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Search results 1201 to 1300 out of 1952 for Cdkn2a

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Type Details Score
Publication
28074012 | J:259463
 
First Author: Gamell C
Year: 2017
Journal: Sci Signal
Title: Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer.
Volume: 10
Issue: 461
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Publication
35354467 | J:332832
First Author: Limberger T
Year: 2022
Journal: Mol Cancer
Title: KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.
Volume: 21
Issue: 1
Pages: 89
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Publication
31915377 | J:290070
First Author: Su J
Year: 2020
Journal: Nature
Title: TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1.
Volume: 577
Issue: 7791
Pages: 566-571
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Publication
18037485 | J:349132
First Author: Ko RM
Year: 2008
Journal: Leuk Res
Title: Roles of p15Ink4b and p16Ink4a in myeloid differentiation and RUNX1-ETO-associated acute myeloid leukemia.
Volume: 32
Issue: 7
Pages: 1101-11
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Publication
22052106 | J:320501
First Author: DiNorcia J
Year: 2012
Journal: J Gastrointest Surg
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Volume: 16
Issue: 1
Pages: 104-12; discussion 112
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Publication
14500367 | J:95538
First Author: O'Hagan RC
Year: 2003
Journal: Cancer Res
Title: Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma.
Volume: 63
Issue: 17
Pages: 5352-6
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36131018 | J:335416
First Author: Karras P
Year: 2022
Journal: Nature
Title: A cellular hierarchy in melanoma uncouples growth and metastasis.
Volume: 610
Issue: 7930
Pages: 190-198
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Publication
11839803 | J:74623
First Author: Russell JL
Year: 2002
Journal: Mol Cell Biol
Title: ARF differentially modulates apoptosis induced by E2F1 and Myc.
Volume: 22
Issue: 5
Pages: 1360-8
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Publication
24691445 | J:212766
First Author: Rielland M
Year: 2014
Journal: J Clin Invest
Title: Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
Volume: 124
Issue: 5
Pages: 2125-35
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Publication
29248457 | J:258268
First Author: Zolghadri Y
Year: 2018
Journal: Am J Pathol
Title: Malnutrition in Pancreatic Ductal Adenocarcinoma (PDA): Dietary Pancreatic Enzymes Improve Short-Term Health but Stimulate Tumor Growth.
Volume: 188
Issue: 3
Pages: 616-626
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Publication
26438693 | J:226535
First Author: Ocal O
Year: 2015
Journal: Dis Model Mech
Title: A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
Volume: 8
Issue: 10
Pages: 1201-11
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Publication
33244070 | J:299705
First Author: Layeghi-Ghalehsoukhteh S
Year: 2020
Journal: Sci Rep
Title: Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics.
Volume: 10
Issue: 1
Pages: 20662
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Publication
32554750 | J:296297
First Author: Zhao Y
Year: 2020
Journal: Cancer Res
Title: Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Volume: 80
Issue: 16
Pages: 3359-3371
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Publication
25060520 | J:215991
First Author: Ostapoff KT
Year: 2014
Journal: Cancer Res
Title: Neutralizing murine TGFβR2 promotes a differentiated tumor cell phenotype and inhibits pancreatic cancer metastasis.
Volume: 74
Issue: 18
Pages: 4996-5007
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Publication
30333153 | J:271159
First Author: Zhang Y
Year: 2019
Journal: Mol Cancer Res
Title: Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer.
Volume: 17
Issue: 2
Pages: 348-355
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Publication
29180468 | J:253868
First Author: Ludwig KF
Year: 2018
Journal: Cancer Res
Title: Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.
Volume: 78
Issue: 1
Pages: 246-255
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Publication
26577699 | J:226828
First Author: Wang M
Year: 2015
Journal: Cancer Res
Title: Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer.
Volume: 75
Issue: 23
Pages: 5058-69
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32156729 | J:286585
First Author: Wasylishen AR
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress.
Volume: 117
Issue: 12
Pages: 6622-6629
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Publication
23980075 | J:316965
First Author: Lashinger LM
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.
Volume: 6
Issue: 10
Pages: 1046-55
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Publication
33811159 | J:317158
First Author: Du W
Year: 2021
Journal: Mol Cancer Res
Title: AXL Is a Key Factor for Cell Plasticity and Promotes Metastasis in Pancreatic Cancer.
Volume: 19
Issue: 8
Pages: 1412-1421
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Publication
26943320 | J:259266
First Author: Thakur AK
Year: 2016
Journal: Cell Death Differ
Title: TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma.
Volume: 23
Issue: 8
Pages: 1358-70
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Publication
28685754 | J:249571
 
First Author: Olivares O
Year: 2017
Journal: Nat Commun
Title: Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Volume: 8
Pages: 16031
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Publication
35166234 | J:351458
 
First Author: Fang Y
Year: 2022
Journal: J Clin Invest
Title: Age-related GSK3β overexpression drives podocyte senescence and glomerular aging.
Volume: 132
Issue: 4
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Publication
25808866 | J:221117
First Author: Klingler S
Year: 2015
Journal: Cancer Res
Title: Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.
Volume: 75
Issue: 10
Pages: 2109-19
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Publication
31138602 | J:279045
First Author: Kircher DA
Year: 2019
Journal: Mol Cancer Res
Title: AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.
Volume: 17
Issue: 9
Pages: 1787-1800
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Publication
30787016 | J:274226
First Author: Fischer GM
Year: 2019
Journal: Cancer Discov
Title: Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
Volume: 9
Issue: 5
Pages: 628-645
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Publication
39098861 | J:352960
First Author: Wee Y
Year: 2024
Journal: Nat Commun
Title: Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy.
Volume: 15
Issue: 1
Pages: 6613
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Publication
34469740 | J:314211
First Author: Maity P
Year: 2021
Journal: Cell Rep
Title: Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging.
Volume: 36
Issue: 9
Pages: 109634
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Publication
21911473 | J:178645
First Author: Vaites LP
Year: 2011
Journal: Mol Cell Biol
Title: The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.
Volume: 31
Issue: 22
Pages: 4513-23
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22552287 | J:189320
First Author: Ramkumar C
Year: 2012
Journal: Cancer Res
Title: Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.
Volume: 72
Issue: 11
Pages: 2714-9
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Publication
27236105 | J:235072
First Author: Halaban R
Year: 2016
Journal: J Invest Dermatol
Title: RASopathy Gene Mutations in Melanoma.
Volume: 136
Issue: 9
Pages: 1755-9
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Publication
23949224 | J:309807
 
First Author: Jackstadt R
Year: 2013
Journal: Cell Death Dis
Title: AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation.
Volume: 4
Pages: e775
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Publication
15485902 | J:94174
First Author: Brady SN
Year: 2004
Journal: Mol Cell Biol
Title: ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway.
Volume: 24
Issue: 21
Pages: 9327-38
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Publication
24616519 | J:207374
First Author: Mitrea DM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Structural polymorphism in the N-terminal oligomerization domain of NPM1.
Volume: 111
Issue: 12
Pages: 4466-71
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Publication
11748239 | J:74741
First Author: Brummelkamp TR
Year: 2002
Journal: J Biol Chem
Title: TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.
Volume: 277
Issue: 8
Pages: 6567-72
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Publication
9244355 | J:41862
First Author: Zindy F
Year: 1997
Journal: Oncogene
Title: Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.
Volume: 15
Issue: 2
Pages: 203-11
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Publication
10341712 | J:51883
First Author: Prives C
Year: 1999
Journal: J Pathol
Title: The p53 pathway.
Volume: 187
Issue: 1
Pages: 112-26
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Publication
10498883 | J:58237
First Author: Roussel MF
Year: 1999
Journal: Oncogene
Title: The INK4 family of cell cycle inhibitors in cancer.
Volume: 18
Issue: 38
Pages: 5311-7
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Publication
12578823 | J:82960
First Author: Guo F
Year: 2003
Journal: J Biol Chem
Title: p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities.
Volume: 278
Issue: 16
Pages: 14414-9
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Publication
17277230 | J:122118
First Author: Li J
Year: 2007
Journal: Carcinogenesis
Title: Nucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability.
Volume: 28
Issue: 6
Pages: 1163-70
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Publication
17704327 | J:124158
 
First Author: Jawad M
Year: 2007
Journal: Br J Radiol
Title: Target cell frequency is a genetically determined risk factor in radiation leukaemogenesis.
Volume: 80 Spec No 1
Pages: S56-62
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Publication
19202064 | J:146457
First Author: Tzatsos A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus.
Volume: 106
Issue: 8
Pages: 2641-6
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Publication
22378045 | J:184561
First Author: Zerrouqi A
Year: 2012
Journal: J Clin Invest
Title: P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.
Volume: 122
Issue: 4
Pages: 1283-95
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Publication
22751500 | J:185344
First Author: Chen AJ
Year: 2012
Journal: Genes Dev
Title: STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.
Volume: 26
Issue: 13
Pages: 1459-72
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Publication
26418719 | J:316142
First Author: Peyre M
Year: 2015
Journal: Oncotarget
Title: PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss.
Volume: 6
Issue: 32
Pages: 32713-22
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Publication
23401854 | J:203321
First Author: Zhang Y
Year: 2013
Journal: Mol Cell Biol
Title: P19ARF and RasV¹² offer opposing regulation of DHX33 translation to dictate tumor cell fate.
Volume: 33
Issue: 8
Pages: 1594-607
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Publication
24632607 | J:218621
First Author: Camacho CV
Year: 2015
Journal: Oncogene
Title: DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.
Volume: 34
Issue: 8
Pages: 1064-72
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Publication
25712345 | J:220158
First Author: Scortegagna M
Year: 2015
Journal: Cancer Res
Title: PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
Volume: 75
Issue: 7
Pages: 1399-412
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Publication
25990896 | J:224786
First Author: Carrasco-Garcia E
Year: 2015
Journal: Aging Cell
Title: Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline.
Volume: 14
Issue: 4
Pages: 710-4
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Publication
28985506 | J:251938
First Author: Chen D
Year: 2017
Journal: Mol Cell
Title: NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.
Volume: 68
Issue: 1
Pages: 224-232.e4
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Publication
27664376 | J:317254
First Author: Azzopardi S
Year: 2016
Journal: Neoplasia
Title: p53 and p16Ink4a/p19Arf Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells.
Volume: 18
Issue: 10
Pages: 610-617
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Publication
15361884 | J:93211
First Author: Qi Y
Year: 2004
Journal: Nature
Title: p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Volume: 431
Issue: 7009
Pages: 712-7
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22561347 | J:185559
First Author: Chio II
Year: 2012
Journal: Nat Cell Biol
Title: TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation.
Volume: 14
Issue: 6
Pages: 625-33
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28463229 | J:244758
First Author: Olvedy M
Year: 2017
Journal: J Clin Invest
Title: Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.
Volume: 127
Issue: 6
Pages: 2310-2325
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19524511 | J:157347
First Author: Inomata K
Year: 2009
Journal: Cell
Title: Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.
Volume: 137
Issue: 6
Pages: 1088-99
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21512139 | J:172206
First Author: Young NP
Year: 2011
Journal: Cancer Res
Title: Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis.
Volume: 71
Issue: 11
Pages: 4040-7
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17392427 | J:120371
First Author: Stecca B
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Volume: 104
Issue: 14
Pages: 5895-900
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Publication
28746871 | J:254287
First Author: Zingg D
Year: 2017
Journal: Cell Rep
Title: The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.
Volume: 20
Issue: 4
Pages: 854-867
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Publication
21075310 | J:166831
First Author: Lee KE
Year: 2010
Journal: Cancer Cell
Title: Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
Volume: 18
Issue: 5
Pages: 448-58
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36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
31896747 | J:284826
First Author: He D
Year: 2020
Journal: Nat Commun
Title: Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway.
Volume: 11
Issue: 1
Pages: 37
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34284046 | J:314692
     
First Author: Zhu X
Year: 2021
Journal: J Invest Dermatol
Title: HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre‒Basal Cell Carcinoma through p16 and p53.
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25157181 | J:218704
First Author: Rodríguez-Díez E
Year: 2014
Journal: Blood
Title: Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis.
Volume: 124
Issue: 15
Pages: 2380-90
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22729085 | J:190763
First Author: Kua HY
Year: 2012
Journal: Nat Cell Biol
Title: c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression.
Volume: 14
Issue: 7
Pages: 727-37
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Publication
16397221 | J:105031
First Author: Hruban RH
Year: 2006
Journal: Cancer Res
Title: Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Volume: 66
Issue: 1
Pages: 95-106
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25605372 | J:221399
First Author: Sheikh BN
Year: 2015
Journal: Blood
Title: MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.
Volume: 125
Issue: 12
Pages: 1910-21
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22907756 | J:189250
First Author: Widau RC
Year: 2012
Journal: Mol Cell Biol
Title: p19Arf represses platelet-derived growth factor receptor β by transcriptional and posttranscriptional mechanisms.
Volume: 32
Issue: 21
Pages: 4270-82
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15665276 | J:95440
First Author: Pantoja C
Year: 2005
Journal: Cancer Res
Title: Inactivation of imprinted genes induced by cellular stress and tumorigenesis.
Volume: 65
Issue: 1
Pages: 26-33
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15870287 | J:99136
First Author: Bardeesy N
Year: 2005
Journal: Mol Cell Biol
Title: Role of epidermal growth factor receptor signaling in RAS-driven melanoma.
Volume: 25
Issue: 10
Pages: 4176-88
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19321450 | J:150510
First Author: Kim J
Year: 2009
Journal: J Biol Chem
Title: Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes.
Volume: 284
Issue: 21
Pages: 14396-404
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23933255 | J:201893
First Author: Putz EM
Year: 2013
Journal: Cell Rep
Title: CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
Volume: 4
Issue: 3
Pages: 437-44
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29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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23754744 | J:204567
First Author: Shamma A
Year: 2013
Journal: Mol Cell Biol
Title: ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.
Volume: 33
Issue: 16
Pages: 3113-24
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17676052 | J:125101
First Author: Kirsch DG
Year: 2007
Journal: Nat Med
Title: A spatially and temporally restricted mouse model of soft tissue sarcoma.
Volume: 13
Issue: 8
Pages: 992-7
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17632527 | J:126550
First Author: Dierks C
Year: 2007
Journal: Nat Med
Title: Essential role of stromally induced hedgehog signaling in B-cell malignancies.
Volume: 13
Issue: 8
Pages: 944-51
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17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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25252692 | J:220627
First Author: Burd CE
Year: 2014
Journal: Cancer Discov
Title: Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Volume: 4
Issue: 12
Pages: 1418-29
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22611036 | J:187012
First Author: Singh M
Year: 2012
Journal: J Pathol
Title: Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Volume: 227
Issue: 4
Pages: 417-30
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17676035 | J:124682
First Author: Ji H
Year: 2007
Journal: Nature
Title: LKB1 modulates lung cancer differentiation and metastasis.
Volume: 448
Issue: 7155
Pages: 807-10
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23266956 | J:195229
First Author: Lo B
Year: 2012
Journal: J Cell Biol
Title: Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.
Volume: 199
Issue: 7
Pages: 1117-30
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15894267 | J:98936
First Author: Hingorani SR
Year: 2005
Journal: Cancer Cell
Title: Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Volume: 7
Issue: 5
Pages: 469-83
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23453624 | J:197054
First Author: Eser S
Year: 2013
Journal: Cancer Cell
Title: Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Volume: 23
Issue: 3
Pages: 406-20
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Publication
27135738 | J:239472
First Author: Souroullas GP
Year: 2016
Journal: Nat Med
Title: An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Volume: 22
Issue: 6
Pages: 632-40
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23845441 | J:199307
First Author: Rad R
Year: 2013
Journal: Cancer Cell
Title: A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.
Volume: 24
Issue: 1
Pages: 15-29
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17299132 | J:121715
First Author: Dankort D
Year: 2007
Journal: Genes Dev
Title: A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors.
Volume: 21
Issue: 4
Pages: 379-84
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15210712 | J:92528
First Author: Carstens MJ
Year: 2004
Journal: J Biol Chem
Title: Cell cycle arrest and cell death are controlled by p53-dependent and p53-independent mechanisms in Tsg101-deficient cells.
Volume: 279
Issue: 34
Pages: 35984-94
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