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Search results 11801 to 11900 out of 17714 for Proc

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Type Details Score
Publication
25002511 | J:212261
First Author: Qu Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner.
Volume: 111
Issue: 29
Pages: E2996-3004
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28446616 | J:242217
First Author: Harder JM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.
Volume: 114
Issue: 19
Pages: E3839-E3848
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18272502 | J:132180
First Author: Du M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model.
Volume: 105
Issue: 6
Pages: 2064-9
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Publication
20080688 | J:156532
First Author: Hung KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Volume: 107
Issue: 4
Pages: 1565-70
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Publication
18621715 | J:140423
First Author: Seidler B
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.
Volume: 105
Issue: 29
Pages: 10137-42
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11805341 | J:73988
First Author: Jasmin L
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline.
Volume: 99
Issue: 2
Pages: 1029-34
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8290590 | J:16489
First Author: Ioffe E
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.
Volume: 91
Issue: 2
Pages: 728-32
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Publication
32198206 | J:290058
First Author: Polina I
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.
Volume: 117
Issue: 14
Pages: 7990-8000
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Publication
21555585 | J:171889
First Author: Lee AH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.
Volume: 108
Issue: 21
Pages: 8885-90
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Publication
21555558 | J:171899
First Author: Fox R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Volume: 108
Issue: 21
Pages: 8779-84
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Publication
21383153 | J:170095
First Author: Urosevic J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome.
Volume: 108
Issue: 12
Pages: 5015-20
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Publication
24711431 | J:208854
First Author: McFadden DG
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer.
Volume: 111
Issue: 16
Pages: E1600-9
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Publication
15067126 | J:89602
First Author: Kimura Y
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages.
Volume: 101
Issue: 16
Pages: 6015-20
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12754375 | J:83616
First Author: Sommer G
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.
Volume: 100
Issue: 11
Pages: 6706-11
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18216268 | J:131856
First Author: Johnson TM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence.
Volume: 105
Issue: 4
Pages: 1215-20
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23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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17626182 | J:126551
First Author: Liu X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.
Volume: 104
Issue: 29
Pages: 12111-6
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10805794 | J:111370
First Author: Amson R
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice.
Volume: 97
Issue: 10
Pages: 5346-50
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10823907 | J:62721
First Author: Ferguson DO
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.
Volume: 97
Issue: 12
Pages: 6630-3
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17056717 | J:115637
First Author: Giuriato S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.
Volume: 103
Issue: 44
Pages: 16266-71
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23236145 | J:192543
First Author: Leonova KI
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs.
Volume: 110
Issue: 1
Pages: E89-98
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21282604 | J:169071
First Author: Yoshida T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus.
Volume: 108
Issue: 7
Pages: 3059-64
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24191036 | J:202980
First Author: Liu J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.
Volume: 110
Issue: 47
Pages: 18832-7
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12538878 | J:81844
First Author: Wang L
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice.
Volume: 100
Issue: 3
Pages: 1393-8
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21383171 | J:171244
First Author: Mukhopadhyay B
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver.
Volume: 108
Issue: 15
Pages: 6323-8
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12235369 | J:79501
First Author: Bergo MO
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.
Volume: 99
Issue: 20
Pages: 13049-54
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17079494 | J:117109
First Author: Liu B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas.
Volume: 103
Issue: 46
Pages: 17202-7
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12574514 | J:111586
First Author: Storm EE
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain.
Volume: 100
Issue: 4
Pages: 1757-62
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16682639 | J:110227
First Author: Emery B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination.
Volume: 103
Issue: 20
Pages: 7859-64
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21383142 | J:170098
First Author: Gachon F
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activity.
Volume: 108
Issue: 12
Pages: 4794-9
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12552126 | J:81834
First Author: Finck BN
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.
Volume: 100
Issue: 3
Pages: 1226-31
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Publication
22647601 | J:185518
First Author: Zhang MA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way.
Volume: 109
Issue: 24
Pages: 9505-10
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33229553 | J:299214
First Author: Yueh MF
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease.
Volume: 117
Issue: 49
Pages: 31259-31266
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12195019 | J:78908
First Author: Lee Y
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue.
Volume: 99
Issue: 18
Pages: 11848-53
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10377439 | J:56056
First Author: Leone TC
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders.
Volume: 96
Issue: 13
Pages: 7473-8
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31641069 | J:281574
First Author: Cahill LS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.
Volume: 116
Issue: 45
Pages: 22710-22720
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20837544 | J:164682
First Author: Cao JL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons.
Volume: 107
Issue: 39
Pages: 17011-6
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8102800 | J:14491
First Author: Dollé P
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.
Volume: 90
Issue: 16
Pages: 7666-70
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24938781 | J:212185
First Author: Petchey LK
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.
Volume: 111
Issue: 26
Pages: 9515-20
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11381139 | J:69874
First Author: Keith B
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt.
Volume: 98
Issue: 12
Pages: 6692-7
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12432092 | J:80520
First Author: Vivian JL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells.
Volume: 99
Issue: 24
Pages: 15542-7
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9689088 | J:49084
First Author: Weinstein M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.
Volume: 95
Issue: 16
Pages: 9378-83
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11226283 | J:135466
First Author: Sullivan TJ
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation.
Volume: 98
Issue: 5
Pages: 2587-92
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30478038 | J:269489
First Author: Wang Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance.
Volume: 115
Issue: 50
Pages: E11827-E11836
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20733081 | J:164383
First Author: Pan W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear.
Volume: 107
Issue: 36
Pages: 15798-803
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14668430 | J:88147
First Author: Hirashima M
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal-fetal interface in the mouse placenta.
Volume: 100
Issue: 26
Pages: 15637-42
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21402950 | J:171233
First Author: Fei M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection.
Volume: 108
Issue: 13
Pages: 5360-5
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11792862 | J:73981
First Author: Kline DD
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha.
Volume: 99
Issue: 2
Pages: 821-6
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22308491 | J:182020
First Author: Boboila C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1).
Volume: 109
Issue: 7
Pages: 2473-8
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20133615 | J:157574
First Author: Rucci F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.
Volume: 107
Issue: 7
Pages: 3024-9
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20133803 | J:157537
First Author: Boboila C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
Volume: 107
Issue: 7
Pages: 3034-9
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10339587 | J:55124
First Author: Idris AH
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The natural killer gene complex genetic locus Chok encodes Ly-49D, a target recognition receptor that activates natural killing.
Volume: 96
Issue: 11
Pages: 6330-5
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17664423 | J:123471
First Author: Zhao Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum.
Volume: 104
Issue: 32
Pages: 13182-6
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9391088 | J:44649
First Author: Zákány J
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.
Volume: 94
Issue: 25
Pages: 13695-700
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9177207 | J:40971
First Author: Vittet D
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies.
Volume: 94
Issue: 12
Pages: 6273-8
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8421714 | J:50848
First Author: Kulkarni AB
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
Volume: 90
Issue: 2
Pages: 770-4
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10611318 | J:59084
First Author: Glick A
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Defects in transforming growth factor-beta signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes.
Volume: 96
Issue: 26
Pages: 14949-54
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24812125 | J:211038
First Author: Kawasaki K
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.
Volume: 111
Issue: 21
Pages: 7723-8
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23064636 | J:190711
First Author: Freimuth J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus.
Volume: 109
Issue: 44
Pages: 18042-7
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9405645 | J:45075
First Author: Schwarz M
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.
Volume: 94
Issue: 26
Pages: 14518-23
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17360455 | J:120065
First Author: Khoo CM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.
Volume: 104
Issue: 10
Pages: 3931-6
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20616008 | J:162411
First Author: Kitamura T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.
Volume: 107
Issue: 29
Pages: 13063-8
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10359808 | J:55723
First Author: Wang M
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Matrix metalloproteinase deficiencies affect contact hypersensitivity: stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response.
Volume: 96
Issue: 12
Pages: 6885-9
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16439483 | J:106076
First Author: Mantena SR
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: C/EBPbeta is a critical mediator of steroid hormone-regulated cell proliferation and differentiation in the uterine epithelium and stroma.
Volume: 103
Issue: 6
Pages: 1870-5
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11070092 | J:125476
First Author: Krebs CJ
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors.
Volume: 97
Issue: 23
Pages: 12816-21
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16006513 | J:100184
First Author: Luo J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.
Volume: 102
Issue: 29
Pages: 10238-43
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19470463 | J:151903
First Author: Fernandez-Marcos PJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-kappaB activation and invasive prostate carcinoma.
Volume: 106
Issue: 31
Pages: 12962-7
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22891331 | J:188576
First Author: Fenton TR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
Volume: 109
Issue: 35
Pages: 14164-9
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16672372 | J:110098
First Author: Ji H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.
Volume: 103
Issue: 20
Pages: 7817-22
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22586120 | J:184756
First Author: Huillard E
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy.
Volume: 109
Issue: 22
Pages: 8710-5
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26884185 | J:231005
First Author: Lissanu Deribe Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Volume: 113
Issue: 9
Pages: E1296-305
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9618520 | J:48081
First Author: Winter DB
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2.
Volume: 95
Issue: 12
Pages: 6953-8
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9096356 | J:39399
First Author: Narayanan L
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2.
Volume: 94
Issue: 7
Pages: 3122-7
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9560238 | J:47642
First Author: Kawate H
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes.
Volume: 95
Issue: 9
Pages: 5116-20
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18832169 | J:143449
First Author: Kucherlapati MH
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.
Volume: 105
Issue: 40
Pages: 15493-8
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7753829 | J:25200
First Author: Oshima M
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene.
Volume: 92
Issue: 10
Pages: 4482-6
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29078383 | J:257262
First Author: Xue X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Volume: 114
Issue: 45
Pages: E9608-E9617
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Publication
19033191 | J:142249
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