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Search results 1101 to 1200 out of 5471 for Tyr

0.017s

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Type Details Score
Publication
First Author: McLoughlin DM
Year: 1996
Journal: FEBS Lett
Title: The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system.
Volume: 397
Issue: 2-3
Pages: 197-200
Strain
Attribute String: mutant strain
Allele  
Name: warfarin resistance
Allele Type: Chemically induced (other)
Genotype
Symbol: Tyr/Tyr
Background: involves: SELH/Bc
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: Not specified
Strain
Attribute String: Not specified
Strain
Attribute String: mutant stock, radiation induced mutation, spontaneous mutation
Publication  
First Author: Peters J
Year: 1982
Journal: Mouse News Lett
Title: Polycythaemia (Hbbc).
Volume: 67
Pages: 19
Allele  
Name: sterol O-acyltransferase 1; adrenocortical lipid depletion
Allele Type: Spontaneous
Strain
Attribute String: chemically induced mutation, congenic, mutant strain
Strain
Attribute String: mutant stock, transgenic, wild-type allele
Allele  
Name: immunoglobulin heavy chain complex; targeted mutation 6, University of Cologne
Allele Type: Targeted
Allele
Name: transgene insertion 6775, Lluis Montoliu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant stock, outbred stock, transgenic, congenic
Publication
First Author: Giménez E
Year: 2004
Journal: Pigment Cell Res
Title: A transgenic mouse model with inducible Tyrosinase gene expression using the tetracycline (Tet-on) system allows regulated rescue of abnormal chiasmatic projections found in albinism.
Volume: 17
Issue: 4
Pages: 363-70
Allele
Name: fukutin related protein; targeted mutation 1, S C Brown
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: targeted mutation, mutant stock
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 7.1, Masato Ohtsuka
Allele Type: Targeted
Attribute String: Conditional ready, Knockdown, Reporter, RMCE-ready
Allele  
Name: serine peptidase inhibitor, Kazal type 5; transposon insertion 1498, Paul A Overbeek
Allele Type: Transposon induced
Allele
Name: adaptor-related protein complex 2, beta 1 subunit; transgene insertion 427, Paul Overbeek
Allele Type: Transgenic
Attribute String: Null/knockout, Reporter
Strain
Attribute String: mutant strain, transgenic, coisogenic
Publication  
First Author: Mattiske D
Year: 2019
Journal: Differentiation
Title: A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice.
Volume: 112
Pages: 1-6
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Genotype
Symbol: Pax6<8Neu>/Pax6<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Pax6<8Neu>/Pax6<8Neu>
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: STOCK Tyr/Tyr
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Fkrp/Fkrp
Background: involves: C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hbb/Hbb
Background: involves: 101/H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hbb/Hbb<+>
Background: involves: 101/H
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: involves: C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tyr/Tyr
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Mitf/Mitf Tg(Tyr-Tfec)#Bhar/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Leat1/Leat1
Background: FVB/NJ-Leat1
Zygosity: hm
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ingley E
Year: 2008
Journal: Biochim Biophys Acta
Title: Src family kinases: regulation of their activities, levels and identification of new pathways.
Volume: 1784
Issue: 1
Pages: 56-65
Publication
First Author: Engen JR
Year: 2008
Journal: Cell Mol Life Sci
Title: Structure and dynamic regulation of Src-family kinases.
Volume: 65
Issue: 19
Pages: 3058-73
Publication
First Author: Ochi H
Year: 2000
Journal: Int Immunol
Title: Negative regulation of B cell receptor-mediated signaling in B-1 cells through CD5 and Ly49 co-receptors via Lyn kinase activity.
Volume: 12
Issue: 10
Pages: 1417-23
Publication
First Author: Xu Y
Year: 2005
Journal: Immunity
Title: Lyn tyrosine kinase: accentuating the positive and the negative.
Volume: 22
Issue: 1
Pages: 9-18
Publication  
First Author: Sampson M
Year: 2007
Journal: Front Biosci
Title: Src kinases in G-CSF receptor signaling.
Volume: 12
Pages: 1463-74
Protein Domain
Type: Domain
Description: Lyn is a member of the Src subfamily of proteins, which are cytoplasmic (or non-receptor) PTKs. Lyn is expressed in B lymphocytes and myeloid cells. It exhibits both positive and negative regulatory roles in B cell receptor (BCR) signaling. Lyn, as well as Fyn and Blk, promotes B cell activation by phosphorylating ITAMs (immunoreceptor tyr activation motifs) in CD19 and in Ig components of BCR []. It negatively regulates signaling by its unique ability to phosphorylate ITIMs (immunoreceptor tyr inhibition motifs) in cell surface receptors like CD22 and CD5 []. Lyn also plays an important role in G-CSF receptor signaling by phosphorylating a variety of adaptor molecules []. Src kinases contain an N-terminal SH4 domain with a myristoylation site, followed by SH3 and SH2 domains, a tyr kinase domain, and a regulatory C-terminal region containing a conserved tyr. They are activated by autophosphorylation at the tyr kinase domain, but are negatively regulated by phosphorylation at the C-terminal tyr by Csk (C-terminal Src Kinase). The SH3 domain of Src kinases contributes to substrate recruitment by binding adaptor proteins/substrates, and regulation of kinase activity through an intramolecular interaction [, ].
Publication
First Author: Wang JB
Year: 1992
Journal: Brain Res Bull
Title: Strain comparisons and developmental profile of the delta subunit of the murine GABAA receptor.
Volume: 29
Issue: 1
Pages: 119-23
Publication
First Author: Qvartskhava N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase.
Volume: 112
Issue: 17
Pages: 5521-6
Publication
First Author: Peris L
Year: 2009
Journal: J Cell Biol
Title: Motor-dependent microtubule disassembly driven by tubulin tyrosination.
Volume: 185
Issue: 7
Pages: 1159-66
Publication
First Author: Barber DF
Year: 2006
Journal: J Immunol
Title: Class IB-phosphatidylinositol 3-kinase (PI3K) deficiency ameliorates IA-PI3K-induced systemic lupus but not T cell invasion.
Volume: 176
Issue: 1
Pages: 589-93
Publication
First Author: Gong Q
Year: 2001
Journal: J Exp Med
Title: Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell development.
Volume: 194
Issue: 4
Pages: 507-18
Publication
First Author: Li K
Year: 2014
Journal: Int J Clin Exp Pathol
Title: DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test.
Volume: 7
Issue: 10
Pages: 6486-92
Publication
First Author: Gong H
Year: 2014
Journal: J Exp Med
Title: Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin.
Volume: 211
Issue: 3
Pages: 579-91
Publication
First Author: Fan Y
Year: 2012
Journal: Nat Cell Biol
Title: Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.
Volume: 14
Issue: 10
Pages: 1046-56
Publication
First Author: Krajewska M
Year: 2008
Journal: Am J Pathol
Title: Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase.
Volume: 172
Issue: 5
Pages: 1312-24
Publication
First Author: Lobón-Iglesias MJ
Year: 2023
Journal: Nat Commun
Title: Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups.
Volume: 14
Issue: 1
Pages: 6669
Publication
First Author: Ng KJ
Year: 2022
Journal: Cell Rep
Title: Sox2 in the dermal papilla regulates hair follicle pigmentation.
Volume: 40
Issue: 3
Pages: 111100
Publication
First Author: Huynh H
Year: 2004
Journal: Nat Cell Biol
Title: Control of vesicle fusion by a tyrosine phosphatase.
Volume: 6
Issue: 9
Pages: 831-9
Publication
First Author: Koonpaew S
Year: 2004
Journal: J Biol Chem
Title: The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB.
Volume: 279
Issue: 12
Pages: 11229-35
Publication
First Author: Peissel B
Year: 2000
Journal: Mamm Genome
Title: Linkage disequilibrium and haplotype mapping of a skin cancer susceptibility locus in outbred mice.
Volume: 11
Issue: 11
Pages: 979-81
Publication
First Author: Harpur AG
Year: 1993
Journal: Immunol Lett
Title: A prominent natural H-2 Kd ligand is derived from protein tyrosine kinase JAK1.
Volume: 35
Issue: 3
Pages: 235-7
Publication
First Author: Novick D
Year: 1994
Journal: Cell
Title: The human interferon alpha/beta receptor: characterization and molecular cloning.
Volume: 77
Issue: 3
Pages: 391-400
Publication
First Author: Spence MJ
Year: 1995
Journal: Somat Cell Mol Genet
Title: Analysis of mutations in alleles of the fur gene from an endoprotease-deficient Chinese hamster ovary cell strain.
Volume: 21
Issue: 1
Pages: 1-18
Publication
First Author: Crawley SC
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.
Volume: 263
Issue: 3
Pages: 728-36
Publication
First Author: Ponder CA
Year: 2008
Journal: Behav Genet
Title: Rapid selection response for contextual fear conditioning in a cross between C57BL/6J and A/J: behavioral, QTL and gene expression analysis.
Volume: 38
Issue: 3
Pages: 277-91
Publication
First Author: Seruggia D
Year: 2020
Journal: Sci Rep
Title: Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression.
Volume: 10
Issue: 1
Pages: 15494
Publication
First Author: Roy A
Year: 2015
Journal: Cell Metab
Title: HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice.
Volume: 22
Issue: 2
Pages: 253-65
Publication
First Author: Beyer LA
Year: 2000
Journal: J Neurocytol
Title: Hair cells in the inner ear of the pirouette and shaker 2 mutant mice.
Volume: 29
Issue: 4
Pages: 227-40
Publication
First Author: Lyon MF
Year: 1988
Journal: J Hered
Title: Mouse globin gene nomenclature.
Volume: 79
Issue: 2
Pages: 93-5
Strain
Attribute String: mutant strain, coisogenic, spontaneous mutation
Publication
First Author: ARNESEN K
Year: 1955
Journal: Acta Endocrinol (Copenh)
Title: Constitutional difference in lipid content of adrenals in two strains of mice and their hybrids.
Volume: 18
Issue: 4
Pages: 396-401
Publication  
First Author: Taylor BA
Year: 1974
Journal: Genetics
Title: Chromosomal location and site of action of the adrenal lipid depletion gene of the mouse.
Volume: 77
Pages: s65 (Abstr.)
Publication
First Author: Masterson JC
Year: 2011
Journal: Am J Pathol
Title: CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling.
Volume: 179
Issue: 5
Pages: 2302-14
Publication
First Author: Rice RH
Year: 2009
Journal: J Invest Dermatol
Title: Distinguishing mouse strains by proteomic analysis of pelage hair.
Volume: 129
Issue: 9
Pages: 2120-5
Publication
First Author: Wu B
Year: 2010
Journal: J Invest Dermatol
Title: Mutations in sterol O-acyltransferase 1 (Soat1) result in hair interior defects in AKR/J mice.
Volume: 130
Issue: 11
Pages: 2666-8
Publication  
First Author: Arnesen K
Year: 1963
Journal: Acta Pathol Microbiol Scand
Title: The cytology of the adrenal cortex in mice with spontaneous adrenocortical lipid depletion.
Volume: 58
Pages: 212-218
Publication
First Author: Hai Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.
Volume: 38
Issue: 1
Pages: 83-91
Publication
First Author: Molne K
Year: 1968
Journal: Acta Pathol Microbiol Scand
Title: Spontaneous adrenocortical lipid depletion in mice. Relationship to general growth, degeneration of adrenal X zone, and maturation of seminiferous eptthelium.
Volume: 72
Issue: 4
Pages: 478-90
Publication
First Author: Molne K
Year: 1969
Journal: Acta Pathol Microbiol Scand
Title: Autoradiographic studies on the incorporation of H-uridine into the adrenal glands of mice with spontaneous adrenocortical lipid depletion. A comparison with C57B1 mice.
Volume: 77
Issue: 3
Pages: 369-78
Publication
First Author: Doering CH
Year: 1973
Journal: Biochem Genet
Title: Genetic and biochemical studies of the adrenal lipid depletion phenotype in mice.
Volume: 8
Issue: 1
Pages: 101-11
Publication  
First Author: Arnesen K
Year: 1974
Journal: Acta Pathol Microbiol Scand Suppl
Title: Adrenocortical lipid depletion and leukemia in mice.
Volume: Suppl 248
Pages: 15-9
Publication
First Author: Meiner VL
Year: 1998
Journal: J Biol Chem
Title: Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation.
Volume: 273
Issue: 2
Pages: 1064-9
Publication
First Author: Tiveron MC
Year: 2006
Journal: J Neurosci
Title: Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/CXCR4 signaling in the cortical subventricular zone/intermediate zone.
Volume: 26
Issue: 51
Pages: 13273-8
Allele  
Name: insulin II; Akita
Allele Type: Spontaneous
Publication
First Author: Weston CJ
Year: 2015
Journal: J Clin Invest
Title: Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Volume: 125
Issue: 2
Pages: 501-20
Publication
First Author: Marttila-Ichihara F
Year: 2017
Journal: FASEB J
Title: Amine oxidase activity regulates the development of pulmonary fibrosis.
Volume: 31
Issue: 6
Pages: 2477-2491
Publication
First Author: Jargaud V
Year: 2021
Journal: J Physiol Biochem
Title: Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity.
Volume: 77
Issue: 1
Pages: 141-154
Allele
Name: transgene insertion 13, Marcus Bosenberg
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication
First Author: Lavado A
Year: 2006
Journal: J Neurochem
Title: Ectopic expression of tyrosine hydroxylase in the pigmented epithelium rescues the retinal abnormalities and visual function common in albinos in the absence of melanin.
Volume: 96
Issue: 4
Pages: 1201-11
Strain
Attribute String: mutant strain
Publication
First Author: Ackroyd MR
Year: 2011
Journal: J Neurosci
Title: Fukutin-related protein alters the deposition of laminin in the eye and brain.
Volume: 31
Issue: 36
Pages: 12927-35
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, transgenic, mutant strain
Publication
First Author: Li W
Year: 2010
Journal: Cleft Palate Craniofac J
Title: Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.
Volume: 47
Issue: 6
Pages: 566-73
Allele
Name: neuroguidin, EIF4E binding protein; transgene insertion 2397E-1a3, Paul Overbeek
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: nucleoporin 35; transgene insertion 2383D-1a1a2, Paul Overbeek
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: Fanconi anemia, complementation group E; transgene insertion 2364E-2a2, Paul Overbeek
Allele Type: Transgenic
Attribute String: Null/knockout, Reporter
Allele
Name: ARB2 cotranscriptional regulator A; transgene insertion Tp, Nicolas Pilon
Allele Type: Transgenic
Attribute String: Hypomorph, Inserted expressed sequence
Genotype
Symbol: Soat1/Soat1
Background: AKR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fkrp/Fkrp
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true