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Search results 1201 to 1300 out of 1316 for Fyn

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Type Details Score
Publication
38254202 | J:358300
First Author: Zhang Y
Year: 2024
Journal: Cell Commun Signal
Title: Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation.
Volume: 22
Issue: 1
Pages: 58
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Publication
22885232 | J:192490
 
First Author: Olausson P
Year: 2012
Journal: Neuroscience
Title: The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity.
Volume: 225
Pages: 1-8
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Publication
25103464 | J:225622
First Author: Sukoff Rizzo SJ
Year: 2014
Journal: Genes Brain Behav
Title: Behavioral characterization of striatal-enriched protein tyrosine phosphatase (STEP) knockout mice.
Volume: 13
Issue: 7
Pages: 643-52
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Publication
29678909 | J:302645
First Author: Lesiak AJ
Year: 2018
Journal: Mol Pharmacol
Title: Restoration of Physiological Expression of 5-HT6 Receptor into the Primary Cilia of Null Mutant Neurons Lengthens Both Primary Cilia and Dendrites.
Volume: 94
Issue: 1
Pages: 731-742
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Publication
26849944 | J:312252
 
First Author: Cheng Y
Year: 2016
Journal: Free Radic Biol Med
Title: Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy.
Volume: 93
Pages: 94-109
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Publication
19934324 | J:155536
First Author: Zhao L
Year: 2009
Journal: Cancer Res
Title: Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53.
Volume: 69
Issue: 24
Pages: 9439-47
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Publication
25246632 | J:224327
First Author: Draberova L
Year: 2014
Journal: Mol Cell Biol
Title: Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling.
Volume: 34
Issue: 23
Pages: 4285-300
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Publication
29748289 | J:263498
First Author: Samovski D
Year: 2018
Journal: Diabetes
Title: Regulation of Insulin Receptor Pathway and Glucose Metabolism by CD36 Signaling.
Volume: 67
Issue: 7
Pages: 1272-1284
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Publication
33230162 | J:300222
First Author: Yang T
Year: 2020
Journal: Sci Rep
Title: Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies.
Volume: 10
Issue: 1
Pages: 20322
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Publication
36855057 | J:347883
First Author: Chen L
Year: 2023
Journal: Cell Biosci
Title: ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation.
Volume: 13
Issue: 1
Pages: 42
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Publication
28383553 | J:260051
First Author: Yu W
Year: 2017
Journal: Cell Death Dis
Title: Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain.
Volume: 8
Issue: 4
Pages: e2737
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Publication
30341149 | J:292970
First Author: Wei C
Year: 2018
Journal: J Am Soc Nephrol
Title: SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts.
Volume: 29
Issue: 11
Pages: 2641-2657
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Publication
17137665 | J:119931
First Author: Kotani T
Year: 2007
Journal: Neurosci Res
Title: Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells.
Volume: 57
Issue: 2
Pages: 210-9
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Publication
8626447 | J:31951
First Author: Richards JD
Year: 1996
Journal: J Biol Chem
Title: Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.
Volume: 271
Issue: 11
Pages: 6458-66
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Publication
24068671 | J:206245
First Author: Fernando J
Year: 2013
Journal: J Immunol
Title: Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway.
Volume: 191
Issue: 9
Pages: 4505-13
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Publication
23386614 | J:240258
First Author: Rushworth JV
Year: 2013
Journal: J Biol Chem
Title: Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1.
Volume: 288
Issue: 13
Pages: 8935-51
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Publication
8395016 | J:200363
First Author: Pleiman CM
Year: 1993
Journal: Mol Cell Biol
Title: Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase.
Volume: 13
Issue: 9
Pages: 5877-87
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Publication
19816407 | J:200384
First Author: Lim SH
Year: 2009
Journal: EMBO J
Title: Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.
Volume: 28
Issue: 22
Pages: 3564-78
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Publication
10781838 | J:62319
First Author: Ulivieri C
Year: 2000
Journal: Mol Immunol
Title: Restoration of thymic development in an Lck(-/-) thymoma overexpressing ZAP-70.
Volume: 37
Issue: 1-2
Pages: 85-90
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Publication
10917895 | J:63837
First Author: Tamura T
Year: 2000
Journal: Int Immunol
Title: Molecular mechanism of the impairment in activation signal transduction in CD4(+) T cells from old mice.
Volume: 12
Issue: 8
Pages: 1205-15
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Publication
8910336 | J:36499
First Author: Pathan NI
Year: 1996
Journal: J Biol Chem
Title: The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2.
Volume: 271
Issue: 44
Pages: 27517-23
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Publication
9109376 | J:39454
First Author: Takayama Y
Year: 1997
Journal: FEBS Lett
Title: Role of Csk in neural differentiation of the embryonic carcinoma cell line P19.
Volume: 406
Issue: 1-2
Pages: 11-6
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Publication
9628820 | J:48154
First Author: Jackson A
Year: 1998
Journal: Genomics
Title: The human homologue of the Drosophila tailless gene (TLX): characterization and mapping to a region of common deletion in human lymphoid leukemia on chromosome 6q21.
Volume: 50
Issue: 1
Pages: 34-43
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Publication
12695509 | J:84113
First Author: Thornton C
Year: 2003
Journal: J Biol Chem
Title: H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity.
Volume: 278
Issue: 26
Pages: 23823-9
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Publication
12912979 | J:86179
First Author: Mukherjee A
Year: 2003
Journal: J Biol Chem
Title: Lipid-dependent recruitment of neuronal Src to lipid rafts in the brain.
Volume: 278
Issue: 42
Pages: 40806-14
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Publication
15121874 | J:89884
First Author: Xing L
Year: 2004
Journal: Mol Cell Biol
Title: The adapter molecule Sin regulates T-cell-receptor-mediated signal transduction by modulating signaling substrate availability.
Volume: 24
Issue: 10
Pages: 4581-92
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Publication
15546912 | J:94211
First Author: Epting CL
Year: 2004
Journal: J Cell Sci
Title: Stem cell antigen-1 is necessary for cell-cycle withdrawal and myoblast differentiation in C2C12 cells.
Volume: 117
Issue: Pt 25
Pages: 6185-95
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Publication
16543952 | J:108940
First Author: Verma R
Year: 2006
Journal: J Clin Invest
Title: Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.
Volume: 116
Issue: 5
Pages: 1346-59
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Publication
17062576 | J:117707
First Author: Honda T
Year: 2006
Journal: J Biol Chem
Title: Mouse Disabled1 (DAB1) is a nucleocytoplasmic shuttling protein.
Volume: 281
Issue: 50
Pages: 38951-65
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Publication
17194753 | J:118993
First Author: Castaño J
Year: 2007
Journal: Mol Cell Biol
Title: Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA.
Volume: 27
Issue: 5
Pages: 1745-57
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Publication
16339523 | J:122247
First Author: Hernandez-Hansen V
Year: 2005
Journal: J Immunol
Title: Increased expression of genes linked to FcepsilonRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells.
Volume: 175
Issue: 12
Pages: 7880-8
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Publication
17569658 | J:124797
First Author: Rybin VO
Year: 2007
Journal: J Biol Chem
Title: Protein kinase Cepsilon (PKCepsilon) and Src control PKCdelta activation loop phosphorylation in cardiomyocytes.
Volume: 282
Issue: 32
Pages: 23631-8
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Publication
18065418 | J:131575
First Author: Tu CL
Year: 2008
Journal: J Biol Chem
Title: Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes.
Volume: 283
Issue: 6
Pages: 3519-28
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Publication
17986008 | J:135360
First Author: Hoshina N
Year: 2007
Journal: Genes Cells
Title: Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth.
Volume: 12
Issue: 11
Pages: 1245-54
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Publication
18523265 | J:137242
First Author: Cross JL
Year: 2008
Journal: J Immunol
Title: CD45 regulates TLR-induced proinflammatory cytokine and IFN-beta secretion in dendritic cells.
Volume: 180
Issue: 12
Pages: 8020-9
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Publication
18653698 | J:140142
First Author: Péterfy H
Year: 2008
Journal: Int Immunol
Title: C3a-derived peptide binds to the type I FcepsilonR and inhibits proximal-coupling signal processes and cytokine secretion by mast cells.
Volume: 20
Issue: 10
Pages: 1239-45
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Publication
17182584 | J:141925
First Author: Kitaura J
Year: 2007
Journal: J Immunol
Title: Dysregulation of Src family kinases in mast cells from epilepsy-resistant ASK versus epilepsy-prone EL mice.
Volume: 178
Issue: 1
Pages: 455-62
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Publication
10620012 | J:150628
First Author: Hisatsune C
Year: 1999
Journal: Genes Cells
Title: Phosphorylation-dependent interaction of the N-methyl-D-aspartate receptor epsilon 2 subunit with phosphatidylinositol 3-kinase.
Volume: 4
Issue: 11
Pages: 657-66
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Publication
19586919 | J:154885
First Author: Clarkson NG
Year: 2009
Journal: J Biol Chem
Title: Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1.
Volume: 284
Issue: 37
Pages: 24725-34
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Publication
20123980 | J:161720
First Author: Liu W
Year: 2010
Journal: Mol Cell Biol
Title: Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function.
Volume: 30
Issue: 7
Pages: 1783-99
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Publication
20702708 | J:163235
First Author: Kleene R
Year: 2010
Journal: J Neurosci
Title: NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments.
Volume: 30
Issue: 32
Pages: 10784-98
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Publication
20497907 | J:165226
First Author: Uchino S
Year: 2010
Journal: Neuroscience
Title: Inhibition of N-methyl-D-aspartate receptor activity resulted in aberrant neuronal migration caused by delayed morphological development in the mouse neocortex.
Volume: 169
Issue: 2
Pages: 609-18
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Publication
21268181 | J:168551
First Author: McGinnis LK
Year: 2011
Journal: Mol Reprod Dev
Title: Fer tyrosine kinase is required for germinal vesicle breakdown and meiosis-I in mouse oocytes.
Volume: 78
Issue: 1
Pages: 33-47
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Publication
22623673 | J:184977
First Author: Bae ON
Year: 2012
Journal: J Neurosci
Title: Lymphocyte cell kinase activation mediates neuroprotection during ischemic preconditioning.
Volume: 32
Issue: 21
Pages: 7278-86
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Publication
22433866 | J:185628
First Author: Liu X
Year: 2012
Journal: J Biol Chem
Title: Slit2 regulates the dispersal of oligodendrocyte precursor cells via Fyn/RhoA signaling.
Volume: 287
Issue: 21
Pages: 17503-16
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Publication
21985328 | J:192070
First Author: Trepanier CH
Year: 2012
Journal: FEBS J
Title: Regulation of NMDA receptors by the tyrosine kinase Fyn.
Volume: 279
Issue: 1
Pages: 12-9
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Publication
24005290 | J:201747
First Author: Ben Hamida S
Year: 2013
Journal: J Neurosci
Title: Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors.
Volume: 33
Issue: 36
Pages: 14369-78
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Publication
24872417 | J:216018
First Author: Kobayashi H
Year: 2014
Journal: J Biol Chem
Title: Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5.
Volume: 289
Issue: 28
Pages: 19627-36
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Publication
26142315 | J:225827
First Author: Ho N
Year: 2015
Journal: Biol Open
Title: Tubedown regulation of retinal endothelial permeability signaling pathways.
Volume: 4
Issue: 8
Pages: 970-9
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Publication
27940916 | J:239068
First Author: Dustrude ET
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.
Volume: 113
Issue: 52
Pages: E8443-E8452
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Publication
29269414 | J:258439
First Author: Sun S
Year: 2018
Journal: J Biol Chem
Title: Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes.
Volume: 293
Issue: 7
Pages: 2383-2394
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Publication
28736076 | J:256326
 
First Author: Nam ST
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Suppression of IgE-mediated mast cell activation and mouse anaphylaxis via inhibition of Syk activation by 8-formyl-7-hydroxy-4-methylcoumarin, 4μ8C.
Volume: 332
Pages: 25-31
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Publication
29588394 | J:261449
 
First Author: Osborne C
Year: 2018
Journal: J Cell Sci
Title: The phospholipase A2 pathway controls a synaptic cholesterol ester cycle and synapse damage.
Volume: 131
Issue: 8
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Publication
24860422 | J:264219
 
First Author: Xia D
Year: 2014
Journal: Front Mol Neurosci
Title: Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.
Volume: 7
Pages: 40
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Publication
30049666 | J:266960
 
First Author: Zhao JY
Year: 2018
Journal: Neuroscience
Title: Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Volume: 388
Pages: 1-10
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Publication
24604355 | J:315536
First Author: Schmitz M
Year: 2014
Journal: Mol Neurobiol
Title: Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression.
Volume: 50
Issue: 3
Pages: 923-36
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Publication
38483947 | J:361157
First Author: Xie Y
Year: 2024
Journal: Adv Sci (Weinh)
Title: Deficiency of Nuclear Receptor Coactivator 3 Aggravates Diabetic Kidney Disease by Impairing Podocyte Autophagy.
Volume: 11
Issue: 19
Pages: e2308378
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Protein
Q9QUG3
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
A7U7N0
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
C7E3P5
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
A0A075B668
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Protein
Q544A3
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Publication
11524679 | -
First Author: Knaus KJ
Year: 2001
Journal: Nat Struct Biol
Title: Crystal structure of the human prion protein reveals a mechanism for oligomerization.
Volume: 8
Issue: 9
Pages: 770-4
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Publication
12595265 | -
First Author: Lührs T
Year: 2003
Journal: J Mol Biol
Title: NMR structure of the human doppel protein.
Volume: 326
Issue: 5
Pages: 1549-57
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Publication
17785178 | J:126808
First Author: Palop JJ
Year: 2007
Journal: Neuron
Title: Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease.
Volume: 55
Issue: 5
Pages: 697-711
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Publication
21746961 | J:177211
First Author: Lee JH
Year: 2011
Journal: J Immunol
Title: The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.
Volume: 187
Issue: 4
Pages: 1807-15
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Publication
28137917 | J:262010
First Author: Dai X
Year: 2017
Journal: Circ Res
Title: Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia.
Volume: 120
Issue: 5
Pages: e7-e23
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Publication
36455410 | J:351530
 
First Author: Gray J
Year: 2022
Journal: EBioMedicine
Title: Heat shock protein amplification improves cerebellar myelination in the Npc1(nih) mouse model.
Volume: 86
Pages: 104374
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Publication
11509585 | J:71174
First Author: Hasegawa M
Year: 2001
Journal: J Immunol
Title: A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice.
Volume: 167
Issue: 5
Pages: 2469-78
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Publication
27363720 | J:236479
First Author: Choi S
Year: 2016
Journal: Aging Cell
Title: KCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stress.
Volume: 15
Issue: 5
Pages: 801-10
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Publication
36272670 | J:331376
First Author: Li T
Year: 2022
Journal: Free Radic Biol Med
Title: BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Volume: 193
Issue: Pt 1
Pages: 304-318
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Publication
25035294 | J:218487
First Author: Brisslert M
Year: 2014
Journal: Biochim Biophys Acta
Title: S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis.
Volume: 1842
Issue: 11
Pages: 2049-59
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Publication
37620160 | J:353836
First Author: Fekete CD
Year: 2023
Journal: J Neurosci
Title: Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord.
Volume: 43
Issue: 39
Pages: 6592-6608
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Publication
37058540 | J:353343
First Author: Qi H
Year: 2023
Journal: PLoS Pathog
Title: Tim-3 regulates the immunosuppressive function of decidual MDSCs via the Fyn-STAT3-C/EBPβ pathway during Toxoplasma gondii infection.
Volume: 19
Issue: 4
Pages: e1011329
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Publication
11716303 | J:72702
First Author: Mastrangelo P
Year: 2001
Journal: Biochem Cell Biol
Title: Biology of the prion gene complex.
Volume: 79
Issue: 5
Pages: 613-28
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Publication
8159769 | J:17627
First Author: Hatakeyama S
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: The murine c-fgr gene product associated with Ly6C and p70 integral membrane protein is expressed in cells of a monocyte/macrophage lineage.
Volume: 91
Issue: 8
Pages: 3458-62
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Publication
20417561 | J:160621
First Author: Lefebvre DC
Year: 2010
Journal: Mol Immunol
Title: CD44 interacts directly with Lck in a zinc-dependent manner.
Volume: 47
Issue: 10
Pages: 1882-9
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Publication
26306036 | J:315385
First Author: Sommerfeld A
Year: 2015
Journal: J Biol Chem
Title: Regulation of plasma membrane localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by hyperosmolarity and tauroursodeoxycholate.
Volume: 290
Issue: 40
Pages: 24237-54
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Publication
23866919 | J:316290
 
First Author: Maier W
Year: 2013
Journal: Mol Neurodegener
Title: LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.
Volume: 8
Pages: 25
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Publication
17062627 | J:137511
First Author: Lin Q
Year: 2006
Journal: Nucleic Acids Res
Title: Mutagenesis of diploid mammalian genes by gene entrapment.
Volume: 34
Issue: 20
Pages: e139
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Publication
10985773 | -
First Author: Misra S
Year: 2000
Journal: Biochemistry
Title: Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes.
Volume: 39
Issue: 37
Pages: 11282-90
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Protein
Q80YF9
Organism: Mus musculus/domesticus
Length: 1305  
Fragment?: false
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Protein
Q923U0
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
O88746
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Protein
Q5SRX1
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
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Protein
Q7TNI6
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
Q8BZR6
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
Q3UQS4
Organism: Mus musculus/domesticus
Length: 1324  
Fragment?: true
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Protein
Q3UDC3
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
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Protein
A0A140LHW2
Organism: Mus musculus/domesticus
Length: 1281  
Fragment?: false
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Protein
Q5SXA4
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q5SXA5
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
•
•
•
•
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Protein
A0A2X0SFM8
Organism: Mus musculus/domesticus
Length: 1307  
Fragment?: true
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•
•
•
•
Protein
Q561M4
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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•
•
•
•
Protein
D3YZ57
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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•
•
•
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Publication
18034455 | -
First Author: Ballif BA
Year: 2008
Journal: J Proteome Res
Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.
Volume: 7
Issue: 1
Pages: 311-8
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•
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Protein
P25911
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
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•
•
•
•
Protein
Q8CEI0
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
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•
•
•
•
Protein
Q3U6Q5
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
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•
•
•
•
Protein
Q3TCS3
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
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•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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