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Search results 1101 to 1200 out of 1238 for Tbx5

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Type Details Score
Publication
19906857 | J:154982
First Author: Yun S
Year: 2009
Journal: Development
Title: Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.
Volume: 136
Issue: 23
Pages: 3895-906
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Publication
30347193 | J:270088
 
First Author: Wang Y
Year: 2018
Journal: J Mol Cell Cardiol
Title: NOTCH maintains developmental cardiac gene network through WNT5A.
Volume: 125
Pages: 98-105
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Publication
25670795 | J:238888
First Author: Luo W
Year: 2015
Journal: Development
Title: Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development.
Volume: 142
Issue: 4
Pages: 732-42
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Publication
15843414 | J:98489
First Author: Stennard FA
Year: 2005
Journal: Development
Title: Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation.
Volume: 132
Issue: 10
Pages: 2451-62
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Publication
32597756 | J:294824
   
First Author: Dias A
Year: 2020
Journal: Elife
Title: A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.
Volume: 9
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Publication
24705356 | J:213620
First Author: Kong P
Year: 2014
Journal: Hum Mol Genet
Title: Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Volume: 23
Issue: 16
Pages: 4215-31
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Publication
23342106 | J:195854
First Author: Zhu Y
Year: 2013
Journal: PLoS One
Title: Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
Volume: 8
Issue: 1
Pages: e54221
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Publication
31024170 | J:331853
First Author: Gao R
Year: 2019
Journal: Cell Res
Title: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.
Volume: 29
Issue: 6
Pages: 486-501
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Publication
23720040 | J:198655
First Author: Cai Z
Year: 2013
Journal: Development
Title: Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma.
Volume: 140
Issue: 13
Pages: 2711-23
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Publication
21983003 | J:178530
First Author: Cai X
Year: 2011
Journal: Dev Biol
Title: Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2.
Volume: 360
Issue: 2
Pages: 381-90
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Publication
26173459 | J:226104
First Author: Wang F
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development.
Volume: 309
Issue: 5
Pages: E487-99
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Publication
18356246 | J:134487
First Author: Suzuki A
Year: 2008
Journal: Development
Title: Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.
Volume: 135
Issue: 9
Pages: 1589-95
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Publication
23426374 | J:197830
First Author: Zhang R
Year: 2013
Journal: J Biol Chem
Title: Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.
Volume: 288
Issue: 15
Pages: 10275-85
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Publication
18462699 | J:155850
First Author: Lee D
Year: 2008
Journal: Cell Stem Cell
Title: ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Volume: 2
Issue: 5
Pages: 497-507
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Publication
29409032 | J:288982
First Author: Assenza MR
Year: 2018
Journal: Cardiovasc Res
Title: Critical role of phosphodiesterase 2A in mouse congenital heart defects.
Volume: 114
Issue: 6
Pages: 830-845
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Publication
38191655 | J:344186
First Author: Muñoz-Gallardo MDM
Year: 2024
Journal: Sci Rep
Title: miR-195b is required for proper cellular homeostasis in the elderly.
Volume: 14
Issue: 1
Pages: 810
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Publication
24335282 | J:212358
First Author: Singh AP
Year: 2014
Journal: Nucleic Acids Res
Title: Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.
Volume: 42
Issue: 5
Pages: 2958-75
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Publication
14614146 | J:86704
First Author: Maynard TM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A comprehensive analysis of 22q11 gene expression in the developing and adult brain.
Volume: 100
Issue: 24
Pages: 14433-8
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Publication
31434798 | J:309382
 
First Author: Sandireddy R
Year: 2019
Journal: JCI Insight
Title: Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.
Volume: 4
Issue: 16
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Publication
23341776 | J:195172
First Author: Lüdtke TH
Year: 2013
Journal: PLoS Genet
Title: Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b.
Volume: 9
Issue: 1
Pages: e1003189
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Publication
28827394 | J:245768
First Author: Landry-Truchon K
Year: 2017
Journal: Development
Title: HOXA5 plays tissue-specific roles in the developing respiratory system.
Volume: 144
Issue: 19
Pages: 3547-3561
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Publication
27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
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Publication
27026076 | J:236825
 
First Author: Langer D
Year: 2016
Journal: Nat Commun
Title: Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.
Volume: 7
Pages: 11063
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Publication
25336743 | J:222450
First Author: Uribe V
Year: 2014
Journal: Development
Title: Arid3b is essential for second heart field cell deployment and heart patterning.
Volume: 141
Issue: 21
Pages: 4168-81
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Publication
35512705 | J:325251
First Author: Chen A
Year: 2022
Journal: Cell
Title: Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays.
Volume: 185
Issue: 10
Pages: 1777-1792.e21
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Publication
32212902 | J:317550
First Author: Sakamoto T
Year: 2020
Journal: Circ Res
Title: A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.
Volume: 126
Issue: 12
Pages: 1685-1702
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Publication
34671097 | J:312414
First Author: Yogosawa S
Year: 2021
Journal: Commun Biol
Title: Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.
Volume: 4
Issue: 1
Pages: 1204
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Publication
16971476 | J:119560
First Author: Choi MY
Year: 2006
Journal: Development
Title: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
Volume: 133
Issue: 20
Pages: 4119-29
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE166970 | TBX5 G125R induces profound transcriptional deregulation and atrial dysfunction in vivo [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Sample
GSM1557542
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Tbx5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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HT Sample
GSM1557543
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Tbx5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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HT Sample
GSM1557544
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.0
Stage: 10
Structure . Name: embryo mesoderm
Notes: Tbx5 positive cell from an early allantoic bud stage embryo
Curation Status: Curated
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GXD Expression
GXD Expression
Probe: MGI:6116657
Assay Type: RNA in situ
Annotation Date: 2018-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6116672
Age: embryonic day 8.5
Image: 2E Tbx5-/-
Note: Authors report expression was roughly normal in Tbx5 null embryos.
Specimen Label: 2E Tbx5-/-
Detected: true
Specimen Num: 7
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Regulatory Region
MGI:7327296 | Rr208
Type: intronic_regulatory_region
Organism: mouse, laboratory
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HT Experiment
GSE167357 | TBX5 G125R induces profound transcriptional deregulation and atrial dysfunction in vivo [Tbx5_p.G125R]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Interaction Experiment
Koshiba-Takeuchi K (2006)
Description: Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.
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Interaction Experiment
Jeong HS (2015)
Description: Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development.
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HT Experiment
GSE139824 | Mouse_Tbx5_del_CreERT2_bulk_RNAseq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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GXD Expression
GXD Expression
Probe: MGI:1333200
Assay Type: RNA in situ
Annotation Date: 2009-06-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1678117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3846940
Age: embryonic day 10.5
Image: 1Q
Note: Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained.
Specimen Label: 1Q
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1335028
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7525264
Age: embryonic day 8.5-9.0
Image: 2K
Note: Expression was detected in a lateral region overlapping with the caudal-most domain of Tbx5 expression.
Specimen Label: 2K
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1333200
Assay Type: RNA in situ
Annotation Date: 2009-06-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3846940
Age: embryonic day 10.5
Image: 1Q
Note: Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained.
Specimen Label: 1Q
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1333200
Assay Type: RNA in situ
Annotation Date: 2009-06-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3846940
Age: embryonic day 11.5
Image: 1R
Note: Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained.
Specimen Label: 1R
Detected: true
Specimen Num: 3
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Transgene
MGI:7327319 | Tg(Rr208-lacZ)#Mlgn
Type: transgene
Organism: mouse, laboratory
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Publication
16880269 | -
First Author: Camarata T
Year: 2006
Journal: J Cell Biol
Title: LMP4 regulates Tbx5 protein subcellular localization and activity.
Volume: 174
Issue: 3
Pages: 339-48
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Interaction Experiment
Bruneau BG (2001)
Description: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
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Publication
28469241 | -
First Author: Khalil A
Year: 2017
Journal: Sci Rep
Title: A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases.
Volume: 7
Issue: 1
Pages: 1416
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Allele
Rr426<em1Axvi> | MGI:7489686
Name: regulatory region 426; endonuclease-mediated mutation 1, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Tg(Tbx5*-cre)1Mlgn | MGI:5818475
Name: transgene insertion 1, Malcolm P Logan
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Rr108735<em1Axvi> | MGI:7489687
Name: regulatory region 108735; endonuclease-mediated mutation 1, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Del(5Rr426-Rr108735)1Axvi | MGI:7489863
Name: deletion, Chr 5, Axel Visel 1
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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HT Experiment
GSE237090 | Bulk RNA seq of P0 aCMs and P28 aCMs
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
17196583 | J:119193
First Author: Wakahara T
Year: 2007
Journal: Dev Biol
Title: Fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish.
Volume: 303
Issue: 2
Pages: 527-35
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Strain
MGI:7489916 | FVB-Rr426<em1Axvi>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7489918 | FVB-Del(5Rr426-Rr108735)1Axvi
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Rr51<em1Axvi> | MGI:7489587
Name: regulatory region 51; endonuclease-mediated mutation 1, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr55<em1Axvi> | MGI:7489591
Name: regulatory region 55; endonuclease-mediated mutation 1, Axel Visel
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Del(5Rr426-Rr108735)1Axvi/Del(5Rr426-Rr108735)1Axvi
Background: FVB-Del(5Rr426-Rr108735)1Axvi
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr426/Rr426
Background: FVB-Rr426
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(CAG-cat,-Tbx5)1Nemr | MGI:4361178
Name: transgene insertion 1, Mona Nemer
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7489908 | FVB-Rr51<em1Axvi>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6348306 | FVB/NCrl-Rr51<em1Axvi>/Mmucd
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Strain
MGI:6348310 | FVB/NCrl-Rr55<em1Axvi>/Mmucd
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Strain
MGI:7489914 | FVB-Rr55<em1Axvi>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rr51/Rr51
Background: FVB-Rr51
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr55/Rr55
Background: FVB-Rr55
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9CQS3
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
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Publication
21615908 | J:174073
 
First Author: Lakner J
Year: 2011
Journal: BMC Biochem
Title: Characterization of the expression, promoter activity and molecular architecture of fibin.
Volume: 12
Pages: 26
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Protein Domain
IPR026772 | Fibin
Type: Family
Description: Fin bud initiation factor (Fibin) forms disulfide-linked homodimers. It seems to also exist as monomers []. It localises in endoplasmic reticulum and golgi apparatus [, ]. In zebrafish, Fibin is essential for the initiation of pectoral fin bud formation. It potentially acts downstream of retinoic acid and Wnt signaling and is required for tbx5 expression in the lateral plate mesoderm of presumptive pectoral fin bud regions []. In mammals is expressed in cerebellum, skeletal muscle and other embryonic and adult tissues, suggesting a relevant role during embryogenesis and adult life [].
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HT Experiment
E-GEOD-77576 | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Series Id: GSE77576
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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