| Type |
Details |
Score |
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1754428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360991 |
|
| Specimen Label: |
BCM_1360991 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3278228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360990 |
|
| Specimen Label: |
BCM_1360990 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360987 |
|
| Specimen Label: |
BCM_1360987 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360988 |
|
| Specimen Label: |
BCM_1360988 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360989 |
|
| Specimen Label: |
BCM_1360989 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360991 |
|
| Specimen Label: |
BCM_1360991 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1610528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972600 |
|
| Specimen Label: |
BCM_1972600 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1610528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972601 |
|
| Specimen Label: |
BCM_1972601 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1860128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972600 |
|
| Specimen Label: |
BCM_1972600 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1860128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972601 |
|
| Specimen Label: |
BCM_1972601 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3283428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972609 |
|
| Specimen Label: |
BCM_1972609 |
| Detected: |
true |
| Specimen Num: |
29 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:1842628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360981 |
|
| Specimen Label: |
BCM_1360981 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3556128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360982 |
|
| Specimen Label: |
BCM_1360982 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1920928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972603 |
|
| Specimen Label: |
BCM_1972603 |
| Detected: |
true |
| Specimen Num: |
23 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1685328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972595 |
|
| Specimen Label: |
BCM_1972595 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1684628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972596 |
|
| Specimen Label: |
BCM_1972596 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1684628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972597 |
|
| Specimen Label: |
BCM_1972597 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1750328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972599 |
|
| Specimen Label: |
BCM_1972599 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1541405 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824201 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_007077_06 |
|
| Specimen Label: |
euxassay_007077_06 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1541405 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824201 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_007077_07 |
|
| Specimen Label: |
euxassay_007077_07 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1541405 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824201 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_007077_15 |
|
| Specimen Label: |
euxassay_007077_15 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1541405 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824201 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_007077_16 |
|
| Specimen Label: |
euxassay_007077_16 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1541405 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1842723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824201 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_007077_17 |
|
| Specimen Label: |
euxassay_007077_17 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972606 |
|
| Specimen Label: |
BCM_1972606 |
| Detected: |
true |
| Specimen Num: |
26 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1928728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972607 |
|
| Specimen Label: |
BCM_1972607 |
| Detected: |
true |
| Specimen Num: |
27 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1876828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972602 |
|
| Specimen Label: |
BCM_1972602 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1683328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360986 |
|
| Specimen Label: |
BCM_1360986 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3271628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360990 |
|
| Specimen Label: |
BCM_1360990 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3599828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972608 |
|
| Specimen Label: |
BCM_1972608 |
| Detected: |
true |
| Specimen Num: |
28 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3590528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360990 |
|
| Specimen Label: |
BCM_1360990 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3590528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972600 |
|
| Specimen Label: |
BCM_1972600 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3590528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972601 |
|
| Specimen Label: |
BCM_1972601 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972598 |
|
| Specimen Label: |
BCM_1972598 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360986 |
|
| Specimen Label: |
BCM_1360986 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3592628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972605 |
|
| Specimen Label: |
BCM_1972605 |
| Detected: |
true |
| Specimen Num: |
25 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3273028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360990 |
|
| Specimen Label: |
BCM_1360990 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360993 |
|
| Specimen Label: |
BCM_1360993 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3281228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1972595 |
|
| Specimen Label: |
BCM_1972595 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2991528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360983 |
|
| Specimen Label: |
BCM_1360983 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360987 |
|
| Specimen Label: |
BCM_1360987 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360988 |
|
| Specimen Label: |
BCM_1360988 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360989 |
|
| Specimen Label: |
BCM_1360989 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360991 |
|
| Specimen Label: |
BCM_1360991 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691096 |
| Age: |
postnatal adult |
| Image: |
BCM_1360983 |
|
| Specimen Label: |
BCM_1360983 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
525
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
335
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
524
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kosaka Y |
| Year: |
2006 |
| Journal: |
Trends Immunol |
| Title: |
Itk and Th2 responses: action but no reaction. |
| Volume: |
27 |
| Issue: |
10 |
| Pages: |
453-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bogin Y |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK. |
| Volume: |
104 |
| Issue: |
16 |
| Pages: |
6638-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang YH |
| Year: |
2007 |
| Journal: |
Science |
| Title: |
Positive regulation of Itk PH domain function by soluble IP4. |
| Volume: |
316 |
| Issue: |
5826 |
| Pages: |
886-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
King PD |
| Year: |
1998 |
| Journal: |
Int Immunol |
| Title: |
CD2-mediated activation of the Tec-family tyrosine kinase ITK is controlled by proline-rich stretch-4 of the CD2 cytoplasmic tail. |
| Volume: |
10 |
| Issue: |
7 |
| Pages: |
1009-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jain N |
| Year: |
2013 |
| Journal: |
Nat Med |
| Title: |
CD28 and ITK signals regulate autoreactive T cell trafficking. |
| Volume: |
19 |
| Issue: |
12 |
| Pages: |
1632-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berg LJ |
| Year: |
2007 |
| Journal: |
Nat Rev Immunol |
| Title: |
Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. |
| Volume: |
7 |
| Issue: |
6 |
| Pages: |
479-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prince AL |
| Year: |
2009 |
| Journal: |
Immunol Rev |
| Title: |
The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. |
| Volume: |
228 |
| Issue: |
1 |
| Pages: |
115-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brown K |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. |
| Volume: |
279 |
| Issue: |
18 |
| Pages: |
18727-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qi Q |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Tec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors. |
| Volume: |
281 |
| Issue: |
50 |
| Pages: |
38529-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsoukas CD |
| Year: |
2006 |
| Journal: |
Adv Exp Med Biol |
| Title: |
Inducible T cell tyrosine kinase (ITK): structural requirements and actin polymerization. |
| Volume: |
584 |
|
| Pages: |
29-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kutach AK |
| Year: |
2010 |
| Journal: |
Chem Biol Drug Des |
| Title: |
Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation. |
| Volume: |
76 |
| Issue: |
2 |
| Pages: |
154-63 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
PTKs catalyse the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. Itk, also known as Tsk or Emt, is a member of the Tec-like subfamily of proteins, which are cytoplasmic (or nonreceptor) PTKs with similarity to Src kinases in that they contain Src homology protein interaction domains (SH3, SH2) N-terminal to the catalytic tyr kinase domain. Unlike Src kinases, most Tec subfamily members except Rlk also contain an N-terminal pleckstrin homology (PH) domain, which binds the products of PI3K and allows membrane recruitment and activation. In addition, Itk contains the Tec homology (TH) domain containing one proline-rich region and a zinc-binding region [, ].Itk is expressed in T-cells and mast cells, and is important in their development and differentiation []. Of the three Tec kinases expressed in T-cells, Itk plays the predominant role in T-cell receptor (TCR) signalling. It is activated by phosphorylation upon TCR crosslinking and is involved in the pathway resulting in phospholipase C-gamma1 activation and actin polymerization []. It also plays a role in the downstream signalling of the T-cell costimulatory receptor CD28, the T-cell surface receptor CD2, and the chemokine receptor CXCR4 [, ]. In addition, Itk is crucial for the development of T-helper(Th)2 effector responses []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
ITK (also known as Tsk or Emt) is a member of the Tec family, which is a group of nonreceptor tyrosine kinases containing Src homology protein interaction domains (SH3, SH2) N-terminal to the catalytic tyr kinase domain. It also contains an N-terminal pleckstrin homology (PH) domain, which binds the products of PI3K and allows membrane recruitment and activation [], and the Tec homology (TH) domain, which contains proline-rich and zinc-binding regions. ITK is expressed in T-cells and mast cells, and is important in their development and differentiation [, ]. Of the three Tec kinases expressed in T-cells, ITK plays the predominant role in T-cell receptor (TCR) signaling. It is activated by phosphorylation upon TCR crosslinking and is involved in the pathway resulting in phospholipase C-gamma1 activation and actin polymerization []. It also plays a role in the downstream signaling of the T-cell costimulatory receptor CD28 [], the T-cell surface receptor CD2 [], and the chemokine receptor CXCR4 []. In addition, ITK is crucial for the development of T-helper(Th)2 effector responses []. This entry represents the SH3 domain of ITK. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
359
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
359
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tomasetto C |
| Year: |
1990 |
| Journal: |
EMBO J |
| Title: |
hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
407-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quante M |
| Year: |
2010 |
| Journal: |
Gastroenterology |
| Title: |
TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa. |
| Volume: |
139 |
| Issue: |
6 |
| Pages: |
2018-2027.e2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farrell JJ |
| Year: |
2002 |
| Journal: |
J Clin Invest |
| Title: |
TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. |
| Volume: |
109 |
| Issue: |
2 |
| Pages: |
193-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fox JG |
| Year: |
2007 |
| Journal: |
Am J Pathol |
| Title: |
Accelerated progression of gastritis to dysplasia in the pyloric antrum of TFF2 -/- C57BL6 x Sv129 Helicobacter pylori-infected mice. |
| Volume: |
171 |
| Issue: |
5 |
| Pages: |
1520-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nikolaidis NM |
| Year: |
2006 |
| Journal: |
Exp Lung Res |
| Title: |
Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung. |
| Volume: |
32 |
| Issue: |
10 |
| Pages: |
483-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurt-Jones EA |
| Year: |
2007 |
| Journal: |
Infect Immun |
| Title: |
Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. |
| Volume: |
75 |
| Issue: |
1 |
| Pages: |
471-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McBerry C |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii. |
| Volume: |
189 |
| Issue: |
6 |
| Pages: |
3078-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baus-Loncar M |
| Year: |
2005 |
| Journal: |
Cell Physiol Biochem |
| Title: |
Trefoil factor 2 (TFF2) deficiency in murine digestive tract influences the immune system. |
| Volume: |
16 |
| Issue: |
1-3 |
| Pages: |
31-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nomura S |
| Year: |
2004 |
| Journal: |
Gastroenterology |
| Title: |
Spasmolytic polypeptide expressing metaplasia to preneoplasia in H. felis-infected mice. |
| Volume: |
127 |
| Issue: |
2 |
| Pages: |
582-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hung LY |
| Year: |
2018 |
| Journal: |
Am J Pathol |
| Title: |
Trefoil Factor 2 Promotes Type 2 Immunity and Lung Repair through Intrinsic Roles in Hematopoietic and Nonhematopoietic Cells. |
| Volume: |
188 |
| Issue: |
5 |
| Pages: |
1161-1170 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Brain |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Kidney |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Thymus |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Liver |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702128 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Stomach |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3557728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Muscle |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Lung |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2665965 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2666125 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Testis |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|