|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1101 to 1200 out of 3113 for Rac1

<< First    < Previous  |  Next >    Last >>
0.034s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_16
Specimen Label: euxassay_007357_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_17
Specimen Label: euxassay_007357_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_18
Specimen Label: euxassay_007357_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_19
Specimen Label: euxassay_007357_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_20
Specimen Label: euxassay_007357_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_21
Specimen Label: euxassay_007357_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_22
Specimen Label: euxassay_007357_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_23
Specimen Label: euxassay_007357_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7716666
Age: embryonic day 13.5
Image: S6cA
Specimen Label: S6cA
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7716666
Age: embryonic day 14.5
Image: S6cC
Specimen Label: S6cC
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7716666
Age: embryonic day 15.5
Image: S6cE
Specimen Label: S6cE
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7716666
Age: embryonic day 13.5
Image: S6cA
Specimen Label: S6cA
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7716666
Age: embryonic day 14.5
Image: S6cC
Specimen Label: S6cC
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7716661
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7716666
Age: embryonic day 15.5
Image: S6cE
Specimen Label: S6cE
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_07
Specimen Label: euxassay_007357_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_08
Specimen Label: euxassay_007357_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_09
Specimen Label: euxassay_007357_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_10
Specimen Label: euxassay_007357_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_11
Specimen Label: euxassay_007357_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_13
Specimen Label: euxassay_007357_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_14
Specimen Label: euxassay_007357_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_15
Specimen Label: euxassay_007357_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_16
Specimen Label: euxassay_007357_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1036388
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824746
Age: embryonic day 14.5
Image: euxassay_007357_17
Specimen Label: euxassay_007357_17
Detected: true
Specimen Num: 17
•
•
•
•
•
Publication
27849309 | J:257609
First Author: Ortega MC
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Activation of Rac1 and RhoA Preserve Corneal Endothelial Barrier Function.
Volume: 57
Issue: 14
Pages: 6210-6222
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0019839 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0021895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0021854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0021836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0021861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0021635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1923520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0022300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0021153 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0021601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0021725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0021707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0021797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0021730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0022322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0020895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0021205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0019844 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0020736 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
HT Experiment
GSE98715 | Protein kinase 7 regulating extracellular matrix assemblies and intracellular RAC1 and myosin II activities in the mesenchyme is important to Wolffian duct morphogenesis.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Interaction Experiment
Wu PR (2023)
Description: Wdr4 promotes cerebellar development and locomotion through Arhgap17-mediated Rac1 activation.
•
•
•
•
•
Publication
23071154 | J:193930
First Author: Wang S
Year: 2012
Journal: J Cell Biol
Title: Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
Volume: 199
Issue: 2
Pages: 331-45
•
•
•
•
•
Publication
21828072 | J:176680
First Author: Pesaresi MG
Year: 2011
Journal: Hum Mol Genet
Title: Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation.
Volume: 20
Issue: 21
Pages: 4196-208
•
•
•
•
•
Publication
20353788 | J:160757
First Author: Santibáñez JF
Year: 2010
Journal: FEBS Lett
Title: Rac1 modulates TGF-beta1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes.
Volume: 584
Issue: 11
Pages: 2305-10
•
•
•
•
•
Publication
26977077 | J:232405
First Author: Sabbir MG
Year: 2016
Journal: Biol Open
Title: Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation.
Volume: 5
Issue: 4
Pages: 452-60
•
•
•
•
•
Publication
31040292 | J:297739
First Author: Li SY
Year: 2019
Journal: Sci Rep
Title: FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy.
Volume: 9
Issue: 1
Pages: 6693
•
•
•
•
•
Publication
27904138 | J:241799
First Author: Yu J
Year: 2017
Journal: Leukemia
Title: Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib.
Volume: 31
Issue: 6
Pages: 1333-1339
•
•
•
•
•
Publication
33603169 | J:303966
First Author: Turgu B
Year: 2021
Journal: Oncogene
Title: HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
Volume: 40
Issue: 11
Pages: 1988-2001
•
•
•
•
•
Publication
29949770 | J:270808
First Author: Morikawa M
Year: 2018
Journal: Cell Rep
Title: The Molecular Motor KIF21B Mediates Synaptic Plasticity and Fear Extinction by Terminating Rac1 Activation.
Volume: 23
Issue: 13
Pages: 3864-3877
•
•
•
•
•
Publication
17440041 | J:248221
First Author: Tolias KF
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development.
Volume: 104
Issue: 17
Pages: 7265-70
•
•
•
•
•
Publication
17485492 | J:134723
First Author: Bass MD
Year: 2007
Journal: J Cell Biol
Title: Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix.
Volume: 177
Issue: 3
Pages: 527-38
•
•
•
•
•
Publication
20228810 | J:160637
First Author: Anitei M
Year: 2010
Journal: Nat Cell Biol
Title: Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.
Volume: 12
Issue: 4
Pages: 330-40
•
•
•
•
•
Publication
22117219 | J:180438
First Author: Oberoi TK
Year: 2012
Journal: EMBO J
Title: IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation.
Volume: 31
Issue: 1
Pages: 14-28
•
•
•
•
•
Publication
34557485 | J:311153
 
First Author: Gahankari A
Year: 2021
Journal: Front Cell Dev Biol
Title: Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development.
Volume: 9
Pages: 704769
•
•
•
•
•
Publication
17093062 | J:121008
First Author: Chang F
Year: 2007
Journal: Mol Biol Cell
Title: FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.
Volume: 18
Issue: 1
Pages: 253-64
•
•
•
•
•
Publication
20696765 | J:204642
First Author: Li X
Year: 2010
Journal: J Biol Chem
Title: Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase.
Volume: 285
Issue: 42
Pages: 32436-45
•
•
•
•
•
Publication
16772332 | J:110344
First Author: Wheeler AP
Year: 2006
Journal: J Cell Sci
Title: Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.
Volume: 119
Issue: Pt 13
Pages: 2749-57
•
•
•
•
•
Publication
28775002 | J:292987
First Author: Sun Y
Year: 2017
Journal: J Am Soc Nephrol
Title: Kindlin-2 Association with Rho GDP-Dissociation Inhibitor α Suppresses Rac1 Activation and Podocyte Injury.
Volume: 28
Issue: 12
Pages: 3545-3562
•
•
•
•
•
Publication
19738201 | J:206561
First Author: Humphries JD
Year: 2009
Journal: Sci Signal
Title: Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.
Volume: 2
Issue: 87
Pages: ra51
•
•
•
•
•
Publication
32203420 | J:289585
First Author: Müller PM
Year: 2020
Journal: Nat Cell Biol
Title: Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Volume: 22
Issue: 4
Pages: 498-511
•
•
•
•
•
Publication
15231571 | J:94078
First Author: Montaner S
Year: 2004
Journal: Blood
Title: The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia.
Volume: 104
Issue: 9
Pages: 2903-11
•
•
•
•
•
Publication
22345572 | J:187489
First Author: Ghosh MC
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2.
Volume: 302
Issue: 9
Pages: L846-56
•
•
•
•
•
Publication
24186093 | J:207695
First Author: Ram R
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Mena associates with Rac1 and modulates connexin 43 remodeling in cardiomyocytes.
Volume: 306
Issue: 1
Pages: H154-9
•
•
•
•
•
Publication
25377089 | J:223667
First Author: Li AQ
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Exendin-4 promotes endothelial barrier enhancement via PKA- and Epac1-dependent Rac1 activation.
Volume: 308
Issue: 2
Pages: C164-75
•
•
•
•
•
Publication
27656019 | J:235566
First Author: Chen HH
Year: 2016
Journal: J Neurosci
Title: DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation.
Volume: 36
Issue: 38
Pages: 9792-804
•
•
•
•
•
Publication
28376111 | J:247377
First Author: Kim SY
Year: 2017
Journal: PLoS One
Title: Coordinated balance of Rac1 and RhoA plays key roles in determining phagocytic appetite.
Volume: 12
Issue: 4
Pages: e0174603
•
•
•
•
•
Publication
30012833 | J:264672
 
First Author: Bai Y
Year: 2018
Journal: J Cell Sci
Title: Balanced Rac1 activity controls formation and maintenance of neuromuscular acetylcholine receptor clusters.
Volume: 131
Issue: 15
•
•
•
•
•
Allele
Cyrib<+> | MGI:3819388
 
Name: CYFIP related Rac1 interactor B; wild type
Allele Type: Not Specified
•
•
•
•
•
Allele
Cyria<+> | MGI:3819390
 
Name: CYFIP related Rac1 interactor A; wild type
Allele Type: Not Specified
•
•
•
•
•
Publication
22767509 | J:199684
First Author: Park AR
Year: 2012
Journal: J Cell Sci
Title: Regulation of dendritic arborization by BCR Rac1 GTPase-activating protein, a substrate of PTPRT.
Volume: 125
Issue: Pt 19
Pages: 4518-31
•
•
•
•
•
Publication
20211865 | J:176101
First Author: Reil JC
Year: 2010
Journal: Cardiovasc Res
Title: Cardiac Rac1 overexpression in mice creates a substrate for atrial arrhythmias characterized by structural remodelling.
Volume: 87
Issue: 3
Pages: 485-93
•
•
•
•
•
Publication
16801538 | J:180470
First Author: Miyamoto Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology.
Volume: 103
Issue: 27
Pages: 10444-9
•
•
•
•
•
Pathway
R-MMU-9013149 | RAC1 GTPase cycle
•
•
•
•
•
Pathway
R-MMU-9032759 | NTRK2 activates RAC1
•
•
•
•
•
Publication
25829446 | J:260282
First Author: Mense SM
Year: 2015
Journal: Sci Signal
Title: PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Volume: 8
Issue: 370
Pages: ra32
•
•
•
•
•
Publication
20962234 | J:165475
First Author: Oh D
Year: 2010
Journal: J Neurosci
Title: Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.
Volume: 30
Issue: 42
Pages: 14134-44
•
•
•
•
•
Publication
21706053 | J:196252
First Author: Li X
Year: 2012
Journal: Oncogene
Title: Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton.
Volume: 31
Issue: 5
Pages: 595-610
•
•
•
•
•
Publication
31388105 | J:316919
First Author: Guo D
Year: 2021
Journal: Mol Psychiatry
Title: Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function.
Volume: 26
Issue: 5
Pages: 1505-1519
•
•
•
•
•
Publication
21911940 | J:178221
First Author: Akilesh S
Year: 2011
Journal: J Clin Invest
Title: Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis.
Volume: 121
Issue: 10
Pages: 4127-37
•
•
•
•
•
Publication
15673667 | J:263380
First Author: Choi J
Year: 2005
Journal: J Neurosci
Title: Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases.
Volume: 25
Issue: 4
Pages: 869-79
•
•
•
•
•
Publication
9699725 | J:48947
First Author: Scott GA
Year: 1998
Journal: J Invest Dermatol
Title: Rac1 mediates dendrite formation in response to melanocyte stimulating hormone and ultraviolet light in a murine melanoma model.
Volume: 111
Issue: 2
Pages: 243-50
•
•
•
•
•
Publication
20368346 | J:160182
First Author: Shen Y
Year: 2010
Journal: Infect Immun
Title: Toll-like receptor 2- and MyD88-dependent phosphatidylinositol 3-kinase and Rac1 activation facilitates the phagocytosis of Listeria monocytogenes by murine macrophages.
Volume: 78
Issue: 6
Pages: 2857-67
•
•
•
•
•
Publication
11084340 | -
First Author: Malecz N
Year: 2000
Journal: Curr Biol
Title: Synaptojanin 2, a novel Rac1 effector that regulates clathrin-mediated endocytosis.
Volume: 10
Issue: 21
Pages: 1383-6
•
•
•
•
•
Interaction Experiment
Courilleau D (2000)
Description: B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts.
•
•
•
•
•
Interaction Experiment
Williamson RC (2014)
Description: Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.
•
•
•
•
•
Interaction Experiment
Mueller PM (2020)
Description: Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
•
•
•
•
•
Publication
25063526 | J:218482
First Author: Lee J
Year: 2014
Journal: Biochim Biophys Acta
Title: Arhgef16, a novel Elmo1 binding partner, promotes clearance of apoptotic cells via RhoG-dependent Rac1 activation.
Volume: 1843
Issue: 11
Pages: 2438-47
•
•
•
•
•
Publication
29985482 | J:267431
First Author: Kotelevets L
Year: 2018
Journal: Oncogene
Title: The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
Volume: 37
Issue: 46
Pages: 6054-6068
•
•
•
•
•
Publication
29136506 | J:248841
First Author: Robles-Valero J
Year: 2017
Journal: Cancer Cell
Title: A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia.
Volume: 32
Issue: 5
Pages: 608-623.e9
•
•
•
•
•
DO Term
DOID:0080235 | autosomal dominant intellectual developmental disorder 48
•
•
•
•
•
Publication
24925969 | J:227101
First Author: Kobayashi K
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Stromal cell-derived factor-1α/C-X-C chemokine receptor type 4 axis promotes endothelial cell barrier integrity via phosphoinositide 3-kinase and Rac1 activation.
Volume: 34
Issue: 8
Pages: 1716-22
•
•
•
•
•
Publication
30257103 | J:271757
First Author: Ashino T
Year: 2018
Journal: Am J Physiol Cell Physiol
Title: Copper transporter ATP7A interacts with IQGAP1, a Rac1 binding scaffolding protein: role in PDGF-induced VSMC migration and vascular remodeling.
Volume: 315
Issue: 6
Pages: C850-C862
•
•
•
•
•
Pathway
R-MMU-8875555 | MET activates RAP1 and RAC1
•
•
•
•
•
Allele
Cyrib<Gt(CSJ046)Byg> | MGI:3880941
 
Name: CYFIP related Rac1 interactor B; gene trap CSJ046, BayGenomics
Allele Type: Gene trapped
•
•
•
•
•
Allele
Cyria<Gt(OST66599)Lex> | MGI:4171324
 
Name: CYFIP related Rac1 interactor A; gene trap OST66599, Lexicon Genetics
Allele Type: Gene trapped
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom