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Search results 1101 to 1200 out of 1306 for Rad51

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Type Details Score
Publication
29281624 | -
First Author: Lafuente-Barquero J
Year: 2017
Journal: PLoS Genet
Title: The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage.
Volume: 13
Issue: 12
Pages: e1007136
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Publication
28673972 | -
First Author: Pan X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.
Volume: 114
Issue: 29
Pages: E5940-E5949
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Protein Domain
IPR004585 | DNA_recomb/repair_Rad52
Type: Family
Description: Rad52 was identified in Saccharomyces cerevisiae (Baker's yeast) as a component of the homologous recombination repair pathway and to play an important role in both meiotic and mitotic recombination. The human protein is highly homologous in both structure and function. In the presence of absence of DNA, Rad52 forms ring-shaped oligomers which bind both single and double stranded DNA, stimulating annealing of complimentary DNA strands and promoting ligation of both cohesive and blunt-end fragments. Rad52 may act as a recombination mediator, optimising catalysis of strand exchange by the Rad51 protein.A C-terminal self-association domain has been identified that mediates formation of higher order oligomers of Rad52 rings. Formation of these oligomers may be important for interaction with more than one DNA molecule [].
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Protein Domain
IPR042525 | Rad52_Rad59_Rad22_sf
Type: Homologous_superfamily
Description: The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This superfamily includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs [].Rad52 was identified in Saccharomyces cerevisiae (Baker's yeast) as a component of the homologous recombination repair pathway and to play an important role in both meiotic and mitotic recombination. The human protein is highly homologous in both structure and function. Inthe presence of absence of DNA, Rad52 forms ring-shaped oligomers which bind both single and double stranded DNA, stimulating annealing of complimentary DNA strands and promoting ligation of both cohesive and blunt-end fragments. Rad52 may act as a recombination mediator, optimising catalysis of strand exchange by the Rad51 protein.A C-terminal self-association domain has been identified that mediates formation of higher order oligomers of Rad52 rings. Formation of these oligomers may be important for interaction with more than one DNA molecule [].
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Protein Domain
IPR039686 | FANCM/Mph1-like
Type: Family
Description: This entry includes a group of evolutionarily conserved ATP-dependent DNA helicases/translocases including human FANCM (Fanconi anemia group M protein) and its homologues, such as Mph1 from S. cerevisiae and Fml1/2 from S. pombe. FANCM is part of the FA complex that repair the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination []. It also plays a critical role in the replication stress response []. Mph1 can unwind Rad51 D-loops and extended D-loops []. It has been shown to be regulated by the Smc5/6 complex [, ]. Fml1 promotes Rad51-dependent gene conversion at stalled/blocked replication forks and limits crossing over during mitotic double-strand break repair [, ].
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Publication
12226092 | -
First Author: Lloyd JA
Year: 2002
Journal: J Biol Chem
Title: Correlation of biochemical properties with the oligomeric state of human rad52 protein.
Volume: 277
Issue: 48
Pages: 46172-8
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Publication
26920759 | -
First Author: Yimit A
Year: 2016
Journal: Genetics
Title: MTE1 Functions with MPH1 in Double-Strand Break Repair.
Volume: 203
Issue: 1
Pages: 147-57
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Publication
8581742 | J:32671
First Author: Sato S
Year: 1995
Journal: DNA Res
Title: Characterization of a mouse recA-like gene specifically expressed in testis.
Volume: 2
Issue: 3
Pages: 147-50
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Publication
22771120 | J:187623
First Author: Lutzmann M
Year: 2012
Journal: Mol Cell
Title: MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.
Volume: 47
Issue: 4
Pages: 523-34
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Publication
23333306 | J:197099
First Author: Escribano-Díaz C
Year: 2013
Journal: Mol Cell
Title: A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Volume: 49
Issue: 5
Pages: 872-83
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Publication
26833090 | J:233035
First Author: Trego KS
Year: 2016
Journal: Mol Cell
Title: Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability.
Volume: 61
Issue: 4
Pages: 535-546
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Publication
29976923 | J:266323
First Author: Widger A
Year: 2018
Journal: Nat Commun
Title: ATR is a multifunctional regulator of male mouse meiosis.
Volume: 9
Issue: 1
Pages: 2621
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Publication
30704900 | J:274082
First Author: Zong D
Year: 2019
Journal: Mol Cell
Title: BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Volume: 73
Issue: 6
Pages: 1267-1281.e7
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Publication
31653568 | J:286257
First Author: Callen E
Year: 2020
Journal: Mol Cell
Title: 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Volume: 77
Issue: 1
Pages: 26-38.e7
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Publication
25218637 | J:217712
First Author: Pefani DE
Year: 2014
Journal: Nat Cell Biol
Title: RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.
Volume: 16
Issue: 10
Pages: 962-71, 1-8
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Publication
22789542 | J:191013
First Author: Schlacher K
Year: 2012
Journal: Cancer Cell
Title: A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
Volume: 22
Issue: 1
Pages: 106-16
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Publication
30827889 | J:277880
First Author: Ma J
Year: 2019
Journal: Cancer Cell
Title: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.
Volume: 35
Issue: 3
Pages: 504-518.e7
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Publication
17425408 | J:122037
First Author: Bannister LA
Year: 2007
Journal: PLoS Biol
Title: A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.
Volume: 5
Issue: 5
Pages: e105
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Publication
17115026 | J:140233
First Author: De La Fuente R
Year: 2006
Journal: Nat Cell Biol
Title: Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells.
Volume: 8
Issue: 12
Pages: 1448-54
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Publication
29977027 | J:267878
First Author: Pacheco S
Year: 2018
Journal: Nat Commun
Title: ATR is required to complete meiotic recombination in mice.
Volume: 9
Issue: 1
Pages: 2622
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Publication
30257212 | J:271205
First Author: Nacson J
Year: 2018
Journal: Cell Rep
Title: BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Volume: 24
Issue: 13
Pages: 3513-3527.e7
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Publication
30305635 | J:268570
First Author: Abreu CM
Year: 2018
Journal: Nat Commun
Title: Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination.
Volume: 9
Issue: 1
Pages: 3961
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Publication
31291576 | J:288366
First Author: Gross KM
Year: 2019
Journal: Cell Rep
Title: Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium.
Volume: 28
Issue: 2
Pages: 394-407.e6
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Publication
27037238 | J:232116
First Author: Michl J
Year: 2016
Journal: EMBO J
Title: Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.
Volume: 35
Issue: 9
Pages: 909-23
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Publication
11861370 | J:75026
First Author: McAllister KA
Year: 2002
Journal: Cancer Res
Title: Cancer susceptibility of mice with a homozygous deletion in the COOH-terminal domain of the Brca2 gene.
Volume: 62
Issue: 4
Pages: 990-4
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Publication
32989256 | J:299665
First Author: Xu Z
Year: 2020
Journal: Oncogene
Title: Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.
Volume: 39
Issue: 47
Pages: 7051-7062
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Publication
30528234 | J:291226
First Author: Jeon Y
Year: 2019
Journal: Biochem Biophys Res Commun
Title: TopBP1 deficiency impairs the localization of proteins involved in early recombination and results in meiotic chromosome defects during spermatogenesis.
Volume: 508
Issue: 3
Pages: 722-728
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Publication
18562292 | J:137202
First Author: Fouladkou F
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization.
Volume: 105
Issue: 25
Pages: 8585-90
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Publication
37378420 | J:355465
First Author: Liu C
Year: 2023
Journal: Nucleic Acids Res
Title: RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis.
Volume: 51
Issue: 14
Pages: 7357-7375
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Publication
32726637 | J:304325
First Author: Zhang F
Year: 2020
Journal: Cell Rep
Title: L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis.
Volume: 32
Issue: 4
Pages: 107974
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Publication
34326328 | J:322962
First Author: Ghouil R
Year: 2021
Journal: Nat Commun
Title: BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Volume: 12
Issue: 1
Pages: 4605
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Publication
8812453 | J:46976
First Author: Shen Z
Year: 1996
Journal: Genomics
Title: UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins.
Volume: 36
Issue: 2
Pages: 271-9
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Publication
9523196 | J:46082
First Author: Katagiri T
Year: 1998
Journal: Genes Chromosomes Cancer
Title: Multiple possible sites of BRCA2 interacting with DNA repair protein RAD51.
Volume: 21
Issue: 3
Pages: 217-22
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Publication
21357745 | J:170686
First Author: Agarwal S
Year: 2011
Journal: J Cell Biol
Title: ATP-dependent and independent functions of Rad54 in genome maintenance.
Volume: 192
Issue: 5
Pages: 735-50
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Publication
21947284 | J:178877
First Author: Gospodinov A
Year: 2011
Journal: Mol Cell Biol
Title: Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection.
Volume: 31
Issue: 23
Pages: 4735-45
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Publication
22344029 | J:185069
First Author: Adamson B
Year: 2012
Journal: Nat Cell Biol
Title: A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.
Volume: 14
Issue: 3
Pages: 318-28
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Publication
23754376 | J:197379
First Author: Yuan J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: FIGNL1-containing protein complex is required for efficient homologous recombination repair.
Volume: 110
Issue: 26
Pages: 10640-5
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Publication
22635276 | J:216791
First Author: Luo K
Year: 2012
Journal: EMBO J
Title: Sumoylation of MDC1 is important for proper DNA damage response.
Volume: 31
Issue: 13
Pages: 3008-19
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Publication
26158445 | J:224365
 
First Author: He J
Year: 2015
Journal: Nat Commun
Title: PTEN regulates DNA replication progression and stalled fork recovery.
Volume: 6
Pages: 7620
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Publication
28698370 | J:243996
First Author: Yang Q
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: G9a coordinates with the RPA complex to promote DNA damage repair and cell survival.
Volume: 114
Issue: 30
Pages: E6054-E6063
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Publication
28860160 | J:245949
First Author: Xu S
Year: 2017
Journal: Genes Dev
Title: Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.
Volume: 31
Issue: 14
Pages: 1469-1482
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Publication
27345151 | J:253013
First Author: Wang Y
Year: 2016
Journal: Mol Cell
Title: Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62.
Volume: 63
Issue: 1
Pages: 34-48
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Publication
32644042 | J:293911
   
First Author: Zhang W
Year: 2020
Journal: Elife
Title: A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing.
Volume: 9
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Publication
32359443 | J:295420
First Author: Nacson J
Year: 2020
Journal: Mol Cell
Title: BRCA1 Mutational Complementation Induces Synthetic Viability.
Volume: 78
Issue: 5
Pages: 951-959.e6
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Publication
33020270 | J:302811
First Author: Wang C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors.
Volume: 117
Issue: 42
Pages: 26356-26365
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Publication
34179826 | J:307136
First Author: Zhou J
Year: 2021
Journal: Nat Cancer
Title: A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.
Volume: 2
Issue: 6
Pages: 598-610
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Publication
34253720 | J:308439
First Author: Prakash R
Year: 2021
Journal: Nat Commun
Title: Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex.
Volume: 12
Issue: 1
Pages: 4255
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Publication
28976962 | J:336816
First Author: Zhao W
Year: 2017
Journal: Nature
Title: BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
Volume: 550
Issue: 7676
Pages: 360-365
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Protein
Q8C610
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Publication
17397913 | J:211548
First Author: Zhao Y
Year: 2007
Journal: Cell
Title: Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.
Volume: 129
Issue: 2
Pages: 303-17
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Publication
21690297 | J:175085
First Author: Le Masson F
Year: 2011
Journal: Mol Cell Biol
Title: Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis.
Volume: 31
Issue: 16
Pages: 3410-23
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Protein
Q3TN53
Organism: Mus musculus/domesticus
Length: 747  
Fragment?: true
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Publication
38554279 | J:348335
First Author: Georgieva D
Year: 2024
Journal: Cell Rep
Title: BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks.
Volume: 43
Issue: 4
Pages: 114006
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Protein
Q9CXE6
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
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Protein
Q9EP87
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: false
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Protein
Q3UGT8
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
B5LBC4
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
Q9EQS6
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q9EQL4
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
P43352
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
G5E879
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
Q8VEE2
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: false
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Protein
Q8C779
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: false
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Protein
Q9CX47
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
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Protein
A0A0G2JGJ2
Organism: Mus musculus/domesticus
Length: 785  
Fragment?: false
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Protein
D3YVU6
Organism: Mus musculus/domesticus
Length: 1030  
Fragment?: false
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Protein
E0CZA6
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
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Publication
15161972 | -
First Author: Askree SH
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length.
Volume: 101
Issue: 23
Pages: 8658-63
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Publication
32640219 | -
First Author: Brannvoll A
Year: 2020
Journal: Cell Rep
Title: The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells.
Volume: 32
Issue: 1
Pages: 107849
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Publication
26966246 | -
First Author: Xue X
Year: 2016
Journal: Genes Dev
Title: Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1.
Volume: 30
Issue: 6
Pages: 687-99
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Publication
26966248 | -
First Author: Silva S
Year: 2016
Journal: Genes Dev
Title: Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.
Volume: 30
Issue: 6
Pages: 700-17
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Publication
18669648 | -
First Author: Dephoure N
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A quantitative atlas of mitotic phosphorylation.
Volume: 105
Issue: 31
Pages: 10762-7
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Protein Domain
IPR018838 | DUF2439
Type: Domain
Description: This domain can be found in proteins that have been implicated in telomere maintenance in Saccharomyces cerevisiae []and in meiotic chromosome segregation in Schizosaccharomyces pombe []. It can also be found in Mte1 (Mph1-associated telomere maintenance protein 1), human zinc finger protein ZGRF1 (C4ORF21) and fission yeast Dbl2 []. Mte1 is a D-loop-binding protein that interacts and stimulates the helicase and fork regression activities of Mph1 while inhibiting the ability of Mph1 to dissociate recombination intermediates. Mph1 and Mte1 interdependently colocalise at DNA damage-induced foci and dysfunctional telomeres. Mte1 is indicated to play a role in regulation of crossover recombination, response to replication stress, and telomere maintenance []. The fission yeast, Dbl2 is needed for cellular resistance to the topoisomerase I poison camptothecin, forms DNA damage-induced foci, and is needed for the optimal recruitment of Fml1 to DNA damage, while the human ZGRF1 protein has been linked to DNA cross-link repair and mutations of it have been found in a variety of human tumors []. ZGRF1 is a 5'-to-3'helicase that interacts with RAD51 and stimulates homologous recombination and, thus, promotes the repair of replication-blocking DNA lesions []. Having said that, there is no evidence to suggest that this domain is implicated in DNA damage resistance or for nuclear focus formation [].
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Protein
Q61880
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
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Protein
Q14AN8
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
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Protein
Q6PB43
Organism: Mus musculus/domesticus
Length: 1180  
Fragment?: false
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Publication
9716408 | J:49553
First Author: Freire R
Year: 1998
Journal: Genes Dev
Title: Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.
Volume: 12
Issue: 16
Pages: 2560-73
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Publication
11820814 | J:74632
First Author: Libby BJ
Year: 2002
Journal: Dev Biol
Title: The mouse meiotic mutation mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression.
Volume: 242
Issue: 2
Pages: 174-87
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Publication
15928951 | J:103876
First Author: Reinholdt LG
Year: 2005
Journal: Chromosoma
Title: Mei1 is epistatic to Dmc1 during mouse meiosis.
Volume: 114
Issue: 2
Pages: 127-34
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Publication
16675459 | J:114577
First Author: Pezza RJ
Year: 2006
Journal: J Biol Chem
Title: Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex.
Volume: 281
Issue: 27
Pages: 18426-34
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Publication
15096601 | J:89546
First Author: Tsai-Morris CH
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis.
Volume: 101
Issue: 17
Pages: 6373-8
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Publication
25642963 | J:219787
First Author: Ceccaldi R
Year: 2015
Journal: Nature
Title: Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Volume: 518
Issue: 7538
Pages: 258-62
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Publication
25642960 | J:219558
First Author: Mateos-Gomez PA
Year: 2015
Journal: Nature
Title: Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Volume: 518
Issue: 7538
Pages: 254-7
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Publication
25894966 | J:250814
First Author: Sun F
Year: 2015
Journal: Chromosoma
Title: Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis.
Volume: 124
Issue: 3
Pages: 397-415
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Publication
23593030 | J:223053
First Author: Becherel OJ
Year: 2013
Journal: PLoS Genet
Title: Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.
Volume: 9
Issue: 4
Pages: e1003435
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Publication
30042186 | J:280228
First Author: Yang Y
Year: 2018
Journal: J Med Genet
Title: XRCC2 mutation causes meiotic arrest, azoospermia and infertility.
Volume: 55
Issue: 9
Pages: 628-636
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Publication
27492080 | J:237046
First Author: Yan Z
Year: 2016
Journal: Reproduction
Title: Transcription factor ZFP38 is essential for meiosis prophase I in male mice.
Volume: 152
Issue: 5
Pages: 431-7
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Publication
16107704 | J:100407
First Author: Dendouga N
Year: 2005
Journal: Mol Cell Biol
Title: Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.
Volume: 25
Issue: 17
Pages: 7569-79
•
•
•
•
•
Publication
28894029 | J:248791
 
First Author: Mochizuki AL
Year: 2017
Journal: Mol Cell Biol
Title: PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.
Volume: 37
Issue: 23
•
•
•
•
•
Publication
26839262 | J:235544
First Author: Ghaleb AM
Year: 2016
Journal: Mol Cancer Res
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Volume: 14
Issue: 4
Pages: 385-96
•
•
•
•
•
Publication
25448685 | J:217529
First Author: Ganesan S
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage.
Volume: 281
Issue: 2
Pages: 203-10
•
•
•
•
•
Publication
26596988 | J:260045
First Author: Decarpentrie F
Year: 2016
Journal: Chromosoma
Title: Recombination between the mouse Y chromosome short arm and an additional Y short arm-derived chromosomal segment attached distal to the X chromosome PAR.
Volume: 125
Issue: 2
Pages: 177-88
•
•
•
•
•
Publication
16982732 | J:112932
First Author: Xing D
Year: 2006
Journal: Cancer Res
Title: A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.
Volume: 66
Issue: 18
Pages: 8949-53
•
•
•
•
•
Publication
23798389 | J:198698
First Author: Meng L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells.
Volume: 110
Issue: 28
Pages: 11415-20
•
•
•
•
•
Publication
9398851 | J:44388
First Author: Barlow C
Year: 1997
Journal: Nat Genet
Title: Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles.
Volume: 17
Issue: 4
Pages: 462-6
•
•
•
•
•
Publication
34601382 | J:320381
 
First Author: Prakash R
Year: 2021
Journal: DNA Repair (Amst)
Title: XRCC3 loss leads to midgestational embryonic lethality in mice.
Volume: 108
Pages: 103227
•
•
•
•
•
Publication
9735362 | J:51058
First Author: Barlow C
Year: 1998
Journal: Development
Title: Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I.
Volume: 125
Issue: 20
Pages: 4007-17
•
•
•
•
•
Publication
23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
•
•
•
•
•
Publication
12642502 | J:82308
First Author: Xu X
Year: 2003
Journal: Development
Title: Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice.
Volume: 130
Issue: 9
Pages: 2001-12
•
•
•
•
•
Publication
22915751 | J:193222
First Author: Juvekar A
Year: 2012
Journal: Cancer Discov
Title: Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.
Volume: 2
Issue: 11
Pages: 1048-63
•
•
•
•
•




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