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Search results 1201 to 1257 out of 1257 for Hand1

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Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Knöfler M
Year: 1998
Journal: Gene
Title: Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart.
Volume: 224
Issue: 1-2
Pages: 77-86
Publication
First Author: Pearton DJ
Year: 2014
Journal: Dev Biol
Title: Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression.
Volume: 392
Issue: 2
Pages: 344-57
Interaction Experiment
Description: Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2.
Interaction Experiment
Description: Sox15 enhances trophoblast giant cell differentiation induced by Hand1 in mouse placenta.
Allele
Name: transgene insertion 1, Paul R Riley
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele  
Name: myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Makoto Tanaka
Allele Type: Targeted
Allele
Name: heart and neural crest derivatives expressed 1; targeted mutation 3, Anthony B Firulli
Allele Type: Targeted
Attribute String: Conditional ready
Allele
Name: heart and neural crest derivatives expressed 1; targeted mutation 4, Anthony B Firulli
Allele Type: Targeted
Attribute String: Conditional ready
Allele
Name: transgene insertion, Anthony B Firulli
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
Strain
Attribute String: mutant stock, targeted mutation
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Myl2/Myl2<+>
Background: involves: 129X1/SvJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1<+> Tg(tetO-Hand1)1Prri/?
Background: involves: 129/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Mizugishi K
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Myogenic repressor I-mfa interferes with the function of Zic family proteins.
Volume: 320
Issue: 1
Pages: 233-40
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Publication
First Author: Kusano S
Year: 2002
Journal: Mol Cell Biol
Title: I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.
Volume: 22
Issue: 18
Pages: 6393-405
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
Publication
First Author: Thébault S
Year: 2000
Journal: J Biol Chem
Title: Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression.
Volume: 275
Issue: 7
Pages: 4848-57
Publication
First Author: Gautier VW
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Direct interaction of the human I-mfa domain-containing protein, HIC, with HIV-1 Tat results in cytoplasmic sequestration and control of Tat activity.
Volume: 102
Issue: 45
Pages: 16362-7
Publication
First Author: Young TM
Year: 2003
Journal: Mol Cell Biol
Title: The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
Volume: 23
Issue: 18
Pages: 6373-84
Protein Domain
Type: Family
Description: This family consists of MyoD family inhibitor (I-mfa, MDFI) and MyoD family inhibitor domain-containing protein. I-mfa acts as a transcriptional activator or repressor. It retains nuclear Zic family proteins (ZIC1, ZIC2 and ZIC3) in the cytoplasm and consequently inhibits their transcriptional activation ability []. I-mfa domain-containing protein interacts with HAND1 (bHLH transcription factor), leading to sequester HAND1 into the nucleolus and prevent its activity []. In humans modulates the expression from both cellular and viral promoters. It down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. It also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR [, , ]. Both I-mfa and I-mfa domain-containing protein interact with the axin complex and affect axin regulation of both the Wnt and the JNK activation pathways [].
Allele
Name: heart and neural crest derivatives expressed 1; targeted mutation 2.1, Anthony B Firulli
Allele Type: Targeted
Attribute String: Hypomorph
Allele  
Name: heart and neural crest derivatives expressed 1; targeted mutation 2, Anthony B Firulli
Allele Type: Targeted
Genotype
Symbol: Hand1/Hand1<+> Tg(Mpz-cre)94Imeg/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1 Hand2/Hand2
Background: involves: 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1 E2f1/E2f1<+>
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1<+> E2f1/E2f1<+>
Background: involves: C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1<+> E2f1/E2f1<+>
Background: involves: C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hand1/Hand1 E2f1/E2f1<+>
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Hand1-EGFP/cre)#Abfi/?
Background: involves: 129S4/SvJaeSor * C3HeB/FeJ
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Karantzali E
Year: 2011
Journal: J Biol Chem
Title: Sall1 regulates embryonic stem cell differentiation in association with nanog.
Volume: 286
Issue: 2
Pages: 1037-45
Publication
First Author: Lewis AL
Year: 1999
Journal: J Biol Chem
Title: Combinatorial interactions regulate cardiac expression of the murine adenylosuccinate synthetase 1 gene.
Volume: 274
Issue: 20
Pages: 14188-97