| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
741
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
721
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5289684 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3573928 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7482274 |
| Age: |
postnatal day 7 |
| Image: |
S2H |
| Note: |
Expression in cells co-labeled for Tbx3 reporter. |
| Specimen Label: |
S2H |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rowley M |
| Year: |
2004 |
| Journal: |
J Mammary Gland Biol Neoplasia |
| Title: |
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
109-18 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
enhancer |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Renard CA |
| Year: |
2007 |
| Journal: |
Cancer Res |
| Title: |
Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. |
| Volume: |
67 |
| Issue: |
3 |
| Pages: |
901-10 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Female |
| Age: |
embryonic day 18.5 |
| Stage: |
26 |
| Structure . Name: |
ureter |
| Notes: |
control animals were Cre negative Tbx2 fl/?; Tbx3 fl/? |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Male |
| Age: |
embryonic day 14.5 |
| Stage: |
22 |
| Structure . Name: |
ureter |
| Notes: |
control animals were Cre negative Tbx2 fl/?; Tbx3 fl/? |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Allele |
| Name: |
T-box 3; endonuclease-mediated mutation 1, Fumiko Toyoshima |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Vincent M Christoffels |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
T-box 3; targeted mutation 1, Virginia Papaioannou |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tbx3/Tbx3 |
| Background: |
either: (involves: 129 * 129S1/Sv * 129X1/SvJ) or (involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6NTac) |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
T-box 3; endonuclease-mediated mutation 1, Matthias H Tschop |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Vincent M Christoffels |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
T-box 3; targeted mutation 4, Anne M Moon |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
regulatory region 55; endonuclease-mediated mutation 1, Axel Visel |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tbx3/Tbx3<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Vincent M Christoffels |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Rr55/Rr55 |
| Background: |
FVB-Rr55 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tbx3/Tbx3<+> |
| Background: |
involves: C57BL/6 * CBA/JNCrlj * ICR |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-cat,-TBX3)1Vmc/? Tg(Myh6-cre)2182Mds/? |
| Background: |
involves: FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-cat,-TBX3)1Vmc/? Tg(Nppa-cre)m-3+4Vmc/? |
| Background: |
Not Specified |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tbx3/Tbx3<+> |
| Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl * ICR |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tbx3/Tbx3<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
| Background: |
involves: 129S4/SvJaeSor |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seehawer M |
| Year: |
2018 |
| Journal: |
Nature |
| Title: |
Necroptosis microenvironment directs lineage commitment in liver cancer. |
| Volume: |
562 |
| Issue: |
7725 |
| Pages: |
69-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Galan-Caridad JM |
| Year: |
2007 |
| Journal: |
Cell |
| Title: |
Zfx controls the self-renewal of embryonic and hematopoietic stem cells. |
| Volume: |
129 |
| Issue: |
2 |
| Pages: |
345-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oh Y |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Transcriptional regulation of the postnatal cardiac conduction system heterogeneity. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
6550 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prince S |
| Year: |
2004 |
| Journal: |
Cancer Res |
| Title: |
Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. |
| Volume: |
64 |
| Issue: |
5 |
| Pages: |
1669-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang P |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
1588 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-cat,-TBX3)1Vmc/? Tg(Nppa-cre)3Vmc/? |
| Background: |
Not Specified |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(CAG-cat,-TBX3)1Vmc/? Tg(Nppa-cre)4Vmc/? |
| Background: |
Not Specified |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paxton C |
| Year: |
2002 |
| Journal: |
Gene |
| Title: |
Murine Tbx2 contains domains that activate and repress gene transcription. |
| Volume: |
283 |
| Issue: |
1-2 |
| Pages: |
117-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abrahams A |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
UV-mediated regulation of the anti-senescence factor Tbx2. |
| Volume: |
283 |
| Issue: |
4 |
| Pages: |
2223-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iha M |
| Year: |
2012 |
| Journal: |
Reproduction |
| Title: |
Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells. |
| Volume: |
143 |
| Issue: |
4 |
| Pages: |
477-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moreno-MarÃn N |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
10420 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Andreani C |
| Year: |
2023 |
| Journal: |
Sci Rep |
| Title: |
SIRT6 promotes metastasis and relapse in HER2-positive breast cancer. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
22000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato S |
| Year: |
2015 |
| Journal: |
J Biosci Bioeng |
| Title: |
Partial inhibition of differentiation associated with elevated protein levels of pluripotency factors in mouse embryonic stem cells expressing exogenous EGAM1N homeoprotein. |
| Volume: |
120 |
| Issue: |
5 |
| Pages: |
562-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee MJ |
| Year: |
2013 |
| Journal: |
Cell Tissue Res |
| Title: |
Expression of miR-206 during the initiation of mammary gland development. |
| Volume: |
353 |
| Issue: |
3 |
| Pages: |
425-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Galang G |
| Year: |
2020 |
| Journal: |
Circ Res |
| Title: |
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function. |
| Volume: |
127 |
| Issue: |
12 |
| Pages: |
1502-1518 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cho KW |
| Year: |
2012 |
| Journal: |
Dev Biol |
| Title: |
Retinoic acid signaling and the initiation of mammary gland development. |
| Volume: |
365 |
| Issue: |
1 |
| Pages: |
259-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh S |
| Year: |
2024 |
| Journal: |
Hepatol Commun |
| Title: |
Modulation of canonical Wnt signaling regulates peribiliary mesenchymal identity during homeostasis and injury. |
| Volume: |
8 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Villén J |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Large-scale phosphorylation analysis of mouse liver. |
| Volume: |
104 |
| Issue: |
5 |
| Pages: |
1488-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huttlin EL |
| Year: |
2010 |
| Journal: |
Cell |
| Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
| Volume: |
143 |
| Issue: |
7 |
| Pages: |
1174-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Church DM |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e1000112 |
|
•
•
•
•
•
|