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Search results 1201 to 1300 out of 8285 for C2

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0.022s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
531691 | HECW2
Type: gene
Organism: cattle
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Gene
100685500 | HECW2
Type: gene
Organism: dog, domestic
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Gene
100858216 | ATP5G2
Type: gene
Organism: chicken
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Gene
420774 | HECW1
Type: gene
Organism: chicken
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Gene
424050 | HECW2
Type: gene
Organism: chicken
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Gene
100150269 | hecw2a
Type: gene
Organism: zebrafish
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Gene
100331355 | hecw2b
Type: gene
Organism: zebrafish
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Gene
563730 | hecw1b
Type: gene
Organism: zebrafish
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Gene
697155 | HECW2
Type: gene
Organism: macaque, rhesus
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Gene
701331 | HECW1
Type: gene
Organism: macaque, rhesus
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Gene
100170498 | hecw1
Type: gene
Organism: frog, western clawed
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Gene
108709830 | smarcc2.S
Type: gene
Organism: frog, African clawed
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Gene
108711193 | dnajc2.L
Type: gene
Organism: frog, African clawed
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Gene
108717181 | atp6v1c2.L
Type: gene
Organism: frog, African clawed
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Gene
108718244 | atp6v1c2.S
Type: gene
Organism: frog, African clawed
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Gene
414559 | dnajc2.S
Type: gene
Organism: frog, African clawed
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Gene
443822 | smarcc2.L
Type: gene
Organism: frog, African clawed
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Gene
444774 | slc35c2.S
Type: gene
Organism: frog, African clawed
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Publication
25042851 | -
First Author: Lu K
Year: 2014
Journal: Cell
Title: Autophagic clearance of polyQ proteins mediated by ubiquitin-Atg8 adaptors of the conserved CUET protein family.
Volume: 158
Issue: 3
Pages: 549-63
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Publication
27769858 | -
First Author: Deshar R
Year: 2016
Journal: Biochem Biophys Res Commun
Title: CC2D1A and CC2D1B regulate degradation and signaling of EGFR and TLR4.
Volume: 480
Issue: 2
Pages: 280-287
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Publication
19423080 | -
First Author: Hadjighassem MR
Year: 2009
Journal: Biol Psychiatry
Title: Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression.
Volume: 66
Issue: 3
Pages: 214-22
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Protein Domain
IPR039725 | CC2D1A/B
Type: Family
Description: This entry includes coiled-coil and C2 domain-containing protein 1A/B (CC2D1A/B, also known as Freud-1/2). CC2D1A is involved in many pathways, including nuclear factor kappaB, PDK1/Akt, cAMP/PKA, Notch and bone morphogenetic protein []. It is a calcium-regulated repressor of serotonine receptor 5-HT1A and dopamine-D2 receptor expression [, ]. CC2D1B binds to the 5-HT1A DRE and represses the human 5-HT1A receptor gene to regulate its expression in non-serotonergic cells and neurons [].CC2D1A and CC2D1B have also been shown to interact with the CHMP4 family of proteins, the major subunit of the ESCRT-III complex. They may regulate degradation and signaling of EGFR and TLR4 [].CC2D1A and CC2D1B share conserved domains, including several DM14 domains that are specific to this protein family, a C-terminal helix-loop-helix domain, and a C2 domain. The CC2D1A C2 domain is thought to be calcium insensitive and it lacks several acidic residues that mediate calcium binding of the PKC C2 domain. In addition, it contains a poly-basic insert that is not present in calcium-dependent C2 domains and may function as a nuclear localization signal []. The CC2D1B C2 domain appears to be essential for its DNA binding and repressor function; it may mediate protein-protein interactions []. Mutations in the CC2D1A gene has been linked to nonsyndromic mental retardation [, ].
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Protein
Q8C6N3
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
Q80U57
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
P60191
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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Protein
Q7TPL9
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
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Protein
Q9CYR4
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
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Protein
A0A1B0GRL5
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
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Protein
F7BG02
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
E9QA77
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: false
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Protein
V9GX86
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Protein
V9GWY2
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Protein
B7ZCP7
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: true
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Protein
A0A1W2P6J3
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A0G2JFZ0
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
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Protein
B7ZCP8
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
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Protein
D3Z5V2
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
Q14BY7
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: false
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Protein
A4FUQ0
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: true
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Protein
Q8CEQ2
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: false
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Publication
23773997 | -
First Author: Lalani SR
Year: 2013
Journal: Hum Mol Genet
Title: MCTP2 is a dosage-sensitive gene required for cardiac outflow tract development.
Volume: 22
Issue: 21
Pages: 4339-48
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Publication
14756806 | -
First Author: Lemonde S
Year: 2004
Journal: J Neurochem
Title: Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene.
Volume: 88
Issue: 4
Pages: 857-68
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Protein
Q8CFW7-2
Organism: Mus musculus/domesticus
Length: 1584  
Fragment?: false
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Protein
Q8VCX2
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Protein
Q5GMG8
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Protein
A0A0U1RP80
Organism: Mus musculus/domesticus
Length: 48  
Fragment?: true
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Protein
Q5GMG7
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
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Protein
A2A5A3
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
Q5GMG9
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: true
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Protein
A0A0U1RNH8
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Publication
22164291 | -
First Author: Mishra RR
Year: 2011
Journal: PLoS One
Title: A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells.
Volume: 6
Issue: 12
Pages: e28433
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Protein
A0A0U1RNH9
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Protein
Q5GMG6
Organism: Mus musculus/domesticus
Length: 58  
Fragment?: true
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Protein
A0A087WQB5
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
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Protein
Q5GMH1
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
A0A0U1RNT0
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: true
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Protein
E0CYZ1
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: false
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Protein
A0A087WQW4
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: true
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Allele
Col1a1<tm1(hs1473-PITX1)Smun> | MGI:5529077
Name: collagen, type I, alpha 1; targeted mutation 1, Stefan Mundlos
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Col1a1<tm2(tetO-IDH2*R140Q)Ppp> | MGI:5617498
Name: collagen, type I, alpha 1; targeted mutation 2, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Allele
Col1a1<tm1.1(tetO-IDH2*R140Q)Nbar> | MGI:5695652
Name: collagen, type I, alpha 1; targeted mutation 1.1, Nabeel Bardeesy
Allele Type: Targeted
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Col1a1<tm2.1(tetO-IDH2*R172K)Nbar> | MGI:5695654
Name: collagen, type I, alpha 1; targeted mutation 2.1, Nabeel Bardeesy
Allele Type: Targeted
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Col1a1<tm3(CAG-IDH2*R172K)Nbar> | MGI:5695656
Name: collagen, type I, alpha 1; targeted mutation 3, Nabeel Bardeesy
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Col1a1<tm3(tetO-Braf-rs1)Ppp> | MGI:5763653
Name: collagen, type I, alpha 1; targeted mutation 3, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Allele
Col1a1<tm4(tetO-Braf-rs1)Ppp> | MGI:5763654
Name: collagen, type I, alpha 1; targeted mutation 4, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Allele
Col1a1<tm5(tetO-Braf-rs1)Ppp> | MGI:5763655
Name: collagen, type I, alpha 1; targeted mutation 5, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Allele
C2cd2<+> | MGI:2441394
   
Name: C2 calcium-dependent domain containing 2; wild type
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Allele
Tc2n<+> | MGI:3049036
   
Name: tandem C2 domains, nuclear; wild type
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Allele
Rph3al<+> | MGI:3049474
   
Name: rabphilin 3A-like (without C2 domains); wild type
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Allele
C2cd2l<+> | MGI:3049921
   
Name: C2 calcium-dependent domain containing 2-like; wild type
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Allele
Mctp1<+> | MGI:3605680
 
Name: multiple C2 domains, transmembrane 1; wild type
Allele Type: Not Specified
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Allele
C2cd4a<+> | MGI:3659437
 
Name: C2 calcium-dependent domain containing 4A; wild type
Allele Type: Not Specified
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Allele
Mctp2<+> | MGI:3691330
 
Name: multiple C2 domains, transmembrane 2; wild type
Allele Type: Not Specified
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Allele
C2cd3<+> | MGI:3761140
 
Name: C2 calcium-dependent domain containing 3; wild type
Allele Type: Not Specified
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Allele
C2cd4b<+> | MGI:3810553
 
Name: C2 calcium-dependent domain containing 4B; wild type
Allele Type: Not Specified
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Allele
C2cd4c<+> | MGI:3810554
 
Name: C2 calcium-dependent domain containing 4C; wild type
Allele Type: Not Specified
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Allele
C2cd3<hty> | MGI:3836402
 
Name: C2 calcium-dependent domain containing 3; hearty
Allele Type: Chemically induced (ENU)
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Allele
C2cd4d<+> | MGI:4361487
 
Name: C2 calcium-dependent domain containing 4D; wild type
Allele Type: Not Specified
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Publication
- | J:185113
 
First Author: Peters J
Year: 1986
Journal: Mouse News Lett
Title: Analysis of Globin Gene Mutations Induced in Male Mice by Ethylnitrosourea
Volume: 76
Pages: 74
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Allele
C2cd5<+> | MGI:5447150
 
Name: C2 calcium-dependent domain containing 5; wild type
Allele Type: Not Specified
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Genotype
Genotype
Symbol: Hba/Hba
Background: involves: C3H/HeH
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
E-MTAB-3640 | Comparison of neonatal and adult lung gene expression
 
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-MEXP-3495 | Transcription profiling by array of limb buds from Gli3 mutant mouse embryos
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Domain
IPR020320 | Swinepox_virus_C2
Type: Family
Description: This entry is represented by Swinepox virus, C2; it is a family of uncharacterised viral proteins.
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Protein
Q9R0N9
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
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Publication
33492421 | J:302207
First Author: Mousavy Gharavy SN
Year: 2021
Journal: Diabetologia
Title: Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
Volume: 64
Issue: 4
Pages: 850-864
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Protein
P40749
Organism: Mus musculus/domesticus
Length: 425  
Fragment?: false
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Protein
Q920N7
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
Q920M7
Organism: Mus musculus/domesticus
Length: 470  
Fragment?: false
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Protein
Q7TN84
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
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Protein
Q571C5
Organism: Mus musculus/domesticus
Length: 499  
Fragment?: true
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Protein
A0A0N4SVG2
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
A0A1L1SVE7
Organism: Mus musculus/domesticus
Length: 838  
Fragment?: false
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Protein
A0A140LJ89
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: true
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Protein
A0A0N4SV78
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
Q14AG7
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
B7ZP31
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
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Publication
25096995 | -
First Author: Xu S
Year: 2014
Journal: Mol Cell Proteomics
Title: Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migration.
Volume: 13
Issue: 11
Pages: 2986-3000
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Publication
26826102 | J:241103
First Author: Oaks AW
Year: 2017
Journal: Cereb Cortex
Title: Cc2d1a Loss of Function Disrupts Functional and Morphological Development in Forebrain Neurons Leading to Cognitive and Social Deficits.
Volume: 27
Issue: 2
Pages: 1670-1685
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Publication
24163370 | -
First Author: Lu L
Year: 2013
Journal: J Biol Chem
Title: The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.
Volume: 288
Issue: 50
Pages: 35637-50
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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