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Search results 1201 to 1300 out of 2191 for MBP

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Type Details Score
Publication
32857879 | J:332131
First Author: Perera SN
Year: 2020
Journal: Glia
Title: Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Volume: 68
Issue: 12
Pages: 2550-2584
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Publication
17145500 | J:144660
First Author: Yoshida Y
Year: 2006
Journal: Neuron
Title: PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.
Volume: 52
Issue: 5
Pages: 775-88
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Publication
25131634 | J:238190
First Author: Alldred MJ
Year: 2015
Journal: J Comp Neurol
Title: Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
Volume: 523
Issue: 1
Pages: 61-74
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Publication
17634366 | J:145263
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
24154525 | J:205051
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Tg(Mbp-SNCA)29Ema | MGI:5634090
Name: transgene insertion 29, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Mbp-SNCA)1Ema | MGI:5634092
Name: transgene insertion 1, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
11880156 | J:132051
First Author: Song F
Year: 2002
Journal: J Neuroimmunol
Title: Activation of Vbeta8 T cells affects spontaneous EAE in MBP TCR transgenic mice.
Volume: 123
Issue: 1-2
Pages: 112-22
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Publication
18817874 | J:143357
First Author: Kobayashi H
Year: 2008
Journal: Mol Cell Neurosci
Title: MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage.
Volume: 39
Issue: 4
Pages: 619-27
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Interaction Term
MI:0578 | maltose binding protein tag
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Publication
25451297 | J:221446
 
First Author: Meffre D
Year: 2015
Journal: Neuroscience
Title: Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways.
Volume: 284
Pages: 962-71
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Publication
9628462 | J:48413
First Author: Pedchenko TV
Year: 1998
Journal: J Neuroimmunol
Title: Desferrioxamine suppresses experimental allergic encephalomyelitis induced by MBP in SJL mice.
Volume: 84
Issue: 2
Pages: 188-97
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Protein
P04370
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
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Allele
Tg(Tcra19,Tcrb19)#Caj | MGI:5909277
Name: transgene insertion, Charles A Janeway
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
9282330 | -
First Author: Muralidharan V
Year: 1997
Journal: J Cell Biochem
Title: Evidence for inhibition of MyEF-2 binding to MBP promoter by MEF-1/Pur alpha.
Volume: 66
Issue: 4
Pages: 524-31
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Transgene
MGI:5634089 | Tg(Mbp-SNCA)29Ema
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5634091 | Tg(Mbp-SNCA)1Ema
Type: transgene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6423519
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3281527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7524126
Age: postnatal day 1
Image: 3K/M
Note: Polarized, ab-axonal (ring) pattern of expression on surface of myelinating Schwann cells, and cells still negative for Mbp expression.
Specimen Label: 3K/M
Detected: true
Specimen Num: 7
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Publication
11145205 | -
First Author: Campagnoni AT
Year: 2001
Journal: Brain Pathol
Title: The pathobiology of myelin mutants reveal novel biological functions of the MBP and PLP genes.
Volume: 11
Issue: 1
Pages: 74-91
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Protein
P04370-14
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Protein
P04370-4
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
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Protein
P04370-7
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
P04370-9
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
P04370-10
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
P04370-13
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
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Protein
P04370-5
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: false
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Protein
P04370-8
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
P04370-6
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
P04370-11
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
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Protein
P04370-3
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
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Protein
P04370-2
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
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Publication
31722009 | J:289749
First Author: Candreva T
Year: 2019
Journal: Clin Sci (Lond)
Title: Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue.
Volume: 133
Issue: 22
Pages: 2345-2360
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Publication
16361316 | J:104159
First Author: Kurschus FC
Year: 2006
Journal: Int Immunol
Title: Experimental autoimmune encephalomyelitis in mice expressing the autoantigen MBP 1-10 covalently bound to the MHC class II molecule I-Au.
Volume: 18
Issue: 1
Pages: 151-62
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Publication
12150894 | -
First Author: He XL
Year: 2002
Journal: Immunity
Title: Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au.
Volume: 17
Issue: 1
Pages: 83-94
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GO Term
GO:0004707 | MAP kinase activity
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Publication
34587386 | J:341542
First Author: Chai G
Year: 2021
Journal: N Engl J Med
Title: A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.
Volume: 385
Issue: 14
Pages: 1292-1301
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Allele
Mbp<em1Smoc> | MGI:7290995
Name: myelin basic protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6355011 | C57BL/6JSmoc-Mbp<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Mbp-OVAL)2Huen | MGI:7494183
Name: transgene insertion 2, Thomas Hunig
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Mbp-OVAL)7Huen | MGI:7494185
Name: transgene insertion 7, Thomas Hunig
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein
Q542T4
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Q09J72
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Protein
Q5D096
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
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Protein
A0A411P8U6
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: true
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Protein
Q3UGF3
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
A0A498WGS3
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Publication
1710177 | -
First Author: Deber CM
Year: 1991
Journal: Clin Biochem
Title: Central nervous system myelin: structure, function, and pathology.
Volume: 24
Issue: 2
Pages: 113-34
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Protein Domain
IPR000548 | Myelin_BP
Type: Family
Description: The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction []. Myelin basic protein (MBP) [, ]is a hydrophilic protein that may function to maintain the correct structure of myelin, interacting with the lipids in the myelin membrane by electrostatic and hydrophobic interactions. In mammals various forms of MBP exist which are produced by the alternative splicing of a single gene; these forms differ by the presence or the absence of short (10 to 20 residues) peptidesin various internal locations in the sequence. The major form of MBP is generally a protein of about 18.5 Kd (170 residues). MBP is the target of many post-translational modifications: it is N-terminally acetylated, methylated on an arginine residue, phosphorylated by various serine/threonine protein-kinases, and deamidated on some glutamine residues.
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Publication
26179797 | J:303278
First Author: Raman P
Year: 2015
Journal: Thyroid
Title: Identification of the Genomic Insertion Site of the Thyroid Peroxidase Promoter-Cre Recombinase Transgene Using a Novel, Efficient, Next-Generation DNA Sequencing Method.
Volume: 25
Issue: 10
Pages: 1162-6
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Allele
Igk<tm1(IGK)Vlcg> | MGI:5610003
Name: immunoglobulin kappa chain complex; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Allele
Igk<tm2(IGK)Vlcg> | MGI:5610004
Name: immunoglobulin kappa chain complex; targeted mutation 2, Velocigene
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Publication
11746955 | J:72648
First Author: Sato M
Year: 2001
Journal: Mol Reprod Dev
Title: Usefulness of double gene construct for rapid identification of transgenic mice exhibiting tissue-specific gene expression.
Volume: 60
Issue: 4
Pages: 446-56
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Protein Domain
IPR034630 | MYEF2_RRM1
Type: Domain
Description: This entry represents the RNA recognition motif 1 (RRM1) of MEF-2 (also known as MyEF-2), a sequence-specific single-stranded DNA (ssDNA) binding protein that binds specifically to ssDNA derived from the proximal (MB1) element of the myelin basic protein (MBP) promoter and represses transcription of the MBP gene [, ]. MEF-2 contains three RNA recognition motifs (RRMs).
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Protein Domain
IPR034631 | MYEF2_RRM3
Type: Domain
Description: This entry represents the RNA recognition motif 3 (RRM3) of MEF-2 (also known as MyEF-2), a sequence-specific single-stranded DNA (ssDNA) binding protein that binds specifically to ssDNA derived from the proximal (MB1) element of the myelin basic protein (MBP) promoter and represses transcription of the MBP gene [, ]. MEF-2 contains three RNA recognition motifs (RRMs).
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Publication
19093029 | J:142650
First Author: Musse AA
Year: 2008
Journal: Dis Model Mech
Title: Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system.
Volume: 1
Issue: 4-5
Pages: 229-40
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HT Experiment
E-GEOD-51230 | Glomerulonephritis in BXSB/MpJ-Yaa mice
Series Id: GSE51230
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
2323577 | -
First Author: Barker RL
Year: 1990
Journal: Gene
Title: Cloning and sequence analysis of the human gene encoding eosinophil major basic protein.
Volume: 86
Issue: 2
Pages: 285-9
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Publication
3410852 | -
First Author: Wasmoen TL
Year: 1988
Journal: J Biol Chem
Title: Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein.
Volume: 263
Issue: 25
Pages: 12559-63
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Publication
1565101 | -
First Author: Yoshimatsu K
Year: 1992
Journal: Mol Immunol
Title: Purification and cDNA cloning of a novel factor produced by a human T-cell hybridoma: sequence homology with animal lectins.
Volume: 29
Issue: 4
Pages: 537-46
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Protein Domain
IPR002352 | Eosinophil_major_basic
Type: Family
Description: Eosinophil granule major basic protein (MBP) is a low molecular weight cationic protein present in the crystalloid core of the eosinophil granule[]. It is a potent toxin for helminths and mammalian cells, and may have important roles in allergic and inflammatory reactions, it can release histamine from mast cells and damage epithelial cells of bronchial tubes.MBP is also involved in antiparasitic defence mechanisms and immune hypersensitivity reactions. The protein is a single arginine-rich polypeptide[], its pro-portion being rich in glutamic and aspartic acids. It has been suggested that the protein is translated as a nontoxic precursor that protects the eosinophil from damage while it is processed through the endoplasmic reticulum to its sequestered site in the granule core toxic MBP []. The sequence of MBP has been shown to contain a C-type lectin (CTL) domain []. CTL domains are 110-130 residue motifs that appear to function as calcium-dependent carbohydrate-recognition domains [, , ].
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Publication
22801375 | J:188791
First Author: van Riel B
Year: 2012
Journal: Mol Cell Biol
Title: A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.
Volume: 32
Issue: 19
Pages: 3814-22
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Protein Domain
IPR034632 | MYEF2
Type: Family
Description: MEF-2 (also known as MyEF-2) is a sequence-specific single-stranded DNA (ssDNA) binding protein that binds specifically to ssDNA derived from the proximal (MB1) element of the myelin basic protein (MBP) promoter and represses transcription of the MBP gene [, ]. MEF-2 contains two RNA recognition motifs (RRMs). MEF-2 is also a binding partner of RUNX1 during erythropoiesis, which is bound in undifferentiated cells and lost upon differentiation [].
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Allele
Mbp<shi-mld+> | MGI:1857657
 
Name: myelin basic protein; wild type revertant
Allele Type: Spontaneous
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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