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Search results 1101 to 1200 out of 1341 for Yap1

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Type Details Score
Publication
First Author: Zieman AG
Year: 2019
Journal: Hum Mol Genet
Title: Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.
Volume: 28
Issue: 13
Pages: 2255-2270
Publication  
First Author: Bertol JW
Year: 2022
Journal: Development
Title: TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells.
Volume: 149
Issue: 15
Publication
First Author: Lavado A
Year: 2013
Journal: Development
Title: Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.
Volume: 140
Issue: 16
Pages: 3323-34
Publication
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
Publication
First Author: Reginensi A
Year: 2013
Journal: PLoS Genet
Title: Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.
Volume: 9
Issue: 3
Pages: e1003380
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
Publication
First Author: Tanahashi H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of Lrp4 increases the incidence of microphthalmia.
Volume: 506
Issue: 3
Pages: 478-484
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Interaction Experiment
Description: ATXN3 deubiquitinates YAP1 to promote tumor growth.
Allele
Name: yes-associated protein 1; targeted mutation 1c, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready
Publication
First Author: Haemmerle M
Year: 2017
Journal: Nat Commun
Title: Platelets reduce anoikis and promote metastasis by activating YAP1 signaling.
Volume: 8
Issue: 1
Pages: 310
Protein
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 353  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication  
First Author: Kim YS
Year: 2022
Journal: Pharmaceutics
Title: PSME4 Degrades Acetylated YAP1 in the Nucleus of Mesenchymal Stem Cells.
Volume: 14
Issue: 8
Publication
First Author: Zhang L
Year: 2015
Journal: Curr Biol
Title: NDR functions as a physiological YAP1 kinase in the intestinal epithelium.
Volume: 25
Issue: 3
Pages: 296-305
Publication
First Author: Nimmakayala RK
Year: 2022
Journal: Cell Death Dis
Title: PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer.
Volume: 13
Issue: 10
Pages: 839
Publication
First Author: Kim JW
Year: 2022
Journal: Cell Rep
Title: Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer.
Volume: 41
Issue: 1
Pages: 111443
Publication
First Author: Zhuge R
Year: 2023
Journal: Cell Rep
Title: hCINAP regulates the differentiation of embryonic stem cells by regulating NEDD4 liquid-liquid phase-separation-mediated YAP1 activation.
Volume: 42
Issue: 1
Pages: 111935
Publication
First Author: Guo Y
Year: 2022
Journal: Cell Rep
Title: Opposing roles of ZEB1 in the cytoplasm and nucleus control cytoskeletal assembly and YAP1 activity.
Volume: 41
Issue: 1
Pages: 111452
Publication
First Author: Szulzewsky F
Year: 2020
Journal: Genes Dev
Title: Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Volume: 34
Issue: 15-16
Pages: 1051-1064
Publication
First Author: Jiang Y
Year: 2023
Journal: Cell Mol Life Sci
Title: Myeloid SENP3 deficiency protects mice from diet and age-induced obesity via regulation of YAP1 SUMOylation.
Volume: 81
Issue: 1
Pages: 4
Publication
First Author: Kim M
Year: 2023
Journal: Korean J Physiol Pharmacol
Title: PSME4 determines mesenchymal stem cell fate towards cardiac commitment through YAP1 degradation.
Volume: 27
Issue: 4
Pages: 407-416
Publication
First Author: Xia A
Year: 2022
Journal: Nat Cancer
Title: The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription.
Volume: 3
Issue: 2
Pages: 203-218
Publication
First Author: Zhou D
Year: 2009
Journal: Cancer Cell
Title: Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.
Volume: 16
Issue: 5
Pages: 425-38
Publication
First Author: Tremblay AM
Year: 2014
Journal: Cancer Cell
Title: The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.
Volume: 26
Issue: 2
Pages: 273-87
Publication
First Author: Mohamed AD
Year: 2018
Journal: Sci Rep
Title: Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma.
Volume: 8
Issue: 1
Pages: 15674
Publication      
First Author: Szulzewsky F
Year: 2022
Journal: Genes Dev
Title: Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice.
Publication
First Author: Komuro A
Year: 2003
Journal: J Biol Chem
Title: WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus.
Volume: 278
Issue: 35
Pages: 33334-41
Publication
First Author: Wang S
Year: 2023
Journal: Am J Cancer Res
Title: ATXN3 deubiquitinates YAP1 to promote tumor growth.
Volume: 13
Issue: 9
Pages: 4222-4234
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: yes-associated protein 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression  
Probe: MGI:3051329
Assay Type: Immunohistochemistry
Annotation Date: 2016-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:5763604
Age: embryonic day 3.5
Note: There was colocalization with Yap1 in trophectoderm cells.
Specimen Label: 3C
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7437533
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717117
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7437581
Age: embryonic day 10.5
Image: 1B/C
Note: Coexpressed with Yap1 in a subset of cells.
Specimen Label: 1B/C
Detected: true
Specimen Num: 1
Publication
First Author: Chen L
Year: 2010
Journal: Genes Dev
Title: Structural basis of YAP recognition by TEAD4 in the hippo pathway.
Volume: 24
Issue: 3
Pages: 290-300
Allele
Name: yes-associated protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Reporter
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
DO Term
GXD Expression
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7437618
Age: embryonic day 16.5
Image: 6D
Note: More positive cells were detected in the epithelial areas where Yap1 reduction was evident.
Specimen Label: 6D
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: 8B
Note: The overgrowth of the cortical hem was significantly suppressed by the Yap1 mutation.
Specimen Label: 8B
Detected: true
Specimen Num: 32
GXD Expression
Probe: MGI:7437533
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7437581
Age: embryonic day 10.5
Image: 1B/C
Note: Future pigmented retinal epithelium. Coexpressed with Yap1 in a subset of cells.
Specimen Label: 1B/C
Detected: true
Specimen Num: 1
Publication
First Author: Hoshino M
Year: 2006
Journal: J Cell Biol
Title: Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
Volume: 172
Issue: 4
Pages: 589-604
Publication
First Author: Veal EA
Year: 2003
Journal: J Biol Chem
Title: Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor.
Volume: 278
Issue: 33
Pages: 30896-904
Publication
First Author: Rosenbluh J
Year: 2012
Journal: Cell
Title: β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Volume: 151
Issue: 7
Pages: 1457-73
Allele
Name: yes-associated protein 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
GXD Expression
Probe: MGI:5697417
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7437616
Age: embryonic day 16.5
Image: 5G
Note: Partial disruption of expression in most, but not all, retinal areas without Yap1 expression at the apical surface.
Specimen Label: 5G
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7437609
Age: embryonic day 16.5
Image: 5E
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression.
Specimen Label: 5E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7438259
Age: embryonic day 16.5
Image: 5E
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression.
Specimen Label: 5E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3721110
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7438260
Age: embryonic day 16.5
Image: 5E
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression.
Specimen Label: 5E
Detected: true
Specimen Num: 3
Publication
First Author: Chen HI
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
Volume: 92
Issue: 17
Pages: 7819-23
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
GXD Expression
Probe: MGI:2674976
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859027
Pattern: Scattered
Stage: TS27
Assay Id: MGI:7437618
Age: postnatal day 0
Image: 6H/J
Note: Dramatic and widespread increase (25 fold) of positive cells occurred preferentially in the mutant epithelial area without Yap1 staining in both inner and outer neuroblastic layer.
Specimen Label: 6H/J
Detected: true
Specimen Num: 6
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ben Stanger
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence, Reporter
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ralf H Adams
Allele Type: Targeted
Attribute String: Conditional ready, Constitutively active, Inserted expressed sequence, Reporter
Strain
Attribute String: coisogenic, targeted mutation, mutant strain
GXD Expression
Probe: MGI:5697421
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7437614
Age: embryonic day 15.5
Image: 5F
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina.
Specimen Label: 5F
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5697421
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7437614
Age: embryonic day 15.5
Image: 5F
Note: The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina.
Specimen Label: 5F
Detected: true
Specimen Num: 1
GO Term
Strain
Attribute String: congenic, mutant strain, targeted mutation