Type |
Details |
Score |
Publication |
First Author: |
Zieman AG |
Year: |
2019 |
Journal: |
Hum Mol Genet |
Title: |
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. |
Volume: |
28 |
Issue: |
13 |
Pages: |
2255-2270 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertol JW |
Year: |
2022 |
Journal: |
Development |
Title: |
TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells. |
Volume: |
149 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lavado A |
Year: |
2013 |
Journal: |
Development |
Title: |
Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. |
Volume: |
140 |
Issue: |
16 |
Pages: |
3323-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu C |
Year: |
2013 |
Journal: |
Science |
Title: |
CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. |
Volume: |
342 |
Issue: |
6165 |
Pages: |
1518-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reginensi A |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e1003380 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scavuzzo MA |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3356 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanahashi H |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Deletion of Lrp4 increases the incidence of microphthalmia. |
Volume: |
506 |
Issue: |
3 |
Pages: |
478-484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cobellis G |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
Tagging genes with cassette-exchange sites. |
Volume: |
33 |
Issue: |
4 |
Pages: |
e44 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
ATXN3 deubiquitinates YAP1 to promote tumor growth. |
|
•
•
•
•
•
|
Allele |
Name: |
yes-associated protein 1; targeted mutation 1c, Mouse Biology Program, UC Davis |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Publication |
First Author: |
Haemmerle M |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. |
Volume: |
8 |
Issue: |
1 |
Pages: |
310 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
488
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
397
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
357
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
353
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
369
 |
Fragment?: |
false |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim YS |
Year: |
2022 |
Journal: |
Pharmaceutics |
Title: |
PSME4 Degrades Acetylated YAP1 in the Nucleus of Mesenchymal Stem Cells. |
Volume: |
14 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2015 |
Journal: |
Curr Biol |
Title: |
NDR functions as a physiological YAP1 kinase in the intestinal epithelium. |
Volume: |
25 |
Issue: |
3 |
Pages: |
296-305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmakayala RK |
Year: |
2022 |
Journal: |
Cell Death Dis |
Title: |
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer. |
Volume: |
13 |
Issue: |
10 |
Pages: |
839 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JW |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer. |
Volume: |
41 |
Issue: |
1 |
Pages: |
111443 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhuge R |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
hCINAP regulates the differentiation of embryonic stem cells by regulating NEDD4 liquid-liquid phase-separation-mediated YAP1 activation. |
Volume: |
42 |
Issue: |
1 |
Pages: |
111935 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Y |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Opposing roles of ZEB1 in the cytoplasm and nucleus control cytoskeletal assembly and YAP1 activity. |
Volume: |
41 |
Issue: |
1 |
Pages: |
111452 |
|
•
•
•
•
•
|
Publication |
First Author: |
Szulzewsky F |
Year: |
2020 |
Journal: |
Genes Dev |
Title: |
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis. |
Volume: |
34 |
Issue: |
15-16 |
Pages: |
1051-1064 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang Y |
Year: |
2023 |
Journal: |
Cell Mol Life Sci |
Title: |
Myeloid SENP3 deficiency protects mice from diet and age-induced obesity via regulation of YAP1 SUMOylation. |
Volume: |
81 |
Issue: |
1 |
Pages: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim M |
Year: |
2023 |
Journal: |
Korean J Physiol Pharmacol |
Title: |
PSME4 determines mesenchymal stem cell fate towards cardiac commitment through YAP1 degradation. |
Volume: |
27 |
Issue: |
4 |
Pages: |
407-416 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia A |
Year: |
2022 |
Journal: |
Nat Cancer |
Title: |
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription. |
Volume: |
3 |
Issue: |
2 |
Pages: |
203-218 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou D |
Year: |
2009 |
Journal: |
Cancer Cell |
Title: |
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. |
Volume: |
16 |
Issue: |
5 |
Pages: |
425-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tremblay AM |
Year: |
2014 |
Journal: |
Cancer Cell |
Title: |
The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation. |
Volume: |
26 |
Issue: |
2 |
Pages: |
273-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mohamed AD |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma. |
Volume: |
8 |
Issue: |
1 |
Pages: |
15674 |
|
•
•
•
•
•
|
Publication |
First Author: |
Szulzewsky F |
Year: |
2022 |
Journal: |
Genes Dev |
Title: |
Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Komuro A |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. |
Volume: |
278 |
Issue: |
35 |
Pages: |
33334-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2023 |
Journal: |
Am J Cancer Res |
Title: |
ATXN3 deubiquitinates YAP1 to promote tumor growth. |
Volume: |
13 |
Issue: |
9 |
Pages: |
4222-4234 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Allele |
Name: |
yes-associated protein 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3051329 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-04-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160464 |
Pattern: |
Not Specified |
Stage: |
TS04 |
Assay Id: |
MGI:5763604 |
Age: |
embryonic day 3.5 |
|
Note: |
There was colocalization with Yap1 in trophectoderm cells. |
Specimen Label: |
3C |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7437533 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717117 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7437581 |
Age: |
embryonic day 10.5 |
Image: |
1B/C |
Note: |
Coexpressed with Yap1 in a subset of cells. |
Specimen Label: |
1B/C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
Structural basis of YAP recognition by TEAD4 in the hippo pathway. |
Volume: |
24 |
Issue: |
3 |
Pages: |
290-300 |
|
•
•
•
•
•
|
Allele |
Name: |
yes-associated protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2674976 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859024 |
Pattern: |
Single cells |
Stage: |
TS24 |
Assay Id: |
MGI:7437618 |
Age: |
embryonic day 16.5 |
Image: |
6D |
Note: |
More positive cells were detected in the epithelial areas where Yap1 reduction was evident. |
Specimen Label: |
6D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6407030 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6416278 |
Age: |
embryonic day 15.5 |
Image: |
8B |
Note: |
The overgrowth of the cortical hem was significantly suppressed by the Yap1 mutation. |
Specimen Label: |
8B |
Detected: |
true |
Specimen Num: |
32 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7437533 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1667717 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:7437581 |
Age: |
embryonic day 10.5 |
Image: |
1B/C |
Note: |
Future pigmented retinal epithelium. Coexpressed with Yap1 in a subset of cells. |
Specimen Label: |
1B/C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoshino M |
Year: |
2006 |
Journal: |
J Cell Biol |
Title: |
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73. |
Volume: |
172 |
Issue: |
4 |
Pages: |
589-604 |
|
•
•
•
•
•
|
Publication |
First Author: |
Veal EA |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor. |
Volume: |
278 |
Issue: |
33 |
Pages: |
30896-904 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenbluh J |
Year: |
2012 |
Journal: |
Cell |
Title: |
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. |
Volume: |
151 |
Issue: |
7 |
Pages: |
1457-73 |
|
•
•
•
•
•
|
Allele |
Name: |
yes-associated protein 1; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5697417 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859024 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:7437616 |
Age: |
embryonic day 16.5 |
Image: |
5G |
Note: |
Partial disruption of expression in most, but not all, retinal areas without Yap1 expression at the apical surface. |
Specimen Label: |
5G |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3721110 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859024 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:7437609 |
Age: |
embryonic day 16.5 |
Image: |
5E |
Note: |
The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3721110 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859024 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:7438259 |
Age: |
embryonic day 16.5 |
Image: |
5E |
Note: |
The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3721110 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859024 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:7438260 |
Age: |
embryonic day 16.5 |
Image: |
5E |
Note: |
The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. |
Specimen Label: |
5E |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen HI |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. |
Volume: |
92 |
Issue: |
17 |
Pages: |
7819-23 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2674976 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859027 |
Pattern: |
Scattered |
Stage: |
TS27 |
Assay Id: |
MGI:7437618 |
Age: |
postnatal day 0 |
Image: |
6H/J |
Note: |
Dramatic and widespread increase (25 fold) of positive cells occurred preferentially in the mutant epithelial area without Yap1 staining in both inner and outer neuroblastic layer. |
Specimen Label: |
6H/J |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Allele |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ben Stanger |
Allele Type: |
Targeted |
Attribute String: |
Inducible, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ralf H Adams |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Constitutively active, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation, mutant strain |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5697421 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7437614 |
Age: |
embryonic day 15.5 |
Image: |
5F |
Note: |
The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina. |
Specimen Label: |
5F |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5697421 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7437614 |
Age: |
embryonic day 15.5 |
Image: |
5F |
Note: |
The area showing a break in the presumptive outer limiting membrane correlated with a decrease in Yap1 expression. There was partial fusion when the duplicated retina abutted the original retina. |
Specimen Label: |
5F |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|