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Search results 1101 to 1200 out of 1222 for Ptf1a

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Type Details Score
Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE146238 | Positive auto-feedback regulation of Ptf1a transcription generates the levels of PTF1A required to specify dorsal spinal cord inhibitory neurons
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Regulatory Region
MGI:7704144 | Rr499
Type: enhancer
Organism: mouse, laboratory
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HT Experiment
GSE112935 | RNA-seq analysis dataset: FACS-sorted Ptf1a-lineage cells from E14.5 hypothalamus of Ptf1a hetero and homozygous mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
23339455 | J:196509
First Author: Campos ML
Year: 2013
Journal: Biochem J
Title: ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.
Volume: 451
Issue: 3
Pages: 395-405
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Regulatory Region
MGI:7704145 | Rr500
Type: enhancer
Organism: mouse, laboratory
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Interaction Experiment
Miyatsuka T (2007)
Description: Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III.
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HT Experiment
GSE86568 | Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation and Homeostasis by PTF1A [E18.5 RNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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GXD Expression
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 3I
Note: Some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors).
Specimen Label: 3I
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7853889
Assay Type: RNA in situ
Annotation Date: 2025-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7852792
Age: embryonic day 14.5
Note: Exocrine cell marker. Expression overlaps completely with Ptf1a staining.
Specimen Label: 2B
Detected: true
Specimen Num: 1
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HT Experiment
E-GEOD-26816 | Comparative gene expression of mouse Pancreatic specific transcription factor 1a (Ptf1a/p48) in pancreatic progenitor cells
Series Id: GSE26816
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Ptf1a<em1(cre/ERT2)Smoc> | MGI:6758049
Name: pancreas specific transcription factor, 1a; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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DO Term
DOID:0060988 | pancreatic agenesis 2
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7580782
Age: embryonic day 12.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: S2B"
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: S2A"
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6194268
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194384
Age: embryonic day 12.5
Image: 3C
Note: Expression was detected in postmitotic GABAergic neurons. There was no overlap with Ptf1a expression.
Specimen Label: 3C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6194268
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194386
Age: embryonic day 12.5
Image: 3C
Note: Expression was detected in postmitotic GABAergic neurons. There was no overlap with Ptf1a expression.
Specimen Label: 3C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5A Pdx-1 (lower)
Note: Expression coincident with Ptf1a throughout ventral pancreatic epithelium, except for first wave endocrine cells.
Specimen Label: 5A Pdx-1 (lower)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5A Pdx-1 (upper)
Note: Expression coincident with Ptf1a throughout dorsal pancreatic epithelium, except for first wave endocrine cells.
Specimen Label: 5A Pdx-1 (upper)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6695727
Age: embryonic day 11.5
Note: Expression still coincides with that of Ptf1a in almost all pancreatic epithelial cells.
Specimen Label: E11.5 +/+ not shown
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7580782
Age: embryonic day 11.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: 2I"
Detected: true
Specimen Num: 8
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Allele
Atoh1<tm2(Ptf1a)Mhos> | MGI:5617550
Name: atonal bHLH transcription factor 1; targeted mutation 2, Mikio Hoshino
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Strain
MGI:6429438 | C57BL/6JSmoc-Ptf1a<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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MP Term
MP:0021099 | abnormal dorsal interneuron LA morphology
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HT Experiment
GSE55831 | Transcription Factor Network Specifying Inhibitory versus Excitatory Neurons in the Dorsal Spinal Cord [RNA-Seq]
Series Id: E-GEOD-55831
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7580782
Age: embryonic day 12.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2B'
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2A'
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7580782
Age: embryonic day 9.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2E
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2F
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6695727
Age: embryonic day 9.5
Image: S3A/D Pdx-1
Note: Expression coincide with that of Ptf1a in vast majority of pancreatic epithelial cells from E9.5 to E10.5.
Specimen Label: S3A/D Pdx-1
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7580782
Age: embryonic day 11.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2G
Detected: true
Specimen Num: 18
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Publication
19067490 | -
First Author: Jiang Z
Year: 2008
Journal: PLoS Biol
Title: Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish.
Volume: 6
Issue: 11
Pages: e293
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Allele
Tg(Rr499-lacZ)5enhMacd | MGI:7704146
Name: transgene insertion 5enh, Raymond J MacDonald
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr499-lacZ)5enh+promMacd | MGI:7704147
Name: transgene insertion 5enh+prom, Raymond J MacDonald
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr56358-lacZ)#Macd | MGI:7704148
Name: transgene insertion, Raymond J MacDonald
Allele Type: Transgenic
Attribute String: Reporter
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GXD Expression
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5B Pdx-1
Note: Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Ptf1a and Ngn3 in scattered cells throughout pancreatic epithelium.
Specimen Label: 5B Pdx-1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6695359
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695730
Age: embryonic day 10.5
Image: 5B Ngn3
Note: Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Ptf1a and Pdx1 in scattered cells throughout pancreatic epithelium.
Specimen Label: 5B Ngn3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7520313
Age: embryonic day 12.5
Image: 3B/C
Note: Expression was predominantly localized in the ventricular zone. Overlapping Ptf1a and Olig2 expression in GABAergic precursors was observed in the intermediary region of the ventricular zone.
Specimen Label: 3B/C
Detected: true
Specimen Num: 1
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Allele
Tg(Rr500-lacZ)#Macd | MGI:7704149
Name: transgene insertion, Raymond J MacDonald
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr499-EGFP)#Macd | MGI:7704150
Name: transgene insertion, Raymond J MacDonald
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr500-mCherry)#Jejo | MGI:7704165
Name: transgene insertion, Jane E Johnson
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Rr500<em3Jejo> | MGI:7705094
Name: regulatory region 500; endonuclease-mediated mutation 3, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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MP Term
MP:0021095 | abnormal dorsal interneuron 4 morphology
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GXD Expression
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 3A,G
Note: Triple labeling indicated that some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors) and other Olig2-positive cells express Lhx1 and Lhx5 (which mark postmitotic GABAergic neurons). The results indicate that Olig2 is expressed in both mitotic and postmitotic cells.
Specimen Label: 3A,G
Detected: true
Specimen Num: 2
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Allele
Ptf1a<tm2Macd> | MGI:3771319
 
Name: pancreas specific transcription factor, 1a; targeted mutation 2, Raymond MacDonald
Allele Type: Targeted
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Allele
Ptf1a<tm3.1(rtTA)Mgn> | MGI:5467924
Name: pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson
Allele Type: Targeted
Attribute String: RMCE-ready, Transactivator
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Allele
Ptf1a<tm3.1Mgn> | MGI:6470589
Name: pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson
Allele Type: Targeted
Attribute String: Epitope tag, Reporter
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Allele
Rr499<em4Jejo> | MGI:7705115
Name: regulatory region 499; endonuclease-mediated mutation 4, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr499<em5Jejo> | MGI:7705118
Name: regulatory region 499; endonuclease-mediated mutation 5, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr500<em2Jejo> | MGI:7705124
Name: regulatory region 500; endonuclease-mediated mutation 2, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr499<em3Jejo> | MGI:7705113
Name: regulatory region 499; endonuclease-mediated mutation 3, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Tg(Rr500-EGFP)#Jejo | MGI:7705078
Name: transgene insertion, Jane E Johnson
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Rr499<em1Jejo> | MGI:7705091
Name: regulatory region 499; endonuclease-mediated mutation 1, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr499<em2Jejo> | MGI:7705092
Name: regulatory region 499; endonuclease-mediated mutation 2, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr500<em1Jejo> | MGI:7705093
Name: regulatory region 500; endonuclease-mediated mutation 1, Jane E Johnson
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Publication
21844183 | -
First Author: Li Y
Year: 2011
Journal: Cancer Res
Title: Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.
Volume: 71
Issue: 19
Pages: 6106-15
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Publication
23091072 | -
First Author: Jayasena CS
Year: 2012
Journal: J Cell Biol
Title: Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling.
Volume: 199
Issue: 3
Pages: 453-66
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Protein Domain
IPR034406 | RBMS3_RRM2
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of RBMS3 (RNA-binding motif, single-stranded-interacting protein 3). RBMS3 contains two RNA binding motifs and is closely related to the structure of the c-myc gene single-strand binding proteins (MSSPs). RBMS3 has been shown to exhibit tumour suppressor function via regulation of c-Myc and to bind/stabilize RNA in vitro []. It may posttranscriptionally regulate the transforming growth factor beta receptor pathway []. RBMS3 regulates the expression of Ptf1a (pancreas transcription factor 1 alpha subunit) [].
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GXD Expression
GXD Expression
Probe: MGI:5560706
Assay Type: RNA in situ
Annotation Date: 2014-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5561118
Age: embryonic day 12.5
Image: 4B, A/B inlay, B/C inlay
Note: Expression was detected in ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen Label: 4B, A/B inlay, B/C inlay
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5560706
Assay Type: RNA in situ
Annotation Date: 2014-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5561118
Age: embryonic day 12.5
Image: 4B', A'/B' inlay, B'/C' inlay
Note: Expression was detected in the ventricular layer. The signal overlaps with the caudal two thirds of Ptf1a (A/B inlay) and Mash1 (Ascl1 - B/C inlay). There was a gap in the expression domain (bracket) that is positive for Ptf1a and Mash1 (Ascl1).
Specimen Label: 4B', A'/B' inlay, B'/C' inlay
Detected: true
Specimen Num: 4
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HT Experiment
GSE108803 | Genome-wide chromatin accessibility and transcriptome profiling shows that minimal epigenome changes lead to coordinated transcriptional dysregulation of hedgehog signaling in Danforth's short tail mice (RNA-seq)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:5312105 | B6.129S6(SJL)-Ptf1a<tm3.1(rtTA)Mgn>/Mmjax
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6474321 | B6;129S6-Ptfl1a<tm3.1Mgn>/Vu
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Ptf1a/Ptf1a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Allele
Cbll<Tg(Alb-KL)7-2Mhos> | MGI:3771564
Name: cerebelless; transgene insertion 7-2, Mikio Hoshino
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Null/knockout
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Allele
Ascl1<tm1(Neurog2)Fgu> | MGI:2388165
Name: achaete-scute family bHLH transcription factor 1; targeted mutation 1, Francois Guillemot
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Genotype
Genotype
Symbol: Ascl1/Ascl1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cbll/Cbll
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ptf1a/Ptf1a
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Allele
Tlx3<tm1Sjk> | MGI:2180105
Name: T cell leukemia, homeobox 3; targeted mutation 1, Stanley J Korsmeyer
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Lbx1<em1Mwil> | MGI:6864154
Name: ladybird homeobox 1; endonuclease-mediated mutation 1, Megan J Wilson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tlx1/Tlx1 Tlx3/Tlx3
Background: involves: 129S2/SvPas * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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