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Search results 1201 to 1300 out of 1398 for H2ax

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Type Details Score
Publication
15178448 | J:90458
First Author: Watanabe F
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Poly(ADP-ribose) polymerase-1 inhibits ATM kinase activity in DNA damage response.
Volume: 319
Issue: 2
Pages: 596-602
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Publication
22802351 | J:186986
First Author: Hiller B
Year: 2012
Journal: J Exp Med
Title: Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity.
Volume: 209
Issue: 8
Pages: 1419-26
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Publication
19112184 | J:148623
First Author: Urtishak KA
Year: 2009
Journal: J Biol Chem
Title: Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.
Volume: 284
Issue: 13
Pages: 8777-85
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Publication
21616937 | J:174072
First Author: Sashida G
Year: 2011
Journal: Cancer Res
Title: The mef/elf4 transcription factor fine tunes the DNA damage response.
Volume: 71
Issue: 14
Pages: 4857-65
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Publication
26764091 | J:314896
First Author: Ma XS
Year: 2016
Journal: Mol Biol Cell
Title: Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility.
Volume: 27
Issue: 5
Pages: 768-75
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Publication
30952868 | J:274532
First Author: Ha GH
Year: 2019
Journal: Nat Commun
Title: Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks.
Volume: 10
Issue: 1
Pages: 1577
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Publication
15108799 | J:90177
First Author: Motoyama N
Year: 2004
Journal: Curr Opin Genet Dev
Title: DNA damage tumor suppressor genes and genomic instability.
Volume: 14
Issue: 1
Pages: 11-6
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Publication
19805627 | J:153811
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
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Publication
23913414 | J:210762
First Author: Kaushik Tiwari M
Year: 2013
Journal: Nucleic Acids Res
Title: XPD-dependent activation of apoptosis in response to triplex-induced DNA damage.
Volume: 41
Issue: 19
Pages: 8979-94
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Publication
26832409 | J:313428
First Author: Martini E
Year: 2016
Journal: Cell Rep
Title: Loss of Survivin in Intestinal Epithelial Progenitor Cells Leads to Mitotic Catastrophe and Breakdown of Gut Immune Homeostasis.
Volume: 14
Issue: 5
Pages: 1062-1073
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Publication
28648892 | J:309945
 
First Author: Liu R
Year: 2017
Journal: DNA Repair (Amst)
Title: ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.
Volume: 57
Pages: 29-34
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Publication
12485996 | J:320082
First Author: Mallery DL
Year: 2002
Journal: EMBO J
Title: Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains.
Volume: 21
Issue: 24
Pages: 6755-62
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Publication
11741537 | -
First Author: Jacinto E
Year: 2001
Journal: Mol Cell
Title: TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.
Volume: 8
Issue: 5
Pages: 1017-26
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Publication
23955022 | -
First Author: Wiener R
Year: 2013
Journal: Nat Struct Mol Biol
Title: E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Volume: 20
Issue: 9
Pages: 1033-9
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Publication
14636569 | J:320084
First Author: Dong Y
Year: 2003
Journal: Mol Cell
Title: Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Volume: 12
Issue: 5
Pages: 1087-99
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Publication
26195665 | -
First Author: Yan K
Year: 2015
Journal: J Cell Biol
Title: The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.
Volume: 210
Issue: 2
Pages: 209-24
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Publication
21282113 | -
First Author: Hu X
Year: 2011
Journal: J Biol Chem
Title: NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes.
Volume: 286
Issue: 13
Pages: 11734-45
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Protein Coding Gene
MGI:1277096 | Ptp4a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2654470 | Ctdsp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914694 | Ilkap
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102467 | Ptpn14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1921552 | Mtmr3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2180699 | Mtmr4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1277098 | Ptp4a3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2443300 | Cpped1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:105307 | Ptpn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916241 | Ssu72
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104673 | Ptpn12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442111 | Ppm1k
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3026877 | Ptprh
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2142330 | Ppm1n
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97813 | Ptpre
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1928376 | Ptpn9
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916524 | Ctdspl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1097157 | Ppef1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97814 | Ptprg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914853 | Dusp6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1922469 | Dusp18
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2679255 | Ssh2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915926 | Dusp22
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2441808 | Cdc14b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:105120 | Dusp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915332 | Dusp19
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442676 | Cdc14a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2686240 | Ssh1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914209 | Dusp26
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442191 | Dusp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1920797 | Dusp21
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14668445 | J:87802
First Author: Libby BJ
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice.
Volume: 100
Issue: 26
Pages: 15706-11
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Publication
15928951 | J:103876
First Author: Reinholdt LG
Year: 2005
Journal: Chromosoma
Title: Mei1 is epistatic to Dmc1 during mouse meiosis.
Volume: 114
Issue: 2
Pages: 127-34
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Publication
19137017 | J:175144
First Author: Komori K
Year: 2009
Journal: Oncogene
Title: A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA.
Volume: 28
Issue: 8
Pages: 1142-50
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Publication
20071335 | J:161081
First Author: Li DQ
Year: 2010
Journal: J Biol Chem
Title: Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway.
Volume: 285
Issue: 13
Pages: 10044-52
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Publication
22863773 | J:188614
First Author: Godon C
Year: 2012
Journal: EMBO J
Title: Generation of DNA single-strand displacement by compromised nucleotide excision repair.
Volume: 31
Issue: 17
Pages: 3550-63
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Publication
18541670 | J:137926
First Author: Bouska A
Year: 2008
Journal: Mol Cell Biol
Title: Mdm2 promotes genetic instability and transformation independent of p53.
Volume: 28
Issue: 15
Pages: 4862-74
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Publication
23484039 | J:200196
First Author: Jamin EL
Year: 2013
Journal: PLoS One
Title: Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis.
Volume: 8
Issue: 3
Pages: e58591
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Publication
25448685 | J:217529
First Author: Ganesan S
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage.
Volume: 281
Issue: 2
Pages: 203-10
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Publication
21098704 | J:166996
First Author: Gilad O
Year: 2010
Journal: Cancer Res
Title: Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.
Volume: 70
Issue: 23
Pages: 9693-702
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Publication
17220276 | J:118898
First Author: Levitt PS
Year: 2007
Journal: Mol Cell Biol
Title: Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1.
Volume: 27
Issue: 6
Pages: 2189-201
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Publication
16492765 | J:107173
First Author: Morales JC
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.
Volume: 103
Issue: 9
Pages: 3310-5
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Publication
20226664 | J:158665
First Author: Thanasoula M
Year: 2010
Journal: Curr Biol
Title: p53 prevents entry into mitosis with uncapped telomeres.
Volume: 20
Issue: 6
Pages: 521-6
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Publication
15998665 | J:100203
First Author: Bellani MA
Year: 2005
Journal: J Cell Sci
Title: SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.
Volume: 118
Issue: Pt 15
Pages: 3233-45
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Publication
33836590 | J:303259
 
First Author: Helfinger V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.
Volume: 118
Issue: 11
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Publication
15199134 | J:91596
First Author: Niedernhofer LJ
Year: 2004
Journal: Mol Cell Biol
Title: The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks.
Volume: 24
Issue: 13
Pages: 5776-87
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Publication
23811199 | J:206690
First Author: Tsunoda S
Year: 2013
Journal: Arch Biochem Biophys
Title: Differential responses of SOD1-deficient mouse embryonic fibroblasts to oxygen concentrations.
Volume: 537
Issue: 1
Pages: 5-11
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Publication
29360988 | J:260789
First Author: Abe H
Year: 2018
Journal: Hum Mol Genet
Title: CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice.
Volume: 27
Issue: 7
Pages: 1136-1149
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Publication
22575700 | J:185363
First Author: Balmus G
Year: 2012
Journal: Hum Mol Genet
Title: Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.
Volume: 21
Issue: 15
Pages: 3408-20
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Publication
25609432 | J:220994
First Author: Sauler M
Year: 2015
Journal: FASEB J
Title: Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury.
Volume: 29
Issue: 5
Pages: 1940-9
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Publication
21765465 | J:186015
First Author: Darlington Y
Year: 2012
Journal: Oncogene
Title: Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
Volume: 31
Issue: 9
Pages: 1155-65
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Publication
23519127 | J:274834
 
First Author: Bopp A
Year: 2013
Journal: Cell Death Dis
Title: Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging.
Volume: 4
Pages: e558
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Publication
21149450 | J:170406
First Author: Jeon Y
Year: 2011
Journal: J Biol Chem
Title: TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells.
Volume: 286
Issue: 7
Pages: 5414-22
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Publication
30297359 | J:271163
First Author: Chan CH
Year: 2019
Journal: Mol Cancer Res
Title: DNA Damage, Liver Injury, and Tumorigenesis: Consequences of DDX3X Loss.
Volume: 17
Issue: 2
Pages: 555-566
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Publication
17456548 | J:124198
First Author: Chicheportiche A
Year: 2007
Journal: J Cell Sci
Title: Characterization of Spo11-dependent and independent phospho-H2AX foci during meiotic prophase I in the male mouse.
Volume: 120
Issue: Pt 10
Pages: 1733-42
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Publication
23027656 | J:210068
First Author: Ma J
Year: 2013
Journal: Cardiovasc Res
Title: Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.
Volume: 97
Issue: 1
Pages: 77-87
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Publication
21840928 | J:176892
First Author: Mutsaers CA
Year: 2011
Journal: Hum Mol Genet
Title: Reversible molecular pathology of skeletal muscle in spinal muscular atrophy.
Volume: 20
Issue: 22
Pages: 4334-44
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Publication
23792460 | J:205735
First Author: Meyer N
Year: 2014
Journal: J Invest Dermatol
Title: RhoB promotes cancer initiation by protecting keratinocytes from UVB-induced apoptosis but limits tumor aggressiveness.
Volume: 134
Issue: 1
Pages: 203-212
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Publication
22355127 | J:182138
First Author: Liu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.
Volume: 109
Issue: 10
Pages: 3903-8
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Publication
26822305 | J:269108
First Author: Zhang W
Year: 2016
Journal: Toxicol Sci
Title: Loss of Mrp1 Potentiates Doxorubicin-Induced Cytotoxicity in Neonatal Mouse Cardiomyocytes and Cardiac Fibroblasts.
Volume: 151
Issue: 1
Pages: 44-56
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Publication
22308489 | J:182021
First Author: Oksenych V
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair.
Volume: 109
Issue: 7
Pages: 2455-60
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Publication
22732900 | J:187811
First Author: Boulware S
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.
Volume: 263
Issue: 2
Pages: 203-9
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Publication
35170357 | J:322937
First Author: Auyeung VC
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis.
Volume: 322
Issue: 4
Pages: L564-L580
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Publication
27930667 | J:238716
First Author: Hu MW
Year: 2016
Journal: PLoS Genet
Title: Protein Phosphatase 6 Protects Prophase I-Arrested Oocytes by Safeguarding Genomic Integrity.
Volume: 12
Issue: 12
Pages: e1006513
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Publication
26240351 | J:226564
First Author: Chen YW
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
Volume: 112
Issue: 33
Pages: E4556-64
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Publication
27982046 | J:297249
 
First Author: Ohno S
Year: 2016
Journal: Sci Rep
Title: Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2.
Volume: 6
Pages: 39091
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Publication
25296918 | J:214065
First Author: Gispert S
Year: 2015
Journal: Hum Mol Genet
Title: Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression.
Volume: 24
Issue: 4
Pages: 1061-76
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Publication
28938460 | J:249977
First Author: Fok KL
Year: 2017
Journal: Endocrinology
Title: Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response.
Volume: 158
Issue: 11
Pages: 4000-4016
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Publication
20385748 | J:161242
First Author: Santos MA
Year: 2010
Journal: J Exp Med
Title: Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.
Volume: 207
Issue: 5
Pages: 973-81
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Publication
21653549 | J:183050
First Author: Kavanaugh GM
Year: 2011
Journal: Nucleic Acids Res
Title: The human DEK oncogene regulates DNA damage response signaling and repair.
Volume: 39
Issue: 17
Pages: 7465-76
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Publication
27956701 | J:244897
 
First Author: Graveline R
Year: 2017
Journal: Mol Cell Biol
Title: The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence.
Volume: 37
Issue: 5
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Publication
16932743 | J:319983
First Author: Park JH
Year: 2006
Journal: EMBO J
Title: Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Volume: 25
Issue: 17
Pages: 3986-97
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Publication
12692309 | J:83084
First Author: Xiao H
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Acidic pH induces topoisomerase II-mediated DNA damage.
Volume: 100
Issue: 9
Pages: 5205-10
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Publication
14704340 | J:87757
First Author: Bosco EE
Year: 2004
Journal: Nucleic Acids Res
Title: RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult.
Volume: 32
Issue: 1
Pages: 25-34
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Publication
15784679 | J:97547
First Author: Townsend PA
Year: 2005
Journal: J Cell Sci
Title: STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
Volume: 118
Issue: Pt 8
Pages: 1629-39
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Publication
12866953 | J:102562
 
First Author: Noël G
Year: 2003
Journal: BMC Cell Biol
Title: Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery.
Volume: 4
Pages: 7
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Publication
18438399 | J:136293
First Author: Ayoub N
Year: 2008
Journal: Nature
Title: HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.
Volume: 453
Issue: 7195
Pages: 682-6
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Publication
19071136 | J:168938
First Author: Yajima H
Year: 2009
Journal: J Mol Biol
Title: DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.
Volume: 385
Issue: 3
Pages: 800-10
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Publication
21536735 | J:171414
First Author: Ichijima Y
Year: 2011
Journal: Genes Dev
Title: MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells.
Volume: 25
Issue: 9
Pages: 959-71
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Publication
23610439 | J:197342
First Author: Truong LN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Volume: 110
Issue: 19
Pages: 7720-5
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Publication
24850900 | J:213506
First Author: Nagarajan P
Year: 2014
Journal: Mol Cancer Res
Title: MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma.
Volume: 12
Issue: 9
Pages: 1292-302
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Publication
25489053 | J:219485
First Author: Tidball AM
Year: 2015
Journal: Hum Mol Genet
Title: A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.
Volume: 24
Issue: 7
Pages: 1929-44
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Publication
24842905 | J:223682
First Author: Tubbs AT
Year: 2014
Journal: Mol Cell Biol
Title: KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.
Volume: 34
Issue: 15
Pages: 2811-21
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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