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Search results 1201 to 1300 out of 2139 for Lck

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Type Details Score
Publication
19628763 | J:150941
First Author: Dewals B
Year: 2009
Journal: Am J Pathol
Title: IL-4Ralpha responsiveness of non-CD4 T cells contributes to resistance in schistosoma mansoni infection in pan-T cell-specific IL-4Ralpha-deficient mice.
Volume: 175
Issue: 2
Pages: 706-16
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Publication
22411629 | J:185745
First Author: Gegonne A
Year: 2012
Journal: Mol Cell Biol
Title: The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.
Volume: 32
Issue: 10
Pages: 1984-97
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Publication
30899267 | J:294448
 
First Author: Behr FM
Year: 2019
Journal: Front Immunol
Title: Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8+ T Cells in the Lungs.
Volume: 10
Pages: 400
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Publication
27634043 | J:314799
First Author: Lykken EA
Year: 2016
Journal: J Biol Chem
Title: The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling.
Volume: 291
Issue: 45
Pages: 23532-23544
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Publication
22069310 | J:332362
First Author: Luo H
Year: 2011
Journal: J Biol Chem
Title: Ephrinb1 and Ephrinb2 are associated with interleukin-7 receptor α and retard its internalization from the cell surface.
Volume: 286
Issue: 52
Pages: 44976-87
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Publication
28062573 | J:273992
First Author: Rampoldi F
Year: 2017
Journal: J Leukoc Biol
Title: Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-γ-producing γδ T cells.
Volume: 101
Issue: 4
Pages: 1005-1014
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Publication
18635581 | J:139042
First Author: Tian L
Year: 2008
Journal: Int Immunol
Title: ADAM10 is essential for proteolytic activation of Notch during thymocyte development.
Volume: 20
Issue: 9
Pages: 1181-7
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Publication
36189299 | J:334196
 
First Author: Juarez I
Year: 2022
Journal: Front Immunol
Title: Splicing factor SRSF1 is essential for CD8 T cell function and host antigen-specific viral immunity.
Volume: 13
Pages: 906355
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Publication
32810232 | J:316330
First Author: Katsuyama T
Year: 2021
Journal: Rheumatology (Oxford)
Title: Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis.
Volume: 60
Issue: 1
Pages: 420-429
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Publication
31487268 | J:284098
First Author: Katsuyama T
Year: 2019
Journal: J Clin Invest
Title: Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.
Volume: 129
Issue: 12
Pages: 5411-5423
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Publication
29891553 | J:264059
First Author: Gibson SA
Year: 2018
Journal: J Immunol
Title: CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1.
Volume: 201
Issue: 2
Pages: 383-392
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Publication
34839165 | J:319669
 
First Author: Cassidy MF
Year: 2022
Journal: Mol Immunol
Title: Splicing factor SRSF1 controls distinct molecular programs in regulatory and effector T cells implicated in systemic autoimmune disease.
Volume: 141
Pages: 94-103
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Publication
19047679 | J:145543
First Author: Nakayama J
Year: 2009
Journal: Blood
Title: BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3.
Volume: 113
Issue: 7
Pages: 1483-92
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Publication
27974197 | J:241713
First Author: Rauch KS
Year: 2016
Journal: Cell Rep
Title: Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a Transcriptional Network of E47, Spi-B, and SOCS3.
Volume: 17
Issue: 11
Pages: 2827-2836
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Publication
28424246 | J:243973
First Author: Moffitt AB
Year: 2017
Journal: J Exp Med
Title: Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.
Volume: 214
Issue: 5
Pages: 1371-1386
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Publication
28258199 | J:247735
First Author: Li J
Year: 2017
Journal: J Immunol
Title: Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors.
Volume: 198
Issue: 8
Pages: 3136-3148
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Publication
23362346 | J:194053
First Author: Liu B
Year: 2013
Journal: Development
Title: Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Volume: 140
Issue: 4
Pages: 780-8
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Publication
20224552 | J:160381
First Author: Lee AJ
Year: 2010
Journal: EMBO J
Title: Regulation of natural killer T-cell development by deubiquitinase CYLD.
Volume: 29
Issue: 9
Pages: 1600-12
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Publication
20431622 | J:160612
First Author: Chang HC
Year: 2010
Journal: Nat Immunol
Title: The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Volume: 11
Issue: 6
Pages: 527-34
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Publication
21779390 | J:175789
First Author: Jabeen R
Year: 2011
Journal: PLoS One
Title: The transcription factor PU.1 regulates γδ T cell homeostasis.
Volume: 6
Issue: 7
Pages: e22189
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Publication
19801513 | J:153816
First Author: Chang HC
Year: 2009
Journal: J Immunol
Title: PU.1 regulates TCR expression by modulating GATA-3 activity.
Volume: 183
Issue: 8
Pages: 4887-94
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Publication
26363052 | J:324560
First Author: Awe O
Year: 2015
Journal: J Immunol
Title: PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development.
Volume: 195
Issue: 8
Pages: 3705-15
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Publication
21168915 | J:168475
First Author: Fu T
Year: 2011
Journal: Mol Immunol
Title: Accelerated acute allograft rejection accompanied by enhanced T-cell proliferation and attenuated Treg function in RBP-J deficient mice.
Volume: 48
Issue: 5
Pages: 751-9
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Publication
30619297 | J:303419
 
First Author: Amersfoort J
Year: 2018
Journal: Front Immunol
Title: Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis.
Volume: 9
Pages: 2937
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Publication
33310872 | J:303911
First Author: Sumiyoshi M
Year: 2021
Journal: J Immunol
Title: Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation.
Volume: 206
Issue: 2
Pages: 366-375
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Strain
MGI:5302835 | B6.Cg-Efnb2<tm1.1Jwu> Tg(Lck-cre)I540Jxm
Attribute String: targeted mutation, transgenic, mutant strain, congenic
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Strain
MGI:5302675 | B6.Cg-Efnb1<tm1.1Jwu> Tg(Lck-cre)I540Jxm
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
22673212 | J:188166
First Author: Jin W
Year: 2012
Journal: Mol Immunol
Title: T cell-specific deletion of EFNB2 minimally affects T cell development and function.
Volume: 52
Issue: 3-4
Pages: 141-7
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Publication
35906240 | J:328286
First Author: Zhong W
Year: 2022
Journal: Nat Commun
Title: An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis.
Volume: 13
Issue: 1
Pages: 4390
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Publication
15944278 | J:100879
First Author: Goetz CA
Year: 2005
Journal: J Immunol
Title: Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment.
Volume: 174
Issue: 12
Pages: 7753-63
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Publication
20620941 | J:161995
First Author: Lee K
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Volume: 32
Issue: 6
Pages: 743-53
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Allele
Lck<m2Btlr> | MGI:5528710
 
Name: lymphocyte protein tyrosine kinase; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Strain
MGI:5568764 | FVB.Cg-Tg(Cspg4-EGFP*)HDbe/J
Attribute String: congenic, mutant strain, transgenic
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Publication
23624515 | J:209866
First Author: Hughes EG
Year: 2013
Journal: Nat Neurosci
Title: Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain.
Volume: 16
Issue: 6
Pages: 668-76
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Strain
MGI:5806655 | C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-GCaMP6f)Khakh>/J
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Tg(Lck-RHO/ADRA1,-lacZ)B22-1Mik | MGI:6361521
Name: transgene insertion B22-1, M I Kotlikoff
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Mcl1/Mcl1 Tg(Lck-cre)1Cwi/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Birc5/Birc5 Tg(Lck-cre)1Cwi/?
Background: involves: 129S/SvEv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myb/Myb Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myb/Myb Tg(Lck-cre)548Jxm/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cbl/Cbl Cblb/Cblb Tg(Lck-cre)I57Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd4/Cd4 Tg(Lck-cre)3778Nik/?
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd4/Cd4 Tg(Lck-icre)3779Nik/?
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mapk1/Mapk1 Mapk3/Mapk3 Tg(Lck-cre)1Cwi/?
Background: involves: 129/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Lck-cre)548Jxm/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chd4/Chd4 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Was/Was Wasl/Wasl Tg(Lck-cre)1Cwi/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tcf3/Tcf3 Tg(Lck-cre)#Zhu/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tcf3/Tcf3 Tg(Lck-Stat5b*)1Mafa/?
Background: involves: 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Lck-cre)I57Jxm/? Traf3/Traf3
Background: involves: C57BL/6 * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cops5/Cops5 Tg(Lck-cre)548Jxm/? Trp53/Trp53
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag2/Rag2 Tg(Lck-Akt1*)M-1Pnt/?
Background: involves: 129S/SvEv * C3H/He * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Tg(Lck-Akt1*E40K)E-3Pnt/?
Background: involves: 129S7/SvEvBrd * C3H/He * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trpm7/Trpm7 Tg(Lck-cre)548Jxm/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctcf/Ctcf Tg(Lck-cre)1Cwi/? Tg(TcraTcrb)425Cbn/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smarca4/Smarca4<+> Tg(Lck-cre)1Cwi/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca2/Brca2 Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(Lck-cre)548Jxm/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Cdkn1a/Cdkn1a Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Tg(Lck-cre)548Jxm/? Tg(TcrLCMV)327Sdz/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Chek2/Chek2 Tg(Lck-cre)548Jxm/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(B2M)55Hpl/? Tg(CD8aCD8b)57Scr/? Tg(HLA-B)22Hpl/?
Background: involves: C57BL/6 * C57BL/LiA * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map3k3/Map3k3 Tg(Lck-cre)548Jxm/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgef12/Arhgef12 Tg(Lck-cre)548Jxm/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gna12/Gna12 Gna13/Gna13 Tg(Lck-cre)548Jxm/?
Background: involves: 129S1/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Lck-Tnfsf14)24Yxf/? Tnfrsf14/Tnfrsf14
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tgfb1/Tgfb1 Tg(Lck-cre)548Jxm/?
Background: involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * BALB/c * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EEF1A1-SHC1*)1Ravi/? Tg(Lck-cre)1Cwi/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fadd/Fadd Tg(Fadd)33Wnt/? Tg(Lck-cre)I57Jxm/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk4/Stk4 Tg(Lck-cre)#Zhu/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd19/Cd19<+> Ltbr/Ltbr Tg(Lck-cre)I57Jxm/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Grb2/Grb2 Tg(DO11.10)10Dlo/? Tg(Lck-cre)1Jtak/?
Background: involves: 129 * BALB/c * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkcq/Prkcq Tg(LCKprBCL2L1)12Sjk/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbpj/Rbpj Tg(Lck-cre)19Hhan/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Efnb1/Efnb1 Tg(Lck-cre)I540Jxm/?
Background: B6.Cg-Efnb1 Tg(Lck-cre)I540Jxm
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Efnb2/Efnb2 Tg(Lck-cre)I540Jxm/?
Background: B6.Cg-Efnb2 Tg(Lck-cre)I540Jxm
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr7/Rr7<+> Tg(Lck-cre)#Nik/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Relb/Relb Tg(Lck-cre)I57Jxm/?
Background: involves: ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nr3c1/Nr3c1 Tcra/Tcra Tg(Lck-cre)548Jxm/?
Background: B6.Cg-Tcra Nr3c1 Tg(Lck-cre)548Jxm
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mirc14/Mirc14 Tg(LCKprBCL2L1)12Sjk/?
Background: involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bak1/Bak1 Bax/Bax Tg(Lck-cre)548Jxm/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Tcrb-TCF3/PBX1)23Gusa/?
Background: involves: C3H * C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Tcrb-TCF3/PBX1)19Gusa/?
Background: involves: C3H * C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nmt1/Nmt1 Nmt2/Nmt2 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6 * DBA/2 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkd2/Prkd2 Prkd3/Prkd3 Tg(BCL2)25Wehi/? Tg(Lck-cre)1Jtak/?
Background: involves: 129 * C57BL/6 * C57BL/6JWehi * SJL/JWehi
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nop53/Nop53 Trp53/Trp53 Tg(Lck-cre)#Jxm/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnf/Tnf Cd19/Cd19<+> Tg(Lck-cre)1Jtak/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lck-cre)1Cwi/? Tg(TetO-Axin1,-EGFP)TA32Cos/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prdm1/Prdm1 Zfp683/Zfp683 Tg(Lck-cre)1Cwi/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Protein
Q9DCU2
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: false
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Protein
Q91X49
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
O09198
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
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Protein
Q9CZR4
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Publication
9551546 | -
First Author: Barford D
Year: 1998
Journal: Structure
Title: Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.
Volume: 6
Issue: 3
Pages: 249-54
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Publication
7935426 | J:21333
First Author: Hahm K
Year: 1994
Journal: Mol Cell Biol
Title: The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene.
Volume: 14
Issue: 11
Pages: 7111-23
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Publication
11522790 | J:159012
First Author: Hanada T
Year: 2001
Journal: J Biol Chem
Title: A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.
Volume: 276
Issue: 44
Pages: 40746-54
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Publication
18641339 | J:139245
First Author: Lapinski PE
Year: 2008
Journal: J Immunol
Title: Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells.
Volume: 181
Issue: 3
Pages: 2019-27
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Publication
16143319 | J:107956
First Author: Tian W
Year: 2005
Journal: Cell Immunol
Title: Silencing OCILRP2 leads to intrinsic defects in T cells in response to antigenic stimulation.
Volume: 235
Issue: 1
Pages: 72-84
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Publication
12610126 | J:343103
First Author: Hahm B
Year: 2003
Journal: J Virol
Title: Measles virus infects and suppresses proliferation of T lymphocytes from transgenic mice bearing human signaling lymphocytic activation molecule.
Volume: 77
Issue: 6
Pages: 3505-15
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Publication
19542440 | J:149973
First Author: Gatzka M
Year: 2009
Journal: J Immunol
Title: Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development.
Volume: 183
Issue: 1
Pages: 285-97
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