Type |
Details |
Score |
Publication |
First Author: |
Klarlund JK |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1. |
Volume: |
276 |
Issue: |
43 |
Pages: |
40065-70 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nsdhl/Nsdhl<+> |
Background: |
involves: 101/H * C3H/HeH |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Edar/Edar |
Background: |
involves: FVB/N |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
Vasodilator-stimulated phosphoprotein (VASP) is an actin cytoskeletal regulatory protein. This superfamily corresponds to the tetramerisation domain which forms a right handed alpha helical coiled coil structure []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Vasodilator-stimulated phosphoprotein (VASP) is an actin cytoskeletal regulatory protein. This region corresponds to the tetramerisation domain which forms a right handed alpha helical coiled coil structure []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This is a family of unknown function mainly found in bacteria and archaea. A number of this family members have a coiled coil domain at their C terminus. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4481
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4731
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4621
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4644
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4250
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4456
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4083
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4596
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4144
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4024
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4072
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4462
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4459
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4489
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4488
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4456
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4092
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4591
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4068
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4534
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4024
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4024
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4488
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4481
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4453
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4484
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Smits P |
Year: |
2001 |
Journal: |
Dev Cell |
Title: |
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. |
Volume: |
1 |
Issue: |
2 |
Pages: |
277-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smits P |
Year: |
2004 |
Journal: |
J Cell Biol |
Title: |
Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. |
Volume: |
164 |
Issue: |
5 |
Pages: |
747-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee Y |
Year: |
2005 |
Journal: |
Mol Cell Neurosci |
Title: |
Ocular abnormalities in Large(myd) and Large(vls) mice, spontaneous models for muscle, eye, and brain diseases. |
Volume: |
30 |
Issue: |
2 |
Pages: |
160-72 |
|
•
•
•
•
•
|
Allele |
Name: |
kinesin family member 3C; targeted mutation 1, Lawrence S B Goldstein |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Smits P |
Year: |
2003 |
Journal: |
Development |
Title: |
Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs. |
Volume: |
130 |
Issue: |
6 |
Pages: |
1135-48 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Shinichi Uchida |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sox5/Sox5<+> Sox6/Sox6<+> |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sox5/Sox5 Sox6/Sox6 |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Myh10/Myh10 |
Background: |
involves: 129S4/SvJae * 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sox5/Sox5 Sox6/Sox6<+> |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4306
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
39
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
This superfamily represents the N-terminal coiled coil domain of the delta antigen from the hepatitis D virus (HDV). The hepatitis delta antigen dimerises through this anti-parallel coiled coil domain. Dimers then associate further to form octamers through residues in the coiled-coil domain and residues C-terminal to this domain. This domain may play a role in binding the viral RNA []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Schenker T |
Year: |
2000 |
Journal: |
Biochim Biophys Acta |
Title: |
BSPRY, a novel protein of the Ro-Ret family. |
Volume: |
1493 |
Issue: |
1-2 |
Pages: |
255-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsubara M |
Year: |
1998 |
Journal: |
FEBS Lett |
Title: |
MARCKS, a major protein kinase C substrate, assumes non-helical conformations both in solution and in complex with Ca2+-calmodulin. |
Volume: |
421 |
Issue: |
3 |
Pages: |
203-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dames SA |
Year: |
1998 |
Journal: |
Nat Struct Biol |
Title: |
NMR structure of a parallel homotrimeric coiled coil. |
Volume: |
5 |
Issue: |
8 |
Pages: |
687-91 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaur G |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Evolutionary convergence and divergence in archaeal chromosomal proteins and Chromo-like domains from bacteria and eukaryotes. |
Volume: |
8 |
Issue: |
1 |
Pages: |
6196 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Cytochrome c oxidase assembly factor 3, previously known as coiled coil domain-containing protein 56 (CCDC56), plays a critical role in the biogenesis and activity of cytochrome c oxidase (COX) []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This is the coiled coil (CC) - marked box (MB) domain of E2F transcription factors. This domain forms a heterodimer with the corresponding domain of the DP transcription factor, the heterodimer binds the C terminus of retinoblastoma protein []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Several proteins have been identified that localise to centrosomes and spindle poles, and they have been named accordingly to their molecular weight []. This entry represents a coiled coil domain found in centrosomal protein of 44kDa (CEP44). |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain occurs at the N terminus of Rnk (regulator of nucleoside diphosphate kinase), an RNA polymerase-interacting protein of the GreA/GreB family []. It has a coiled coil structure []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This family represents the small subunit of the Fe-only hydrogenases (). The subunit is comprised of alternating random coil and α-helical structures that encompasses the large subunit in a novel protein fold []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The B-box C-terminal domain is a coiled coil region C-terminal to (some) B-Box domains. It is found in transcription intermediary factor 1-alpha, which associates with DNA-bound estrogen receptors; ring finger protein, a putative transcriptional regulator; and the GTP-binding protein Ard-1. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The structure of a representative of this family has been solved and found to form a tetrameric structure of prefoldin-like architecture with the β-barrel core and helical coiled coil tentacles. This suggests that this family may act as molecular chaperones. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Tetrabrachion forms a parallel right-handed coiled coil structure with hydrophobic interactions and salt bridges forming a thermostable tetrameric structure. It contains large hydrophobic cavities. No function is known for this family of proteins []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
108
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Carlberg I |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A novel plant protein undergoing light-induced phosphorylation and release from the photosynthetic thylakoid membranes. |
Volume: |
100 |
Issue: |
2 |
Pages: |
757-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin PB |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease. |
Volume: |
11 |
Issue: |
1 |
Pages: |
4625 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brent AE |
Year: |
2005 |
Journal: |
Development |
Title: |
Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development. |
Volume: |
132 |
Issue: |
3 |
Pages: |
515-28 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamauchi K |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice. |
Volume: |
332 |
Issue: |
3 |
Pages: |
750-5 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kif3c/Kif3c |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sox5/Sox5 Sox6/Sox6 Tg(Col2a1-cre)1Bhr/? |
Background: |
involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
ectodysplasin-A receptor; downless Jackson |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Allele |
Name: |
wingless-type MMTV integration site family, member 10A; targeted mutation 1, Sarah E Millar |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
wingless-type MMTV integration site family, member 10A; targeted mutation 1.1, Sarah E Millar |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(KRT5-rtTA)#Glk/? Tg(tetO-cre)1Jaw/? Wnt10a/Wnt10a |
Background: |
involves: 129X1/SvJ * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kambouris M |
Year: |
1994 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. |
Volume: |
25 |
Issue: |
3-4 |
Pages: |
183-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siletti K |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. |
Volume: |
114 |
Issue: |
52 |
Pages: |
E11170-E11179 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ding W |
Year: |
2021 |
Journal: |
Sci China Life Sci |
Title: |
Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice. |
Volume: |
64 |
Issue: |
3 |
Pages: |
419-433 |
|
•
•
•
•
•
|
Publication |
First Author: |
Otto T |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. |
Volume: |
114 |
Issue: |
40 |
Pages: |
10660-10665 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi T |
Year: |
2014 |
Journal: |
J Cell Biol |
Title: |
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. |
Volume: |
204 |
Issue: |
2 |
Pages: |
215-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brahmaraju M |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Spatio-temporal organization of Vam6P and SNAP on mouse spermatozoa and their involvement in sperm-zona pellucida interactions. |
Volume: |
318 |
Issue: |
1 |
Pages: |
148-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor MS |
Year: |
2003 |
Journal: |
Genomics |
Title: |
Evolutionary constraints on the Disrupted in Schizophrenia locus. |
Volume: |
81 |
Issue: |
1 |
Pages: |
67-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andreu N |
Year: |
2001 |
Journal: |
Gene |
Title: |
PALML, a novel paralemmin-related gene mapping on human chromosome 1p21. |
Volume: |
278 |
Issue: |
1-2 |
Pages: |
33-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao B |
Year: |
1998 |
Journal: |
Neuron |
Title: |
Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. |
Volume: |
21 |
Issue: |
4 |
Pages: |
707-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shimada K |
Year: |
2019 |
Journal: |
J Reprod Dev |
Title: |
Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yang F |
Year: |
2006 |
Journal: |
J Cell Biol |
Title: |
Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. |
Volume: |
173 |
Issue: |
4 |
Pages: |
497-507 |
|
•
•
•
•
•
|
Publication |
First Author: |
Orimo A |
Year: |
2000 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC. |
Volume: |
276 |
Issue: |
1 |
Pages: |
45-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borinstein SC |
Year: |
2000 |
Journal: |
Cell Signal |
Title: |
SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. |
Volume: |
12 |
Issue: |
11-12 |
Pages: |
769-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Z |
Year: |
2008 |
Journal: |
Biol Reprod |
Title: |
Phosphorylation of mouse sperm axoneme central apparatus protein SPAG16L by a testis-specific kinase, TSSK2. |
Volume: |
79 |
Issue: |
1 |
Pages: |
75-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gatfield J |
Year: |
2005 |
Journal: |
Mol Biol Cell |
Title: |
Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules. |
Volume: |
16 |
Issue: |
6 |
Pages: |
2786-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weidner P |
Year: |
2024 |
Journal: |
Cancer Lett |
Title: |
Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction. |
Volume: |
588 |
|
Pages: |
216783 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tu X |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Interruption of post-Golgi STING trafficking activates tonic interferon signaling. |
Volume: |
13 |
Issue: |
1 |
Pages: |
6977 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shim JH |
Year: |
2006 |
Journal: |
J Cell Biol |
Title: |
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. |
Volume: |
172 |
Issue: |
7 |
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