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Search results 1201 to 1300 out of 1411 for Bmal1

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Type Details Score
HT Experiment
E-GEOD-29664 | DNA microarray analysis and functional profile of pituitary transcriptome under core-clock protein BMAL1 control
Series Id: GSE29664
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE266410 | Lung single cell RNA sequencing of hepatic Bmal1 and Hif1a deficient mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE255474 | Characterisation of the epidermal diurnal transcriptome of mice with K14-Cre-driven Bmal1 knockout
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
23337503 | -
First Author: Ma YT
Year: 2013
Journal: Biochem Biophys Res Commun
Title: O-GlcNAcylation of BMAL1 regulates circadian rhythms in NIH3T3 fibroblasts.
Volume: 431
Issue: 3
Pages: 382-7
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Publication
19330005 | -
First Author: Tamaru T
Year: 2009
Journal: Nat Struct Mol Biol
Title: CK2alpha phosphorylates BMAL1 to regulate the mammalian clock.
Volume: 16
Issue: 4
Pages: 446-8
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HT Sample
GSM5917829
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917830
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917831
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917832
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917833
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917834
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917835
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917836
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917837
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917838
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917839
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917840
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917841
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917842
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917843
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917844
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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HT Sample
GSM5917845
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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HT Sample
GSM5917846
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: gastrocnemius muscle
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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HT Sample
GSM5917865
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917866
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917867
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 0
Curation Status: Curated
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HT Sample
GSM5917868
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917869
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917870
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 4
Curation Status: Curated
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HT Sample
GSM5917871
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917872
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917873
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 8
Curation Status: Curated
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HT Sample
GSM5917874
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917875
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917876
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 12
Curation Status: Curated
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HT Sample
GSM5917877
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917878
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917879
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 16
Curation Status: Curated
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HT Sample
GSM5917880
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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HT Sample
GSM5917881
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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HT Sample
GSM5917882
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal week 8-12
Stage: 28
Structure . Name: liver
Notes: wild type tissue (mouse carries Cre transgenes but no Bmal1 allele); tissue isolated at Zeitgeber time (ZT) 20
Curation Status: Curated
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Allele
Bmal1<tm1Saco> | MGI:7531719
Name: basic helix-loop-helix ARNT like 1; targeted mutation 1, Paolo Sassone-Corsi
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
11875063 | -
First Author: Eide EJ
Year: 2002
Journal: J Biol Chem
Title: The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon.
Volume: 277
Issue: 19
Pages: 17248-54
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Publication
30683868 | -
First Author: Zheng X
Year: 2019
Journal: Cell Death Dis
Title: RAE1 promotes BMAL1 shuttling and regulates degradation and activity of CLOCK: BMAL1 heterodimer.
Volume: 10
Issue: 2
Pages: 62
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Publication
20718447 | J:166373
First Author: Noguchi T
Year: 2010
Journal: Biochemistry
Title: Dual-color luciferase mouse directly demonstrates coupled expression of two clock genes.
Volume: 49
Issue: 37
Pages: 8053-61
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HT Experiment
E-MTAB-3428 | Transcriptome profiling of Bma1 knock out mouse by RNASeq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Tg(Bmal1-cat,-luc*)1Shige | MGI:7520810
Name: transgene insertion 1, Shigenobu Shibata
Allele Type: Transgenic
Attribute String: Conditional ready, Reporter
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Genotype
Genotype
Symbol: Bmal1/Bmal1
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
19591933 | -
First Author: Mishra A
Year: 2009
Journal: Neurobiol Dis
Title: UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27.
Volume: 36
Issue: 1
Pages: 26-34
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Protein Domain
IPR017134 | UBE3A
Type: Family
Description: UBE3A (also known as E6-AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. It regulates cell proliferation by promoting proteasomal degradation of p27 []. It can also serve as a molecular circadian clock through regulating the BMAL1 transcription factor [].
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HT Experiment
GSE230078 | Targeting the intestinal circadian clock by meal timing ameliorates gastrointestinal inflammation
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6147216 | B6.Cg-Tg(Bmal1-cat,-luc*)1Shige/ShigeRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Tg(ACTA1-cre)79Jme/?
Background: involves: C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE199061 | Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and delta-RRE Liver Transcriptomes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE197455 | Interaction of muscle and liver circadian clocks on the transcriptome
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-MTAB-13320 | Single cell sequencing of fibroblast-like synoviocytes (FLS) isolated from hind paws of Col6a1-cre Bmal1-flox PER2::LUC mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-73552 | Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver [RNASeq]
Series Id: GSE73552
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Tg(ACTA1-cre)79Jme/? Tg(Alb1-cre)7Gsc/?
Background: involves: C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-35026 | Expression data in inguinal adipose tissue at different circadian times
Series Id: GSE35026
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE220864 | Reprogramming of rhythmic liver metabolism by intestine clock
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Krt14/Krt14<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE197726 | Interrogating the diurnal transcriptome of the muscle autonomous clock in vivo
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE158600 | Impact of circadian time, feeding-fasting rhythm and the autonomous clock on the transcriptome
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Syt10/Syt10<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Syt10/Syt10<+> Tg(ACTA1-cre)79Jme/?
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-GEOD-39978 | Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals [RNA-seq]
Series Id: GSE39978
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-14006 | Expression profiling of Bmal mutant dorsal skin at telogen of hair follicle cycling
Series Id: GSE14006
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-13579 | Expression profiling of Clock mutant dorsal skin at telogen
Series Id: GSE13579
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Krt14/Krt14<+> Syt10/Syt10<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE240710 | Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology [4 mouse lines]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
30782483 | J:291806
First Author: Sun S
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Sirt6 deacetylase activity regulates circadian rhythms via Per2.
Volume: 511
Issue: 2
Pages: 234-238
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Protein
O08759
Organism: Mus musculus/domesticus
Length: 870  
Fragment?: false
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Protein
Q5DTH1
Organism: Mus musculus/domesticus
Length: 906  
Fragment?: true
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HT Experiment
GSE229550 | Class 3 PI3K participates in nuclear gene transcription and co-activates the circadian clock to promote de novo purine synthesis [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11207387 | J:67618
First Author: Okano T
Year: 2001
Journal: Neurosci Lett
Title: Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication.
Volume: 300
Issue: 2
Pages: 111-4
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Publication
21874017 | J:179782
First Author: Valnegri P
Year: 2011
Journal: Nat Neurosci
Title: A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα.
Volume: 14
Issue: 10
Pages: 1293-301
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Publication
20534529 | J:161386
First Author: Yin L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
Volume: 107
Issue: 25
Pages: 11614-9
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Publication
17476214 | J:122764
First Author: Liu C
Year: 2007
Journal: Nature
Title: Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism.
Volume: 447
Issue: 7143
Pages: 477-81
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Publication
10640708 | J:60430
First Author: Michaud JL
Year: 2000
Journal: Mech Dev
Title: ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus.
Volume: 90
Issue: 2
Pages: 253-61
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Publication
22215614 | J:322674
First Author: Beaulé C
Year: 2011
Journal: J Biol Rhythms
Title: The acetyltransferase Clock is dispensable for circadian aftereffects in mice.
Volume: 26
Issue: 6
Pages: 561-4
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Publication
33287957 | J:347526
   
First Author: Crespo M
Year: 2020
Journal: Elife
Title: Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism.
Volume: 9
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Publication
23791176 | J:200008
First Author: Chang HC
Year: 2013
Journal: Cell
Title: SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging.
Volume: 153
Issue: 7
Pages: 1448-60
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Publication
26611104 | J:232818
First Author: Zhu B
Year: 2015
Journal: Mol Cell
Title: Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading.
Volume: 60
Issue: 5
Pages: 769-783
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Publication
28380384 | J:256753
First Author: Krishnaiah SY
Year: 2017
Journal: Cell Metab
Title: Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.
Volume: 25
Issue: 4
Pages: 961-974.e4
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Publication
17553428 | J:267124
First Author: Cheng HY
Year: 2007
Journal: Neuron
Title: microRNA modulation of circadian-clock period and entrainment.
Volume: 54
Issue: 5
Pages: 813-29
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Publication
29186676 | J:269809
First Author: Aggarwal A
Year: 2017
Journal: Cell Rep
Title: The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.
Volume: 21
Issue: 9
Pages: 2367-2375
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Publication
30789342 | J:275130
   
First Author: Hodge BA
Year: 2019
Journal: Elife
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