journal: Cell Rep
Title: Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Volume: 42
Issue: 7
Pages: 112746
Publication  
First Author: Perissinotti PP
Year: 2021
Journal: Front Neurosci
Title: Genetic Deletion of KLHL1 Leads to Hyperexcitability in Hypothalamic POMC Neurons and Lack of Electrical Responses to Leptin.
Volume: 15
Pages: 718464
Publication  
First Author: Yuan F
Year: 2020
Journal: Mol Metab
Title: Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling.
Volume: 42
Pages: 101084
Publication
First Author: Coester B
Year: 2020
Journal: Diabetes
Title: Amylin/Calcitonin Receptor-Mediated Signaling in POMC Neurons Influences Energy Balance and Locomotor Activity in Chow-Fed Male Mice.
Volume: 69
Issue: 6
Pages: 1110-1125
Publication
First Author: Boston BA
Year: 1997
Journal: Science
Title: Independent and additive effects of central POMC and leptin pathways on murine obesity.
Volume: 278
Issue: 5343
Pages: 1641-4
Publication
First Author: Yang SB
Year: 2012
Journal: Neuron
Title: Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons.
Volume: 75
Issue: 3
Pages: 425-36
Publication
First Author: Dorfman MD
Year: 2017
Journal: Diabetes
Title: Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.
Volume: 66
Issue: 4
Pages: 920-934
Publication
First Author: Yang Y
Year: 2019
Journal: Nat Commun
Title: Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis.
Volume: 10
Issue: 1
Pages: 1718
Publication
First Author: Mercer AJ
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice.
Volume: 306
Issue: 8
Pages: E904-15
Publication
First Author: Timper K
Year: 2018
Journal: Cell Rep
Title: Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity.
Volume: 25
Issue: 2
Pages: 383-397.e10
Publication
First Author: Lutz TA
Year: 2018
Journal: Diabetes
Title: Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus.
Volume: 67
Issue: 5
Pages: 805-817
Publication
First Author: Yao T
Year: 2017
Journal: Diabetes
Title: Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia.
Volume: 66
Issue: 3
Pages: 663-673
Publication
First Author: Maejima Y
Year: 2014
Journal: FEBS Lett
Title: Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus.
Volume: 588
Issue: 23
Pages: 4404-12
Publication
First Author: Lin S
Year: 2000
Journal: Brain Res
Title: Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain.
Volume: 875
Issue: 1-2
Pages: 89-95
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: ribosome pulldown from cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: ribosome pulldown from cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: ribosome pulldown from cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 12
Stage: 28
Structure . Name: hypothalamus
Notes: ribosome pulldown from cells expressing Pomc
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 51
Stage: 28
Structure . Name: arcuate nucleus
Notes: sorted POMC neuron from a fed mouse
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 51
Stage: 28
Structure . Name: arcuate nucleus
Notes: sorted POMC neuron from a fed mouse
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 55
Stage: 28
Structure . Name: arcuate nucleus
Notes: sorted POMC neuron from a fed mouse
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 56
Stage: 28
Structure . Name: arcuate nucleus
Notes: sorted POMC neuron from a fed mouse
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 55
Stage: 28
Structure . Name: arcuate nucleus
Notes: sorted POMC neuron from a fed mouse
Curation Status: Curated
Publication
First Author: Lin HV
Year: 2010
Journal: Diabetes
Title: Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons.
Volume: 59
Issue: 2
Pages: 337-46
Publication
First Author: Smith MA
Year: 2015
Journal: Cell Rep
Title: Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice.
Volume: 11
Issue: 3
Pages: 335-43
Publication
First Author: Ramírez S
Year: 2017
Journal: Cell Metab
Title: Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.
Volume: 25
Issue: 6
Pages: 1390-1399.e6
Publication
First Author: Schneeberger M
Year: 2013
Journal: Cell
Title: Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Volume: 155
Issue: 1
Pages: 172-87
Publication
First Author: Gómez-Valadés AG
Year: 2021
Journal: Cell Metab
Title: Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis.
Volume: 33
Issue: 9
Pages: 1820-1835.e9
Publication
First Author: Williams KW
Year: 2014
Journal: Cell Metab
Title: Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.
Volume: 20
Issue: 3
Pages: 471-82
Publication
First Author: Mounien L
Year: 2010
Journal: FASEB J
Title: Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons.
Volume: 24
Issue: 6
Pages: 1747-58
Publication
First Author: Zhang H
Year: 2011
Journal: PLoS Biol
Title: Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.
Volume: 9
Issue: 7
Pages: e1001112
Publication
First Author: Claret M
Year: 2007
Journal: J Clin Invest
Title: AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
Volume: 117
Issue: 8
Pages: 2325-36
Publication    
First Author: Mandelblat-Cerf Y
Year: 2015
Journal: Elife
Title: Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales.
Volume: 4
Publication  
First Author: Tang M
Year: 2023
Journal: Mol Metab
Title: GPSM1 in POMC neurons impairs brown adipose tissue thermogenesis and provokes diet-induced obesity.
Volume: 79
Pages: 101839
Publication
First Author: Al-Massadi O
Year: 2019
Journal: Diabetes
Title: MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Volume: 68
Issue: 12
Pages: 2210-2222
Publication
First Author: Dodd GT
Year: 2015
Journal: Cell
Title: Leptin and insulin act on POMC neurons to promote the browning of white fat.
Volume: 160
Issue: 1-2
Pages: 88-104
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Publication
First Author: Al-Qassab H
Year: 2009
Journal: Cell Metab
Title: Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Volume: 10
Issue: 5
Pages: 343-54
Publication
First Author: Marenne G
Year: 2020
Journal: Cell Metab
Title: Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription.
Volume: 31
Issue: 6
Pages: 1107-1119.e12
Publication
First Author: Keilhoff G
Year: 2001
Journal: Acta Histochem
Title: Lack of neuronal NOS has consequences for the expression of POMC and POMC-derived peptides in the mouse pituitary.
Volume: 103
Issue: 4
Pages: 397-412
Publication
First Author: Newton AJ
Year: 2013
Journal: Endocrinology
Title: AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice.
Volume: 154
Issue: 1
Pages: 172-83
Publication  
First Author: He Z
Year: 2019
Journal: Mol Metab
Title: Direct and indirect effects of liraglutide on hypothalamic POMC and NPY/AgRP neurons - Implications for energy balance and glucose control.
Volume: 28
Pages: 120-134
Publication  
First Author: Smith ME
Year: 1994
Journal: J Neurol Sci
Title: POMC neuropeptides and their receptors in the neuromuscular system of wobbler mice.
Volume: 124 Suppl
Pages: 56-8
Publication
First Author: Ancans J
Year: 1999
Journal: J Invest Dermatol
Title: Human epidermal proopiomelanocortin (POMC) cDNA variant is identical to mouse POMC cDNA.
Volume: 112
Issue: 4
Pages: 516-7
Publication
First Author: Farooqui J
Year: 1999
Journal: J Invest Dermatol
Title: Human epidermal proopiomelanocortin (POMC) cDNA variant is identical to mouse POMC cDNA - Reply.
Volume: 112
Issue: 4
Pages: 517
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: do Carmo JM
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation.
Volume: 307
Issue: 12
Pages: R1438-47
Publication
First Author: Rau AR
Year: 2020
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Disruption of GABA or glutamate release from POMC neurons in the adult mouse does not affect metabolic end points.
Volume: 319
Issue: 5
Pages: R592-R601
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: hypothalamus
Notes: FACs sorted Pomc reporter neurons from arcuate nuclei
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: hypothalamus
Notes: FACs sorted Pomc reporter neurons from arcuate nuclei
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: hypothalamus
Notes: FACs sorted Pomc reporter neurons from arcuate nuclei
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 15.5
Stage: 23
Structure . Name: hypothalamus
Notes: FACs sorted Pomc reporter neurons from arcuate nuclei
Curation Status: Curated
Publication  
First Author: Tse EK
Year: 2018
Journal: Mol Cell Endocrinol
Title: Palmitate induces neuroinflammation, ER stress, and Pomc mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate.
Volume: 472
Pages: 40-49
Publication
First Author: Zhou Y
Year: 2001
Journal: J Neuroendocrinol
Title: Ablation of pituitary pro-opiomelanocortin (POMC) cells produces alterations in hypothalamic POMC mRNA levels and midbrain mu opioid receptor binding in a conditional transgenic mouse model.
Volume: 13
Issue: 9
Pages: 808-17
Publication
First Author: Tang Q
Year: 2021
Journal: FASEB J
Title: Sirtuin 6 supra-physiological overexpression in hypothalamic pro-opiomelanocortin neurons promotes obesity via the hypothalamus-adipose axis.
Volume: 35
Issue: 3
Pages: e21408
Publication
First Author: Shi H
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis.
Volume: 294
Issue: 3
Pages: E630-9
Publication  
First Author: Dragano NRV
Year: 2024
Journal: Mol Metab
Title: Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.
Volume: 79
Pages: 101840
Publication  
First Author: Leyrer-Jackson JM
Year: 2022
Journal: Brain Res
Title: Sex differences and the lack of effects of chemogenetic manipulation of pro-opiomelanocortin (POMC) neurons on alcohol consumption in male and female mice.
Volume: 1786
Pages: 147901
Publication
First Author: Long L
Year: 2014
Journal: J Clin Invest
Title: PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding.
Volume: 124
Issue: 9
Pages: 4017-27
Publication
First Author: Kievit P
Year: 2006
Journal: Cell Metab
Title: Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.
Volume: 4
Issue: 2
Pages: 123-32
Publication
First Author: Xu Y
Year: 2008
Journal: Neuron
Title: 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis.
Volume: 60
Issue: 4
Pages: 582-9
Publication
First Author: Li H
Year: 2023
Journal: Nat Commun
Title: The melanocortin action is biased toward protection from weight loss in mice.
Volume: 14
Issue: 1
Pages: 2200
Publication
First Author: Xu Y
Year: 2010
Journal: Nat Neurosci
Title: 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver.
Volume: 13
Issue: 12
Pages: 1457-9
Publication
First Author: Xiao Y
Year: 2017
Journal: Diabetes
Title: ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.
Volume: 66
Issue: 5
Pages: 1146-1158
Publication
First Author: Janoschek R
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.
Volume: 103
Issue: 28
Pages: 10707-12
Publication
First Author: Mori H
Year: 2009
Journal: Cell Metab
Title: Critical role for hypothalamic mTOR activity in energy balance.
Volume: 9
Issue: 4
Pages: 362-74
Publication
First Author: Könner AC
Year: 2007
Journal: Cell Metab
Title: Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
Volume: 5
Issue: 6
Pages: 438-49
Publication
First Author: Wang X
Year: 2014
Journal: Diabetologia
Title: Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons.
Volume: 57
Issue: 1
Pages: 236-45
Publication
First Author: Shin AC
Year: 2017
Journal: Diabetes
Title: Insulin Receptor Signaling in POMC, but Not AgRP, Neurons Controls Adipose Tissue Insulin Action.
Volume: 66
Issue: 6
Pages: 1560-1571
Publication
First Author: Quan W
Year: 2012
Journal: Endocrinology
Title: Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response.
Volume: 153
Issue: 4
Pages: 1817-26
Publication
First Author: Fricker LD
Year: 2021
Journal: Cell Chem Biol
Title: Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary.
Volume: 28
Issue: 1
Pages: 105-112.e4
Publication
First Author: Hill JW
Year: 2010
Journal: Cell Metab
Title: Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility.
Volume: 11
Issue: 4
Pages: 286-97
Publication
First Author: Hill JW
Year: 2009
Journal: Endocrinology
Title: Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.
Volume: 150
Issue: 11
Pages: 4874-82